Top Senior Python Jobs in Baltimore, MD

Reposted 9 Days AgoSaved
In-Office
Baltimore, MD
155K-175K Annually
Senior level
155K-175K Annually
Senior level
Security
The Senior-Level Python Developer will support a cybersecurity initiative, developing network protocol parsers, analytics solutions, and detection capabilities for anomalous network activity.
Top Skills: C++ConfluenceGitGitlabJIRAJupyter NotebooksPythonSpark
YesterdaySaved
Remote
Baltimore, MD
1M-2M Annually
Senior level
1M-2M Annually
Senior level
Agency • Information Technology • Software • App development
Design, develop, and maintain scalable Python applications and cloud-native solutions. Architect microservices, containerized deployments (Docker/Kubernetes), optimize cloud infrastructure, build CI/CD pipelines, integrate messaging systems, ensure security and high code quality, and mentor junior developers. Generative AI/ML experience is a plus.
Top Skills: AWSAzureAzure PipelinesCi/CdCosmosdbDjangoDockerFastapiFlaskGenerative AiGitlab CiGCPHugging FaceJenkinsKafkaKubernetesPythonPyTorchRabbitMQRdsRest ApisServerlessTensorFlowWebsockets
Reposted 5 Days AgoSaved
Remote
Baltimore, MD
Senior level
Senior level
Artificial Intelligence • Information Technology • Professional Services • Software
The Senior Full Stack Developer will design, develop, test, and debug software solutions, collaborating with teams and optimizing applications. Responsibilities include user interaction design, back-end functionality, and ensuring software scalability and security.
Top Skills: CSSDjangoDockerFastapiFlaskGitGnu/LinuxHTMLJavaScriptMongoDBMySQLNode.jsOraclePostgresPythonReactSvnVue
Reposted 7 Days AgoSaved
Remote
Baltimore, MD
Senior level
Senior level
Logistics • Software • Transportation
The Principal Python Engineer will design, build, and maintain backend services and APIs, focusing on system reliability and engineering quality. The role involves working with databases, applying DevOps practices, and leveraging AI for development efficiency.
Top Skills: DockerFastapiKubernetesPostgresPulumiPythonTemporalVue
Reposted 7 Days AgoSaved
In-Office or Remote
Baltimore, MD
Senior level
Senior level
Cloud • Software
The Python Engineer will write maintainable Python software, lead technical initiatives, collaborate globally, and contribute to community engagement at Canonical.
Top Skills: CC++DockerGoKubernetesLinuxNoSQLPythonRustSQL
Reposted 2 Days AgoSaved
In-Office
Baltimore, MD
170K-260K Annually
Senior level
170K-260K Annually
Senior level
Big Data • Cloud • Security • Software • Analytics
The Senior Python Software Engineer at GliaCell is responsible for developing and supporting critical software solutions for U.S. Government clients, utilizing Python and various technologies in the cybersecurity domain.
Top Skills: AnsibleAWSDockerElasticsearchGitlab Ci/CdGrafanaKubernetesPythonSplunk
Reposted 22 Days AgoSaved
Easy Apply
Remote or Hybrid
Baltimore, MD
Easy Apply
126K-248K Annually
Senior level
126K-248K Annually
Senior level
Big Data • Cloud • Software • Database
The Senior Python Engineer will develop and support MongoDB Python drivers, enhance library quality, and collaborate on product features.
Top Skills: Ai/Ml FrameworksMongoDBPypiPython
Reposted 5 Days AgoSaved
In-Office
Baltimore, MD
130K-270K Annually
Senior level
130K-270K Annually
Senior level
Software
The DevOps Engineer will implement infrastructure, automate deployment processes, manage Kubernetes containers, and ensure service reliability, scalability, and continuous improvement.
Top Skills: AnsibleAWSGitKubernetesLinuxPythonTerraform
Reposted 5 Days AgoSaved
In-Office
Baltimore, MD
130K-270K Annually
Senior level
130K-270K Annually
Senior level
Software
The Cloud Platform Engineer will develop software components, integrate open-source code, and manage virtual infrastructure in AWS, requiring strong systems integration skills and cloud technology experience.
Top Skills: AWSJavaLinuxPython
Reposted 5 Days AgoSaved
In-Office
Baltimore, MD
130K-270K Annually
Senior level
130K-270K Annually
Senior level
Software
Looking for a Cloud Platform Engineer to develop custom software, manage infrastructure in AWS, and solve complex problems autonomously in a hybrid environment.
Top Skills: AnsibleAWSCi/CdConfluenceGitGitlabJavaJIRAKubernetesLinuxMavenPuppetPythonShell
Reposted 5 Days AgoSaved
In-Office
Baltimore, MD
130K-270K Annually
Senior level
130K-270K Annually
Senior level
Software
Seeking a highly motivated DevOps Engineer with extensive experience in AWS, Linux, and automation. Responsibilities include managing cloud infrastructure, automating deployment processes, and collaborating with development teams to enhance reliability and performance.
Top Skills: AnsibleAWSBashGitKubernetesLinuxPythonTerraform
Reposted 5 Days AgoSaved
In-Office
Baltimore, MD
130K-270K Annually
Senior level
130K-270K Annually
Senior level
Software
The DevOps Engineer will automate deployment processes, manage cloud infrastructure, and collaborate with development teams to ensure reliable services. This role involves troubleshooting, monitoring systems, and continuous improvement of processes.
Top Skills: AnsibleAWSBashCi/CdDrillEksElasticsearchGitHadoopHiveImpalaJavaKubernetesLinuxPostgresPrestoPythonSparkTerraformTrino
New

Track Smarter, Apply Better.

Ditch the spreadsheets. Organize your job search with our freeApplication Tracker.

Use For Free
Application Tracker Preview
Reposted 5 Days AgoSaved
In-Office
Baltimore, MD
130K-270K Annually
Senior level
130K-270K Annually
Senior level
Software
The Cloud Platform Engineer will develop software components, manage cloud infrastructure in AWS, and ensure system integration while enhancing existing codebases.
Top Skills: AWSBashCi/CdConfluenceDockerGitGitlabJavaJIRALinuxPythonShell
Reposted 9 Days AgoSaved
In-Office
Baltimore, MD
155K-175K Annually
Senior level
155K-175K Annually
Senior level
Security
The Senior-Level Full-Stack Developer will capture software requirements, develop and deploy analytic solutions, and ensure compliance with policies.
Top Skills: JavaJupyterPython
Reposted 9 Days AgoSaved
In-Office
Baltimore, MD
155K-175K Annually
Senior level
155K-175K Annually
Senior level
Security
The Principal-Level Software Engineer develops custom analytics, integrates solutions, collaborates with data scientists, and supports operationalizing data science at scale.
Top Skills: ConfluenceGitlabJavaJava MapreduceJIRAJupyter NotebooksPythonPython Pyspark
Reposted 9 Days AgoSaved
In-Office
Baltimore, MD
155K-175K Annually
Senior level
155K-175K Annually
Senior level
Security
The Senior-Level Analytic Engineer will develop and deploy analytic capabilities, maintain applications, and collaborate with stakeholders to enhance network data analysis.
Top Skills: JavaJupyter NotebooksMapreducePython
Reposted 11 Hours AgoSaved
Remote
Baltimore, MD
Senior level
Senior level
Travel
As a Staff Software Engineer, you’ll lead the design and reliability of Duetto's data lakehouse, evolving data systems using Python and AWS, ensuring data quality, and implementing AI-driven solutions.
Top Skills: AirflowAWSDatadogDockerGithub ActionsGlueIcebergPysparkPythonSagemakerSentrySumo LogicTerraform
Reposted YesterdaySaved
Remote
Baltimore, MD
139K-203K Annually
Senior level
139K-203K Annually
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Marketing Tech • Software • Biotech • Design
Develop and maintain backend solutions, ensuring performance, security, and regulatory compliance, while collaborating in cross-functional teams.
Top Skills: AWSFastapiPython
Reposted 11 Days AgoSaved
In-Office
Baltimore, MD
Senior level
Senior level
Business Intelligence • Consulting
The Sr. Software Engineer develops and enhances software systems, implements data pipelines, monitors data science tools, and integrates model outputs within security systems while adhering to software design methodologies.
Top Skills: AWSDockerKubernetesNumpyPandasPythonPyTorchScikit-Learn
Reposted 2 Days AgoSaved
Remote
Baltimore, MD
Senior level
Senior level
Information Technology • Consulting
Design and build applications using Python, manage component design, optimize performance, and collaborate with clients on innovative products.
Top Skills: Ai ToolsCi/CdGitGoKubernetesPythonReact
4 Days AgoSaved
Remote
Baltimore, MD
165K-215K Annually
Senior level
165K-215K Annually
Senior level
Legal Tech • Software
Design and implement durable, fault-tolerant AI orchestration and backend systems using Temporal and agentic ReAct patterns. Deliver features end-to-end with testing, CI/CD, monitoring, and observability; mentor engineers and collaborate with cross-functional teams to translate legal workflows into reliable AI-powered features.
Top Skills: Async/AwaitClaude (Llm)Event-Driven ArchitectureFastapiGitlab Ci/CdMessage QueuesNew Relic ApmOctopus DeployPlaywrightPydantic V2Pydantic-AiPytestPython 3.12+ReactStructlogSyrupyTemporal
5 Days AgoSaved
Remote
Baltimore, MD
130K-165K Annually
Senior level
130K-165K Annually
Senior level
HR Tech • Legal Tech • Software • Consulting
Design, implement, and maintain SaaS features using Python and React on AWS. Lead system design, code reviews, CI/CD pipelines, AI-integrated development (LLMs and AI coding agents), prompt engineering, testing (Cypress), and on-call production support. Mentor teammates and ensure secure, scalable, well-documented software.
Top Skills: AWSCicdClaude CodeCodexContainerized EnvironmentsCypressDevin.AiLlmMcpMySQLPython 3.11ReactRestful Apis
Reposted 14 Days AgoSaved
In-Office
Baltimore, MD
170K-260K Annually
Senior level
170K-260K Annually
Senior level
Big Data • Cloud • Security • Software • Analytics
Develop, test, deploy, and sustain Python-based REST endpoints and microservices using Django/Flask, interfacing with MariaDB or MongoDB, providing middleware and backend support for mission-critical government systems focused on automation and continuous monitoring.
Top Skills: DjangoDockerFlaskJSONMariadbMicroservicesMongoDBPythonRest
Reposted 14 Days AgoSaved
In-Office
Baltimore, MD
113K-238K Annually
Senior level
113K-238K Annually
Senior level
Information Technology • Consulting • Defense
Develop middleware and backend support for applications, create Python ReST endpoints, manage data models, and improve software documentation and processes.
Top Skills: AWSDjangoFlaskJSONMariadbMicroservicesMongoDBPythonRestXML
5 Days AgoSaved
In-Office or Remote
Baltimore, MD
160K-190K Annually
Senior level
160K-190K Annually
Senior level
eCommerce • Fintech • Payments • Software
Design and build end-to-end AI-driven automation to replace manual operational workflows. Partner with ops, sales, and support to discover problems, architect agentic orchestration, deploy production systems, measure impact, and iterate with robust guardrails and error handling.
Top Skills: Ai AgentsApexAutogenAWSAzureCi/CdClaude CodeCrewaiCursorGCPGitGithub ActionsGithub CopilotJavaScriptJIRALanggraphLightningLlmsPythonSalesforceSalesforce ApisSlackTypescriptWindsurf
All Filters
JobType
New Jobs
Job Category
Experience
Industry
Company Name
Company Size

Sign up now Access later

Create Free Account