Top Senior Machine Learning Jobs in St. Louis, MO

Lead end-to-end healthcare analytics projects, managing scope, planning, execution, client relationships, cross-functional collaboration, risks, and delivery. Provide thought leadership in healthcare analytics and identify business opportunities within client accounts. Required capabilities include quantitative analysis, project management, communication, presentation, SQL/Python/R proficiency, and strategic use of AI tools. Preferred experience includes consulting, cloud analytics platforms, healthcare data regulations, predictive modeling, machine learning, and data visualization.

Leads architecture and development of production-grade mapping and localization ML systems for autonomous vehicles. Designs neural models for detection, segmentation, tracking, depth estimation, 3D reconstruction, and semantic mapping; owns data strategy, evaluation, deployment, and fleet validation. Mentors engineers, drives technical roadmaps, collaborates cross-functionally, and advances vectorized HD mapping, foundation models, and real-time optimization.

Own end-to-end design for complex financial product experiences from exploration through launch and iteration. Translate financial workflows into intuitive customer experiences, set high standards for interaction and visual design, partner with product and engineering, use research and data to guide decisions, contribute to design systems, present work clearly, and mentor teammates. Apply AI-enabled tools thoughtfully while maintaining strong human-centered judgment.

Leads an engineering team building and scaling customer-facing integrations for agentic AI products. Responsibilities include setting technical direction, balancing customer delivery with reusable tooling and platform investments, ensuring reliability and observability, improving developer experience, collaborating cross-functionally, recruiting, and coaching engineers. The role requires customer empathy, strong engineering leadership, technical problem-solving, and experience with production systems or integrations.

Lead research and experimentation to measure ad campaign performance and effectiveness. Design evaluation frameworks, build measurement solutions, develop models for lift, conversion, and attribution, run experiments and analyses, partner with product/engineering/design/sales, present insights, mentor teammates, and foster technical community and culture.

Build and operate scalable, highly available ML/LLM serving and compute infrastructure. Own long-term platform vision, deliver zero-to-one projects, partner cross-functionally, optimize performance and capacity, and support production ML models at scale.

Lead design and execution of scalable experimentation frameworks for Netflix Ads. Develop auction-based, biddable media models, solve cold-start measurement problems globally, apply causal inference and ML, partner with product and engineering, and translate analytic results into strategic recommendations to optimize marketplace dynamics and member experience.

Design, productionize, and deploy machine learning forecasting models for ad inventory and campaign performance in low-latency, real-time advertising environments. Build scalable simulation, budgeting, and pacing systems; collaborate with cross-functional teams to deploy models at scale and optimize ad monetization.

Lead design, execution, and optimization of scaled lifecycle campaigns across email and in-product channels. Use marketing automation, behavioral data, and ML techniques to personalize journeys, drive activation, revenue, retention, and cross-sell. Analyze performance, generate insights, and collaborate with Growth, Product, Engineering, Data Science, Analytics, Sales, and Marketing stakeholders.

Lead design, execution, and interpretation of A/B tests and quasi-experiments; apply causal inference methods; partner with product, engineering, and marketing; mentor data scientists; build experimentation frameworks; extract and analyze data using SQL and Python; communicate results to stakeholders.

The Senior Product Manager will set product direction, own the development lifecycle, collaborate with teams, and ensure high-quality outputs. This role requires strong opinions on product quality and customer insights.

The Enterprise Account Executive drives revenue through high-value contracts, managing complex sales processes and relationships with executive stakeholders in financial services.

Lead the Decision Science function, designing ML models, overseeing experimentation frameworks, and ensuring model adoption across the company, driving operational and commercial improvements.

Lead and build a team that drafts and submits state-specific rating rules, underwriting guidelines, and forms; manage filing execution via SERFF, handle objection responses, coordinate cross-functional stakeholders, establish operating rhythms, improve documentation and controls, and coach staff to scale filing expertise and regulatory execution.

Author and verify rigorous multiple-choice computer science assessment items across many CS domains to create gold-standard benchmarks for AI research. Produce correct answers, nine plausible distractors, solution explanations, difficulty labels, and authoritative references. Review and edit questions for technical accuracy, clarity, and reproducibility. Contribute asynchronously as an independent contractor, ~10+ hours/week, fully remote.

Lead design and build of a cloud-based big data analytics platform: implement analytics infrastructure, integrate streaming and batch data, develop distributed processing pipelines, manage predictive analytics models, and apply machine learning and Bayesian methods. Work involves Scala on OS X and AWS, Java and Clojure, Kafka/Samza, NoSQL, and following TDD, Agile, CI/CD practices.

Design, automate, and secure geospatial data ingestion, processing, and dissemination for NGA MC&G. Build APIs, maintain Python codebases, implement ETL and database security, integrate CI/CD and IaC security, and collaborate with GEOINT teams to enforce data integrity and quality checks.

Serve as primary client contact for a portfolio of loyalty-program clients. Scope and manage end-to-end actuarial analyses rooted in predictive modeling and machine learning, validate model outputs, translate results into clear recommendations and presentations, and partner with analysts and data scientists to deliver high-quality, client-facing work in a fully remote consulting environment.

Partner with a retained search firm to place software engineers and quant developers at top hedge funds. Provide candidate flow from your network; firm supplies clients, process, and fees. Remote, commission-only role with placement and pipeline incentives. Apply with placement examples, outreach metrics, and a candidate submission.

Lead and align ML, data, and engineering teams to define multi-year AI roadmaps, deliver production ML solutions, ensure robust data pipelines, set success metrics tied to business outcomes, and grow/mentor senior managers and engineers.

Lead and build a data science organization to create a prediction engine for vendor matching, order routing, and supply chain optimization. Anchor projects to P&L, design measurement and experiment frameworks, ship rapid wins, hire and coach data scientists, work hands-on in modeling and technical design, partner with product and engineering (Snowflake), and evolve systems toward agentic AI while reporting impact in dollar terms.

Build, ship, and own end-to-end ML models for vendor matching, order routing, and supply-chain optimization. Partner with data engineering to productionize models, quantify impact, document work, and implement decision logic components toward agentic AI in a fast-moving healthcare startup environment.

Own end-to-end modeling for vendor matching, order routing, and supply-chain optimization. Build predictive, causal, RL and OR solutions; design autonomous decision logic; quantify counterfactual impact; ship production models with data engineering; mentor senior data scientists; write technical design docs; partner on quarterly priorities and expand into revenue cycle and finance domains.

The Staff Product Manager will define product strategy, lead the product lifecycle, collaborate across teams, and drive innovation in claims processing software.

Lead procurement strategy and supplier selection for inbound products and services. Manage RFIs/RFPs, negotiate contracts with Legal, administer Coupa purchase orders, reconcile invoices, and apply AI/ML and reporting tools to optimize procurement processes while collaborating with cross-functional senior stakeholders.