Top Senior Software Engineer Jobs in St. Louis, MO

Reposted 9 Days AgoSaved
Remote or Hybrid
St. Louis, MO
246K-339K Annually
Senior level
246K-339K Annually
Senior level
Artificial Intelligence • Fintech • Machine Learning • Natural Language Processing • Business Intelligence
The role involves building robust software solutions, mentoring engineers, analyzing business problems, and contributing to technical strategy in a collaborative environment.
Top Skills: ReactRuby On RailsTypescriptVue
Reposted 9 Days AgoSaved
Remote
St. Louis, MO
190K-275K Annually
Senior level
190K-275K Annually
Senior level
Artificial Intelligence • Fintech • Machine Learning • Software • Financial Services
The Staff Software Engineer will design, build, and maintain compliance systems for fraud prevention, managing KYC workflows and regulatory reporting. They will mentor engineers and drive technical strategy while collaborating with various stakeholders.
Top Skills: AmlAPIsCase Management SystemsGoKycRegulatory Reporting
Reposted 9 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Information Technology • Software • Analytics • Business Intelligence
The Lead Software Engineer will design and maintain scalable software solutions, provide technical guidance, mentor junior engineers, and ensure software quality while collaborating with cross-functional teams.
Top Skills: AngularAWSJavaJavaScriptMySQLTypescript
Reposted 9 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Healthtech
Design, implement, and optimize core frontend, backend, and model-integration components. Drive engineering direction, ship and scale LLM-powered applications, build robust APIs and streaming systems, establish CI/CD and instrumentation, and deliver production-grade agentic workflows with measurable reliability and performance.
Top Skills: Api DesignAWSAzureCi/CdGCPLarge Language Models (Llms)Node.jsReactStreamingTypescript
Reposted 9 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Software • Energy • Automation
The Senior Backend Engineer will design and build scalable cloud-native backend systems for real-time monitoring and automation in HVAC operations, owning the entire lifecycle of services and mentoring junior engineers.
Top Skills: AirflowAmbassadorAWSAws Sqs/SnsDockerFlinkGoKafkaKinesisKongKubernetesNoSQLPythonSparkSQL
Reposted 9 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Digital Media • Social Media • Software • Sports
As a Staff Backend Engineer at FloSports, you'll lead backend development initiatives, focusing on scalable distributed systems, authentication frameworks, and mentoring engineers while collaborating with product teams for technical solutions.
Top Skills: Aws (AuroraDockerDynamoDBFastifyJestKubernetesLambdaNestjsNode.jsNoSQLS3)SQLSupertestTypescriptVitest
Reposted 9 Days AgoSaved
Remote
St. Louis, MO
122K-167K Annually
Senior level
122K-167K Annually
Senior level
Healthtech
Own and deliver reliable, secure software in a regulated healthcare environment. Drive solutions from ambiguity to production, build automation to reduce developer toil, mentor engineers, champion AI-assisted coding, and optimize database performance and schemas.
Top Skills: .NetAdo.NetAi-Assisted CodingEntity FrameworkHibernateJavaJunitNunitOrm FrameworksPl/SqlPytestPythonRelational DatabasesSQLSqlalchemyT-SqlXunit
Reposted 9 Days AgoSaved
Remote
St. Louis, MO
169K-192K Annually
Senior level
169K-192K Annually
Senior level
Cybersecurity
The role involves owning product and platform work, designing and building backend services and APIs, and improving system performance. The engineer collaborates across teams, addresses production issues, and applies AI tools in development.
Top Skills: AWSDockerGCPGitlab Ci/CdGoGrafanaKafkaKubernetesPostgresPrometheusPythonRedisSQLTypescript
Reposted 9 Days AgoSaved
Remote
St. Louis, MO
140K-170K Annually
Senior level
140K-170K Annually
Senior level
Manufacturing
The role involves designing, developing, and maintaining iOS applications, driving technical architecture, and promoting knowledge sharing within the team.
Top Skills: Ci/CdGitGraphQLSwiftSwiftui
Reposted 9 Days AgoSaved
Remote
St. Louis, MO
140K-160K Annually
Senior level
140K-160K Annually
Senior level
Security • Software
The Principal Software Engineer will provide architectural guidance, mentor developers, manage risks, and ensure high-quality software production across various teams and product areas.
Top Skills: .NetAngularAzure DevopsC#GitAzurePostgresSQL Server
Reposted 9 Days AgoSaved
In-Office or Remote
St. Louis, MO
197K-232K Annually
Senior level
197K-232K Annually
Senior level
Big Data • Information Technology • Software • Database • Analytics • Infrastructure as a Service (IaaS) • Big Data Analytics
The Senior Software Engineer II will design and implement complex backend systems for a data streaming platform, lead technical projects, and mentor engineers in a cloud-native environment.
Top Skills: AWSAzureC/C++DockerGCPGoJavaKubernetesNoSQLPythonSQL
Reposted 9 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Edtech
Senior Software Engineers will develop AI-native products, write maintainable code, deploy applications, and collaborate across teams to enhance learning experiences.
Top Skills: Agentic Coding ToolsAWSC#C++Ec2Github ActionsJavaJavaScriptLambdaLinuxRdsTypescript
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Reposted 9 Days AgoSaved
Remote
St. Louis, MO
138K-244K Annually
Senior level
138K-244K Annually
Senior level
Healthtech
The Senior Software Engineer will design and develop backend systems and APIs, mentor other engineers, and resolve complex integration challenges in healthcare technology.
Top Skills: DockerGoJavaKubernetesMongoDBMySQLPostgresPythonRuby
Reposted 9 Days AgoSaved
Remote
St. Louis, MO
200K-200K Annually
Senior level
200K-200K Annually
Senior level
Cloud • Information Technology • Software • Infrastructure as a Service (IaaS)
As a Senior Software Engineer, you will build and operate Upbound Spaces, resolve issues in SaaS environments, develop features, support project lifecycles, manage Kubernetes services, and enhance operational tools.
Top Skills: GoGrafanaKubernetesOpentelemetryPrometheus
Reposted 9 Days AgoSaved
Remote
St. Louis, MO
165K-250K Annually
Senior level
165K-250K Annually
Senior level
Information Technology • Other • Social Media
The Senior Software Engineer will develop backend systems, mentor engineers, and collaborate with cross-functional teams while contributing to product features and roadmaps.
Top Skills: AWSDjangoGoGraphQLJvmKafkaKotlinPostgresPythonRedisSQL
Reposted 9 Days AgoSaved
Remote
St. Louis, MO
190K-281K Annually
Senior level
190K-281K Annually
Senior level
Kids + Family • Mobile
As a Staff Software Engineer AI-Native, you will build and evolve AI-native engineering workflows, design high-quality APIs, and collaborate with international teams to deliver reliable services while mentoring others.
Top Skills: Ai Coding AssistantsAWSJavaKafkaKafka StreamsSpring Boot
Reposted 9 Days AgoSaved
Remote
St. Louis, MO
180K-259K Annually
Senior level
180K-259K Annually
Senior level
Security • Cybersecurity
The Senior Software Engineer will lead projects in the Adaptive Classifications team, focusing on backend systems, distributed computing, and architecting AI-driven workflows, while mentoring junior team members and collaborating across teams.
Top Skills: AWSCeleryDjangoGoKafkaKubernetesMySQLPostgresPrometheusPythonReact
Reposted 9 Days AgoSaved
Remote
St. Louis, MO
150K-175K Annually
Senior level
150K-175K Annually
Senior level
Analytics
As a Senior Software Engineer at Upwave, you will build scalable backend systems, develop APIs, and engineer data pipelines while collaborating with product and data science teams.
Top Skills: AWSDynamoDBJavaJavaScriptKotlinKubernetesMySQLPythonReactRestful ApisTerraform
Reposted 9 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Information Technology • Security • Automation
As a Staff Software Engineer at Radiant Security, you'll build and optimize data platforms, ensuring scalable data ingestion and system performance while collaborating across teams.
Top Skills: Apache KafkaAWSAws KinesisAzureBigQueryDatadogDockerElasticsearchGCPGoGrafanaKubernetesMongoDBNode.jsPrestoPrometheusPythonRedshiftSnowflakeSQL
Reposted 9 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Internet of Things
The Senior Software Engineer will enhance development workflows, mentor team members, collaborate on code reviews, and analyze data trends in Firefox development.
Top Skills: AWSCircleCIDjangoDockerFastapiFlaskGCPGithub ActionsJavaScriptPythonRestSQL
Reposted 10 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Cloud • Information Technology • Software • Cybersecurity
Lead the design and implementation of APIs, develop data pipelines, and mentor teams on AI integration and Agile methodologies.
Top Skills: .NetAzureAzure DevopsDockerGitKubernetesNode.jsPysparkPythonSQL
Reposted 10 Days AgoSaved
Remote
St. Louis, MO
150K-200K Annually
Senior level
150K-200K Annually
Senior level
Marketing Tech • Mobile • Software
The role involves owning the email channel's infrastructure, developing frontend experiences, designing backend systems, and ensuring deliverability in a cloud-native environment.
Top Skills: AWSEmberGCPGoMySQLReact
Reposted 10 Days AgoSaved
Remote
St. Louis, MO
10-10 Annually
Senior level
10-10 Annually
Senior level
Artificial Intelligence • Financial Services
This role involves owning and evolving the backend platform for AI employees, mentoring engineers, optimizing system performance, and driving architectural decisions at Supernal.
Top Skills: CeleryDatadogDjangoDramatiqGCPHelmKedaKubernetesOpentelemetryPostgresPythonRabbitMQRedisTerraform
Reposted 10 Days AgoSaved
Remote
St. Louis, MO
170K-300K Annually
Senior level
170K-300K Annually
Senior level
Fintech • Software
Build and operate full-stack, production-ready systems: design and ship AI-native mortgage automation, integrate third-party lending APIs, and architect scalable AWS infrastructure and job processing. Mentor engineers and ensure security, observability, and high reliability.
Top Skills: ApolloAWSCloudFormationDockerEcsElasticacheElasticsearchExpressGraphQLKafkaLlmsNode.jsPostgresRdsReactTerraformTypescript
Reposted 10 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
eCommerce • Information Technology • Software
As a Senior Software Engineer, you'll design scalable backend architectures, implement and optimize backend services, develop front-end UI, and collaborate with global teams to deliver software solutions.
Top Skills: .NetAi-Driven ToolsAngularAzureC#Microsoft Sql Server
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