Top Senior Project Manager Jobs in St. Louis, MO

Reposted 12 Days AgoSaved
Remote
St. Louis, MO
126K-173K Annually
Senior level
126K-173K Annually
Senior level
Healthtech • Pharmaceutical • Manufacturing
Leads cross-functional federal healthcare projects from planning through implementation, managing scope, budget, resources, milestones, stakeholders, partner relationships, and government customers. Supports revenue cycle, clinician solutions, procurement initiatives, and proposal development for future federal awards. The role is remote, requires a T3 Public Trust background check, and may involve up to 25% domestic travel.
Top Skills: 3M 360 Encompass
Reposted 13 Days AgoSaved
Remote
St. Louis, MO
95K-125K Annually
Senior level
95K-125K Annually
Senior level
Digital Media
Leads complex client-facing integrations between background screening platforms and ATS, HR technology, recruiting technology, and HRIS systems. Manages project scope, requirements, timelines, governance, risks, resources, testing, deployment, stabilization, and closure. Translates business needs into technical requirements, coordinates cross-functional teams, communicates with enterprise clients, and drives continuous improvement and standardized delivery practices.
Top Skills: APIsApplicant Tracking Systems (Ats)Data ExchangeHrisSaas PlatformsSoftware Development LifecycleSystem Integrations
14 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Biotech • Pharmaceutical
Plans and executes HR, employee engagement, company-wide meeting, leadership development, facilities, onboarding, and executive support initiatives. Manages project plans, timelines, budgets, vendors, communications, merchandise inventory, and cross-functional stakeholders. Coordinates events, leadership sessions, onboarding materials, and external visibility opportunities while maintaining confidentiality, organization, and operational efficiency. The role is predominantly remote but requires Philadelphia-area attendance and business-related travel.
Top Skills: Ai-Enabled ToolsCollaboration PlatformsMS OfficeMicrosoft OutlookMicrosoft SharepointMicrosoft TeamsProject Tracking Tools
14 Days AgoSaved
Remote
St. Louis, MO
100K-140K Annually
Senior level
100K-140K Annually
Senior level
Information Technology • Internet of Things • Software • Virtual Reality
Lead multiple customer-facing software implementation projects for manufacturing clients, managing scope, schedules, budgets, risks, resources, vendors, stakeholders, and delivery quality. Lead multidisciplinary consulting teams and collaborate with Customer Success, R&D, Workforce Management, and Technical Support. Apply Agile, Waterfall, and Scrum methodologies while overseeing ALM and PLM deployments. Responsibilities include project planning, status communication, escalation management, change control, and ensuring projects deliver measurable customer value.
Top Skills: AgileAlmMicrosoft Office SuitePlmProject Management SoftwareScrumWaterfall
14 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Greentech • Other • Biotech • Consulting • Energy
Leads multiple complex, cross-functional projects from requirements gathering through completion, managing scope, schedules, resources, budgets, risks, issues, changes, and deliverables. Communicates project status to stakeholders, tracks costs and progress, improves project management processes, and mentors project team members. Requires strong organizational, communication, and project implementation skills, plus experience with distributed teams and Dynamics 365 or an equivalent ERP system.
Top Skills: ErpMicrosoft Dynamics 365MS Office
15 Days AgoSaved
Remote
St. Louis, MO
163K-163K Annually
Senior level
163K-163K Annually
Senior level
Industrial • Manufacturing
Lead major $2–20 million manufacturing capital projects from concept through commissioning and handover. Manage project charters, budgets, schedules, risks, procurement, technical specifications, contractors, vendors, compliance, and documentation. Partner with operations, R&D, supply chain, and finance on capital planning, report to senior leadership, supervise team members, and drive continuous improvement. Ensure projects meet engineering, GMP, FDA, ISO, environmental, safety, validation, and sustainability requirements.
Top Skills: AutocadMs ProjectPrimavera
15 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Insurance
Owns end-to-end delivery of integrated marketing projects across multiple business-unit pods. Responsibilities include managing timelines, milestones, stakeholder communications, cross-functional coordination, project plans, dependencies, risks, capacity, and delivery reporting. The role partners with marketing, creative, production, and channel teams while maintaining visibility into portfolio health and adapting processes as the organization scales.
Top Skills: AsanaSarbanes-OxleyWorkfront
15 Days AgoSaved
Remote
St. Louis, MO
106K-173K Annually
Senior level
106K-173K Annually
Senior level
Information Technology • Consulting
Provides executive, sales, and strategic project support to the EVP of Global Client Services. Responsibilities include managing calendars, confidential communications, client and stakeholder relationships, sales pipelines, Salesforce reports, dashboards, events, meetings, travel, presentations, and action-item follow-up. The role coordinates complex initiatives, improves workflows, supports executive decision-making, and manages high-stakes timelines while exercising discretion and independent judgment.
Top Skills: EmprisingiOSOffice 365OutlookPowerPointSalesforceSharepointSmartsheetZoom
15 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Healthtech • Pharmaceutical • Manufacturing
Manages business improvement initiatives across Telix, coordinating workstreams, timelines, risks, dependencies, stakeholders, and governance. Conducts analysis and research, prepares dashboards and decision-support materials, facilitates cross-functional meetings, documents process changes, and supports operational improvements. The role requires independent execution, structured problem-solving, and collaboration in a fast-paced, matrixed pharmaceutical environment.
Top Skills: ExcelMS OfficeMicrosoft Powerpoint
Reposted 25 Days AgoSaved
In-Office or Remote
St. Louis, MO
Senior level
Senior level
Healthtech
Lead planning, execution, and delivery of large to extra-large projects. Define scope, manage resources, budgets, risks, stakeholders, and quality. Produce status reports and documentation, mentor junior PMs, and ensure projects meet timelines, budgets, and quality standards.
Top Skills: AsanaJIRAMs Project
18 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Healthtech • Information Technology • Consulting
Manage federal healthcare projects for a VHA client, including planning, scheduling, risk mitigation, leadership reporting, deliverable tracking, stakeholder coordination, executive briefings, strategic recommendations, and project communications. The role requires managing concurrent initiatives, facilitating working sessions, documenting workflows and business rules, and collaborating with multidisciplinary teams and senior client leadership.
Top Skills: Electronic Health Record (Ehr) SolutionsJIRAExcelMicrosoft PowerpointMicrosoft TeamsMicrosoft WordSharepoint
18 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Software
Manages strategic customer deployments, enterprise rollouts, and executive engagements while improving Customer Success processes and operations. Leads cross-functional initiatives, automates manual workflows, launches new programs, maintains playbooks, tracks project dependencies, measures outcomes, and communicates status to stakeholders. Partners with Customer Success, Sales, Product, Engineering, Support, Marketing, Finance, Solution Architects, and TAMs to improve customer delivery and organizational scalability.
Top Skills: Ai ModelsAsanaCybersecurityJIRAMonday.ComNotionSalesforceSlackZendesk
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18 Days AgoSaved
Remote
St. Louis, MO
116K-167K Annually
Senior level
116K-167K Annually
Senior level
Healthtech • Telehealth
Leads delivery of large-scale, complex projects and programs within approved budget, schedule, scope, and quality standards. Oversees project teams, applies standardized methodologies, mentors internal and third-party resources, manages daily activities, evaluates risks and change requests, recommends solutions, reports program status, and implements stakeholder communication plans.
19 Days AgoSaved
Remote
St. Louis, MO
87K-266K Annually
Senior level
87K-266K Annually
Senior level
Software
Manages Salesforce, CRM, and AI implementation projects for enterprise clients. Responsibilities include overseeing scope, schedules, financials, requirements, user stories, stakeholder communications, UAT, training, and delivery quality. The role serves as a client-facing project lead and Agile Scrum Master, coordinating architects and consultants through the software development lifecycle while tracking business outcomes and facilitating successful cloud-based solution implementations.
Top Skills: AgentforceAgileAmazon ConnectAWSSales CloudSalesforceSalesforce EinsteinSalesforce PlatformScrumSdlcService CloudService Cloud Voice
19 Days AgoSaved
Remote
St. Louis, MO
87K-266K Annually
Senior level
87K-266K Annually
Senior level
Software
Leads end-to-end delivery of AWS and Amazon Connect contact center, conversational AI, and agentic solutions. Responsibilities include managing scope, schedules, budgets, risks, dependencies, requirements, user stories, UAT, cutover, and post-launch support. The role serves as the primary client contact, facilitates stakeholder meetings, coordinates distributed technical and consulting teams, supports training and presentations, and guides Agile Scrum and SDLC processes.
Top Skills: AgileAmazon ConnectAmazon Web Services (Aws)Contact Center As A Service (Ccaas)Conversational AiDevOpsGenerative AiIvrJIRASalesforce AgentforceSalesforce EinsteinSalesforce Service Cloud VoiceScrumSmartsheet
6 Days AgoSaved
In-Office
St. Louis, MO
Senior level
Senior level
Agency • Marketing Tech • Design • App development
Supports industrial and infrastructure projects by coordinating multidisciplinary teams, schedules, budgets, deliverables, risks, documentation, and client relationships. The role contributes to site development, master planning, logistics, port, terminal, and intermodal assignments, using Primavera P6 for scheduling and project controls. It also supports proposals, scope development, feasibility analysis, process improvements, and progression toward broader project leadership.
Top Skills: Microsoft Office SuitePrimavera P6
7 Days AgoSaved
In-Office
St. Louis, MO
Senior level
Senior level
Manages complex industrial hygiene and safety projects, including scheduling technicians, coordinating equipment and laboratory work, overseeing technical reports, supporting clients, and ensuring timely project delivery. Provides technical assistance, performs field assessments and audits, develops safety programs, mentors Health & Safety Technicians, maintains professional certifications, and uses Navision for project management.
Top Skills: Navision
26 Days AgoSaved
Remote or Hybrid
St. Louis, MO
141K-153K Annually
Senior level
141K-153K Annually
Senior level
Healthtech • Information Technology • Security • Software • Cybersecurity
Leads complex enterprise IT solution deployments for healthcare clients, managing project plans, budgets, schedules, staffing, risks, vendors, and client relationships. Coordinates internal and external teams, tracks project progress and deliverables, communicates with leadership, supports SOW and budget estimation, resolves issues, and contributes to professional services project management methodologies.
Top Skills: FinancialforceExcelMicrosoft ProjectOpenairSalesforce
21 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Healthtech
Drive project, release, and roadmap delivery for product and development teams using Agile and traditional project management. Manage scope, schedules, resources, capacity, risks, dependencies, vendors, compliance, and stakeholder decisions. Maintain accurate planning and delivery data in Wrike, Agility, Smartsheet, and Domo. Use analytics and approved AI tools to forecast capacity, identify risks, and improve delivery, while validating AI outputs, protecting sensitive information, and retaining accountability for decisions.
Top Skills: Agentic Ai ToolsAgile/ScrumAgilityAi-Enabled ToolsDomoMS OfficeSmartsheetSoftware Development LifecycleWrike
Reposted 21 Days AgoSaved
Remote
St. Louis, MO
133K-181K Annually
Senior level
133K-181K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Leads large-scale Oracle Cloud Infrastructure migration programs, managing schedules, budgets, risks, dependencies, governance, vendors, stakeholders, and cloud delivery teams. Oversees migration planning and execution for applications, databases, and infrastructure; drives change management, documentation, training, compliance, cost optimization, quality, and operational reporting. The role also supports cloud adoption, partner coordination, and predictable cutovers across multiple initiatives.
Top Skills: AgileAnsibleDevOpsDevsecopsDockerKubernetesOracle Cloud Infrastructure (Oci)
26 Days AgoSaved
Remote or Hybrid
St. Louis, MO
117K-158K Annually
Senior level
117K-158K Annually
Senior level
Cloud • Fintech • Software • Business Intelligence • Consulting • Financial Services
Leads complex, multi-workstream client projects and portfolios, managing scope, schedules, budgets, risks, resources, governance, and engagement economics. The role develops delivery methodologies, dashboards, toolkits, and executive reporting; optimizes PSA/PPM tools; oversees capacity planning and portfolio prioritization; and aligns SDLC, change management, access controls, and governance frameworks. Candidates must have substantial project management experience, professional services experience, financial and resource management expertise, and willingness to travel approximately 15%.
Top Skills: AdaptiveCobitErpGaapItilMavenlinkOpenairPlanviewPsa/PpmSdlcSmartsheet
21 Days AgoSaved
Remote
St. Louis, MO
140K-190K Annually
Senior level
140K-190K Annually
Senior level
Cloud • Fintech • Other • Software
Manage multiple customer SaaS implementation projects from planning through closure. Responsibilities include controlling scope, schedules, budgets, resources, risks, and communication; coordinating cross-functional teams; managing customer expectations; maintaining project documentation; and reporting progress to leadership. The role requires SaaS deployment experience, strong stakeholder management, analytical decision-making, and familiarity with data integration and enterprise IT environments.
Top Skills: Data IntegrationSaaS
Reposted 8 Days AgoSaved
In-Office
St. Louis, MO
Senior level
Senior level
Consulting
Lead cross-functional IT projects from planning through delivery, ensuring scope, budget, schedule, vendor and resource management. Establish stakeholder communications, track risks and issues, and maintain relationships with executives, managing principals, and vendors to meet EPMO standards.
Top Skills: CsmPmp
22 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Pharmaceutical
Leads end-to-end customer onboarding and implementation programs, translating customer goals into project plans, milestones, dependencies, risks, and success metrics. Coordinates Sales, Product, Engineering, Support, Customer Success, trainers, and subject-matter experts without performing hands-on technical implementation or training. Establishes scalable operational frameworks, manages cross-functional accountability, oversees technical readiness, tracks adoption, facilitates stakeholder communications, and ensures customers are prepared for go-live.
Top Skills: Data PlatformsGantt ChartsMachine LearningSaaSSystem Integrations
Reposted One Month AgoSaved
In-Office
St. Louis, MO
70K-90K Annually
Senior level
70K-90K Annually
Senior level
Information Technology • Security
Manages security and access control installation and maintenance projects from concept through completion. Leads technicians, project engineers, contractors, and customer relationships while overseeing scheduling, job coordination, inventory, labor efficiency, financial performance, safety, compliance, and customer satisfaction. Provides technical guidance, supports operational excellence, and collaborates with sales, marketing, and accounting. The role requires local and occasional overnight travel, blueprint interpretation, job estimating, and project cost management.
Top Skills: Blueprint ReadingElectrical EngineeringElectronicsInformation TechnologySecurity And Access Control Systems
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