Top Senior Python Jobs in Baltimore, MD

Plans, develops, executes, and automates testing for software, middleware, and infrastructure in HPC environments. Validates reliability, scalability, performance, security, and operational readiness; develops test plans, automated frameworks, and validation solutions; tests REST APIs; manages defects and test lifecycles; and supports CI/CD integration using GitLab, containers, Linux, Bash, Python, and Git.

Administer, maintain, monitor, and support a secure, highly available Kubernetes PaaS running on Linux infrastructure. Troubleshoot workloads, networking, storage, ingress, and performance issues; develop Bash and Python scripts; manage Docker or Podman containers; create Helm charts; apply infrastructure-as-code with Ansible; and use Prometheus, Grafana, and Git to maintain platform reliability, scalability, and compliance.

Develops and secures access-control and permission-management solutions for critical HPC systems. Responsibilities include Linux security administration, RBAC/ABAC, IAM with Keycloak, identity federation, SSO, Vault integrations, Ansible automation, containerization, CI/CD, and Git-based development. The role requires maintaining compliance with agency security policies and industry standards while supporting mission-critical government systems.

Develop and maintain software supporting U.S. government missions. The role involves daily software engineering responsibilities using Python, PySpark, and AWS services including Lambda, Glue, and DynamoDB. Candidates must hold an active Top Secret/SCI clearance with a favorable polygraph and be U.S. citizens. The position requires seven years of relevant software engineering experience and a bachelor's degree or an approved experience substitution.

Systems Engineer supporting a closed, multi-location system across capabilities and operations. Responsibilities include Linux system administration, Bash/Python automation, STE/STN security compliance, Cisco switch configuration, containerization with Docker or Podman, and technical documentation. Preferred experience includes Windows administration, NetApp storage, VMware virtualization, and Atlassian tools. The role requires collaboration with customer stakeholders and a current Top Secret/SCI clearance with favorable polygraph.

Maintains, troubleshoots, upgrades, and integrates containerized applications deployed in Kubernetes and Linux environments. Develops software and automation using Python, Java, Bash, PHP, and Ansible; manages CI/CD workflows with GitLab and source control with Git. Supports mission services, documents configurations and system changes, assists external customers, and may provide training. Requires extensive COTS/GOTS integration experience and an active Top Secret/SCI clearance with favorable polygraph.

Integrates, tests, evaluates, configures, upgrades, and troubleshoots high-performance computing software stacks and systems. Develops Bash and Python automation, administers Linux environments, supports Slurm scheduling, and uses IaC tools including Ansible and Salt. Diagnoses software, hardware, networking, storage, and system-monitoring issues across heterogeneous HPC environments. Requires extensive experience supporting large-scale HPC systems and customers.

Designs, develops, deploys, and supports production software in high-performance Linux environments. Builds containerized applications and Kubernetes services using Python, Helm, and CI/CD automation. Develops generative AI solutions involving LLMs, RAG, embeddings, vector databases, and inference systems. Supports observability with Prometheus and Grafana, applies DevSecOps practices, and delivers secure, scalable mission-critical systems in a cleared environment.

Designs, implements, and optimizes data ingress and egress pathways for scalable analytics workloads. Develops software using Python and Java, automates processes with Bash, orchestrates workflows through Apache Airflow, and processes large datasets with Apache Spark. Responsibilities include SQL-based data manipulation, data wrangling, validation, anomaly detection, and handling structured and unstructured data. Requires a current Top Secret/SCI clearance with favorable polygraph.

Develop and maintain software supporting U.S. government mission needs using Python, Kotlin, Java, Terraform, Elasticsearch/OpenSearch, and AWS. The engineer will assist with daily software engineering responsibilities, innovate solutions, and contribute to projects of similar scope and complexity. The role requires a current Top Secret/SCI clearance with favorable polygraph, U.S. citizenship, seven years of software engineering experience, and a relevant bachelor’s degree or qualifying experience substitution.

Develop and maintain Java-focused backend libraries and services that ingest, transform, and standardize diverse data formats. Build Python components, optimize MongoDB services, administer Linux systems, upgrade servers, install packages, monitor services, and troubleshoot environments. Contribute to scalable architecture, data modeling, integration patterns, Git workflows, code reviews, and continuous improvement. The role is onsite, requires U.S. citizenship, and involves a Top Secret SCI with Polygraph clearance.

Own the technical foundation of a manufacturing software product, including auditing and hardening the existing codebase, designing architecture, shipping full-stack features, integrating ERP systems, evolving data models, building real-time capabilities, and managing infrastructure, deployment, and monitoring. The founding engineer will engage users, guide product decisions, establish engineering standards, help hire future engineers, and contribute to AI-powered features.

Design and build applications using Python, manage component design, optimize performance, and collaborate with clients on innovative products.

Own Telnyx’s global phone-number ordering pipeline, carrier integrations, regulatory automation, AI-powered order review, and Postgres data layer. Build reliable async Python services with retries, rollbacks, queues, SLA monitoring, document verification, auditability, and human escalation. Improve automation across dozens of vendors and 45+ countries while maintaining dashboards, analytics, and operational alerts across a large microservice estate.

Design, develop, and maintain scalable Python applications; collaborate with cross-functional teams to deliver features; ensure performance and quality; identify and fix bugs; maintain code quality and automation; lead and mentor team members using agile practices.

Lead the design, development, and implementation of resilient pricing tools using Python and cloud technologies. Improve automation, deployment reliability, testing, documentation, and technical standards. Coordinate complex projects, research new development practices, identify technical blockers, and mentor junior developers. Collaborate with stakeholders while developing expertise in insurance pricing and supporting applications built with technologies such as Streamlit, Flask, Docker, Kubernetes, and cloud compute.

Designs and builds scalable applications using React and Python, contributing to component development, data storage, deployment practices, performance optimization, testing, and client requirements analysis. The role collaborates with technical leaders, clients, and distributed teams in agile environments, using Git, code reviews, cloud platforms, databases, and AI-native development practices. U.S.-based travel to client sites is required.

Design, develop, and maintain scalable Python applications and cloud-native solutions. Architect microservices, containerized deployments (Docker/Kubernetes), optimize cloud infrastructure, build CI/CD pipelines, integrate messaging systems, ensure security and high code quality, and mentor junior developers. Generative AI/ML experience is a plus.

Evaluate AI coding agents such as Codex, Claude Code, and Cursor for engineering judgment, response quality, reasoning, explanations, and usefulness. Provide clear written and recorded feedback, distinguish quality levels, and help define standards for excellent AI-assisted development interactions. This contract role requires senior-level software engineering experience, strong Python or TypeScript/JavaScript skills, familiarity with modern AI development workflows, and excellent English communication.

Build, maintain, and scale e-commerce backend services using Python and Django. Develop REST APIs and features for catalogs, inventory, carts, checkout, orders, payments, and accounts. Integrate third-party services, optimize databases and performance, implement security controls, write tested code, resolve production issues, and collaborate on architecture, planning, reviews, deployment, and CI/CD.

Build and maintain full-stack applications that deliver AI/ML insights through backend services, REST APIs, containerized microservices, and high-performance front-end interfaces. Responsibilities include cloud-native development on Google Cloud or Azure, database management, testing, CI/CD automation, security, troubleshooting, and Agile collaboration.

Develop and sustain mission-critical government software and systems as a senior Python engineer. Apply Python and related technologies including Kotlin/Java, Terraform, Elasticsearch, OpenSearch, and AWS. Work independently and collaboratively on software engineering projects, support customer mission needs, and contribute to reliable solutions using Agile development practices. The position requires a TS/SCI with Polygraph clearance and supports partial telework after acclimation and training.

Develop and sustain mission-critical software and systems for a U.S. Government customer. Apply Python and related technologies including Kotlin/Java, Terraform, Elasticsearch/OpenSearch, and AWS. Collaborate independently and within engineering teams while supporting reliable software solutions, Agile development, and mission-focused technical initiatives. The role requires a TS/SCI with Polygraph clearance and is based in Annapolis Junction with partial telework available after acclimation and training.

Develop and sustain mission-critical software for a U.S. Government customer using Python, PySpark, and AWS services including Lambda, Glue, and DynamoDB. The role requires software engineering experience, collaboration, strong communication, and an active or reinstatable TS/SCI clearance with polygraph. The position is based in Annapolis Junction, Maryland, with partial telework potentially available after acclimation and training.

Develop and sustain a high-performance geospatial collaboration and intelligence reporting tool. Responsibilities include implementing mission-driven enhancements, maintaining existing code, troubleshooting application interfaces, testing, integration, and resolving production issues. The developer will work with Java, C/C++, scripting languages, databases, search platforms, REST services, and Linux. Participation in a rotating pager schedule is required for emergency 24/7 support.