Top Remote Python Jobs in San Diego, CA

Design, build, and maintain scalable full-stack web applications. Implement backend APIs and responsive frontends, deploy to cloud, ensure security/performance, write tests, debug issues, participate in reviews, and mentor junior developers.

Lead cloud-native platform engineering initiatives: migrate Jenkins pipelines to Harness, move GCVE/on‑prem workloads to GKE, implement GitOps, IaC (Terraform/Ansible), enforce cloud governance and security, build observability and scalable GKE infrastructure, and coach teams on agile and best practices to improve developer productivity.

Build and ship end-to-end product features, debug and resolve production issues, partner with Product on UX and direction, use AI heavily for development and prototyping, and iterate quickly across the stack to improve quality and speed.

Lead technical execution across backend, frontend, mobile, AI, and data. Translate ambiguous product goals into technical plans, unblock hard engineering problems, coordinate cross-domain work, raise engineering quality, define hiring needs and technical evaluation standards, and build internal AI workflows to foster an AI-native engineering culture.

Build and enhance full-stack web applications and APIs using React/TypeScript and Python. Work with PostgreSQL, DynamoDB, AWS, event-driven architectures, CI/CD, and AI-assisted development tools to prototype and improve AI-native engineering workflows.

Lead the design and optimization of scalable data ingestion pipelines, develop reusable ETL components, and mentor junior engineers while leveraging expertise in Python and AWS for the Arine platform.

As a Staff Software Engineer, you'll architect and build foundational platform services, focusing on data infrastructure, healthcare interoperability, and secure APIs while mentoring other engineers.

Seeking a Senior/Staff Backend Engineer to design and maintain scalable backend services for DeFi systems, collaborating closely with a crypto-native team.