Top Senior Software Engineer Jobs in St. Louis, MO

6 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
186K-219K Annually
Senior level
186K-219K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Design, build, and operate Kubernetes-based compute orchestration and developer tooling. Deliver new compute capabilities, automate operations and observability, integrate AI into workflows, and partner with Security and Reliability to ensure platform scalability, performance, and incident response.
Top Skills: Ai ToolingArgocdAWSEc2EcsEfsEksEnvoyGCPGenerative AiHelmIamIstioKubernetesMesosNomadPrometheusVpc
Reposted YesterdaySaved
Remote
St. Louis, MO
140K-160K Annually
Senior level
140K-160K Annually
Senior level
Information Technology • Real Estate • Software • PropTech
As a Full Stack Software Engineer, you will develop and maintain robust backend systems using Ruby on Rails, collaborating with cross-functional teams to enhance the real estate platform's performance and user experience.
Top Skills: AWSCSSDjangoGatsbyHerokuHotwireNextjsRuby On RailsSeleniumStimulusTailwindcssTurboVercel
Reposted 6 Days AgoSaved
Remote or Hybrid
St. Louis, MO
160K-195K Annually
Senior level
160K-195K Annually
Senior level
AdTech • Consumer Web • Digital Media • eCommerce • Marketing Tech
The Senior Software Engineer will design and optimize recommendation algorithms, maintain data pipelines, and improve personalized user experiences using machine learning techniques and backend engineering skills.
Top Skills: AirflowApache KafkaAws SagemakerBeamDockerElasticsearchFlinkGcp Vertex AiGrafanaJaxKibanaKubernetesNode.jsPythonPyTorchSparkTensorFlowTypescript
Reposted 6 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
169K-240K Annually
Senior level
169K-240K Annually
Senior level
Big Data • Fintech • Mobile • Payments • Financial Services
The role involves designing and expanding backend systems, mentoring engineers, and executing technical strategies to modernize architecture and improve system performance.
Top Skills: AWSGrpcJavaKotlinKubernetesMySQLPythonSnowflake
Reposted 6 Days AgoSaved
Remote
St. Louis, MO
173K-203K Annually
Senior level
173K-203K Annually
Senior level
Healthtech • Social Impact • Software • Telehealth
As a Senior Software Engineer, you will build and integrate marketing technology stacks, lead technical projects, collaborate with cross-functional teams, and foster a high-performing engineering culture.
Top Skills: AWSClaude CodeCursorDockerGCPGithub CopilotKafkaKubernetesNode.jsPostgresReactTypescript
Reposted 7 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
186K-219K Annually
Senior level
186K-219K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
The Senior Software Engineer will build user features using Golang and cloud technologies, lead tool implementation, and collaborate across teams to enhance productivity.
Top Skills: Ai/Ml TechnologiesAWSBuildkiteGoGraphQLGrpcKafkaKubernetesNoSQLSQLTerraform
7 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
Senior level
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Build and scale full-stack customer and agent support experiences across React/TypeScript frontends and Go backend services. Own APIs, integrations, and AI/ML vendor integrations, drive CX outcomes through experimentation and metrics, improve reliability through on-call incident response, and collaborate with Product, Design, and Ops to deliver measurable product outcomes.
Top Skills: Ai/MlGenerative AiGoReactTypescript
7 Days AgoSaved
Easy Apply
Remote or Hybrid
St. Louis, MO
Easy Apply
131K-220K Annually
Senior level
131K-220K Annually
Senior level
Artificial Intelligence • Cloud • Computer Vision • Hardware • Internet of Things • Software
Design, build, and operate scalable, secure data platform infrastructure for ingesting, processing, cataloging, and accessing petabytes of data. Improve Spark/Databricks reliability and developer experience, build ingestion/replication systems, develop internal libraries and tooling (Go/Python), and collaborate with cross-functional teams to support analytics, ML, and customer-facing data products.
Top Skills: AirflowAmundsenSparkAws RdsCloudFormationDagsterDatabricksDatahubDelta LakeDockerDynamoDBEcsFargateGoHive MetastoreHudiIcebergJavaKinesisKubernetesLambdaPrefectPythonS3ScalaSqsTerraformUnity Catalog
7 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
218K-257K Annually
Senior level
218K-257K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Lead architecture and technical direction for Payments platform, building scalable, fault-tolerant distributed systems, defining roadmaps, ownership of production reliability, cross-functional partnership, and mentoring engineers to improve platform quality and scalability.
Top Skills: APIsDistributed SystemsGenerative AiMulti-Tenant ArchitectureObservabilityPayment SystemsSlos
Reposted 7 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
218K-257K Annually
Senior level
218K-257K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
The role involves owning the architecture and technical direction of Payment Rails infrastructure, designing high-reliability systems for global payment processing, and leading cross-functional collaborations to create efficient, compliant solutions. Responsibilities also include mentoring team members and enhancing operational excellence through AI-driven improvements.
Top Skills: Ai ToolsApi DesignBlockchain TechnologyDistributed SystemsFinancial InfrastructurePayment Gateways
Reposted YesterdaySaved
Remote
St. Louis, MO
Senior level
Senior level
Software • Cryptocurrency
Lead the design and implementation of core authentication infrastructure at Phantom, focusing on secure authentication systems, secrets management, and API integrations.
Top Skills: Aws KmsNestjsNode.jsOauth2OidcRustTypescriptVaultWebauthn
Reposted YesterdaySaved
Remote
St. Louis, MO
200K-250K Annually
Senior level
200K-250K Annually
Senior level
Software • Cryptocurrency
As a Software Engineer, you'll develop trading APIs and systems, enhance user experiences, and lead initiatives for blockchain support and new products.
Top Skills: APIsBlockchainCrypto Trading SystemsData Pipelines
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Reposted YesterdaySaved
Remote
St. Louis, MO
125K-190K Annually
Senior level
125K-190K Annually
Senior level
Fintech
As a Software Engineer at OnePay, you will develop and implement features, build scalable products, and work closely with teams to enhance customer experiences.
Top Skills: AWSFp-TsKubernetesNode.jsTypescript
Reposted YesterdaySaved
Remote
St. Louis, MO
Senior level
Senior level
Fintech • Payments • Software • Financial Services
Join Aleph's engineering team to develop the Core Product, focusing on user-facing features for financial data insights. Collaborate with leadership, design robust software components, and contribute to system architecture in a fast-paced, remote environment.
Top Skills: BigQueryGCPJavaScriptMongoDBNode.jsPythonReactTypescript
Reposted YesterdaySaved
Remote or Hybrid
St. Louis, MO
142K-265K Annually
Senior level
142K-265K Annually
Senior level
3D Printing • Aerospace • Hardware • Robotics • Software
As a Backend Software Engineer, you'll design, develop, and optimize scalable backend platforms and services while collaborating with cross-functional teams.
Top Skills: AWSAzureCi/CdGCPReal-Time Data PlatformsServerless Architecture
Reposted YesterdaySaved
Remote or Hybrid
St. Louis, MO
143K-250K Annually
Senior level
143K-250K Annually
Senior level
3D Printing • Aerospace • Hardware • Robotics • Software
Develop and improve real-time drone tele-operations features, cloud-based products, and quickly prototype new front-end experiences while transitioning to a new tech stack.
Top Skills: Cloud-Based ProductsData VisualizationReactUdpWebsockets
Reposted YesterdaySaved
Remote or Hybrid
St. Louis, MO
142K-250K Annually
Senior level
142K-250K Annually
Senior level
3D Printing • Aerospace • Hardware • Robotics • Software
Develop and deploy life-saving technologies as a fullstack engineer, focusing on web applications for public safety, collaborating with various engineering disciplines and leveraging customer feedback.
Top Skills: Google MapsJavaScriptLampMapboxMeanMernNode.jsNoSQLRtspServerlessSQLWebrtc
Reposted YesterdaySaved
St. Louis, MO
Senior level
Senior level
AdTech • Fintech • Information Technology • Database
Design and implement high-performance system software for medical devices, collaborating with hardware engineers and ensuring adherence to clinical standards.
Top Skills: C++Python
Reposted YesterdaySaved
St. Louis, MO
Senior level
Senior level
AdTech • Fintech • Information Technology • Database
The Principal Desktop UI Software Engineer will design and develop user-friendly interfaces for medical devices, collaborating with cross-functional teams and mentoring junior members.
Top Skills: AWSAzureC++GitLinuxOpen GlPythonQmlQtRos
Reposted YesterdaySaved
Remote
St. Louis, MO
142K-208K Annually
Senior level
142K-208K Annually
Senior level
Productivity • Software • Conversational AI
As a Senior Software Engineer, you will build backend APIs for authentication and authorization, partner with leadership, and mentor other engineers while improving production quality.
Top Skills: DynamoDBGoRestful ApiTypescript
Reposted YesterdaySaved
Remote
St. Louis, MO
Senior level
Senior level
Software
This role involves building and maintaining production-grade web applications using React and Next.js and developing cross-platform mobile features with React Native, while mentoring others and influencing technical direction.
Top Skills: Next.JsNode.jsReactReact NativeTypescript
Reposted YesterdaySaved
Remote
St. Louis, MO
Senior level
Senior level
Software
As a Senior Software Engineer, you'll develop AI-powered tools, manage complex databases, optimize application performance, and lead technical decisions.
Top Skills: AWSDockerGitGithub ActionsPostgresPython
Reposted 16 Days AgoSaved
In-Office
St. Louis, MO
133K-155K Annually
Senior level
133K-155K Annually
Senior level
Aerospace • Information Technology • Software • Cybersecurity • Design • Defense • Manufacturing
The Senior Software Engineer will design, develop, test, and maintain software for the Tomahawk Missile program, implement automation processes, and ensure compliance with safety standards and regulations.
Top Skills: AnsibleAzure DevopsCi/CdInfrastructure As CodeJIRALinuxMicroservicesRestful ApisWindows 10Windows 11Windows Server
8 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
186K-219K Annually
Senior level
186K-219K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Build and improve frontend experiences for login, signup, OAuth, account security, and multi-user/org support. Contribute to migrating main views to React Native, design high-performance React/TypeScript UIs, collaborate with backend engineers and product teams, and write well-tested, reliable code to maintain low-latency user surfaces at scale.
Top Skills: GeminiGleanLibrechatMulti-Factor AuthenticationOauthReactTypescript
8 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
218K-257K Annually
Senior level
218K-257K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Lead architecture and delivery of Control Center platform capabilities (MCP tool registries, AI orchestration, access automation). Design agentic AI integrations, HITL workflows, and evaluation/guardrail frameworks. Own backend services, SLOs, observability, incident response, and operational readiness for Tier-1 systems. Drive cross-team technical direction, author TDDs, run design reviews, mentor engineers, and partner with Product and Security to deliver secure, scalable platform primitives.
Top Skills: AWSCi/CdGoGraphQLGrpcHitlKafkaKubernetesLlm OrchestrationMcpMemcachedMqNoSQLPythonRagRedisSQLTerraform
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