Top Remote Python Jobs in San Diego, CA

Lead high-impact initiatives and architect enterprise-grade APIs while mentoring engineers. Collaborate across teams to influence technical strategy and scale platform architecture.

Own and evolve the company-wide SRE strategy, reliability standards, observability practices, incident management, service ownership, SLOs, and on-call operations. Lead cross-functional reliability initiatives, establish dashboards, alerts, runbooks, and escalation paths, improve production readiness and incident response, and operate large-scale distributed systems across AWS and Kubernetes. Participate in a 24/7 on-call rotation and help shape the SRE function.

Lead the architecture and operation of Horizon3’s developer experience platform, including local development, CI/CD, build systems, container images, artifact promotion, release workflows, security gates, and delivery observability. Build reusable tooling and paved paths, establish secure AI-assisted development practices, improve reproducibility and supply-chain security, and mentor engineers. Partner across Platform, Security, QA, and application teams to drive adoption, reliability, delivery speed, and continuous improvement.

Develop and deploy interactive data and AI applications on Databricks Apps. Build React and TypeScript/JavaScript interfaces, integrate Databricks data, analytics, APIs, and model-serving endpoints, and create lightweight Python or Node.js backend services. Collaborate with data engineers, data scientists, and stakeholders to prototype user workflows, implement governance and security controls, and deliver production-ready applications. Responsibilities also include CI/CD, Git-based development, documentation, Agile collaboration, and translating stakeholder needs into application features.

Designs, automates, and supports enterprise DevOps platforms across on-premises and hybrid cloud environments. Responsibilities include CI/CD, infrastructure as code, Linux administration, Kubernetes and container platforms, Azure and GCP operations, AI/ML infrastructure support, monitoring, reliability engineering, production support, security, disaster recovery, and cloud modernization. The role partners with infrastructure, development, security, architecture, and operations teams while participating in incident management and on-call rotations.

Full-time remote engineering internship with Product Engineering and AI/ML Engineering tracks. Interns may build and optimize scalable product features, contribute to architecture and design decisions, develop data pipelines and machine learning models, deploy AI applications, and integrate LLM-powered capabilities into Chess.com products. Applicants should be enrolled students or equivalent bootcamp participants with strong communication, ownership, teamwork, and relevant programming, database, machine learning, or AI experience.

Own and lead the technical direction of a major codebase section while designing, building, testing, documenting, and maintaining secure, scalable API-based decisioning products. Partner with product, engineering, and security teams on agile delivery, troubleshoot production issues, meet SLA requirements, and participate in an on-call rotation.

Designs and directs development of scalable software systems using AI-assisted engineering practices. Owns architecture, APIs, data models, testing strategy, security, reliability, observability, deployment, and production operations. Decomposes work for AI agents, validates generated code and tests, leads incident response, and coaches engineers on effective AI-enabled development. Requires full-stack experience, modern server-side development, event-driven systems, cloud infrastructure, regulated-data security, and production use of agentic AI.

Lead and mentor a software engineering team, provide technical guidance, drive architecture and engineering excellence, manage sprint execution, collaborate on product roadmaps, ensure scalable and reliable systems, foster continuous improvement, and support recruiting and onboarding. The role requires balancing technical strategy with business impact while developing high-performing engineers.

Design, simulate, prototype, and test RF circuits for wireless infrastructure products. Develop signal-processing algorithms, digital predistortion, and passive intermodulation cancellation techniques. Support TRX design activities, technical documentation, design reviews, subcontractor collaboration, and engineering problem-solving while staying current with RF and microwave technologies.

Lead development and operation of a scalable Kubernetes-based cloud-native platform. Shape the engineering roadmap, deliver enterprise platform capabilities, establish best practices, mentor engineers, and collaborate across Agile teams. Build highly available and fault-tolerant production services using Kubernetes and cloud-native technologies, while applying expertise in Go, Python or Bash, networking, Linux, and CI/CD practices.

Design, simulate, and test RF circuits for cellular base stations, including transmitters, receivers, ADCs, and power supplies. Document designs, participate in reviews, support subcontractors, collaborate with engineering teams, and use RF electromagnetic and analytical simulation tools. The role requires effective planning, communication, technical problem-solving, and occasional international travel.

Develop and support high-volume, mission-critical web applications across the full software development lifecycle. Build with TypeScript, JavaScript, Next.js, and SQL; deploy and operate applications in Microsoft Azure; use AI-assisted development tools; troubleshoot complex technical issues; make architectural decisions; and mentor other engineers. The role requires multi-tier system development, database optimization, Agile collaboration, and proactive delivery of reliable, high-quality software.

Lead the design and operation of AWS and Kubernetes platforms, infrastructure automation, CI/CD, observability, security, and developer self-service capabilities. Drive cross-team platform initiatives, establish technical standards, improve reliability and operational practices, participate in incident response, mentor engineers, and guide architecture for regional and ephemeral environments.

Own and evolve enterprise AWS infrastructure, governance, security, identity, networking, and shared platforms. Build and operate full-stack services in TypeScript and Python, automate infrastructure and delivery, improve monitoring and reliability, manage incidents and on-call operations, and establish audit-ready controls. Partner across engineering and IT, improve production readiness, and mentor engineers while delivering secure, scalable, low-blast-radius systems.

Build, own, deploy, and operate backend services and APIs powering Mozilla products. Responsibilities include backend development, cloud infrastructure collaboration, monitoring and alerting, production support, incident response, releases, security and privacy reviews, API design, code reviews, and mentoring. The role requires end-to-end service ownership, on-call participation, and maintaining reliable production systems.

Build and own backend services for Mozilla’s Ecosystem Services, including server-side logic, APIs, distributed systems, cloud infrastructure, monitoring, deployments, and production reliability. Participate in on-call support, incident response, releases, security and privacy reviews, code reviews, and cross-functional collaboration. Mentor junior engineers and drive improvements in quality, testing, and engineering processes.

Build API-first backend services for workflow orchestration, data ingestion, evaluation, and results management, along with analyst-facing web consoles. Implement identity federation, authentication, authorization, relational data models, automated testing, and CI pipelines. Create API documentation, SDK examples, reference implementations, notebooks, and integration resources. Collaborate with security, infrastructure, platform, and ML engineers while supporting external partners and Government users integrating with published interfaces.

Implements, configures, deploys, and supports software platforms and HL7 interfaces. Troubleshoots operating systems, databases, VPN connectivity, and application integrations; manages customer support tickets, SLAs, documentation, and implementation timelines. Advises customers on technical requirements, collaborates across teams to improve reliability, and participates in an on-call rotation.

Lead and develop an SRE team responsible for the reliability, availability, performance, automation, and observability of Linux-based digital commerce infrastructure. Set SRE and DevOps strategy, modernize Kubernetes and CI/CD practices, establish automation and infrastructure-as-code standards, oversee incident response, and drive SLIs, SLOs, and error budgets. Partner across engineering, architecture, infrastructure, security, networking, and product teams while recruiting, mentoring, and developing SRE talent.

Own products and features end to end, from user research and ideation through MVP launches, iteration, pricing, and ongoing success. Build full-stack experiences, collaborate with design, support customers, resolve production issues, participate in on-call rotations, and write documentation. The role emphasizes autonomous product development, agent-facing software, AI-native products, and rapid shipping.

Own the design, development, and automation of Coinbase’s routing infrastructure connecting services to Kubernetes backends. Build scalable capabilities using Envoy, Istio, Ambient Mesh, and SPIFFE; improve routing latency, reliability, and performance; enhance developer tooling with responsible AI; and collaborate with security, reliability, and observability teams to resolve complex distributed-systems issues.

Design, build, and operate scalable infrastructure and CI/CD/IaC systems. Implement observability (monitoring, logging, alerting), automate reliability improvements, mentor engineers, collaborate on incident response, and participate in on-call rotations to maintain Akamai Cloud services.

Lead a hands-on software engineering effort for Zeta’s real-time events pipeline. Design, build, deploy, and operate high-volume event ingestion, processing, and delivery systems. Own architecture, reliability, observability, performance, cost, data quality, and on-call improvements. Collaborate with Product, Data, and downstream platform teams, define stable interfaces and SLAs, evaluate technologies, lead production launches, and mentor engineers through design and code reviews.

Develops and executes satellite integration, verification, and validation activities across Flatsat, HWIL, SWIL, and simulator environments. Responsibilities include requirements traceability, test planning, automated TCL scripting for TERMA CCS5, formal test conduction, troubleshooting, data analysis, and test reporting. Supports satellite architecture, CONOPS, interface documentation, and requirements development while coordinating multidisciplinary engineering activities.