Top Machine Learning Jobs in Indianapolis, IN

This is an open talent‑community posting inviting U.S.-based candidates across multiple disciplines (software, AI/ML, XR, UX/UI, DevOps, cybersecurity, data, instructional design, etc.) to submit a resume and brief introduction. HTX Labs will retain candidate information for future contract-to-hire opportunities. Must be authorized to work in the U.S.; no visa sponsorship available. Remote-first role supporting immersive learning for Department of Defense clients.

Lead document-vision research and production systems for multimodal legal evidence understanding. Define evaluation standards, frame hard problems, design and ship models, run efficacy studies and monitoring, mentor senior scientists, and advise leadership on scientific direction.

Senior individual-contributor sales role responsible for hunting net-new consulting engagements across Data, Analytics, and AI. Build pipeline, originate opportunities, manage full sales lifecycle (prospect to signed SOW), engage senior executives, develop value propositions, and partner with technical and delivery teams. Focus on manufacturing and supply chain use cases, modern data platforms, enterprise integration, and ecosystem partners. Travel as needed to develop relationships and close deals.

Drive Midwest SLED revenue by selling analytics-driven SaaS identity and fraud solutions. Build pipeline, manage full sales cycle, develop partnerships/channels, collaborate with product, forecast accurately, and travel up to 50% to close deals and ensure customer success.

Lead product vision and execution for tDesign, an internal platform for small-molecule drug discovery. Define roadmap, translate complex AI/ML and scientific needs into intuitive UX, integrate AI agents and automated workflows, coordinate cross-functional teams, and drive adoption and product impact metrics.

Lead portfolio-level Data & AI strategy and technical governance for enterprise clients. Advise C-suite, drive architecture and modern data stacks, win high-value engagements, and scale engineering and data science teams.

The Engineering Manager will lead teams in developing and managing Blackbaud's Data & AI platform, focusing on scalability, security, and cost-efficiency.

Join Trexquant as a Global Alpha Researcher to develop trading signals, implement research, and apply machine learning for alpha discovery.

Serve as the technical lead in pre-sales for state, local, and education customers: run discovery, design POCs and workshops, deliver demos, map needs to Socure solutions, advise on fraud/risk/compliance, influence product, and mentor junior consultants.

As a Forward Deployed Machine Learning Engineer, you'll build and deploy machine learning models, enhance system performance, and collaborate with Data Science and Engineering teams for effective solutions.

Lead end-to-end deployments of AI for hotel revenue teams: integrate PMS/CRS/RMS, ship ML/optimization models and agentic workflows, validate recommendations with revenue managers, define metrics, drive adoption, and hire/mentor the forward deployed engineering team.

Lead strategy, roadmap, and lifecycle for payer analytics and automation products. Translate market, customer, regulatory, and data insights into product requirements, drive cross-functional delivery with Engineering and Data Science, support go-to-market and adoption, and measure product performance to inform investment and portfolio decisions. Build product practices and partner with stakeholders across sales, customer success, clinical, actuarial, and executive teams.

Lead Growth Engineering architecture and implementation: build Go-based data pipelines, audit/replace martech, create experimentation infrastructure, ship full-stack Go/TypeScript features, productionize ML, review team work, and apply AI-assisted development daily.

Lead and grow a team of 5–6 product developers to deliver high-quality, reliable software. Partner with product and design, champion CI/CD, testing, observability, and provide visibility to leadership while hiring and mentoring engineers.

Own product areas for an autonomous banking platform, translating backend capabilities (APIs, async workflows, ML) into user-facing features. Conduct customer discovery, define technical requirements and acceptance criteria, prioritize backlog, partner with engineering on scoping and de-risking, and validate outcomes using feedback loops and analytics.

Lead complex enterprise sales of AI-powered SaaS solutions, build pipeline, manage 6–12 month high-six-figure deals, multi-thread across stakeholder teams, collaborate with marketing/product/customer success, and translate technical AI capabilities into business ROI.

Lead execution of Product Engineering AI and automation initiatives across photonics products. Build and deploy reusable AI/automation tools, transform engineering data into AI-ready systems, and drive cross-functional adoption to improve development, qualification, manufacturing, and reliability processes.

Own the research-to-production pipeline: harden training/evaluation workflows, build packaging/deployment tooling, design release gates, optimize inference and serving for latency/throughput, establish benchmarking and validation, and instrument feedback from production to accelerate research iteration.

Design, build, and ship production-grade AI and data solutions including LLM-powered applications, ML models, and APIs. Consult on architecture, own features end-to-end, support production, run design-thinking workshops, and collaborate across teams to deliver cloud-based, scalable data and AI capabilities.

Design, build, and ship production-grade AI and data solutions (LLM apps, ML models, APIs). Consult on architecture, own end-to-end features, support deployments, run design workshops, and collaborate cross-functionally to deliver cloud-based data and AI systems.

Design, build, and ship production-grade AI and data solutions (LLM apps, ML models, APIs). Consult on architecture, own features end-to-end, apply cloud and data engineering, lead design thinking workshops, and collaborate across teams to deliver measurable business impact.

Design, train, and productionize underwriting ML models for real-time transaction decisions. Build feature pipelines and training datasets, run experiments, integrate models into batch/real-time systems, and monitor data and model health while collaborating with cross-functional teams.

Lead a consortium advancing AI-driven neurodegeneration research: set strategy, build partnerships, manage multidisciplinary executive team, oversee product development and deployment, secure funding, ensure ethical AI and scientific integrity, and scale the platform to broader biomedical domains.

Lead development of digital twin and simulation models for warehouse operations, deploy AI-driven decision systems, build forecasting and optimization models, validate experiments linking operational metrics to financial impact, and partner with engineers, operations, and external AI/academic partners to scale innovations across fulfillment networks.

The role involves developing and improving TTS/Voice Generation models, training, fine-tuning, evaluating speech models, and collaborating across research, engineering, and product teams in a fast-paced startup environment.