Top Senior Machine Learning Jobs in St. Louis, MO

As a Senior Machine Learning Engineer, you will develop and deploy AI-driven products to enhance clinical trials, collaborating with teams to improve patient care through scalable machine learning solutions.

The Staff ML Research Scientist will lead research in deep learning for drug discovery, develop innovative models, and integrate them into commercial software. Responsibilities include mentoring junior researchers and contributing to scientific publications.

The Specialist Solutions Architect will guide customers in architecting ML & AI applications, provide advanced technical support, and collaborate cross-functionally to enhance Databricks' AI offerings.

The role involves improving machine learning ranking models, implementing algorithms, and taking full ownership of machine learning systems within Quora's product.

Lead GoDaddy's three-year Generative AI and ML roadmap, architecting and scaling agentic and personalized AI solutions globally. Own end-to-end ML systems, enable rapid experimentation, ensure governance/compliance, and partner across product, engineering, and analytics. Mentor and grow high-performing teams and drive adoption of advanced AI techniques to improve customer experiences and business outcomes.

Develop and tune ML models, productionize and deploy strategies for ML systems, and align cross-functionally to communicate performance metrics.

As a Staff Machine Learning Engineer, you will develop, productionize, and deploy ML models for clinical use, ensuring real-world effectiveness through hands-on coding and infrastructure building.

Serve as an AI/ML-focused solution engineer for Healthcare & Life Sciences: provide technical guidance, design cloud data and lakehouse architectures on Snowflake, lead demos and proofs-of-concept, support sales cycles, collaborate with product and engineering, and communicate AI/ML value to technical and executive stakeholders.

The Staff Machine Learning Engineer will develop and maintain MLOps tools, optimize model performance, and collaborate on ML system architecture with a focus on enhancing developer experience.

Develop and deploy machine learning solutions for autonomous truck applications: EDA, deep learning model development, embedded deployment, data ingestion/curation, analytics, visualization, technical leadership, and process improvement across manufacturing and business domains.

As a Staff Data Scientist, you will lead initiatives to build and optimize machine learning models, collaborate across departments, and solve complex business problems using data.

Build and design backend services, AI agents, and machine learning models. Collaborate cross-functionally to deliver AI features and maintain code quality.

The Senior ML Data Scientist will develop machine learning models to detect fraud, manage the data science lifecycle, and collaborate with teams on strategies.

Lead design, training, fine-tuning, and deployment of ML and generative models (LLMs, diffusion). Build scalable MLOps pipelines, vectorization and data ingestion, integrate models into microservices for low-latency inference, implement evaluation/alignment/bias-mitigation, optimize models (quantization, distillation), and mentor engineers while influencing the AI product roadmap.

As a Senior Machine Learning Engineer at ZoomInfo, you will enhance core datasets through ML/NLP solutions, manage entity resolution tasks, and drive cross-functional impact by mentoring teams and collaborating on ML KPIs.

Develop and iterate deep learning models for protein-ligand co-folding and structure prediction, benchmark performance, integrate validated models into production drug-discovery pipelines, analyze structural and sequence data, communicate findings, and collaborate with multidisciplinary teams to scale research into products.

Design and operate production ML systems for large-scale streaming data, ensuring reliability and performance while collaborating with researchers to integrate models into distributed systems.

The role involves improving AI agent quality through designing experiments, maintaining evaluation infrastructure, optimizing LLM inference, and collaborating with product teams. Responsibilities include end-to-end ownership from research to deployment in a dedicated ML Engineer context.

Lead design, development, and productionization of advanced ML models and data pipelines. Drive architecture, experimentation, validation, and best practices while mentoring ML engineers and delivering scalable, business-driving AI solutions.

The Machine Learning Engineer will design and build systems that improve the AI shopping agent by using real user feedback, focusing on feedback loops and metrics to enhance user interactions and agent performance.

Lead design and delivery of scalable AI systems for autonomous threat detection and response. Build and productionize LLMs, graph reasoning engines, streaming feature pipelines, and orchestration frameworks. Own evaluation, reliability, and cross-functional collaboration while mentoring engineers and experimenting with RAG, tool-calling agents, and multi-modal models.

The Lead Machine Learning Scientist will develop and implement ML strategies to enhance marketing and product capabilities, identify opportunities for growth using data, lead core model development, and improve marketing spend efficiency through insights and experimentation.

Design, build, and deploy scalable ML models and pipelines to enhance a talent marketplace and GenAI solutions. Lead experimentation (A/B tests, statistical validation), improve production ML performance, ensure code and data quality, work with cross-functional teams, mentor junior engineers, and propose innovative AI-driven solutions aligned to business goals.

Design, build, and deploy production-grade AI/ML and LLM-based systems. Lead end-to-end ML lifecycle, implement RAG and embedding pipelines, establish MLOps best practices, mentor engineers, and collaborate with cross-functional teams to deliver scalable, responsible AI solutions.

The Machine Learning Engineer will develop software solutions, optimize data pipelines, and deploy machine learning models using cloud platforms and best practices.