Top Remote Python Jobs in San Diego, CA

Develop and maintain internal full-stack applications using C#/Blazor or Python. Build CI/CD pipelines and infrastructure automation with GitLab, Azure DevOps, GitHub, Artifactory, and SonarQube. Partner with cross-functional teams to improve software delivery, code quality, security, compliance, and operational visibility. Implement scalable enterprise solutions, infrastructure as code, secure development practices, and DevSecOps workflows.

Leads the architecture, development, integration, simulation, testing, and fielding of advanced autonomy capabilities for aerospace and defense systems. Responsibilities include radar and RF signal processing, sensing, perception, guidance, navigation, control, sensor fusion, electronic protection, vehicle simulation, requirements development, hardware integration, technical reviews, customer engagement, and mentoring engineering teams.

Lead a team of software engineers building and scaling Spark’s broker productivity platform. Responsibilities include architecting full-stack solutions, guiding technical direction, reviewing code, managing infrastructure priorities, coordinating product planning, sequencing projects, coaching engineers, hiring, and ensuring reliable, high-quality delivery. The role balances hands-on engineering with people management and is fully remote within the United States.

Build and operate scalable, customer-facing full-stack software for Samsara’s safety products. The role involves developing web, mobile, API, and platform capabilities; integrating LLMs, agentic workflows, and RAG; evaluating AI quality; and improving reliability, scalability, and operational health. The engineer collaborates with Product, Design, ML, and platform teams while owning features from concept through production.

Maintain and optimize SaaS production and demo environments, respond to and resolve incidents, manage Jira-based incident workflows, use Dynatrace and observability tools for troubleshooting, automate operational tasks, enforce security best practices, document runbooks in Confluence, participate in on-call rotation, and collaborate cross-team to improve reliability and performance.

Build and maintain enterprise OpenShift/Kubernetes platforms across on-premise, bare-metal, virtualized, and hybrid environments. Develop Operators, APIs, developer tooling, and infrastructure automation using Go, Python, Ansible, and IaC. Implement GitOps CI/CD pipelines, observability, automated recovery, service mesh, secrets management, and self-service capabilities. Collaborate with application teams, improve platform reliability and usability, and mentor engineers while promoting software engineering and SRE best practices.

Build and lead development of high-availability backend services for Affirm’s card loan platform. Design scalable APIs, data models, microservices, and event-driven systems supporting real-time loan attribution, approvals, origination, and refunds. Drive technical strategy, troubleshoot complex performance issues, collaborate with cross-functional teams, and mentor engineers while ensuring long-term system robustness and scalability.

Own Headway’s cloud platform and infrastructure engineering strategy. Lead deployment isolation, container orchestration, AWS networking and compute, autoscaling, capacity planning, Terraform self-service infrastructure, cloud cost attribution, and Python runtime performance. Build reliable paved-road tooling that enables engineering teams to deploy safely and independently while improving scalability, observability, and operational resilience.

Leads architecture and development of SailPoint’s large-scale, multi-tenant identity security SaaS platform. Translates business strategy into technical roadmaps, designs reliable microservices and infrastructure, drives modernization from monoliths to distributed systems, mentors engineers, reviews designs, delivers code, and communicates technology strategy to executives and stakeholders. The role also requires adoption and oversight of AI-assisted engineering tools and technologies.

Owns the full lifecycle of operational software products, from concept through production. Builds and tests reliable, user-focused features; scales prototypes; triages issues and identifies root causes; and partners with product teams, mission engineers, architects, and end users to deliver effective solutions. The role requires strong React, TypeScript, and Python skills, performance optimization experience, and collaboration across technical and non-technical stakeholders.

Leads software teams developing, integrating, deploying, and maintaining full-stack mission applications for DoD and intelligence customers. Builds prototypes and high-performance user interfaces, translates operator needs into features, integrates systems, and conducts deployment and field testing in secure operational environments. The role combines customer collaboration, product discovery, engineering leadership, and software delivery in high-security settings.

Design, operate, and scale SailPoint’s AWS-based Kubernetes infrastructure and service mesh for a global, mission-critical SaaS platform. Responsibilities include cluster architecture, networking, security, GitOps, CI/CD, observability, capacity planning, incident response, compliance, and platform standards. The role influences engineering teams globally, participates in 24x7 on-call support, leads service mesh strategy, and improves reliability, performance, deployment efficiency, and operational practices.

Lead backend engineering strategy for Affirm’s search and recommendation platform. Design and launch highly available distributed systems, guide technical architecture and execution, improve team operations and reliability, establish engineering quality standards, collaborate with product, design, and analytics, and mentor engineers. The role focuses on search, recommendations, consumer shopping experiences, monetization, and scalable platform foundations.

Develop and scale backend streaming and data infrastructure using Kafka, Flink, AWS, Kubernetes, and related technologies. Break down projects, deliver tested software, collaborate with product and engineering teams, monitor system availability, participate in on-call support, debug code, conduct code reviews, and contribute to team development.

Architect, build, and operate large-scale relational and distributed SQL database infrastructure. Responsibilities include database control-plane automation, provisioning, failover, backups, upgrades, zero-downtime migrations, Kubernetes networking, connection proxy optimization, reliability monitoring, capacity planning, and operational support. The role also leads technical delivery, mentors engineers, establishes quality standards, collaborates cross-functionally, and contributes to team roadmap and on-call operations.

Build and operate production-grade Python backend services, APIs, distributed systems, data pipelines, and agentic workflows for an AI observability platform. Own ambiguous projects from prototyping through architecture, testing, deployment, and ongoing operation. Collaborate with product, machine learning, and infrastructure teams, while contributing React front ends when needed. The role requires strong backend depth, distributed-systems expertise, cloud experience, and end-to-end product ownership.

Develops, integrates, documents, and improves automated test systems for aerospace production and verification programs. Responsibilities include creating test methods, data-processing tools, calibration procedures, and software; analyzing and formatting test data; troubleshooting hardware-software integration; and collaborating with engineering, manufacturing, quality, and test teams.

Build, optimize, and maintain software systems using AI while collaborating across disciplines on healthcare technology. Develop distributed, event-driven systems, learn new languages and frameworks, and protect user privacy through data security and HIPAA-compliant practices. The role works with AWS, Kubernetes, and large-scale medical datasets in a fast-paced, mission-driven environment.

Supports Juniper MX and Routing Director platforms in large-scale ISP and data center environments. Plans network deployments, develops implementation plans, tests solutions, troubleshoots hardware and software issues, manages JTAC cases, and delivers documentation, root-cause analyses, briefings, and training. The role requires advanced routing and switching expertise, customer-facing service delivery, network automation knowledge, U.S. citizenship, an active TS/SCI clearance with CI polygraph, and approximately 25% travel.

Develop and maintain CI/CD pipelines, integrations, developer tools, observability systems, and shared developer resources. Troubleshoot production issues through root cause analysis, resolve technical problems, design maintenance procedures, and apply security updates. The role requires collaboration, independent work within established frameworks, and proficiency with Git workflows, Java, Groovy or Python, Docker, Jenkins, and AI prompt engineering.

Provides senior network engineering support for Juniper MX and Routing Director platforms in large-scale ISP and data center environments. Responsibilities include network deployment planning, implementation, testing, troubleshooting, customer support, JTAC case management, root cause analysis, documentation, and technical briefings. The role requires expertise in routing, switching, WAN transport, MPLS, VPNs, automation, and network operations, with remote work and customer-site travel.

Lead technical integrations of Cedar's platform with client healthcare systems: discover requirements, map data formats, validate data/UAT, communicate technical security and authentication needs, manage complex projects, and represent customer needs to engineering and product teams.

Manages the Marketplace Performance software engineering team, setting technical strategy and delivering business-critical backend and consumer marketplace systems. Partners with product, design, analytics, revenue, and merchant teams; oversees system reliability, monitoring, testing, on-call operations, and technical standards. Develops engineering talent, drives quality and ownership, and contributes to Affirm’s ads platform and marketplace monetization initiatives.

Lead and mentor a remote team of 3–6 engineers building and operating CrowdStrike’s internal cloud management platform. Provide technical guidance, code review oversight, architectural input, roadmap execution, hiring support, and professional development. The role involves developing Go and TypeScript APIs and UIs, maintaining highly available cloud infrastructure, collaborating with leadership, and delivering reliable software at scale.

Lead backend engineering strategy for Affirm’s international Identity team. Design and launch highly available distributed systems supporting KYC, user lifecycle management, and identity decisioning. Drive technical planning, cross-functional collaboration, operational excellence, monitoring, testing, and on-call readiness. Establish engineering quality standards, influence architecture, mentor team members, and deliver scalable systems using Python or Kotlin, AWS, MySQL, Spark, and Kubernetes.