Top Senior Software Engineer Jobs in St. Louis, MO

The Staff SDET will design and implement automated test frameworks using TypeScript, collaborate with developers, and enhance testing processes within CI/CD pipelines.

The Senior Software Engineer will enhance the core product by developing features and tools for Chainguard Images, collaborating with teams and ensuring product quality.

Develop core backend components for a blockchain network, focusing on reliability and scalability, mainly using Rust. Ensure code quality through testing and debugging.

Provide technical and architectural leadership to the software development team, design software solutions, mentor team members, and drive projects to completion.

The Senior Software Engineer will collaborate with teams to build and optimize a robust web application, ensure code quality, and elevate team impact.

The Staff Software Engineer will develop full stack solutions, contribute to architecture, mentor junior developers, and collaborate with teams on software projects.

Owner of full-stack features and platform reliability: build scalable web applications, optimize PostgreSQL performance, maintain asynchronous infrastructure (Celery), migrate frontend to server-side HTMX, ship revenue-driving features, ensure observability and SLO-driven reliability, collaborate cross-functionally, write testable code, and participate in architecture and code reviews.

The Senior Software Engineer will develop and maintain big data applications, focusing on distributed computing, automation, and collaboration with teams to enhance healthcare solutions.

Build and harden product features and tooling for AWS GovCloud, ensuring security, auditability, and compliance. Implement GovCloud-specific authentication, logging, observability, and developer tooling; analyze and remediate security gaps; mentor engineers; support federal self-hosted customers and on-call escalations.

Design and implement backend services for an AI-driven automation platform, focusing on LLM orchestration, API development, and system reliability.

Design and implement automated quality systems for disaster recovery and production environments, enhancing reliability through automation and intelligent diagnostics, while collaborating with QA and engineering teams.

Design and build applications using Python, manage component design, optimize performance, and collaborate with clients on innovative products.

Design and implement integrations for a B2B platform, focusing on ERP systems and API architectures while providing technical leadership.

Develop and maintain calibration, automation, and tooling software for quantum processors. Design and implement front-end and back-end systems, APIs, and databases; troubleshoot performance issues; collaborate with scientists and engineers; and mentor junior engineers.

Design, develop, test, and deploy features for the EverHealth platform. Troubleshoot and debug, review PRs, expand unit test coverage, participate in agile ceremonies, and maintain application performance and observability.

Lead architecture and scaling of cloud-native infrastructure to support large AI workloads. Mentor engineers, decompose complex systems, design foundational platform services, and collaborate with product, research, and security teams to ensure secure, performant, and highly available GPU/ML infrastructure.

Technical leader for Platform & Infrastructure building scalable, resilient cloud-native systems to support large AI workloads. Define architecture, mentor engineers, solve systemic infrastructure bottlenecks, design foundational platform services, and collaborate cross-functionally to ensure secure, high-performance operations.

Design, build, and optimize GraphQL APIs, gRPC services and SQL queries for a promotions engine. Own complex technical problems, improve production scalability and performance, set up DataDog monitoring, participate in on-call rotations, mentor engineers, and deliver end-to-end features in an agile environment.

Own architecture, development, and reliability of ecommerce web applications (Symfony storefront and Laravel back-office). Lead front-end JavaScript/CSS direction, optimize SQL schemas/queries, improve observability and incident response, reduce legacy technical debt, establish AI-assisted development workflows, mentor engineers, and drive end-to-end delivery of scalable customer-facing features.

Build and ship full‑stack product features on a Python/Flask backend and React frontend. Design REST/GraphQL APIs, work with SQLAlchemy and relational data models, integrate LLM/AI features, use async task queues (Celery), and collaborate with product, design, and engineers to deliver reliable, well-tested features end-to-end.

Design, build, and architect stablecoin and crypto infrastructure; integrate DEXs, DeFi protocols, and wallet providers; develop smart contract interactions; expand crypto product functionality and asset selection; collaborate cross-functionally; establish crypto development standards and ensure security and reliability for large-scale user experiences.

Build and operate AlphaSense's identity platform across user management, authentication, and authorization. Design scalable RBAC/ABAC/ReBAC systems, integrate authentication patterns (OAuth/OIDC/SAML), implement SCIM provisioning, and expose GraphQL/gRPC/REST APIs. Partner with security on SOC2/GDPR compliance, drive platform roadmap, champion testing, observability, and reliability, and operate autonomously from North America in close collaboration with the Helsinki team.

Design, build, and operate high-performance Places/Search API services; drive architecture and scalability decisions; improve code quality and operational standards; mentor engineers; run experiments and telemetry-driven analysis; participate in feature delivery, on-call rotation, and customer-facing collaboration with automotive and mapping partners.

Design, implement, and maintain scalable Java-based software solutions. Collaborate across the SDLC with stakeholders and development teams, integrate DevOps and CI/CD practices, support operational tasks, ensure security and performance, drive feature development, conduct code reviews, and stay current with emerging technologies.

The Senior Software Engineer will modernize USPS shipping technology, refactor legacy systems for cloud integration, and develop high-performance services using Go, while collaborating with teams and addressing production challenges.