Top Senior Cyber Security Jobs in San Diego, CA

Reposted 2 Days AgoSaved
Remote
San Diego, CA
86K-223K Annually
Senior level
86K-223K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Designs and implements cloud security solutions for Microsoft Azure and Microsoft 365 customers. Leads security architecture discussions, Zero Trust adoption, technical evaluations, implementation planning, troubleshooting, and enterprise security strategy. Advises executives and technical stakeholders on identity and access management, threat protection, cloud security, information protection, and secure-by-design architectures. Collaborates with Microsoft engineering, product, and security teams to remove blockers and orchestrates technical resources to deliver customer outcomes.
Top Skills: Azure Active DirectoryConditional AccessExtended Detection And Response (Xdr)Identity GovernanceIdentity ProtectionMicrosoft 365Microsoft 365 DefenderAzureMicrosoft Defender For CloudMicrosoft Endpoint ProtectionMicrosoft IntuneMicrosoft SentinelZero Trust
3 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Healthtech
Secure software and cloud environments through threat modeling, code review, vulnerability remediation, security automation, detection engineering, and attack simulations. The role partners closely with Engineering, manages Snyk and Docker Scout findings, integrates security into CI/CD, coordinates third-party penetration testing for SOC 2 and HITRUST, and helps define secure architecture for mobile, data lake, AI, and production cloud systems.
Top Skills: AIAptibleAWSCi/CdDastDocker ScoutGoMachine LearningMicrosoft 365Pentest-ToolsPythonSastSnykSoftware Bill Of Materials (Sbom)
3 Days AgoSaved
Remote
San Diego, CA
184K-357K Annually
Senior level
184K-357K Annually
Senior level
Artificial Intelligence • Computer Vision • Hardware • Robotics • Metaverse
Build and operate security controls, telemetry, detections, and enforcement for NVIDIA’s large-scale EDA compute, storage, and networking infrastructure across on-premises and multi-cloud environments. Investigate threats, respond to incidents, automate secure configurations and compliance evidence, threat-model infrastructure, and manage security technology lifecycles. The role requires hands-on Linux, networking, programming, infrastructure security, and collaboration with infrastructure and security teams.
Top Skills: CnappCompute ClustersCspmDpu/SmartnicEbpfEdr/XdrGoIamInfrastructure-As-CodeLinuxMulti-CloudNetworkingPolicy-As-CodePythonShellSIEMStorage
3 Days AgoSaved
Remote
San Diego, CA
159K-257K Annually
Senior level
159K-257K Annually
Senior level
Healthtech • Biotech • Pharmaceutical
Leads Lilly’s enterprise security posture and exposure management organization. Owns vulnerability management strategy, scanning architecture, application security integration, offensive security oversight, risk-based prioritization, remediation SLAs, exposure reporting, tooling, automation, vendors, budget, and executive accountability. The role requires deep hands-on cybersecurity expertise and experience leading leaders across enterprise-scale vulnerability management or security operations.
Top Skills: Agent-Based ScanningAttack Surface ManagementAuthenticated ScanningCloud SecurityCmdbDastData PipelinesOt SecuritySastSoftware Composition AnalysisTicketing SystemsVulnerability Scanning
3 Days AgoSaved
Remote
San Diego, CA
175K-200K Annually
Senior level
175K-200K Annually
Senior level
Fintech • Software
Designs and builds secure AWS infrastructure for a regulated SaaS platform. Responsibilities include cloud security architecture, IAM, networking, containers, encryption, logging, monitoring, automated guardrails, risk remediation, reference architectures, and engineering mentorship. The role partners with application security and infrastructure teams to secure AWS environments across design and production, supporting compliance for financial services customers.
Top Skills: Amazon EcsAmazon EksAmazon GuarddutyAmazon VpcAmazon Web Services (Aws)Aws CloudformationAws CloudhsmAws IamAws KmsAws Network FirewallAws OrganizationsAws Security HubAws WafCloudtrailIam Identity CenterKubernetesMicrosoft 365AzureSecurity GroupsService Control PoliciesTerraformVpc Flow LogsWiz
3 Days AgoSaved
Remote
San Diego, CA
175K-200K Annually
Senior level
175K-200K Annually
Senior level
Fintech • Software
Design and lead the application security program centered on Wiz. Automate security throughout the SDLC, including code, dependency, secrets, container, infrastructure-as-code, and release scanning. Establish threat modeling, secure design reviews, and guardrails for AI-assisted development. Improve developer adoption by delivering accurate findings within existing tools, while mentoring the AppSec team and partnering with cloud and AI security architects.
Top Skills: APIsAzure DevopsClaude CodeContainersCursorGitGithub CopilotGitlabOwasp Top 10Owasp Top 10 For Large Language Model ApplicationsPolicy As CodeWiz
3 Days AgoSaved
In-Office or Remote
San Diego, CA
192K-357K Annually
Senior level
192K-357K Annually
Senior level
Artificial Intelligence • Computer Vision • Hardware • Robotics • Metaverse
Conducts novel research in AI security and cybersecurity, focusing on protecting AI models, agents, systems, and infrastructure. Develops tools and processes to identify and remediate weaknesses, researches adversarial machine learning and generative AI security, publishes findings, and collaborates across teams to improve security practices.
Top Skills: Adversarial Machine LearningArtificial IntelligenceCybersecurityGenerative AiMachine LearningSecure Software Development
One Month AgoSaved
Easy Apply
Remote or Hybrid
San Diego, CA
Easy Apply
134K-168K Annually
Senior level
134K-168K Annually
Senior level
Cloud • Information Technology • Security • Software • Cybersecurity
Lead insider risk detection engineering and investigations using EDR/XDR, UEBA, SIEM, and SOAR tools. Refine detection rules, reduce alert noise, close coverage gaps, manage investigations, develop playbooks, document evidence, mentor analysts, and collaborate discreetly with HR, Legal, business leaders, and executives. The role also requires investigative workflow automation using Python or JavaScript and ownership of scalable security processes.
Top Skills: Ai/MlCertEdr/XdrJavaScriptNistNsaPythonSIEMSoarUebaZscaler Cyberrisk ProtectionZscaler Data ProtectionZscaler Zero Trust Networking
4 Days AgoSaved
Remote
San Diego, CA
97K-155K Annually
Senior level
97K-155K Annually
Senior level
Edtech
Implements and operates data security controls across cloud analytics platforms, databases, data lakes, storage, and pipelines. Responsibilities include encryption, key and secrets management, least-privilege access, data classification, masking, tokenization, database hardening, secure integrations, entitlement reviews, automation, telemetry, compliance evidence, threat modeling, documentation, and technical support. The role collaborates with security, data, governance, engineering, and IT teams while working remotely.
Top Skills: AbacAzure SqlCi/CdData Loss Prevention (Dlp)DatabricksInfrastructure As Code (Iac)AzureMicrosoft FabricRbacSQLSQL Server
4 Days AgoSaved
Remote
San Diego, CA
150K-170K Annually
Senior level
150K-170K Annually
Senior level
Consumer Web
Own Playlist’s technical GRC architecture across multiple compliance frameworks, including PCI DSS, SOC, ISO 27001, HITRUST, and NIST. Design unified control mappings, maintain the Master Control List, manage control and evidence lifecycles, automate evidence collection, and translate requirements into engineering guidance. Build AI-powered GRC workflows for risk quantification, vendor assessment, and compliance monitoring while partnering with Engineering, Legal, Finance, and auditors.
Top Skills: Amazon AuroraAmazon EventbridgeAmazon RdsAmazon S3AnecdotesAPIsAws LambdaAws Step FunctionsDrataGrc Automation ToolsHyperproofLlm PipelinesMulti-Agent SystemsOptroOscalRag ArchitecturesRelational DatabasesVanta
4 Days AgoSaved
In-Office or Remote
San Diego, CA
184K-357K Annually
Senior level
184K-357K Annually
Senior level
Artificial Intelligence • Computer Vision • Hardware • Robotics • Metaverse
Design and guide security architecture for NVIDIA networking firmware and embedded subsystems. Responsibilities include threat modeling, analyzing firmware and hardware interactions, defining lifecycle security features, translating threats into requirements, partnering with hardware architects, and driving secure firmware development practices such as memory-safe C, static analysis, and fuzzing. The role requires expertise in firmware security, authorization models, cryptography, secure boot, attestation, and embedded systems.
Top Skills: Applied CryptographyAsicsAttestationCCode SigningDevice DriversDmaEmbedded Network Operating SystemsEmbedded SystemsFirmware FuzzingFuse/Otp ProvisioningHardware Roots Of TrustMmioMpu/MmuPcieRbacSecure BootSecure EnclavesSocsStatic AnalysisThreat Modeling
4 Days AgoSaved
Remote
San Diego, CA
150K-170K Annually
Senior level
150K-170K Annually
Senior level
Artificial Intelligence • Beauty • Fitness • Software
Own Playlist’s technical GRC architecture, including a unified Master Control List, cross-framework mappings, control lifecycles, evidence requirements, and audit automation. Build scalable GRC tooling and AI-powered workflows for risk quantification, vendor assessments, evidence collection, and compliance monitoring. Partner with Security Engineering, Legal, Finance, and product teams to translate regulatory requirements into actionable controls and harmonize compliance across multiple brands.
Top Skills: Amazon AuroraAmazon EventbridgeAmazon RdsAmazon S3AnecdotesAPIsAws LambdaAws Step FunctionsDrataHitrustHyperproofIso 27001LlmsMulti-Agent SystemsNist 800-53Nist CsfOptroOscalPci DssRag ArchitecturesRelational DatabasesSoc 1 Type IiSoc 2Vanta
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4 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Healthtech • Software
Owns and strengthens the security posture of cloud-based SaaS and Microsoft 365 environments. Responsibilities include vulnerability management, incident response, cloud and endpoint hardening, identity and data protection, secure configuration, monitoring, compliance evidence, customer security reviews, and risk management aligned with HITRUST, HIPAA, NIST, and related frameworks.
Top Skills: Conditional AccessEntra IdMicrosoft 365AzureMicrosoft DefenderMicrosoft IntuneMicrosoft PurviewMicrosoft SentinelPowershellPython
Reposted 4 Days AgoSaved
Remote
San Diego, CA
70K-84K Annually
Senior level
70K-84K Annually
Senior level
Social Impact
Designs, implements, configures, and supports enterprise cybersecurity solutions across IAM, endpoint, network, email, application, cloud, and security awareness domains. Conducts vulnerability assessments, threat hunting, incident investigation, security tool tuning, policy development, and security architecture reviews. Serves as a security subject matter expert on technology projects, collaborates with an MSSP, provides incident escalation support, and maintains availability for critical security operations.
Top Skills: AtpAzureAzure Active DirectoryAzure SentinelAzure VmCisco FirewallsCisco Umbrella Dns SecurityContent FilteringEdrEmail Security GatewaysEndpoint SecurityIamIntuneMicrosoft DefenderNetwork FirewallsNetwork Security GroupsOffice 365SsoVirtualizationVMwareWindows ServerXdr
14 Days AgoSaved
In-Office
San Diego, CA
120K-150K Annually
Senior level
120K-150K Annually
Senior level
Information Technology
Supports cybersecurity governance and compliance across cloud and on-premises environments. Responsibilities include maintaining policies, validating security controls and vulnerability findings, preparing audit evidence, tracking remediation, conducting risk assessments, supporting access governance, and communicating security posture to leadership. The role also supports CMMC readiness, security awareness, incident documentation, and coordination with IT, Engineering, Program Management, and security leadership. An active Secret clearance must be obtained and maintained.
Top Skills: CismCisspCloud EnvironmentsCmmcComptia Security+Dcsa Security PackagesNispomNistOn-Premises EnvironmentsRmfVulnerability Scanning
15 Days AgoSaved
In-Office
San Diego, CA
111K-185K Annually
Senior level
111K-185K Annually
Senior level
Information Technology • Professional Services • Defense
Conducts information system security engineering for a Naval Information Warfare Center program, including defining security requirements and integrating controls into technology components. Supports system design reviews, cybersecurity assessments, and RMF activities across hardware and software development. Requires cybersecurity experience, IA certification, U.S. citizenship, and Top Secret/SCI clearance. Travel is approximately 20% for security assessments.
Top Skills: CybersecurityNessusRisk Management Framework (Rmf)Scap Compliance CheckerTenable Security Center
Reposted 6 Days AgoSaved
In-Office or Remote
San Diego, CA
175K-250K Annually
Senior level
175K-250K Annually
Senior level
Digital Media • Fintech • Information Technology • Machine Learning • Financial Services • Cybersecurity • Automation
Lead design, deployment, and scaling of enterprise DLP across cloud, endpoint, SaaS, and network with a focus on AI-driven automation. Build automated classification, remediation, and workflows, integrate DLP with SIEM/SOAR/identity/cloud, develop policies for regulatory compliance, mentor engineers, and present program insights to leadership.
Top Skills: Agent-Based DlpAi/MlAWSAzureCasbDlpDspmGCPIdentity PlatformsKqlPowershellPythonSIEMSoarSse
Reposted 6 Days AgoSaved
In-Office or Remote
San Diego, CA
135K-180K Annually
Senior level
135K-180K Annually
Senior level
Digital Media • Fintech • Information Technology • Machine Learning • Financial Services • Cybersecurity • Automation
Lead and own the enterprise SSPM program: implement and manage SSPM platform, onboard SaaS apps, tune controls, integrate with SIEM/SOAR/ITSM/identity, perform threat modeling and risk assessments, drive remediation, support compliance mapping, report metrics, and partner across cyber, IT, risk, and business teams to reduce data exposure and improve SaaS security posture.
Top Skills: APIsFederationGoogle WorkspaceItsmMicrosoft 365OauthOidcSalesforceServicenowSIEMSoarSspmWorkday
7 Days AgoSaved
Remote
San Diego, CA
120K-194K Annually
Senior level
120K-194K Annually
Senior level
Insurance
Own the strategy, roadmap, delivery, and lifecycle of enterprise data security products. Lead data governance, discovery, classification, DLP, access governance, compliance, and secure-by-design capabilities. Manage backlogs, Agile delivery, KPIs, stakeholder communication, and risk reduction outcomes while integrating AI to improve security workflows and productivity.
Top Skills: AgileAi/MlAPIsAWSAzureCi/CdCursorData Loss Prevention (Dlp)Data Security Posture Management (Dspm)DevsecopsGCPMicrosoft 365Microsoft CopilotOnedriveSaaSSharepoint
Reposted 7 Days AgoSaved
In-Office or Remote
San Diego, CA
143K-304K Annually
Senior level
143K-304K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Leads architecture and implementation of Microsoft Red Team visibility, telemetry, monitoring, detection, alerting, deconfliction, and operational security capabilities. Designs scalable services and data pipelines, maintains authoritative operational asset inventories, identifies systemic security gaps, and drives durable engineering solutions. Provides hands-on technical leadership, architecture reviews, debugging, incident response, mentorship, and cross-organizational influence while enabling authentic Red Team operations with strong defensive visibility and control.
Top Skills: AutomationCC#C++Cloud SecurityData PipelinesDetection EngineeringDistributed ServicesEndpoint SecurityIdentity SecurityJavaJavaScriptPythonSecurity Telemetry
7 Days AgoSaved
Remote
San Diego, CA
220K-240K Annually
Senior level
220K-240K Annually
Senior level
Security
Own corporate detection and response, incident response, endpoint security, identity and SaaS security, Google Workspace governance, and corporate-to-production monitoring. Build LLM-driven security triage with measured evaluation, automate enforcement through vendor APIs, improve detection fidelity, and partner with engineering to ship security improvements. Manage Mac fleet security, phishing-resistant authentication, access reviews, DLP, OAuth governance, and containment playbooks.
Top Skills: AndroidApps ScriptCloud IamDlpEdrGoGoogle WorkspaceIdpiOSLlmsmacOSMdmOauthOidcPythonSAMLSIEMTypescript
7 Days AgoSaved
Remote
San Diego, CA
75K-126K Annually
Senior level
75K-126K Annually
Senior level
Insurance
Engineer and maintain enterprise network security platforms across on-premises and cloud environments. Design firewall and network security solutions, troubleshoot complex connectivity and security issues, and automate infrastructure operations using scripting, APIs, Infrastructure as Code, configuration management, and CI/CD pipelines. Support platform upgrades, vulnerability remediation, monitoring integrations, validation processes, and modernization initiatives while collaborating with network, cloud, application, and security teams.
Top Skills: AnsibleAWSAzureAzure DevopsBashCi/CdDnsGitGithub ActionsGitlab Ci/CdInfrastructure As CodeJenkinsLoad BalancingNatNetwork SegmentationPalo Alto NetworksPanoramaPowershellPythonRest ApisTcp/IpVpn
One Month AgoSaved
Easy Apply
Remote or Hybrid
San Diego, CA
Easy Apply
135K-228K Annually
Senior level
135K-228K Annually
Senior level
Artificial Intelligence • Cloud • Computer Vision • Hardware • Internet of Things • Software
Monitor and analyze security events, lead incident response and employee investigations, conduct digital forensics, and communicate findings to technical, executive, legal, and compliance stakeholders. Build investigation scripts, runbooks, automated workflows, and security operations capabilities. Mentor engineers and support insider threat initiatives while collaborating across teams on cloud security and incident response.
Top Skills: AWSGCPLinuxmacOSPythonSIEMWindows
Reposted 7 Days AgoSaved
Remote
San Diego, CA
137K-183K Annually
Senior level
137K-183K Annually
Senior level
Internet of Things
Maintain and mature Mozilla's ISMS and support ISO 27001 and SOC 2 Type 2 audit programs. Author system descriptions and policies, manage risk treatment plans, track remediation, support internal audits, and partner with Engineering, Legal, Privacy, and Product to drive control ownership and audit readiness.
Top Skills: IsmsIso 27001Soc 2 Trust Services CriteriaSoc 2 Type 2
Reposted 7 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Internet of Things
Maintain and mature Mozilla's ISMS, support ISO 27001 and SOC 2 Type 2 audits, author compliance narratives, track remediation, lead policy program, scale compliance for products, and partner with cross-functional teams to drive control ownership and audit readiness.
Top Skills: IsmsIso 27001Soc 2Soc 2 Trust Services CriteriaStatement Of Applicability (Soa)
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