Top Senior IT Jobs in San Antonio, TX

Reposted 22 Days AgoSaved
Remote
San Antonio, TX
Senior level
Senior level
Healthtech
The Senior IT Project Manager oversees the delivery of technology and business transformation projects, supports PMO standards, manages project risks, and mentors junior managers.
Top Skills: JIRAMs ProjectServicenow PpmSmartsheet
Reposted 22 Days AgoSaved
Remote or Hybrid
San Antonio, TX
138K-190K Annually
Senior level
138K-190K Annually
Senior level
Artificial Intelligence • Healthtech • Social Impact • Telehealth
Build and maintain internal platforms, automations, and integrations to scale IT operations. Own identity, access, lifecycle automation, endpoint trust, SaaS provisioning, and operational reporting. Develop scripts and services (Python, Bash), partner with Security and Engineering for secure AI, Zero Trust, HIPAA and SOC 2 compliance, and apply DevOps/SRE/ITIL practices for monitoring and incident response.
Top Skills: AWSBashCi/CdGitGitGithub ActionsGoogle WorkspaceIamIpaasJamf ProJSONLambdaLinuxMicrosoft 365Microsoft IntuneOktaOkta WorkflowsPythonRest ApisWebhooksWorkato
Reposted 22 Days AgoSaved
In-Office or Remote
San Antonio, TX
133K-259K Annually
Senior level
133K-259K Annually
Senior level
Semiconductor • Manufacturing
The M&A Lead Integration Architect will strategize and implement integration plans for acquired entities, collaborating with various teams to ensure seamless transitions and alignment with business goals.
Top Skills: CRMErpHris
23 Days AgoSaved
In-Office or Remote
San Antonio, TX
36K-128K Annually
Senior level
36K-128K Annually
Senior level
Agency • Information Technology
Lead planning, execution, and delivery of enterprise technology projects. Manage scope, timelines, budgets, resources, risks, vendors, and stakeholder communications across Agile, Scrum, and Waterfall environments. Oversee software development, technology implementations, cloud transformation, application modernization, and other enterprise initiatives while coordinating cross-functional teams and multiple concurrent priorities.
Top Skills: AgileApplication ModernizationCloud TransformationScrumSdlcWaterfall
Reposted 23 Days AgoSaved
Remote
San Antonio, TX
Senior level
Senior level
Artificial Intelligence • Healthtech • Software • Telehealth
Lead global IT operations for a HIPAA-regulated healthtech company, managing a small support team and hands-on ticketing. Build and maintain systems for compliance and visibility, optimize vendor costs, implement security/onboarding processes, drive process improvements with KPIs and automation, and serve as primary IT liaison to leadership and partners.
Top Skills: Google WorkspaceJAMFJIRAOktaSaaS
Reposted 24 Days AgoSaved
Remote
San Antonio, TX
94K-115K Annually
Senior level
94K-115K Annually
Senior level
Cloud • Information Technology • Productivity • Security • Software
Serve as IT Infrastructure Project Manager for public sector clients, delivering networking, wireless, UC, and data center/security projects on time and within budget. Manage schedules, budgets, vendors, stakeholders, risks, QA, and multiple concurrent projects. Provide client-facing communication, financial reporting, and leadership of internal and external teams while ensuring project profitability and adherence to methodology.
Top Skills: Data CenterNetworkingProject Management SoftwareSecurityUnified CommunicationWireless
Reposted 24 Days AgoSaved
Remote
San Antonio, TX
169K-233K Annually
Senior level
169K-233K Annually
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Marketing Tech • Software • Biotech • Design
Lead a global IT support team, drive AI-first ITSM transformation (ServiceNow->Atomicwork), own ITSM processes and SLA governance, partner on JML/identity automation with Platform Engineering, manage vendors, run cross-functional programs, develop regional specialists, and participate in on-call escalations. Position requires East Coast timezone alignment and ~25% international travel.
Top Skills: Ai-Native ItsmAtomicworkConfluenceConsoleJIRAJsmOktaServicenowSlack
24 Days AgoSaved
Remote
San Antonio, TX
Senior level
Senior level
Transportation • Energy • Utilities • Industrial
Drive national sales and account growth for IT cooling equipment, services, and software. Develop strategic customer relationships, pursue new business, manage channel partners, lead proposals and negotiations, forecast revenue, analyze market trends, and represent the company at industry events. The role requires technical knowledge of HVAC, mission-critical infrastructure, power quality, and data center solutions, along with strong commercial, communication, and relationship-management skills.
Top Skills: Critical PowerData Center InfrastructureHvacIt CoolingMS OfficePower QualitySalesforce
Reposted 24 Days AgoSaved
Remote
San Antonio, TX
70K-80K Annually
Senior level
70K-80K Annually
Senior level
Healthtech
Provide frontline and advanced application support for radiology imaging workflows: incident triage, user provisioning, configuration changes, DICOM troubleshooting, monitoring interfaces, coordinating with networks/storage/vendors, maintaining SOPs and knowledge base, delivering end‑user training and on‑call doctor support to meet SLAs.
Top Skills: DicomDicom TracesHipaaImaging ViewerItsm/TicketingModalityNetworkingPacsStorageWorklist
Reposted 24 Days AgoSaved
In-Office or Remote
San Antonio, TX
Senior level
Senior level
Events • Gaming • News + Entertainment • Other
Lead end-to-end IT sourcing for hardware, software, SaaS, and security services. Develop sourcing strategies, run RFx and negotiations, draft and manage contracts, perform market and TCO analysis, mitigate risks, manage supplier performance, and align cross-functional stakeholders to optimize cost, performance, and vendor portfolios.
Top Skills: Collaboration ToolsContract Management SoftwareEnterprise SecurityNetworking HardwareProductivity SoftwareSaaS
Reposted One Month AgoSaved
In-Office
San Antonio, TX
30-41 Hourly
Senior level
30-41 Hourly
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Provide frontline IT support via phone, email, chat and ticketing systems. Troubleshoot hardware, software, printers, scanners and peripherals; perform account management tasks, installs/updates, inventory and documentation. Escalate complex issues, mentor junior staff, follow security policies, contribute to knowledge base, and maintain mission-essential availability for onsite support.
Top Skills: Hardware TroubleshootingPeripheralsPrintersRemote Support ToolsScannersSoftware TroubleshootingTicketing Systems
25 Days AgoSaved
Remote
San Antonio, TX
128K-173K Annually
Senior level
128K-173K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Design and develop scalable cloud applications using Node.js, microservices, Azure, and AWS. Build workflow, data integration, REST API, serverless, and event-driven solutions; integrate client applications with cloud storage; implement security, testing, CI/CD, and DevSecOps practices. Optimize performance and cost, collaborate with cross-functional teams, provide technical leadership and mentorship, conduct technology research, and communicate architecture and recommendations to stakeholders.
Top Skills: AgileAWSAzureAzure FunctionsCi/CdCosmos DbDatabricksDevsecopsDockerDocumentdbETLGCPGitKubernetesMicroservicesNode.jsOauth 2.0OcpReactRestful ApisSnowflakeSQLSwagger
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Reposted 25 Days AgoSaved
Remote
San Antonio, TX
Senior level
Senior level
Big Data • Software
Deploy and maintain AI enablement infrastructure (MCP servers, AI agents, AI features in SaaS), manage service accounts and API keys, automate and containerize services, support enterprise IT systems, document integrations and runbooks, and mentor IT support staff.
Top Skills: Ai AgentsAnthropicAPIsAtlassian RovoAWSBashChatgptDockerGitGCPGoogle GeminiJSONMcpMcp ServersOauthOktaOkta AiPythonSlack AiSsoYaml
26 Days AgoSaved
Remote
San Antonio, TX
Senior level
Senior level
Healthtech • Software
Owns the company-wide IT and cybersecurity program, including SOC 2 compliance, cloud security, penetration-test remediation, business continuity testing, endpoint management, access controls, onboarding and offboarding, AI security governance, vendor reviews, security training, incident response, and employee IT support. The role partners with engineering, HR, Finance, leadership, auditors, and healthcare customers while managing security across AWS, Heroku, Cloudflare, Google Workspace, GitHub, and related tools.
Top Skills: 2FaAWSClaudeCloudflareCspmEdrGitGoogle WorkspaceGrcHerokuIamMcp ServersMdmRipplingSIEMSoc 2SsoVantaXdr
26 Days AgoSaved
Remote
San Antonio, TX
143K-167K Annually
Senior level
143K-167K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Lead and manage a technical database team supporting Oracle and Microsoft SQL Server and middleware (WebLogic) across on‑prem and cloud. Oversee daily operations, service delivery, cloud migrations, incident response, people management, project execution, and continuous improvement while ensuring stakeholder engagement and modernization of services.
Top Skills: AgileAICloudItilMicrosoft Sql ServerOracleRhelSun SolarisUnixWeblogic
Reposted 26 Days AgoSaved
Remote
San Antonio, TX
94K-115K Annually
Senior level
94K-115K Annually
Senior level
Big Data • Cloud • Hardware • Software • App development
Manage multiple public-sector IT infrastructure projects end-to-end, ensuring on-time, on-budget delivery. Lead stakeholders, vendors, and internal teams; build schedules, manage risks, finances, QA, and client communications for networking, wireless, and unified communications engagements.
Top Skills: Data CenterNetworkingProject Management SoftwareSecurityUnified CommunicationWireless
27 Days AgoSaved
Remote
San Antonio, TX
Senior level
Senior level
Healthtech
Lead assessment and remediation of IT security risks across network, systems, and applications. Perform vulnerability assessments, manage IDS/IPS, coordinate remediation with IT and vendors, develop policies and training, support audits (SOX/PCI/HIPAA), and report findings to stakeholders while mentoring teams and guiding security projects.
Top Skills: HipaaIntrusion Detection/Prevention (Ids/Ips)Microsoft Windows EnterpriseNist Cybersecurity FrameworkPciSoxVulnerability Management Tools
27 Days AgoSaved
Remote
San Antonio, TX
160K-175K Annually
Senior level
160K-175K Annually
Senior level
Artificial Intelligence • Healthtech • Software • Telehealth
Lead Fabric's security program and corporate IT operations, including identity, endpoint, cloud, application, and vendor security. Hire and manage a small team, run incident response, handle customer security questionnaires, partner on SOC2/HITRUST/HIPAA control implementation, and set practical security policy while remaining hands-on in operations and tooling.
Top Skills: AWSEndpoint ManagementGCPHipaaHitrustIamMdmNist 800-66OktaSaas ProvisioningSoc2Sso
27 Days AgoSaved
Remote
San Antonio, TX
125K-155K Annually
Senior level
125K-155K Annually
Senior level
Artificial Intelligence • Machine Learning • Social Impact • Analytics
Own and operate the organisation's accounts, access, and cloud subscriptions; set practical security standards; identify and remediate risks hands-on; manage onboarding/offboarding access across core platforms; partner with engineers and researchers to ensure secure, usable controls.
Top Skills: 1Password2FaAirtableAWSGitGCPGoogle WorkspaceIamSlack
27 Days AgoSaved
Remote
San Antonio, TX
135K-155K Annually
Senior level
135K-155K Annually
Senior level
Insurance
Lead end-to-end IT risk-based audits, test ITGCs and key IT risks, manage continuous audit testing, support external audits, advise on new technologies (cloud, AI, cybersecurity), communicate findings to leadership, and lead team development and advisory projects across the enterprise.
Top Skills: AICloud ComputingCybersecurityData AnalyticsNetworking
27 Days AgoSaved
In-Office or Remote
San Antonio, TX
Senior level
Senior level
Financial Services
Lead design, deploy, operate, and maintain endpoint security solutions (CrowdStrike, Skyhigh, Symantec DLP, Zscaler). Monitor telemetry into SIEM/SOAR, perform upgrades/migrations, troubleshoot detections, drive automation, evaluation of new tech, and maintain documentation to strengthen endpoint security posture.
Top Skills: APIsAWSAzureCrowdstrike EdrCrowdstrike FalconCrowdstrike FirewallCrowdstrike Identity ProtectionCrowdstrike NgavEntra IdFalcon For MobileIcapInfrastructure-As-CodeLinuxmacOSProxyScriptingSIEMSkyhigh Web GatewaysSoarSymantec Dlp PreventTlsVdiWindowsZscaler
27 Days AgoSaved
In-Office or Remote
San Antonio, TX
90K-115K Annually
Senior level
90K-115K Annually
Senior level
Insurance
Develop, implement, and maintain security policies and controls mapped to NIST CSF; manage policy and compliance workflows in ServiceNow IRM; perform risk assessments and gap analyses; support audit readiness and vendor assessments; produce dashboards and reports; lead security awareness and AI governance training; mentor junior analysts; collaborate with IT, risk, compliance, and business teams to drive remediation and policy adoption.
Top Skills: AWSAzureCisGCPIso 27001Knowbe4Nist CsfSaaSServicenowServicenow IrmSoc 2
27 Days AgoSaved
Remote
San Antonio, TX
Senior level
Senior level
Healthtech • Social Impact
Manage and execute RCA's cybersecurity program: lead audits and vendor risk assessments, run security awareness/phishing programs, oversee vulnerability remediation and MDM, ensure HIPAA/HITECH/NIST compliance, build security reporting, and coordinate incident response and tabletop exercises.
Top Skills: CrowdstrikeGrc PlatformsKnowbe4MdmMicrosoft 365 Security SuiteMicrosoft IntuneSIEMVendor Risk ToolsVulnerability Management Solutions
27 Days AgoSaved
Remote
San Antonio, TX
120K-170K Annually
Senior level
120K-170K Annually
Senior level
Healthtech • On-Demand • Software • Telehealth
Lead enterprise cybersecurity and IT operations for a HIPAA-regulated healthcare company: build and mature security programs, manage IAM/endpoint/cloud security, drive vulnerability management and incident response, ensure compliance (HIPAA/HITECH), oversee IT operations and vendor risk, and mentor a technical team while partnering with cross-functional leadership.
Top Skills: AWSAzureBackupDisaster RecoveryEndpoint ManagementEnterprise Saas AdministrationGCPHipaaHitechIamIncident ResponseMdmMfaPenetration TestingPrivileged Access ManagementSsoVulnerability Management
27 Days AgoSaved
Remote
San Antonio, TX
130K-173K Annually
Senior level
130K-173K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Support ATO documentation and assessment for a cloud-based federal courts modernization program. Coordinate with security, engineering, and PM teams; create Visio diagrams; monitor, test, and troubleshoot IA issues; analyze CND/SIEM logs; assess configurations; implement enterprise security policies and procedures; manage vulnerability tracking and incident documentation; provide AWS cloud security expertise and ensure compliance with NIST, FedRAMP, CIS, and ISO 27001.
Top Skills: AWSAws Cloud SecurityCisComputer Network Defense (Cnd) ToolsCsamFedrampFirewallIcamIso 27001Microsoft VisioNetwork Traffic LogsNistSIEMVulnerability Management
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