Top Senior Product Manager Jobs in St. Louis, MO

Reposted 27 Days AgoSaved
Remote
St. Louis, MO
110K-221K Annually
Senior level
110K-221K Annually
Senior level
Blockchain • Financial Services • Cryptocurrency • Web3
Lead Consumer Trading product initiatives for Krakendesigning features, prototyping with AI tools, defining requirements, running UAT, collaborating with stakeholders (Finance, Ops), and driving data-driven experimentation and product proposals to engage consumers.
Top Skills: Claude CodeCursorData Visualization ToolsSQL
Reposted 27 Days AgoSaved
Remote
St. Louis, MO
168K-231K Annually
Senior level
168K-231K Annually
Senior level
AdTech • Marketing Tech
Lead strategy, roadmap, and delivery for an in-house creative production and management product spanning video/CTV, AI-generated content, and multi-channel creative integrations. Drive 0->1 initiatives, define success metrics, collaborate with Engineering, Data Science, Design, and Creative Studio, and support customer-facing teams to launch, iterate, and scale creative tooling and partner integrations.
Top Skills: Ai/MlAPIsAudioCtvDisplay AdsDoohGenerative AiNative AdsProgrammatic AdvertisingVideo
Reposted 27 Days AgoSaved
Remote
St. Louis, MO
171K-207K Annually
Senior level
171K-207K Annually
Senior level
Fintech • HR Tech • Social Impact • Software • Financial Services
Lead product strategy and roadmap for a dedicated engineering team in the retirement-fintech platform. Define outcomes, measure business impact, prototype rapidly (using AI), partner across design, engineering, operations, revenue, and compliance, and use data to validate decisions and deliver scalable, compliant products.
Top Skills: AIClaude CodeCodexFigma Make
Reposted 27 Days AgoSaved
Remote
St. Louis, MO
149K-192K Annually
Senior level
149K-192K Annually
Senior level
AdTech
Lead product strategy and technical design for privacy-safe, multi-party data clean room integrations and identity resolution. Drive cross-functional execution with Engineering, Data Science, Legal, and BD, commercialize a major product line, mentor PMs, resolve systemic API/data pipeline issues, and communicate initiatives to executives and external partners.
Top Skills: Ai/MlCSS3CypressData Clean RoomsDjangoFlaskGraphQLHTML5Identity ResolutionJavaJavaScriptJestJwtMySQLNode.jsOauthPostgresPrismaPythonReactReact Testing LibraryRedisRestSequelizeSpring BootSQLSQL ServerTypescript
Reposted 27 Days AgoSaved
Remote
St. Louis, MO
175K-195K Annually
Senior level
175K-195K Annually
Senior level
Software
Lead strategy and end-to-end delivery for a Predictive Procurement Platform. Define product roadmaps, engage customers, coordinate with engineering and commercial teams, prototype AI-driven features, and drive releases to improve procurement outcomes and customer efficiency.
Top Skills: ChatgptClaudeCodexExcelFigmaHubspotIntercomJIRAMiroNextjsPostgresPythonReactRuby On RailsSlackSnowflakeSQL
28 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Insurance
Lead product vision and roadmap for data and analytics products (ML, generative AI, data pipelines, BI). Translate business needs into developer-ready features, maintain backlog, collaborate with engineering and stakeholders, track KPIs, and drive adoption and continuous improvement.
Top Skills: AgileAzure DevopsBusiness IntelligenceData PipelinesGenerative AiMachine LearningReports And Dashboards
Reposted 29 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Machine Learning • Software
The Sr. Product Manager will oversee the transformation of pharmacy payment integrity through AI automation, design workflows, and collaborate with teams to enhance customer-facing analytics and operational processes.
Top Skills: Ai ArchitecturesApi IntegrationsBi PlatformsData PipelinesVoice Interfaces
Reposted 29 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Software • Cybersecurity
Lead cross-platform product design for enterprise users and admins: translate complex systems into intuitive experiences, own and scale a unified design system, run user research, produce end-to-end deliverables (wireframes, prototypes, specs), and collaborate closely with Product and Engineering.
Top Skills: Ai ToolsCSSFigmaHTMLReact
Reposted 29 Days AgoSaved
Remote
St. Louis, MO
7K-12K Annually
Senior level
7K-12K Annually
Senior level
Other • Retail
Manage the strategy and roadmap for Costing and Rebates capabilities, coordinating with Finance, Accounting, and tech teams to deliver solutions that enhance financial outcomes and operational efficiency.
Top Skills: Agile MethodologiesBusiness Information SystemsComputer ScienceOracle FusionWaterfall
Reposted 29 Days AgoSaved
Remote
St. Louis, MO
117K-178K Annually
Senior level
117K-178K Annually
Senior level
Biotech
The Senior Product Manager is responsible for product management and commercialization of immunoassays, developing strategies, analyzing market trends, and guiding cross-functional teams for product success.
Top Skills: ImmunoassaysMarketingProduct Management
Reposted 29 Days AgoSaved
Remote
St. Louis, MO
150K-210K Annually
Senior level
150K-210K Annually
Senior level
Artificial Intelligence • Software
The Senior Product Manager will define and execute strategy for data platform capabilities, ensuring data usability, leading cross-functional teams, and driving measurable business outcomes in healthcare settings.
Top Skills: APIsData PlatformsEhrFhirHl7X12
Reposted 29 Days AgoSaved
Remote
St. Louis, MO
129K-228K Annually
Senior level
129K-228K Annually
Senior level
Consumer Web • Fintech • Insurance
The Staff/Product Manager will enhance the digital consumer experience for life insurance, focusing on user onboarding and product conversion. They will combine data insights with creativity to drive product growth and enhance user satisfaction without much friction.
Top Skills: AmplitudeSQL
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Reposted 29 Days AgoSaved
Remote
St. Louis, MO
62K-183K Annually
Senior level
62K-183K Annually
Senior level
Healthtech
Lead product strategy and execution for DaVita's FinTech portfolio, partnering with teams to solve problems and deliver improvements in enterprise financial systems.
Top Skills: AnaplanCoupaOracleOracle EbsOracle FusionVertex
Reposted 29 Days AgoSaved
Remote
St. Louis, MO
180K-205K Annually
Senior level
180K-205K Annually
Senior level
Legal Tech • Software
Own product vision and roadmap for Depositions by Filevine. Define specs and user stories, collaborate with engineering and GTM, drive launches, ensure UX and adoption, use data and customer feedback, and support QA and go-to-market activities.
Top Skills: AgileAILeanLegal TechLoisSaaS
One Month AgoSaved
Easy Apply
Remote or Hybrid
St. Louis, MO
Easy Apply
116K-168K Annually
Senior level
116K-168K Annually
Senior level
Cloud • Information Technology
Lead commercialization of AI-enabled mainframe managed services by productizing platform capabilities, defining pricing and packaging, owning roadmap and lifecycle, aligning cross-functional stakeholders, and enabling sales to scale repeatable, profitable offers driven by automation and platform innovations (Telum/Spyre).
Top Skills: AIAiopsCicsDb2Devops ToolingIbm LinuxoneIbm ZMainframeObservabilitySpyreTelumZ/Os
Reposted One Month AgoSaved
Remote
St. Louis, MO
145K-160K Annually
Senior level
145K-160K Annually
Senior level
Logistics • Transportation • 3PL: Third Party Logistics
Lead connectivity product strategy and roadmap across EDI, APIs, RPA, and integration platforms. Assess current-state, streamline trading-partner onboarding, define KPIs, enable self-service onboarding with Engineering, build data-driven business cases, align cross-functional stakeholders, and modernize integration tooling for scalable, reliable connectivity.
Top Skills: APIsData MappingEdi (X12)EdifactIpaas (Integration Platforms)RpaTms
Reposted One Month AgoSaved
Remote
St. Louis, MO
250K-325K Annually
Senior level
250K-325K Annually
Senior level
Fintech • Information Technology • Payments
Own the Platform product end-to-end: prioritize and manage roadmap for infrastructure, security, AI infra, data/compliance, and internal tooling. Collaborate closely with engineers and designers to frame problems, run research, define requirements, and measure post-release impact. Operate in an async, documentation-first culture and influence stakeholders to drive technical decisions and ship complex systems.
One Month AgoSaved
Remote
St. Louis, MO
100K-126K Annually
Senior level
100K-126K Annually
Senior level
Financial Services
Lead customer-driven enhancements, fintech integrations, and implementation commitments across Alkami's digital banking platform. Translate business needs into functional and technical requirements, manage a portfolio of client commitments, and drive end-to-end delivery with customers, vendors, sales, and engineering. Remove blockers, accelerate decisions, and improve delivery processes to ensure successful production launches and customer outcomes.
Top Skills: APIsAuthentication ProvidersCheck Image ProvidersEdocsOauthOpenid ConnectRdcSAMLSso
One Month AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Fintech • Financial Services
Lead end-to-end money movement and payments platform work—bank rails, payroll card program, payouts, routing, and reconciliation. Build reusable payment services with clear APIs and SLAs, write detailed requirements, work embedded with engineering, run experiments and staged rollouts, own production incidents, and coordinate Finance, Legal, Payment Ops, and external partners to deliver resilient, auditable, scaled payment systems.
Top Skills: AchAPIsPush-To-CardRtpWires
Reposted One Month AgoSaved
Remote or Hybrid
St. Louis, MO
Senior level
Senior level
Fintech • Financial Services
Lead design and scaling of a unified fraud and risk platform. Own roadmap, fraud metrics, SQL-based analysis, A/B testing, real-time detection models, and cross-functional delivery to balance customer experience and risk mitigation.
Top Skills: A/B TestingAPIsArtificial IntelligenceBlockchainData PipelinesMachine LearningRiskifiedSardineSQL
Reposted One Month AgoSaved
Remote
St. Louis, MO
170K-210K Annually
Senior level
170K-210K Annually
Senior level
Information Technology • Software
The Senior Product Manager will own product objectives, collaborate with cross-functional teams, and leverage customer feedback for product enhancements in a remote work environment.
Top Skills: Developer ToolingProduct AnalyticsReact NativeSaaS
Reposted One Month AgoSaved
Remote
St. Louis, MO
200K-220K Annually
Senior level
200K-220K Annually
Senior level
Artificial Intelligence • Insurance • Software • Automation
Define and manage product vision for Assured’s claims platform, collaborate with stakeholders, utilize data-driven insights, and lead complex decision-making processes.
Top Skills: AnalyticsCustomer InsightsSoftware Development
Reposted One Month AgoSaved
Remote
St. Louis, MO
180K-200K Annually
Senior level
180K-200K Annually
Senior level
Fintech • HR Tech • Software • Financial Services
The Lead Product Manager at Benepass will own a key product area, drive strategy and execution, and collaborate with cross-functional teams to enhance employee engagement with benefits.
Reposted One Month AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Information Technology • Software • Automation
Own and ship developer-focused observability product features (alerts, APM, onboarding, connected investigations). Collaborate with engineers and power users to improve UX, reduce alert fatigue, speed root-cause workflows, and optimize telemetry onboarding and query performance.
Top Skills: ClickhouseKafkaKubernetesOpentelemetry
Reposted One Month AgoSaved
Remote
St. Louis, MO
170K-190K Annually
Senior level
170K-190K Annually
Senior level
Artificial Intelligence • Software
Own the product roadmap and rollout planning for documentation, in-app guidance, and automation. Lead AI and agent-platform initiatives, run continuous customer discovery, write PRDs, measure post-launch impact, and partner with design and engineering to ship and scale product features.
Top Skills: Agent PlatformsAIGenerative AiProduct Analytics
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