Top Senior Data Science Jobs in Buffalo, NY

Own the analytical function for a core business area such as growth, product, AI and automation, or strategic partnerships. Define business questions, metrics, reports, analyses, and experiments; generate insights; and drive data-informed decisions with cross-functional stakeholders. The role requires independently structuring ambiguous problems, using SQL or Python, communicating findings clearly, and delivering measurable business impact.

Develop and deploy predictive and causal models for personalization, retention, monetization, and product strategy. Design experimentation and measurement frameworks, analyze user and marketing behavior, quantify business impact, and translate complex findings into strategic decisions. Collaborate with Product, Engineering, Marketing, and Data Product teams to build scalable data solutions. Mentor peers, promote rigorous model validation and governance, and apply Python, SQL, Snowflake, dbt, Airflow, Spark, and AWS to production-ready data science initiatives.

Seeking a skilled Data Scientist/Machine Learning Engineer to develop machine learning models, design AI systems, and collaborate in data analytics. Responsibilities include productionizing models, data engineering, and cross-functional collaboration.

Lead the design, development, deployment, and governance of advanced analytics, machine learning, and AI solutions using large healthcare datasets. Responsibilities include data preparation, statistical and predictive modeling, model monitoring, explainability, visualization, stakeholder communication, and translating findings into clinical and operational improvements. The role also mentors data professionals, advises leaders, manages initiative priorities and risks, and promotes responsible AI and Agile practices.

Lead the technical development and automation of enrollment forecasting models, collaborating with various departments to enhance decision-making and forecast accuracy.

Design and deploy ML systems for enterprise search, recommendations, retrieval, and AI agents. Build scalable data/ML pipelines, evaluation frameworks, and metrics. Apply statistics, experimentation, and causal inference to guide product decisions. Collaborate cross-functionally, prototype LLM-based capabilities (embeddings, RAG), and mentor junior team members.

Lead design and deployment of ML systems for enterprise search, retrieval, recommendations, and AI agents. Build scalable data/ML pipelines, evaluation frameworks, and KPIs. Apply statistics, causal inference, experimentation, and analysis to guide product strategy. Prototype and productionize LLM-based features, mentor junior staff, and collaborate cross-functionally.

As a Senior Data Scientist, you'll optimize search relevance, retrieve content, analyze data, and collaborate with teams to enhance product strategies.

Lead design and production deployment of ML models focused on pricing, availability, forecasting, and optimization. Build data infrastructure, governance, testing/monitoring, and dashboards. Partner with executives and cross-functional teams, mentor others, and establish scalable data-science practices and experimentation frameworks.

Build and deploy end-to-end ML models for renter acquisition, supply optimization, ranking, personalization, and marketplace optimization. Lead technical projects from problem framing through experimentation, launch, monitoring, and iteration. Apply statistical methods, causal inference, and rigorous A/B testing. Partner cross-functionally, mentor other data scientists, and raise modeling and experimentation standards.

Build production AI retrieval and knowledge systems for rare disease research at NIH. Model biomedical ontologies in PostgreSQL, develop semantic search, retrieval-augmented services, ranking, evaluation, and observability, and deliver user interfaces with Next.js, React, and TypeScript. Deploy and operate services in on-premises and HPC Kubernetes environments, including GPU inference. Collaborate with NIH staff, clinicians, and researchers, and contribute to scientific publications.

Build and operate agentic AI systems for rare disease research, including multi-turn workflows, structured and validated outputs, tool calling, prompt testing, evaluation suites, asynchronous execution, streaming, observability, and failure handling. Collaborate with NIH staff, clinicians, geneticists, researchers, and patient communities to translate needs into reliable data models and system behavior. Own components through deployment, establish AI engineering standards, and contribute to scientific manuscripts, abstracts, and conference posters.

Senior individual contributor responsible for leading pet/P&C insurance pricing model development (GLMs and ML), owning end-to-end projects, performing EDA and root-cause analysis, communicating results to stakeholders, and mentoring junior team members.

Develop and tune ML models, productionize and deploy strategies for ML systems, and align cross-functionally to communicate performance metrics.

Lead end-to-end machine learning and advanced analytics projects: frame problems, build and deploy predictive/prescriptive models, design ETL pipelines, create dashboards and A/B test metrics, and deliver actionable insights to business stakeholders to improve fleet, pricing, and ridesharing products.

Lead end-to-end development of fraud and risk ML systems: define problems, engineer features, build and evaluate models, collaborate with product and engineering, deploy with ML engineers, and monitor production performance to detect drift and trigger retraining.

As a Staff Data Scientist, you will lead initiatives to build and optimize machine learning models, collaborate across departments, and solve complex business problems using data.

As a Data Scientist, you will build predictive models, develop software tools, and analyze geoscientific data to support mineral exploration and discovery.

As a Data Scientist, you will develop predictive models, analyze geoscientific data, and collaborate with geoscientists to improve mineral exploration efforts.

Owns the end-to-end development of cybersecurity vulnerability and exploit prediction models, including problem framing, feature engineering, training, evaluation, deployment, calibration, monitoring, and drift detection. The role addresses extreme class imbalance, hierarchical modeling, cold-start customers, and uncertainty quantification. It also requires explaining model outputs to security executives, publishing methodologies and benchmarks, and partnering with engineering to deploy reliable production systems.

Provides biostatistical data science and analytics support for clinical development and evidence generation. Collaborates with biostatistics, data management, clinical development, and medical affairs teams; applies statistics, mathematics, AI, and innovative technologies to clinical trial and real-world data. Contributes to clinical trial design, statistical analysis plans, clinical study reports, publications, and protocol development while following ICH and FDA guidelines.

Own end-to-end data science for a priority vertical (starting with Insurance): frame business problems, build and validate models, partner with ML engineering for deployment, monitor live ROAS performance, and drive measurable revenue and lead quality improvements.

Lead end-to-end data science projects including predictive modeling, algorithm design, and data pipelines. Build campaign-focused models (turnout, partisanship), perform exploration and visualization, translate insights into memos/presentations, collaborate with engineering to productionize models, mentor junior data scientists, and prototype emerging AI solutions for product impact.

The Senior Data Scientist will lead innovative data science efforts, leveraging advanced analytics, visualization, and insights from complex datasets to boost productivity.

Lead predictive modeling and causal inference initiatives for clients, developing models from exploratory analysis through production deployment, monitoring, and retraining. Apply GLMs, econometric methods, uplift modeling, propensity methods, and deep-learning forecasting. Process large-scale data with SQL and Spark, build models in Python, improve production reliability, and communicate findings to technical and business stakeholders in a consulting environment.