Top Senior Machine Learning Jobs in St. Louis, MO

Build and expand in-database ML model catalog: implement new model types, ensure framework parity with scikit-learn/Spark ML, optimize training and inference at petabyte scale, extend SQL-level linear algebra, and collaborate across teams to deliver correct, performant ML features and documentation.

Build and operate model validation, quantization, and safety systems for production ML. Develop pipelines for security scanning, optimization (quantization/pruning), routing, prompt management, and evaluation frameworks measuring accuracy, performance, and safety across model lifecycles.

Lead design, development, and production deployment of ML models and GenAI/LLM solutions to optimize clinical trial workflows. Build scalable pipelines, monitoring, and CI/CD for robust production use. Collaborate cross-functionally, mentor junior engineers, and communicate technical results to technical and non-technical stakeholders.

The role involves building a large-scale data ingestion system using Python, web scraping, and data processing technologies to extract and classify data from diverse sources, and optimize data pipelines.

Lead and grow a multidisciplinary ML team focused on identification accuracy. Own roadmap, drive model training, evaluation, and deployment at scale, and partner cross-functionally to translate customer needs into technical priorities and measurable model performance outcomes.

Build and prototype supervised ML models to predict ad campaign delivery outcomes (reach, frequency, contention). Own feature engineering, evaluation frameworks, interpretability, and partner with ML engineers to deploy and monitor models at scale. Collaborate across product, engineering, and sales to drive adoption and measure lift versus simulation baselines.

Lead the design and delivery of a production-grade localization ML stack for autonomous vehicles: architect models for landmark-based localization across sensors, own data and evaluation pipelines, drive feature development to deployment, define failure modes and safety coverage, and mentor engineers while integrating cutting-edge multimodal and foundation-model techniques into robust, real-time localization systems.

Design, build, and operate production agentic AI systems on AWS Bedrock AgentCore using Strands/LangGraph. Implement tool integrations (MCP/Gateway), evaluation pipelines and LLM-as-judge CI gates, observability, cost/latency controls, and guardrails for agents operating on live dealer data.

Design, develop, implement, and monitor statistical and machine learning models to support credit risk, collections, servicing, marketing, and forecasting. Build data pipelines, translate business needs into analytical solutions, support model governance, testing, deployment, and ongoing performance monitoring, and communicate results to stakeholders.

Partner with customers to design and deliver production-ready AI/ML solutions, drive POC-to-production success, troubleshoot technical issues, inform product roadmap with customer feedback, and communicate outcomes to stakeholders.

The Senior Data Engineer will own the data strategy, managing sourcing, structuring, and optimizing multimodal data to enhance AI models and products.

As a Senior Machine Learning Engineer, you will develop and deploy AI-driven products to enhance clinical trials, collaborating with teams to improve patient care through scalable machine learning solutions.

Develop and tune ML models, productionize and deploy strategies for ML systems, and align cross-functionally to communicate performance metrics.

As a Staff Machine Learning Engineer, you will develop, productionize, and deploy ML models for clinical use, ensuring real-world effectiveness through hands-on coding and infrastructure building.

Lead end-to-end development of fraud and risk ML systems: define problems, engineer features, build and evaluate models, collaborate with product and engineering, deploy with ML engineers, and monitor production performance to detect drift and trigger retraining.

Lead AI/ML consulting engagements, build and deploy machine learning models and ETL pipelines, analyze large datasets, design data architectures, deliver visualizations, drive business development, and manage client-facing teams in high-stakes situations.

As a Staff Data Scientist, you will lead initiatives to build and optimize machine learning models, collaborate across departments, and solve complex business problems using data.

Develop and deploy machine learning solutions for autonomous truck applications: EDA, deep learning model development, embedded deployment, data ingestion/curation, analytics, visualization, technical leadership, and process improvement across manufacturing and business domains.

Build and design backend services, AI agents, and machine learning models. Collaborate cross-functionally to deliver AI features and maintain code quality.

Lead program delivery for engineering teams at Arine, optimizing internal processes and ensuring timely execution of technical programs while facilitating Agile methodologies.