Top Machine Learning Jobs in Buffalo, NY

Leads the enterprise data strategy, builds and scales the Data & Analytics team, and oversees data warehouse modernization, migration, governance, KPI standardization, and data quality. Partners with executives and cross-functional teams to convert data into actionable insights, operational improvements, predictive analytics, and AI-enabled workflows. The role requires hands-on Python, SQL, cloud, machine learning, and ETL expertise, plus strong leadership and communication skills.

Leads a data science team and personally drives analyses, experimentation, and product analytics to identify patient experience improvements. Partners with Product, Engineering, Research, and Data Engineering teams to develop product features, evaluate business and product performance, guide product planning, and translate statistical findings into actionable recommendations. Manages and develops analytical talent while applying data storytelling, A/B testing, marketplace metrics, and retention, conversion, engagement, and churn analysis.

Develops, calibrates, validates, and maintains credit risk models, including PD, LGD, and EAD models, for lending, collections, loss forecasting, capital planning, and stress testing. Analyzes large datasets, evaluates model performance, documents model changes, supports systems testing, and communicates statistical insights to stakeholders and management. Collaborates across the credit union to improve risk-return strategies and reporting.

Leads Lyra Health’s AI/ML engineering roadmap, scales and mentors machine learning teams, and drives production-grade systems for clinical applications. Responsibilities include people leadership, quarterly planning, technical architecture, design reviews, model governance, ML SDLC oversight, and deployment of reliable microservices on Kubernetes. The role partners with product, data science, and clinical stakeholders while ensuring safety, operational excellence, cloud scalability, and compliance for sensitive healthcare data.

Leads enterprise AI tooling and security engineering, designing scalable cloud platforms and secure AI applications. Responsibilities include protecting models, agents, prompts, data, APIs, and outputs; securing the AI/ML lifecycle; implementing identity, encryption, monitoring, threat detection, adversarial testing, and incident response; and establishing engineering standards. The role mentors engineers, influences architecture and technology strategy, and partners with governance, risk, compliance, and business teams to support responsible AI adoption.

Leads complex enterprise SaaS delivery programs for major banks, owning governance, client and executive relationships, commercial controls, risk management, regulatory deadlines, third-party coordination, and successful go-live. The role requires deep financial crime compliance technology experience, including AML, KYC, transaction monitoring, sanctions screening, or case management platforms, plus proven Tier 1 bank implementations, program turnaround expertise, cloud delivery, and senior stakeholder credibility.

Lead independent validation and ongoing monitoring of complex financial and analytics models, including ALM, loss forecasting, loan transition, corporate finance, and engagement models. Identify weaknesses, communicate findings, guide remediation, and strengthen model governance. Collaborate with Finance, Quantitative Research, Growth Analytics, Internal Audit, Internal Controls, Accounting, and Compliance to maintain Affirm’s model risk framework and address audit, regulatory, and examiner requests.

Leads KeyBank’s Red Team and offensive security program, including adversary emulation, penetration testing, physical and application assessments, cloud security testing, AI security evaluations, and purple team exercises. Develops testing strategy, methodologies, tooling, metrics, and maturity roadmaps; mentors engineers; coordinates internal and third-party engagements; validates remediation and attack paths; and presents findings and strategic recommendations to executives and cybersecurity stakeholders.

Lead G2’s experimentation practice across products and digital marketplaces. Design experimentation standards, causal inference methods, metrics, guardrails, and analysis approaches; partner with product and engineering to implement experimentation platforms and instrumentation. Build models, design auctions, ship production systems, evaluate modern statistical methods, and address marketplace interference and low-traffic constraints. Mentor data scientists and evangelize rigorous data science practices across the organization.

Leads Kapitus’ core lending product portfolio, including term loans and lines of credit. Owns product P&L, strategy, pricing, go-to-market execution, competitive intelligence, roadmap prioritization, regulatory alignment, and financial outcomes. Partners with Product Delivery, Risk, Finance, Sales, Marketing, Operations, Compliance, and executives. Manages and develops a team of product managers while identifying opportunities for AI and machine learning to improve underwriting, decisioning, offers, and borrower communications.

Leads Tala’s Machine Learning Engineering team in building and operating platforms for model development, real-time inference, streaming features, batch processing, deployment, monitoring, and production reliability. Manages and develops 4–6 engineers, owns delivery and prioritization, provides architectural leadership, improves engineering practices and SLOs, and partners with Data Science, Data Engineering, Product, Credit, and Business Development teams.

Leads enterprise innovation strategy and cross-domain solution architecture across AI, data, cloud, software engineering, ITSM, DevSecOps, and cybersecurity. Designs scalable, secure solutions; develops reusable accelerators and innovation frameworks; supports federal proposals, capture efforts, and technical writing; advises senior government stakeholders; and drives cross-functional collaboration, capability development, and technology adoption in GovCon environments.

Develop and lead data science and machine learning initiatives, including exploratory analysis, predictive modeling, experimentation, recommendation systems, user classification, model monitoring, and production deployment. Partner with product, marketing, analytics, and engineering teams to convert user insights into automated services. Manage projects throughout their lifecycle, support strategic ML planning, and deliver solutions for personalization, cross-selling, and retargeting.

Consult as a fractional data scientist for hedge funds, private equity firms, and family offices. Lead data science initiatives: build infrastructure, develop and deploy models, create portfolio dashboards, monitor post-deployment performance, and partner with investment teams to turn data into actionable investment insights. Advise on vendor selection, data quality, technology stacks, KPIs, and governance.

Lead positioning, messaging, go-to-market strategy, launches, channel enablement, competitive intelligence, and analyst relations for Sophos’ AI cybersecurity solutions. Translate complex technical capabilities into buyer- and partner-focused narratives, build launch assets and sales tools, and coordinate cross-functional execution across product, sales, marketing, and research teams. The role also develops customer feedback loops, competitive battlecards, and category-defining market perspectives.

Lead load and generation interconnection studies, including steady-state, short-circuit, and dynamic analyses. Develop power-flow and stability models, establish study methodologies, evaluate system upgrades and grid-enhancing technologies, and present recommendations to utilities, developers, regulators, and customers. Serve as a power systems subject-matter expert, help connect planning assessments with utility operations, and collaborate with AI and automation teams to improve study efficiency and accuracy.

Leads enterprise data, analytics, business intelligence, and AI strategy across healthcare payer functions. Partners with executives to prioritize analytics initiatives, build reporting and predictive insight capabilities, establish data governance and accountability, and drive measurable business outcomes. Oversees cross-functional teams, enterprise application development, Azure architecture, quality automation, DevOps, and intelligent automation while engaging C-suite and board stakeholders.

Leads the development of partner enablement programs for Databricks and Snowflake ecosystems. Establishes strategies, governance, stakeholder relationships, learning pathways, workshops, bootcamps, champion networks, and readiness frameworks for technical and business audiences. Translates data, AI, analytics, and lakehouse use cases into scalable learning experiences, aligns programs with partnership growth objectives, measures engagement and effectiveness, and continuously improves initiatives based on partner feedback and business impact.

The Enterprise Account Executive will drive revenue growth by managing complex sales cycles, closing deals with Fortune 500 companies, and understanding both technical and business needs.

Leads complex technical programs supporting government and defense missions, managing scope, schedules, budgets, risks, customer relationships, and multidisciplinary teams. Provides technical direction across software development, cloud architecture, data engineering, operations research, analytics, and decision support. Oversees modeling, optimization, machine learning, dashboards, and executive recommendations while engaging senior government stakeholders. Supports proposals, capture activities, technical reviews, and continuous improvement initiatives.

Collects and analyzes performance data, identifies trends, evaluates program effectiveness, and develops reports and visualizations for stakeholders. The role standardizes datasets, improves data collection and analytical methods, and supports data-driven decisions. It requires statistical analysis, data manipulation, visualization, and familiarity with machine learning and predictive analytics. The position is contingent on contract award and requires the ability to obtain and maintain an active Secret Clearance.

Leads business insights and analytics for Rocket Pharma’s gene therapy portfolio, with emphasis on rare cardiology. Responsibilities include disease modeling, patient-identification analytics, forecasting, market research, real-world data integration, analytics platform development, and market-development strategy. The role partners cross-functionally with IT, vendors, field teams, and external analytics providers while translating fragmented data into strategic recommendations and ensuring compliant use of analytics and market research investments.

Builds a talent network of experienced data scientists for potential future AI evaluation projects. Responsibilities may include creating grading criteria, evaluating AI-generated or human-produced data science work, writing evidence-based justifications, applying consistent judgment, and incorporating reviewer feedback. Candidates should have professional data science experience, strong Python and SQL skills, expertise in statistical modeling, machine learning, experimentation, causal inference, and excellent technical communication.

Designs and supports scalable cloud data warehouses for CMS healthcare fraud, waste, and abuse analytics. Responsibilities include data modeling, healthcare interoperability, secure HIPAA-compliant governance, lineage, testing, CI/CD, automation, workflow scheduling, and technical architecture. The role integrates claims and healthcare domains using Snowflake and industry standards while collaborating with stakeholders, documenting solutions, and leading warehouse project delivery.

Partner with healthcare clients to design, prototype, and deploy production-grade AI/LLM solutions. Lead discovery, architecture, cloud integration, and delivery while troubleshooting distributed systems and driving measurable client outcomes.