Top Senior IT Jobs in San Antonio, TX

Reposted 10 Days AgoSaved
Remote
San Antonio, TX
Senior level
Senior level
Fintech • Software • Financial Services
The Manager of Internal Audit (IT) leads audit engagements, supervises staff, and develops risk-based audit schedules while ensuring compliance with regulatory standards.
Top Skills: Bank AuditCobitComputer Assisted Audit TechniquesData AnalyticsIt AuditIt General ControlsNist
Reposted 10 Days AgoSaved
Remote
San Antonio, TX
140K-150K Annually
Senior level
140K-150K Annually
Senior level
Healthtech • Pharmaceutical
The IT Systems Engineer III will improve Ophelia's IT systems through integration, automation, and security while managing IT projects, overseeing service providers, and ensuring compliance.
Top Skills: AIDlpDns AdministrationEdrGoogle Cloud PlatformIdp/IamItsmMdmSAMLScimZtna
Reposted 10 Days AgoSaved
Remote
San Antonio, TX
190K-215K Annually
Senior level
190K-215K Annually
Senior level
Biotech
The Director of IT Business Enablement will lead partnerships with manufacturing leaders to drive technology strategies, optimize processes, and promote operational excellence across the organization.
Top Skills: ErpLimsManufacturing Execution Systems
Reposted 10 Days AgoSaved
Remote
San Antonio, TX
190K-215K Annually
Senior level
190K-215K Annually
Senior level
Healthtech
Lead global IT business enablement for Manufacturing and Quality, forging partnerships, driving innovation, and ensuring operational excellence through technology.
Top Skills: Advanced AnalyticsAutomationDigital TechnologiesErpLimsManufacturing Execution Systems
Reposted 10 Days AgoSaved
Remote
San Antonio, TX
190K-215K Annually
Senior level
190K-215K Annually
Senior level
Healthtech • Other • Software • Biotech
The role leads IT Business Enablement, partnering with senior leaders to drive operational excellence in Manufacturing and Quality through technology and agile practices.
Top Skills: ErpLimsManufacturing Execution Systems
Reposted 10 Days AgoSaved
Remote
San Antonio, TX
161K-350K Annually
Senior level
161K-350K Annually
Senior level
AdTech • Digital Media • Information Technology • Other
The role involves designing and developing enterprise-grade software solutions, integrating AI tools, collaborating with teams, and maintaining documentation while enhancing productivity for Yahoo personnel.
Top Skills: AWSDockerGCPJavaKubernetesPython
Reposted 11 Days AgoSaved
Remote
San Antonio, TX
125K-175K Annually
Senior level
125K-175K Annually
Senior level
Insurance
The Director of IT Applications leads the delivery of enterprise applications, ensuring that business systems effectively support operations across Finance, Sales, Marketing, HR, and more while driving automation and system improvements.
Top Skills: ConfluenceJIRAOracle NetsuiteSalesforceServicenow
Reposted 11 Days AgoSaved
In-Office or Remote
San Antonio, TX
Senior level
Senior level
Blockchain • Fintech • Software • Financial Services • Cryptocurrency
Lead IT support operations, ensuring high-quality technical support, vendor management, and IT processes for a remote workforce while improving contributor experience.
Top Skills: APIsDnsIt Administration ToolsSaas SolutionsVpns
Reposted 11 Days AgoSaved
Remote
San Antonio, TX
135K-165K Annually
Senior level
135K-165K Annually
Senior level
Machine Learning • Productivity • Sales • Software
The Senior Manager of Corporate Operations will lead technical strategy for internal systems, focusing on IAM, MDM, and corporate infrastructure, ensuring security and operational excellence across environments.
Top Skills: APIsBashGoogle WorkspaceIntuneJAMFMerakiMicrosoft O365Mobile Device ManagementOktaPythonVerkada
Reposted 12 Days AgoSaved
Remote
San Antonio, TX
105K-179K Annually
Senior level
105K-179K Annually
Senior level
Healthtech • Pharmaceutical
The Lead IT Telecom Architect designs and optimizes Telecom and Contact Center architecture to meet business goals, ensuring security and performance. Responsibilities include strategy development, technology evaluation, system implementation oversight, and stakeholder collaboration.
Top Skills: AWSCcaasCloud ServicesUcaasVoip
13 Days AgoSaved
Remote
San Antonio, TX
137K-171K Annually
Senior level
137K-171K Annually
Senior level
Marketing Tech
Lead design, implementation, and administration of enterprise IT infrastructure with a strong focus on identity and access management across GCP, AWS, and GitHub. Build Okta-driven provisioning workflows, automate processes, manage IAM governance and compliance, support IT support escalations, and evolve security policies including PAM and EDR controls.
Top Skills: Aws IamBashBeyondtrustCloudFormationCyberarkEdrExcelFederated AccessGcp Iam (Cloud Identity)Github EnterpriseGoogle SheetsIam Identity CenterIntuneJAMFOktaOkta WorkflowsPythonSAMLScimSsoTerraformWorkato
Reposted 13 Days AgoSaved
Remote
San Antonio, TX
Senior level
Senior level
Financial Services
The Senior Technology Specialist oversees the design and support of technology solutions, ensuring they meet business needs and compliance standards, while mentoring junior staff and optimizing operations.
Top Skills: AutomationAWSEnterprise ApplicationsMicrosoft 365AzureScriptingSecurity TechnologiesVirtualization
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Reposted 24 Days AgoSaved
In-Office
San Antonio, TX
138K-207K Annually
Senior level
138K-207K Annually
Senior level
Energy
Lead IT Manager for Data Operations and Platforms, responsible for strategy, development, and management of data products and analytics platforms, overseeing team performance and ensuring compliance with security standards.
Top Skills: AIAzure SynapseCogniteDatabricksDevOpsKnowledge Graph DatabasesMlMlopsMs PurviewPower BIRpa
Reposted 14 Days AgoSaved
Remote
San Antonio, TX
80K-120K Annually
Senior level
80K-120K Annually
Senior level
Artificial Intelligence • Information Technology • Consulting
The Business Development Manager will focus on acquiring new clients and expanding accounts within the IT staffing sector, managing the full sales cycle and meeting revenue targets.
Top Skills: It StaffingMspVms
15 Days AgoSaved
Remote
San Antonio, TX
Senior level
Senior level
Healthtech • Information Technology • Professional Services • Consulting
Lead design, implementation, and optimization of ServiceNow ITOM (Discovery, Service Mapping, Event Management) and CMDB governance. Configure MID Servers, patterns, probes, and integrations; manage cloud discovery across AWS/Azure/GCP; build automations with Flow Designer and APIs; perform performance and root-cause analysis; liaise with vendors; produce technical strategy, capacity planning, and translate technical solutions for business stakeholders.
Top Skills: APIsAWSAzureCmdbContainersDiscoveryEvent ManagementFlow DesignerGCPItilMid ServerService MappingServicenowServicenow ItomSoa
Reposted 24 Days AgoSaved
In-Office
San Antonio, TX
Senior level
Senior level
Legal Tech • Financial Services
The Development Manager oversees a team of developers, ensuring application solutions align with business needs and maintain high security standards. Responsibilities include strategic planning, stakeholder collaboration, talent management, technical and operational oversight, and promoting continuous improvement and automation in development.
Top Skills: .NetAndroid SdkBootstrapsC#ColdfusionHTML5JavaJavaScriptMicrosoft FabricSharepointSQLSsisSsrsT-SqlTfsVisual StudioWeb Api
15 Days AgoSaved
Remote
San Antonio, TX
Senior level
Senior level
Information Technology • Mobile • Travel
Remote IT Manager responsible for analyzing, upgrading, and administering IT systems (networks, servers, email, backups), evaluating vendors and technologies, managing projects, tracking inventory, training staff, and providing technical support to improve operational efficiency.
Top Skills: Active DirectoryMicrosoft ExchangeZoho
Reposted 15 Days AgoSaved
Remote
San Antonio, TX
100K-130K Annually
Senior level
100K-130K Annually
Senior level
Healthtech • Professional Services
The Senior Clinical Trials IT Business Analyst bridges Clinical Development and IT, optimizing clinical trial technologies and managing system implementations, validations, and stakeholder engagement.
Top Skills: APIsBioclinicalConfident RxElectronic Lab NotebooksEnhanced One PortalHl7Lab Information Management SystemsLab Information SystemsMedidataOracle ClinicalPower BIQlikSite CompanionStarlimsTableauValidation Lifecycle ManagementVeeva
Reposted 15 Days AgoSaved
Remote
San Antonio, TX
110K-135K Annually
Senior level
110K-135K Annually
Senior level
Healthtech • Professional Services
The Senior IT Systems Administrator oversees the administration, security, and optimization of financial systems, ensuring reliability and compliance while leading system enhancements and integrations.
Top Skills: BudgetingCloud SecurityCrystal ReportsErpForecastingMs DynamicsMs Power BiOraclePeoplesoftReporting PlatformsSAPSpssSQLWorkday
16 Days AgoSaved
Remote
San Antonio, TX
95K-136K Annually
Senior level
95K-136K Annually
Senior level
Fintech • Real Estate
Manage full project lifecycle for IT Operations and Services, including enterprise applications, security, network/systems infrastructure, and process improvements. Create plans, governance, change management, vendor onboarding, KPIs, roadmaps, and transition projects to operations while communicating status and driving cross-team collaboration.
Top Skills: AzureExcelMS OfficeSharepointWikiWord
16 Days AgoSaved
Remote
San Antonio, TX
Senior level
Senior level
Big Data • Marketing Tech • Analytics
Lead and manage Level 1-3 Service Desk analysts supporting external clients, oversee daily operations, escalations, SLAs, and reporting. Improve service management, automation, and first-call resolution; partner with Engineering and Incident/Problem/Change Management to resolve production issues. Provide hands-on technical leadership across Splunk, Datadog, MuleSoft, SQL, and ServiceNow while managing client communications and operational metrics.
Top Skills: AICSSDatadogHTMLJavaScriptLinuxMulesoftMySQLPHPSalesforceServicenowShell ScriptingSplunkSQLTableauXML
Reposted 16 Days AgoSaved
Remote
San Antonio, TX
110K-160K Annually
Senior level
110K-160K Annually
Senior level
Information Technology • Software • Cybersecurity • Defense
The IT Operations Director leads Service Desk and Infrastructure teams, overseeing IT operations lifecycle, managing metrics, enforcing security, and enhancing service quality through automation and ITIL processes.
Top Skills: AzureEnterprise NetworkingItilmacOSMicrosoft 365Virtualization PlatformsWindows 11Windows Server
Reposted 16 Days AgoSaved
Remote
San Antonio, TX
110K-140K Annually
Senior level
110K-140K Annually
Senior level
Information Technology • Professional Services • Consulting • Defense
The Enterprise Architect defines technology strategies, aligns investments with company goals, and leads cloud modernization and data analytics initiatives while ensuring compliance and governance.
Top Skills: AIAutomationAWSAzureCloud ModernizationData AnalyticsGCP
Reposted 16 Days AgoSaved
In-Office or Remote
San Antonio, TX
84K-128K Annually
Senior level
84K-128K Annually
Senior level
Energy • Renewable Energy
Manage SAP ERP solutions for finance, design and implement configurations, provide user support, and ensure integration across relevant business areas.
Top Skills: Sap ConfigurationSap Ecc 6.0Sap FicoSap Finance
Reposted 17 Days AgoSaved
Remote
San Antonio, TX
120K-160K Annually
Senior level
120K-160K Annually
Senior level
Edtech
The role involves leading and improving IT operations, focusing on proactive service organization, process design, and team development while managing IT projects and vendor relationships.
Top Skills: It ToolsProcess DesignProject Management
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