Top Senior Machine Learning Jobs in St. Louis, MO

Leads the technical direction of an autonomous vehicle perception stack. Responsibilities include architecting scalable perception systems, developing scene detection and runtime activation, improving robustness against sensor degradation and adverse weather, integrating multimodal models, managing ML and data pipelines, monitoring field performance, leading testing and feature delivery, and mentoring engineers. Requires strong robotics, computer vision, machine learning, real-time systems, software architecture, and team leadership experience.

Lead ML technical strategy for Live Ads, designing and deploying forecasting, targeting, bidding, auction, and yield-optimization models. Build and evaluate large-scale production ML systems, create online/offline evaluation frameworks, partner with product to set objectives and trade-offs, and communicate results to stakeholders and leadership.

Lead ML initiatives to improve Sales productivity and automation: define roadmap, design and deploy production ML models and AI agents, build measurement pipelines with analytics engineers, iterate from performance and seller feedback, and act as senior technical partner across product, engineering, and Sales to drive measurable revenue impact.

Lead design and execution of a modernized, Python-native AI/ML platform for AIMS: define architecture, drive migration, build migration tooling, ensure scalability, observability, cost optimization, and reliability, prototype GenAI operational tooling, and set org-wide technical standards.

The role involves defining and refining Guidewire's AI narrative, crafting audience-specific messages, leading competitive positioning, and creating technical marketing assets to convey the value of AI-driven solutions in the P&C insurance sector.

The job involves building responsive web dashboards, advanced data visualizations, and analytics tools for unmanned aircraft systems, requiring a deep understanding of UI/UX design and data presentation.

Lead a team of ML engineers to design, build, and productionize LLM/GenAI and agentic systems (retrieval, tool use, orchestration). Collaborate cross-functionally with MLOps, product, and data science, review code, mentor engineers, run technical evaluations and proofs-of-concept, and ensure reliable, safe ML deployments for a large SaaS product.

Embed with strategic higher-education partners to design, build, and ship production AI and platform integrations (LLM/RAG, LTI) across Cengage products. Own end-to-end deployments, write production code, ensure compliance and accessibility, evaluate AI safety and outcomes, mentor FDEs, and translate field learnings into product roadmap contributions.

Lead design, development, and delivery of ML, DL, and Generative AI systems for production. Apply prescriptive analytics, optimization, recommendation, and reinforcement learning. Build and evaluate models, run experiments, develop prototypes, benchmark methods, and collaborate with business partners to translate data into actionable recommendations and influence strategy.

Design, develop, and deploy machine learning and deep learning models; build end-to-end ML pipelines including preprocessing, training, evaluation, and deployment; perform feature engineering on large datasets; deploy and monitor models on cloud platforms; collaborate with cross-functional teams to integrate AI solutions and retrain models as needed.

Design, build, and deploy production-grade generative AI applications: orchestrate multi-agent systems, implement advanced RAG with vector DBs, fine-tune and host LLMs, optimize GenAI workflows, and deliver scalable FastAPI-based backend services with Docker and monitoring.

Design, build, and scale production Generative AI systems: multi-agent orchestration, advanced RAG with vector databases, LLM integration and fine-tuning, scalable FastAPI backends, Dockerized deployment, monitoring, and GenAI optimization for latency, cost, and reliability.

Design, build, and deploy production-grade generative AI systems: multi-agent orchestration, advanced RAG with vector databases, integrate/swap LLMs, fine-tune models, optimize prompts and latency, and containerize services with monitoring and CI/CD.

Build and scale production Generative AI applications: design multi-agent systems and LangGraph workflows, implement advanced RAG with vector DBs, integrate and fine-tune LLMs, deploy FastAPI async services in Docker, and optimize GenAI performance, cost, and monitoring.

Design, implement, and own end-to-end scalable ML systems and MLOps lifecycle (deployment, monitoring, metrics). Optimize models and system performance, work with Java/Python and TF/PyTorch, use CI/CD, Terraform, Docker/Kubernetes, lead inter-team communication, document work, and meet deadlines.

Design, build, and deploy production-grade ML and AI systems end-to-end, combining classical ML, deep learning, and LLM/agentic integrations. Implement MLOps, monitoring, CI/CD, model serving, vector search/RAG pipelines, and scalable APIs; mentor engineers and drive engineering best practices.

Design, build, and deploy production Generative AI applications: orchestrate multi-agent workflows, implement advanced RAG with vector DBs, integrate and fine-tune LLMs, develop scalable FastAPI/async backends, containerize with Docker, and optimize GenAI systems for latency, cost, and reliability.

The Senior Analyst in Predictive Analytics and Machine Learning develops and maintains statistical models to support business decisions, monitors model performance, and collaborates with stakeholders across the company.

Build, deploy, and maintain production-grade ML systems across the full model lifecycle. Translate business goals into ML solutions, monitor model performance and drift, perform analyses and experiments, and collaborate with data engineers, product, and domain experts to improve risk assessment and underwriting outcomes.

Lead relevance evaluation and quality improvements by fine-tuning LLMs, building low-latency reranking and filtering systems, scaling LLM deployments, creating automated monitoring pipelines and agentic insights, and validating impact via A/B tests while collaborating with cross-functional teams.

Lead and grow a distributed ML engineering team that runs experiments, ships production models, and partners with Risk and platform teams. Balance research bets and delivery, enforce rigorous evaluation and reproducibility, mentor engineers, own roadmap trade-offs, and represent results to stakeholders while improving model performance and production reliability.

Build and maintain backend services and infrastructure for ML and generative AI features. Develop scalable, resilient, high-performance Python services (async frameworks, streaming), deploy to Kubernetes, integrate RAG and LLM orchestration, instrument LLM observability, and collaborate cross-functionally to deliver production-ready AI products.

The Senior Machine Learning Engineer will manage the full ML lifecycle, collaborating with teams to develop scalable systems that improve product decisions and empower monetization strategies.

Lead design, deployment, and monitoring of predictive models for credit risk, collections, and operations. Drive adoption of modern ML and MLOps, mentor data scientists, define strategic roadmap, advise senior leadership, and ensure model governance and regulatory compliance.

Lead the end-to-end machine learning lifecycle for AI products, managing data pipelines and model development to optimize performance and accuracy in production.