Top Remote Python Jobs in Washington, DC

As a Senior Software Engineer, you'll build AI-powered features, integrate LLMs, design scalable systems, mentor teammates, and collaborate to enhance user experiences.

Glean seeks a Solutions Architect to act as a primary technical advisor, guiding customers in implementing Glean's platform, integrating data sources, and providing support and training.

Lead efforts to maintain and uplift technology platforms and infrastructure. Oversee production operations and collaborate globally on system reliability and automation solutions.

The Senior Backend Engineer will design and build scalable cloud-native backend systems for real-time monitoring and automation in HVAC operations, owning the entire lifecycle of services and mentoring junior engineers.

The QA Engineer will analyze test requirements, automate testing, maintain frameworks, troubleshoot issues, and participate in design discussions, ensuring quality in a dynamic environment.

Implement and maintain AWS cloud standards, IaC patterns, and CI/CD automation to enable developer self-service. Support containerized workloads, monitoring, security/compliance, troubleshooting, documentation, and participate in on-call rotation to ensure reliable, cost-efficient cloud platform operations.

Lead and enhance developer experience through platform engineering, set technical direction, standardize CI/CD workflows, and ensure security compliance.

Design, implement, and maintain secure, highly available cloud database systems (AWS RDS/Aurora) for healthcare. Monitor performance, enforce security and compliance (HIPAA/HITECH/PCI DSS), automate with scripting/infra-as-code, develop backup/disaster recovery, troubleshoot issues, and collaborate with IT, development, and compliance teams.

Build and optimize on-device search algorithms and offline data delivery systems for mobile and automotive platforms. Implement tile compression and delta update pipelines, integrate cloud and offline products, collect system telemetry, engage with automotive OEMs and suppliers, and define technical roadmaps and design documents for performant offline search on constrained hardware.

Design, build, and maintain scalable backend services and data interfaces. Develop REST/GraphQL APIs, implement data ingestion/transformation, integrate with databases and third-party platforms, ensure security, reliability, and observability, and support CI/CD and infrastructure-as-code workflows.

Design and implement software enabling convergence of 5G NR sidelink and Wi‑Fi 6 ad-hoc links. Build Layer‑3 mesh networking, multi-hop routing, dynamic resource management, EAP‑TLS security, and integration with gNB/UE stacks to optimize latency, reliability, and throughput in distributed wireless environments.

Provide end-to-end testing and test automation for JTS/FAST: create and maintain test cases, execute manual and automated functional, regression, integration, and system tests; report and verify defects; support integration and release activities; maintain test documentation and automation assets; participate in meetings and ensure compliance with NCIA testing standards.

Provide deep technical HPC services: install, publish, benchmark, optimize HPC software on the Rescale platform; support customers and partners; automate workflows; collaborate with sales, product, and engineering to drive customer success and process improvements.

Hands-on senior full-stack engineer to design and build a greenfield, HIPAA-compliant healthcare platform. Ship end-to-end features using Python/Django and React/Next.js, integrate AI/agent workflows, implement secure logging, RBAC, and PHI-safe communications, and collaborate with product and operations to improve patient outcomes and scale care.

Own and patch Chromium/Firefox C++ source to build an in-house stealth browser. Fix fingerprinting at the engine level (navigator, WebGL, canvas, fonts, Client Hints), eliminate CDP leaks, maintain per-OS fingerprint profiles, continuously rebase patches, build validation tooling, and debug detection issues to keep automation indistinguishable from real users.

Define and socialize end-to-end architecture for a multi-tenant, cloud-native SaaS data platform. Lead designs for streaming, low-latency query, multi-cloud deployments, security/compliance, SRE practices, and AI/agent integrations while mentoring senior engineers and influencing executive and customer decisions.

The Senior Software Developer II - Full Stack will design and develop scalable systems, leading projects while mentoring junior staff and engaging with stakeholders. The role emphasizes technical leadership, problem-solving in software development, and innovative processes in cloud and AI technologies.

The Kong API Gateway Specialist will design, implement, and maintain Kong solutions to modernize and secure enterprise APIs, ensuring compliance with federal standards and optimizing API performance.

The Senior Network Engineer manages global network services, focusing on reliability, compliance, and performance while implementing automated solutions and leading incident responses.

Lead modernization of dtn.com as a senior full-stack engineer—improving architecture, performance, accessibility, and integrations. Build responsive front-end experiences and back-end APIs, integrate CMS/CRM/analytics, optimize conversion and SEO, and establish engineering best practices to support marketing, content, and demand-generation goals.

Own and operate Anthropic's endpoint platform: manage MDM as a production service, author configuration-as-code, build zero-touch provisioning and patching automation, run fleet software distribution and telemetry, partner on endpoint security and compliance, and serve as deep escalation for endpoint issues.

As a Senior Mainframe Engineer, you will manage CICS and MQ systems, providing administrative support, troubleshooting, and software deployment while ensuring high availability and optimizing performance.

Assist in developing algorithms for optical transceivers, running tests, collecting data, and establishing manufacturing processes within the PIC test development team.

The DevOps Engineer will design and maintain CI/CD pipelines, manage cloud infrastructure, implement automation tools, and troubleshoot production issues.

The Staff Software Engineer will architect and implement scalable data systems, collaborate with teams, mentor engineers, and ensure data integrity.