Top Remote Python Jobs in San Diego, CA

Reposted 9 Days AgoSaved
Remote
Remote San Diego, CA
150K-220K Annually
Expert/Leader
150K-220K Annually
Expert/Leader
Artificial Intelligence • Big Data • Machine Learning • Security • Software • Cybersecurity • Big Data Analytics
Lead development of the production toolchain that compiles complex Python packages (e.g., NumPy, SciPy, PyTorch). Build and maintain build/release pipelines, create and review conda recipes, automate processes, mentor engineers, run incident response and postmortems, and advise leadership on technical tradeoffs. Partner with distribution and wheels teams and validate AI-assisted code where used.
Top Skills: AutomakeBazelCC++Claude CodeCmakeCondaConda-ForgeCudaCudnnGccGitGlibcHomebrewLibc++Libstdc++LlvmMacos SdkMakeManylinuxPypiPythonRedhat DevtoolsetUcrtVcruntimeWheels
Reposted 9 Days AgoSaved
Remote
Remote San Diego, CA
125K-250K Annually
Mid level
125K-250K Annually
Mid level
Artificial Intelligence • Software • App development
Build and maintain internal developer platforms, tooling, and automation to improve engineering productivity. Implement AI-powered tooling and LLM/agent-driven workflows, create service catalogs and self-service infrastructure, partner with engineering teams to improve reliability, and reduce operational overhead through automation and improved developer experience.
Top Skills: Agentic WorkflowsAi AgentsAirbyteAWSDagsterFluxcdKafkaKubernetesLlmsNestjsPostgresPythonReactRedisTypescript
Reposted 9 Days AgoSaved
Remote
Remote San Diego, CA
160K-200K Annually
Senior level
160K-200K Annually
Senior level
Artificial Intelligence • Healthtech • Software
Lead technical direction and architecture for a software team, write production code, mentor engineers through reviews and pairing, partner with product to align roadmap and technical plans, resolve technical risk and tech debt, and establish engineering standards and tooling.
Top Skills: PythonReactTypescript
Reposted 9 Days AgoSaved
Remote
Remote San Diego, CA
Mid level
Mid level
Renewable Energy
Design, build, and scale embedded connectivity and security for distributed energy devices. Implement networking (Ethernet/Wi‑Fi/Thread/Zigbee/BLE), secure provisioning, OTA firmware pipelines, telemetry, and diagnostics. Support testing, certification, manufacturing validation, and cross-functional collaboration from prototype to deployment.
Top Skills: BleBootloadersCC++CertificatesCi/CdCoapEthernetFreertosHTTPIp NetworkingLogic AnalyzersMqttNetwork SniffersNtpObservability PlatformsProtocol AnalyzersPtpPythonSecure ElementsThreadTlsTpmWebsocketsWi-FiZephyrZigbee
Reposted 9 Days AgoSaved
Remote
Remote San Diego, CA
Senior level
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Software • Database • Analytics
Lead and improve CI/CD and release processes using GitHub Actions; build stress-testing, benchmarking (tsbench) and testing infrastructure; automate packaging and releases; validate TimescaleDB performance in cloud environments and provide regression signals to engineering partners.
Top Skills: Ci/CdGithub ActionsPostgresPythonTsbench
Reposted 9 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
152K-288K Annually
Senior level
152K-288K Annually
Senior level
Artificial Intelligence • Computer Vision • Hardware • Robotics • Metaverse
Develop and maintain GPU performance foundation libraries and test frameworks for Nsight tools. Implement GPU assembly tests, use emulators/simulators to validate instruction events, and document data workflows. Collaborate with hardware architecture teams to enable performance analysis and optimization of GPU-accelerated applications.
Top Skills: CC++CudaEmulatorsGpu AssemblyNsightPythonSimulators
Reposted 9 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
79K-234K Annually
Senior level
79K-234K Annually
Senior level
Legal Tech
Design, build, and maintain web application infrastructure and data systems for interactive information experiences. Lead application architecture, code quality, performance, and reliability; integrate generative AI and prototype XR interfaces; collaborate with designers and data scientists; ensure security, accessibility, scalability, and document technical standards.
Top Skills: AzureCi/CdData ApisData PipelineExtended Reality (Xr)Generative AiJavaScriptLlm ApisPythonReactSpatial ComputingTypescriptVue
Reposted 9 Days AgoSaved
Remote
Remote San Diego, CA
100K-700K Annually
Senior level
100K-700K Annually
Senior level
News + Entertainment
Design, build, and operate scalable, fault-tolerant distributed data infrastructure and platform tooling. Collaborate cross-functionally to architect high-impact systems, contribute to library and platform development, and improve deployment, control, and observability for large-scale data systems.
Top Skills: C++Container TechnologiesGoJavaPythonSpring Boot
Reposted 9 Days AgoSaved
Remote
Remote San Diego, CA
388K-619K Annually
Senior level
388K-619K Annually
Senior level
News + Entertainment
Design, build, and operate scalable, resilient distributed systems for Netflix's Open Connect CDN. Develop cloud services, steering algorithms, deployment automation, data pipelines, and operational tooling to optimize quality-of-experience, hardware utilization, and cost efficiency while enabling real-time adaptation and reliable production operations.
Top Skills: CassandraJavaKafkaNotebooksPythonPyTorchSpark SqlSQLTensorFlow
Reposted 9 Days AgoSaved
Remote
Remote San Diego, CA
388K-619K Annually
Senior level
388K-619K Annually
Senior level
News + Entertainment
Design, build, and operate cloud-native, large-scale distributed data infrastructure (Spark, Presto/Trino, Druid, Iceberg). Improve performance, scalability, and reliability, collaborate cross-functionally, and contribute to open-source projects.
Top Skills: C++DruidGoIcebergJavaNetflix OssPrestoPythonSparkTrino
Reposted 9 Days AgoSaved
Remote
Remote San Diego, CA
388K-619K Annually
Senior level
388K-619K Annually
Senior level
News + Entertainment
Build and maintain internal Python platform libraries and tooling to improve developer experience. Drive runtime, dependency, testing, delivery, monitoring, and performance optimization for Python services (including GPU-enabled workloads). Collaborate cross-functionally to define an opinionated SDLC, support on-call rotations, and balance modern practices with risk-aware change. Enable scalable, low-latency distributed systems and provide AI/ML-facing platform capabilities.
Top Skills: CudaDynamoFastapiFlaskLitserveOnnxPythonPytorch (Torch.Compile)Ray ServeTensorrtTritonVllm
Reposted 9 Days AgoSaved
Remote
Remote San Diego, CA
100K-720K Annually
Senior level
100K-720K Annually
Senior level
News + Entertainment
Design, build, and maintain tools and services for Active Directory and cloud identity platforms. Implement security policies and access controls, collaborate on Azure and Google Workspace deployments, automate integrations via APIs and CI/CD, maintain runbooks, participate in on-call rotation, and support AWS infrastructure for production systems.
Top Skills: Active DirectoryAPIsAWSAzure Ad/Entra IdCi/CdGoGoogle WorkspaceJavaScriptAzureOktaPython
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Reposted 9 Days AgoSaved
Remote
Remote San Diego, CA
120K-145K Annually
Junior
120K-145K Annually
Junior
Financial Services
Design and build backend services, REST APIs, and integrations for bank administrators and customers. Apply domain-driven design and microservice architecture, write well-tested, documented code, and participate in system design, code reviews, and agile SCRUM processes. Integrate with third-party services such as Plaid and SendGrid.
Top Skills: Domain Driven DesignGoMicroservice ArchitectureNestjsNode.jsPlaidPythonReactRest ApisScrumSendgridTypescript
Reposted 9 Days AgoSaved
Remote
Remote San Diego, CA
150K-175K Annually
Senior level
150K-175K Annually
Senior level
Financial Services
Design and build backend services and core user experiences for banks and customers. Implement REST APIs, integrate third-party services (Plaid, SendGrid), apply domain-driven design and microservices, perform system design, code reviews, and mentor teammates.
Top Skills: Agile ScrumDomain-Driven DesignGoMicroservice ArchitectureNestjsNode.jsPlaidPythonReactRest ApisSendgridTypescript
Reposted 9 Days AgoSaved
Remote
Remote San Diego, CA
90K-135K Annually
Mid level
90K-135K Annually
Mid level
Gaming
Lead real-time incident management across online and physical systems, own P1-P4 incident classification, escalation, diagnosis, recovery and RCA. Improve SRE/release processes, drive cross-functional communication, maintain incident documentation, and promote continuous service and release improvements.
Top Skills: AnsibleAWSDockerElastic SearchGCPHelmJIRAKafkaKubernetesLinuxMicrosoft TeamsMySQLPostgresPrometheusPythonRedisSlackTalos LinuxTerraformTerragrunt
Reposted 9 Days AgoSaved
Remote
Remote San Diego, CA
115K-135K Annually
Mid level
115K-135K Annually
Mid level
Software
Design and deliver customer-specific solutions on the Digimarc Illuminate platform: configure accounts, build integrations and web add-ons (Node/JavaScript), script data imports/exports, create demos/POCs, provide 2nd/3rd-level support, and collaborate with product, engineering, and customers to ensure successful deployments.
Top Skills: APIsBashC++Digimarc IlluminateJavaJavaScriptNode.jsPython
10 Days AgoSaved
Remote
Remote San Diego, CA
Mid level
Mid level
Fintech • Information Technology
Designs and scales mission-critical market data services for stocks, options, crypto, and foreign exchange. Responsibilities include developing backend systems, maintaining software quality and test coverage, participating in code reviews, troubleshooting incidents, and building developer-focused APIs and infrastructure using modern cloud, containerization, and orchestration practices.
Top Skills: BigtableDockerElkGoGoogle Kubernetes EngineGrafanaGrpcKubernetesLinuxPrometheusPythonRestSQLSseWebsockets
10 Days AgoSaved
Remote
Remote San Diego, CA
170K-243K Annually
Expert/Leader
170K-243K Annually
Expert/Leader
Aerospace • Defense
Leads mission formulation and architecture for international space opportunities. Develops mission concepts, performs mission-level analyses, owns top-level budgets, defines requirements, evaluates spacecraft and constellation configurations, and guides engineering teams through design trade studies. Collaborates with customers, scientists, and engineering disciplines to create practical, cost-effective satellite missions. Requires regular international travel and occasional travel to the Mountain View facility.
Top Skills: CC++JuliaMatlabPython
Reposted 10 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
Entry level
Entry level
Artificial Intelligence • Marketing Tech • Sales • Software
Build end-to-end user features under senior guidance: implement REST endpoints in Node.js/TypeScript, microservices in Python, maintain PostgreSQL schemas, process background jobs with QStash/Upstash, deploy to Cloudflare Workers/Pages/R2, write tests, and collaborate with product/design on React UI components.
Top Skills: Cloudflare PagesCloudflare R2Cloudflare WorkersCSSHTMLNode.jsPostgresPythonQstashReactSQLTypescriptUpstash
Reposted 10 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
Mid level
Mid level
Artificial Intelligence • Marketing Tech • Sales • Software
Build and maintain end-to-end features across backend (Node.js/TypeScript, Python) and frontend (React/TypeScript). Model Postgres schemas, integrate queues (QStash/Upstash), deploy on Cloudflare edge, write tests, enforce CI/CD, and harden systems for security and performance in regulated environments.
Top Skills: Aws LambdaCloudflare PagesCloudflare WorkersDjangoDurable ObjectsFastapiFlaskGraphQLKafkaNode.jsPostgresPythonQstashR2RabbitMQReactRestTypescriptUpstashVercel
10 Days AgoSaved
Remote
Remote San Diego, CA
Senior level
Senior level
Logistics • Software • Transportation
Lead and grow a backend engineering team while staying hands-on: design and build Python/FastAPI services with Temporal and Postgres, own roadmap and delivery, set SLIs/SLOs, drive observability and reliability, run engineering rituals, hire and coach engineers, and improve quality with DevOps and AI tooling.
Top Skills: AzureCi/CdContainersDockerFastapiKubernetesLoggingMonitoringObservabilityPostgresPostgresPulumiPythonTemporalVue
Reposted 10 Days AgoSaved
Remote
Remote San Diego, CA
Senior level
Senior level
Big Data • Automation
Provide advanced application development, integration, and troubleshooting for DDC/BMS/BAS projects. Configure BACnet/Modbus gateways, develop control databases and interfaces, support commissioning and service teams, review portfolio standards, mentor junior engineers, and participate in customer technical meetings and project lifecycle documentation.
Top Skills: Allen-Bradley PlcsBacnetDelta ControlsDelta DdcEpmsIgnition ScadaJavaScriptKmcModbusMsa Fieldserver ProtonodePythonReliable ControlsSiemens
Reposted 10 Days AgoSaved
Remote
Remote San Diego, CA
Senior level
Senior level
Blockchain • Fintech • Payments • Software
The Senior Full Stack Engineer will design and maintain features across backend and frontend systems, focusing on scalability and security while collaborating on production-grade solutions in a fast-paced environment.
Top Skills: DockerFastapiGCPGoJavaKafkaKubernetesPostgresPythonReactRedis
Reposted 10 Days AgoSaved
Remote
Remote San Diego, CA
140K-175K Annually
Mid level
140K-175K Annually
Mid level
Artificial Intelligence • HR Tech • Information Technology • Machine Learning • Professional Services • Software • Consulting
The Software Engineer will build and own features for the AI-driven matching and screening platform, focusing on data structuring and full-stack development. Collaboration with users and maintaining high quality through testing is essential.
Top Skills: AWSAzureGCPPythonTypescript
Reposted 10 Days AgoSaved
Remote
Remote San Diego, CA
160K-200K Annually
Senior level
160K-200K Annually
Senior level
Artificial Intelligence • HR Tech • Information Technology • Machine Learning • Professional Services • Software • Consulting
The role involves embedding with client teams to build AI features, manage integrations, and ensure project deliveries are met. Candidates must have extensive production software experience and be comfortable working hands-on with clients.
Top Skills: AWSAzureGCPGoKubernetesMlopsPythonTypescript
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