Top Senior Python Jobs in Baltimore, MD

YesterdaySaved
Remote or Hybrid
Baltimore, MD
144K-190K Annually
Senior level
144K-190K Annually
Senior level
Edtech • Information Technology • Software
Lead ownership of Pluralsight's Search backend: build and maintain scalable, reliable ingestion and query systems, design and analyze experiments, consume and produce platform data, collaborate cross-functionally, and participate in on-call rotation to resolve alerts and improve the system.
Top Skills: AlgoliaElasticsearchKafkaNode.jsPostgresPythonTypescript
Reposted 6 Days AgoSaved
In-Office
Baltimore, MD
155K-175K Annually
Senior level
155K-175K Annually
Senior level
Security
The Senior-Level Python Developer will support a cybersecurity initiative, developing network protocol parsers, analytics solutions, and detection capabilities for anomalous network activity.
Top Skills: C++ConfluenceGitGitlabJIRAJupyter NotebooksPythonSpark
Reposted 4 Days AgoSaved
Remote
Baltimore, MD
Senior level
Senior level
Artificial Intelligence • Information Technology • Professional Services • Software
The Senior Full Stack Developer will design, develop, test, and debug software solutions, collaborating with teams and optimizing applications. Responsibilities include user interaction design, back-end functionality, and ensuring software scalability and security.
Top Skills: CSSDjangoDockerFastapiFlaskGitGnu/LinuxHTMLJavaScriptMongoDBMySQLNode.jsOraclePostgresPythonReactSvnVue
Reposted 6 Days AgoSaved
Remote
Baltimore, MD
Senior level
Senior level
Logistics • Software • Transportation
The Principal Python Engineer will design, build, and maintain backend services and APIs, focusing on system reliability and engineering quality. The role involves working with databases, applying DevOps practices, and leveraging AI for development efficiency.
Top Skills: DockerFastapiKubernetesPostgresPulumiPythonTemporalVue
Reposted 6 Days AgoSaved
In-Office or Remote
Baltimore, MD
Senior level
Senior level
Cloud • Software
The Python Engineer will write maintainable Python software, lead technical initiatives, collaborate globally, and contribute to community engagement at Canonical.
Top Skills: CC++DockerGoKubernetesLinuxNoSQLPythonRustSQL
YesterdaySaved
In-Office
Baltimore, MD
Senior level
Senior level
Business Intelligence • Consulting
Designs, develops, tests, and maintains complex software systems for large-scale analytics and real-time processing. Analyzes requirements, debugs defects, documents test results, and recommends improvements and reuse of COTS/GOTS.
Top Skills: Apache AirflowSparkKubernetesPythonTrino
Reposted YesterdaySaved
In-Office
Baltimore, MD
170K-240K Annually
Senior level
170K-240K Annually
Senior level
Big Data • Cloud • Security • Software • Analytics
The Senior Python Software Engineer at GliaCell is responsible for developing and supporting critical software solutions for U.S. Government clients, utilizing Python and various technologies in the cybersecurity domain.
Top Skills: AnsibleAWSDockerElasticsearchGitlab Ci/CdGrafanaKubernetesPythonSplunk
Reposted 20 Days AgoSaved
Easy Apply
Remote or Hybrid
Baltimore, MD
Easy Apply
126K-248K Annually
Senior level
126K-248K Annually
Senior level
Big Data • Cloud • Software • Database
The Senior Python Engineer will develop and support MongoDB Python drivers, enhance library quality, and collaborate on product features.
Top Skills: Ai/Ml FrameworksMongoDBPypiPython
Reposted 6 Days AgoSaved
In-Office
Baltimore, MD
155K-175K Annually
Senior level
155K-175K Annually
Senior level
Security
The Senior-Level Full-Stack Developer will capture software requirements, develop and deploy analytic solutions, and ensure compliance with policies.
Top Skills: JavaJupyterPython
Reposted 6 Days AgoSaved
In-Office
Baltimore, MD
155K-175K Annually
Senior level
155K-175K Annually
Senior level
Security
The Principal-Level Software Engineer develops custom analytics, integrates solutions, collaborates with data scientists, and supports operationalizing data science at scale.
Top Skills: ConfluenceGitlabJavaJava MapreduceJIRAJupyter NotebooksPythonPython Pyspark
Reposted 6 Days AgoSaved
In-Office
Baltimore, MD
155K-175K Annually
Senior level
155K-175K Annually
Senior level
Security
The Senior-Level Analytic Engineer will develop and deploy analytic capabilities, maintain applications, and collaborate with stakeholders to enhance network data analysis.
Top Skills: JavaJupyter NotebooksMapreducePython
Reposted 6 Days AgoSaved
In-Office
Baltimore, MD
170K-260K Annually
Senior level
170K-260K Annually
Senior level
Big Data • Cloud • Security • Software • Analytics
Develop, test, deploy, and sustain Python-based REST endpoints and microservices using Django/Flask, interfacing with MariaDB or MongoDB, providing middleware and backend support for mission-critical government systems focused on automation and continuous monitoring.
Top Skills: DjangoDockerFlaskJSONMariadbMicroservicesMongoDBPythonRest
New

Track Smarter, Apply Better.

Ditch the spreadsheets. Organize your job search with our freeApplication Tracker.

Use For Free
Application Tracker Preview
130K-270K Annually
Senior level
Software
Administer, maintain, and support a secure, multi-tenant PaaS Kubernetes platform on Linux. Ensure reliability, scalability, security compliance, performance tuning, troubleshooting of containerized workloads, implement IaC/automation, deploy Helm charts, and monitor with Prometheus/Grafana.
Top Skills: AnsibleBashDockerGitGrafanaHelmKubernetesLinuxPodmanPrometheusPython
130K-270K Annually
Senior level
Software
Develop, sustain, and troubleshoot the project's software suite. Implement, test, and integrate with COTS/FOSS components. Build containerized services, create Helm charts, support CI/CD pipelines, and script/administer on Linux using Bash/Python and Java/Spring. Collaborate to deliver mission-focused capabilities.
Top Skills: AnsibleBambooBashDockerGitGitlab CiHelmJavaKafkaKubernetesLinuxMongoDBNoSQLPythonRabbitMQSpring BootSpring DataSpring Integration
Reposted 16 Hours AgoSaved
Remote
Baltimore, MD
139K-203K Annually
Senior level
139K-203K Annually
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Marketing Tech • Software • Biotech • Design
Develop and maintain backend solutions, ensuring performance, security, and regulatory compliance, while collaborating in cross-functional teams.
Top Skills: AWSFastapiPython
Reposted YesterdaySaved
Remote
Baltimore, MD
Senior level
Senior level
Information Technology • Consulting
Design and build applications using Python, manage component design, optimize performance, and collaborate with clients on innovative products.
Top Skills: Ai ToolsCi/CdGitGoKubernetesPythonReact
25 Days AgoSaved
Remote
Baltimore, MD
1M-2M Annually
Senior level
1M-2M Annually
Senior level
Agency • Information Technology • Software • App development
Design, develop, and maintain scalable Python applications and cloud-native solutions. Architect microservices, containerized deployments (Docker/Kubernetes), optimize cloud infrastructure, build CI/CD pipelines, integrate messaging systems, ensure security and high code quality, and mentor junior developers. Generative AI/ML experience is a plus.
Top Skills: AWSAzureAzure PipelinesCi/CdCosmosdbDjangoDockerFastapiFlaskGenerative AiGitlab CiGCPHugging FaceJenkinsKafkaKubernetesPythonPyTorchRabbitMQRdsRest ApisServerlessTensorFlowWebsockets
Reposted 3 Days AgoSaved
Remote
Baltimore, MD
130K-165K Annually
Senior level
130K-165K Annually
Senior level
HR Tech • Legal Tech • Software • Consulting
Design, implement, and maintain SaaS features using Python and React on AWS. Lead system design, code reviews, CI/CD pipelines, AI-integrated development (LLMs and AI coding agents), prompt engineering, testing (Cypress), and on-call production support. Mentor teammates and ensure secure, scalable, well-documented software.
Top Skills: AWSCicdClaude CodeCodexContainerized EnvironmentsCypressDevin.AiLlmMcpMySQLPython 3.11ReactRestful Apis
Reposted 13 Days AgoSaved
In-Office
Baltimore, MD
113K-238K Annually
Senior level
113K-238K Annually
Senior level
Information Technology • Consulting • Defense
Develop middleware and backend support for applications, create Python ReST endpoints, manage data models, and improve software documentation and processes.
Top Skills: AWSDjangoFlaskJSONMariadbMicroservicesMongoDBPythonRestXML
Reposted 4 Days AgoSaved
In-Office or Remote
Baltimore, MD
135K-155K Annually
Senior level
135K-155K Annually
Senior level
Machine Learning • Other
The Backend Software Engineer will develop and maintain backend systems for data processing related to coffee farming, utilizing Python and PostgreSQL. Responsibilities include feature development, problem-solving, and adapting systems to regulatory changes while ensuring system resilience.
Top Skills: AWSCi/CdDockerPostgresPostgresql/PostgisPythonTerraform
Reposted 5 Days AgoSaved
Remote
Baltimore, MD
Senior level
Senior level
Healthtech • Software
Lead and code fullstack features for the EVV team, provide technical leadership and mentoring, design and execute automated tests, monitor and troubleshoot production, contribute to product technical roadmap, and leverage AI-assisted development tools.
Top Skills: AWSCi/CdClaudeCursorDockerGitJavaScriptPHPPytestPythonSQLSqlalchemyVue
Reposted 5 Days AgoSaved
Remote
Baltimore, MD
Senior level
Senior level
Software
Lead the design and development of scalable Python backend services and APIs on AWS, mentor engineers, and manage PostgreSQL databases in a healthcare technology environment.
Top Skills: Api GatewayAWSBitbucketDockerGitJIRAKubernetesLambdaOauth 2PostgresPythonRest ApiSlackTeams
130K-270K Annually
Senior level
Software
Administer, maintain, and support a secure, multi-tenant Kubernetes PaaS on Linux. Ensure reliability, scalability, security compliance, and performance. Troubleshoot Kubernetes workloads, develop automation and scripts (Bash/Python), manage IaC (Ansible), Helm charts, containerization, and monitoring (Prometheus/Grafana). Collaborate via Git and support mission application requirements.
Top Skills: AnsibleBashDockerGitGrafanaHelmKubernetesLinuxPodmanPrometheusPython
15 Days AgoSaved
In-Office
Baltimore, MD
130K-270K Annually
Senior level
130K-270K Annually
Senior level
Software
Senior test engineer responsible for testing and validating HPC systems against test plans. Develop and execute test plans, automate tasks with Bash/Python, test REST APIs, create complex SQL/Splunk queries, analyze logs and results with Splunk/Kibana/Grafana, track and resolve defects, and support CI/CD pipelines using GitLab CI.
Top Skills: BashCi/CdGitGitlabGitlab CiGrafanaHpcKibanaLinuxPythonRest ApisSplunkSQL
15 Days AgoSaved
In-Office
Baltimore, MD
130K-270K Annually
Senior level
130K-270K Annually
Senior level
Software
Develop, sustain, and troubleshoot a suite of mission-focused software applications. Implement, test, and integrate with COTS/GOTS/FOSS; build containerized services (Docker, Kubernetes, Helm); work with NoSQL/Databases, messaging, CI/CD, and IaC. Support evolving mission needs while holding required security clearance.
Top Skills: AnsibleBashDockerGitGitlab CiHelmKubernetesLinuxMongoDBNoSQLPythonRabbitMQRust
All Filters
JobType
New Jobs
Job Category
Experience
Industry
Company Name
Company Size

Sign up now Access later

Create Free Account