Top Senior Project Manager Jobs in St. Louis, MO

One Month AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Insurance • Software
Leads complex, cross-functional business and technology projects from initiation through closeout in a regulated Insurtech environment. Manages scope, schedules, budgets, risks, dependencies, vendors, governance, stakeholder communication, implementation readiness, and organizational change. Partners with insurance, product, technology, data, finance, legal, compliance, and external teams while using Agile, Waterfall, and hybrid delivery methods.
Top Skills: MS Office
21 Days AgoSaved
In-Office or Remote
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Information Technology • Software
Senior Project Manager responsible for overseeing moderate to highly complex initiatives from discovery through closeout. Duties include budget and cost tracking, stakeholder and executive communication, meeting facilitation, risk and dependency management, action-item follow-up, and adapting to changing priorities. The role requires advanced Microsoft Project skills, strong financial project experience, emotional intelligence, negotiation ability, and enthusiasm for adopting AI tools. Work is remote or hybrid with in-person collaboration as needed.
Top Skills: Ai ToolsMicrosoft Project
11 Days AgoSaved
Remote
St. Louis, MO
125K-135K Annually
Senior level
125K-135K Annually
Senior level
Cloud • Consulting
Manages CMS’s Digital Quality Initiative projects across healthcare, technical, and organizational workstreams. Develops plans, roadmaps, dashboards, and executive reporting; coordinates FHIR interoperability and systems integration activities; manages risks, dependencies, decisions, and stakeholder communication; and supports Agile portfolio alignment, change management, organizational readiness, and adoption. The role facilitates collaboration among CMS leadership, technical teams, contractors, and business stakeholders throughout a complex, multi-year transformation.
Top Skills: AgileFhirHealthcare Data ExchangeLean Portfolio ManagementSafeSystems Integration
11 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Software
Leads complex, cross-functional marketing projects from planning through completion; establishes governance, manages scope, risks, issues, dependencies, and stakeholder accountability; facilitates collaboration and reporting; and improves PMO methodologies, templates, and processes using Asana and related tools.
Top Skills: AsanaProject Management Tools
One Month AgoSaved
Remote
St. Louis, MO
90K-135K Annually
Senior level
90K-135K Annually
Senior level
Consulting
Lead client-side delivery of a complex enterprise financial system implementation for a state housing finance agency. Responsibilities include project planning, governance, vendor oversight, risk and issue management, executive reporting, business process review, data migration, testing, training, cutover, go-live, stabilization, and stakeholder coordination. The role also supports business development, team capability development, ERP provider relationships, marketing, and state government consulting opportunities.
Top Skills: Collaboration ToolsData MigrationEnterprise SoftwareErp SystemsMicrosoft 365Presentation ToolsProject Planning ToolsReporting ToolsSystem IntegrationUser Acceptance Testing
12 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Biotech
Leads cross-functional product initiatives from ideation through launch and iteration. Responsibilities include project planning, scheduling, budgeting, resource allocation, risk management, stakeholder communication, quality assurance, documentation, and process improvement. Partners with product, engineering, design, marketing, and leadership teams to deliver high-quality products on time, within scope, and within budget.
Top Skills: AgileAsanaJIRAKanbanMicrosoft ProjectScrumTrello
One Month AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Insurance
Leads strategic finance and accounting projects from initiation through closure, including ERP and financial systems implementations, IFRS 17 initiatives, process improvements, regulatory programs, and reporting transformations. Responsibilities include project planning, budgeting, resource and stakeholder management, risk and change control, vendor oversight, KPI reporting, quality assurance, training, and benefits realization. The role partners with multinational Finance, Accounting, technology, and business leadership teams and requires English-Spanish bilingual communication.
Top Skills: AgileErpMs ProjectSystems Development Life Cycle (Sdlc)Workday Financials
One Month AgoSaved
In-Office or Remote
St. Louis, MO
Senior level
Senior level
Healthtech • Biotech • Pharmaceutical • Manufacturing
Manages multiple healthcare improvement initiatives across timelines, budgets, workstreams, risks, deliverables, and stakeholder relationships. Coordinates Medical Affairs, Legal, compliance, health systems, professional societies, research institutes, and other partners. Tracks spending and milestones, supports governance meetings, synthesizes performance data, maintains project dashboards and collaboration tools, conducts landscape analyses, and identifies process improvements. Requires healthcare systems knowledge, quality improvement exposure, and CRO or pharma project management experience.
Top Skills: ClaudeMicrosoft Copilot
One Month AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Information Technology
Manage end-to-end Oracle and CRM implementation projects, including planning, budgeting, scheduling, risk management, stakeholder communication, testing, and production support. Lead cross-functional teams, oversee application design and development, allocate resources, present status reports, and ensure delivery meets business requirements. The role requires Oracle functional expertise, Agile experience, project management skills, and strong communication abilities. Work is remote or client-site with travel potentially reaching 75%.
Top Skills: AgileCRMItilMicrosoft Office SuiteOracleOracle CloudOracle CxOracle EpmOracle ErpOracle HcmOracle ScmSalesforce
Reposted 12 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Information Technology • Consulting
Lead Oracle Cloud EPM implementation projects from initiation through closure, managing scope, schedules, budgets, risks, quality, resources, stakeholders, and escalations. Build and guide cross-functional teams, oversee deliverables, maintain budget tracking, apply Agile and Scrum practices, and ensure successful client outcomes through strong communication, change management, and technical project leadership.
Top Skills: AgileJIRAMicrosoft ProjectOracle Cloud EpmScrumSmartsheetTrello
13 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Legal Tech
Leads multiple complex eDiscovery projects from planning through delivery, serving as the primary client contact. Manages schedules, budgets, resources, workflows, reporting, quality standards, and project communications. Provides consultative guidance on data collection, processing, review, analytics, and production. Supervises and mentors project teams, mitigates operational risks, supports client relationships, and contributes to business development.
Top Skills: Relativity
14 Days AgoSaved
Remote
St. Louis, MO
138K-180K Annually
Senior level
138K-180K Annually
Senior level
Healthtech
Leads complex DevOps and cloud infrastructure initiatives from planning through implementation. Coordinates engineering teams and technical workstreams, manages dependencies, risks, schedules, and security requirements, and drives CI/CD, infrastructure automation, cloud migrations, platform improvements, and continuous improvement. Develops dashboards and executive reporting while serving as the project-management interface across DevOps, engineering, security, QA, IT, product, and operations teams.
Top Skills: AgileArmAWSAzure DevopsAzure MonitorBicepCloudFormationConfluenceDastDatadogDevsecopsDockerGitGitGithub ActionsGitlabGitlab Ci/CdGCPGrafanaJenkinsJIRAKubernetesAzurePrometheusSastScrumSplunkTerraform
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Reposted 14 Days AgoSaved
Remote
St. Louis, MO
138K-180K Annually
Senior level
138K-180K Annually
Senior level
Healthtech
Leads technical medical device projects from planning through launch and post-implementation. Responsibilities include project scoping, scheduling, budgeting, risk management, design-control release planning, Scrum facilitation, cross-functional coordination, technical discussions, testing support, regulatory compliance, production release monitoring, and process improvement.
Top Skills: Aha!Atlassian JiraAWSConfluenceEmbedded SystemsIec 14971Iec 62304Iec 62366JamaLinuxMicrosoft Office SuiteMicrosoft ProjectUnixVisioWindows
14 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Software
Leads complex enterprise SaaS implementations for customers, managing project scope, budgets, timelines, resources, risks, dependencies, and governance. Partners with customers and cross-functional teams to gather requirements, guide solution design, support QA, resolve issues, and ensure successful delivery. Acts as a solution consultant, manages executive communications, identifies expansion opportunities, improves implementation methodology, and mentors project managers.
Top Skills: CertiniaFinancialforceSaaSSalesforce
14 Days AgoSaved
Remote
St. Louis, MO
149K-175K Annually
Senior level
149K-175K Annually
Senior level
Real Estate
Provides portfolio-level oversight of project controls, establishes governance and delivery frameworks, advises clients, leads staffing and resourcing decisions, mentors project controls managers and senior staff, and improves internal tools and processes. Requires advanced cost and schedule management expertise, strong client consulting and communication skills, and experience in construction, life sciences, data centers, industrial, or related technical fields.
14 Days AgoSaved
Remote
St. Louis, MO
128K-150K Annually
Senior level
128K-150K Annually
Senior level
Real Estate
Leads engineering and construction-related projects across client accounts, property portfolios, or large facilities. Manages budgets, timelines, reports, design reviews, consultants, contractors, invoices, change orders, and client presentations. Supervises project managers, space planners, and CAD operators; supports hiring, development, performance management, compliance, and organizational goals. Requires strong client communication, leadership, consultation, and technical proficiency.
Reposted 14 Days AgoSaved
Remote
St. Louis, MO
112K-164K Annually
Senior level
112K-164K Annually
Senior level
Healthtech • Manufacturing
Leads IT projects from initiation through closure, managing plans, deliverables, budgets, timelines, risks, issues, communications, and cross-functional teams. Establishes and improves project management methodology, PMO processes, governance, reporting, KPIs, resource planning, demand management, and project roadmaps. Partners with business leaders to align technology initiatives with organizational goals and expected benefits while ensuring compliance with quality, safety, security, environmental, and regulatory requirements.
Top Skills: ErpItsmMS OfficeMicrosoft ProjectMicrosoft Project ServerMicrosoft VisioSdlc
14 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Cybersecurity
Plans, schedules, organizes, and directs technical projects involving application engineering, field installation, and startup. Ensures projects meet budget, schedule, cash flow, safety, quality, and customer satisfaction goals. Serves as the primary customer interface, provides technical troubleshooting, and leads coaching, mentoring, staff development, and supervisory activities.
Top Skills: Building Automation SystemsElectronic Security SystemsFire Alarm SystemsIt NetworkingExcelMicrosoft OutlookMicrosoft PowerpointMicrosoft ProjectMicrosoft WordProgramming
14 Days AgoSaved
Remote
St. Louis, MO
180K-200K Annually
Senior level
180K-200K Annually
Senior level
Artificial Intelligence • Healthtech • Information Technology • Software
Own the master campaign calendar and coordinate customer campaign launches across engineering, deployment, clinical, QA, compliance, and data teams. Translate customer and clinical needs into precise technical requirements, manage approvals and change control, monitor launch readiness and risks, and maintain repeatable intake, documentation, and runbook processes. Track delivery metrics and improve tools and workflows for managing multiple concurrent healthcare campaigns.
Top Skills: Agentic AiAsanaJIRALinearSmartsheetVoice Ai Platforms
14 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Energy • Manufacturing • Solar • Renewable Energy
Own the full life cycle of Software and Controls Solutions projects, including planning, execution, monitoring, reporting, control, and closure. Lead internal and external teams, serve as the primary customer contact, ensure successful delivery and customer satisfaction, and support business growth and objectives in Korea.
One Month AgoSaved
In-Office
St. Louis, MO
Senior level
Senior level
Greentech • Energy • Industrial
Manages the full lifecycle of engineering and controls installation projects, including scope, budgets, schedules, resources, vendors, subcontractors, client communications, reporting, and closeout. Supervises project managers and technical staff, supports proposals and business development, coordinates material delivery, and ensures projects meet schedule, budget, quality, and client expectations. The role requires substantial travel to job sites and offices.
Top Skills: Erp
Reposted 15 Days AgoSaved
In-Office or Remote
St. Louis, MO
92K-203K Annually
Senior level
92K-203K Annually
Senior level
Information Technology
Lead delivery and technical direction for data solutions: define scope, anchor proofs-of-concept, provide solution architecture, integrate third-party services, manage timelines and budgets, ensure customer satisfaction, mentor teams, support sales and proposals, and run PMO practices across large multi-team engagements.
Top Skills: AgileData & AnalyticsScrum
15 Days AgoSaved
Remote
St. Louis, MO
101K-127K Annually
Senior level
101K-127K Annually
Senior level
Healthtech • Pharmaceutical
Leads multiple complex enterprise projects from business case development through implementation, managing scope, schedules, budgets, risks, dependencies, communications, stakeholders, and change requests. Partners with leadership and subject matter experts to deliver strategic initiatives involving IT and data elements. Applies Waterfall and Agile methodologies, supports portfolio governance, ensures testing and compliance, and mentors project managers and organizational leaders.
Top Skills: AgileAzure DevopsHipaaExcelMicrosoft PowerpointMicrosoft ProjectMicrosoft TeamsMicrosoft VisioMicrosoft WordPpm ProSmartsheetWaterfall
One Month AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Fintech • Payments • Software
Lead strategic, cross-functional projects for enterprise U.S. accounts, managing plans, milestones, dependencies, risks, governance, stakeholder alignment, executive reporting, and escalations. Coordinate Customer Success, Sales, Product, Operations, Finance, Legal, Risk, and Technology teams from planning through stabilization and post-project review. Drive accountability and decision-making without direct authority while ensuring customer and business objectives remain aligned.
Top Skills: DashboardsPayment Orchestration PlatformsProject Planning Tools
18 Days AgoSaved
Remote
St. Louis, MO
110K-140K Annually
Senior level
110K-140K Annually
Senior level
Design
Leads bridge and structural transportation projects from planning through construction support. Manages scope, schedules, budgets, staffing, quality, contracts, multidisciplinary teams, and technical deliverables. Provides bridge design and structural engineering leadership, coordinates with clients and transportation agencies, mentors staff, supports proposals and business development, and grows the firm’s Massachusetts and New England bridge practice.
Top Skills: AashtoMassdotMbta
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