Top Remote Python Jobs in Washington, DC

Perform CFD and 1D lumped-parameter fluid analyses for rocket engines, predict component and system performance, build transient and steady models, support testing and anomaly investigations, recommend design improvements, and mentor peers to grow propulsion fluid-analysis capabilities.

Own and advance Yahoo’s enterprise Node.js development environment, including runtimes, packages, container images, internal integrations, and CI/CD workflows. Manage runtime lifecycles, security updates, dependencies, releases, testing, automation, and troubleshooting. Support GitHub Enterprise and GitLab Enterprise while integrating AI programming tools to improve developer productivity. Partner across engineering and security teams, and document platform changes, migrations, and deprecations.

Lead an engineering team delivering automated month-end close pipelines for client accounting teams. Oversee ERP integrations, SQLMesh and DuckDB transformations, journal-entry outputs, controls, reconciliations, exception handling, and approval workflows. Maintain architectural boundaries across Elixir, Python, and platform components while converting bespoke client solutions into reusable capabilities. Manage technical roadmaps, multiple client engagements, engineering standards, and team development while partnering with accounting, delivery, technology, and product stakeholders.

Lead design and delivery of a reliability platform for production systems. Own quarterly goals, guide engineers through ambiguity, collaborate with PM/design/analytics, monitor and operate services (on-call), set quality and code standards, and mentor teammates. Integrate AI/LLM tooling to improve automation, debugging, and service health.

Lead delivery for the Batch Infrastructure team: design, build, and operate reliable, scalable compute platforms for scheduled and on-demand batch workloads. Collaborate with product/design/analytics, define technical plans, ensure availability (monitoring/on-call), set code and design standards, and mentor engineers to improve delivery and quality.

Develop full-stack mission planning and command-and-control software for space communications programs. Build responsive interfaces with modern JavaScript frameworks, backend services and APIs using Python and SQL, and containerized applications. Own features through testing and deployment, write automated tests, collaborate with QA and cross-functional teams, and improve software usability, security, performance, and reliability in highly secure government environments.

Lead delivery and technical execution for an AI-driven pipeline integrity platform spanning data architecture, engineering, data science, application engineering, and QA. Remain hands-on through coding, design reviews, prototyping, debugging, and quality oversight. Manage compliance, security, audit readiness, release planning, hiring, team development, and cross-functional collaboration. Ensure platform outputs are traceable, reproducible, secure, and delivered predictably against phased milestones.

Lead development of high-performance Rust parsers, compilers, automata, indexes, and data structures for structured language-model generation. Optimize decoding-loop performance through profiling and benchmarking, integrate Python bindings and C++/CUDA components into inference engines, collaborate across teams, and maintain production-quality code through testing and CI/CD.

Develop high-performance parsers, compilers, and data structures that constrain LLM decoding according to schemas, grammars, policies, and function definitions. Research parser, compiler, and symbolic methods; write reliable, efficient code; and optimize implementations through rigorous testing and automation. The role requires professional Python expertise, lower-level programming experience, strong formal language knowledge, and clear written communication. It is fully remote with at least three hours of daily overlap with Eastern Time business hours.

Manage and optimize a multi-account AWS environment supporting production healthcare applications and analytics platforms. Responsibilities include AWS infrastructure administration, CI/CD and infrastructure automation, observability, incident response, on-call support, disaster recovery validation, HIPAA/HiTrust compliance, IAM and security controls, and support for containerized Java and Python applications. The role also contributes to Kubernetes and EKS modernization initiatives and partners with developers to resolve complex production issues.

Lead customer implementations of healthcare data platform solutions by configuring the Smile platform, scripting, troubleshooting, designing technical solutions, and providing architectural guidance. Collaborate with customers and internal teams to deliver scalable, secure solutions, support technical analysts, contribute to RFPs, manage concurrent projects, and participate in on-call support.

Develop, deploy, test, and support secure enterprise web applications and healthcare reporting solutions. Responsibilities include full-stack design and development, production issue resolution, SQL and report performance tuning, SSRS and SSIS integration, architecture, testing, deployment, data governance, security, and collaboration with business and technical teams. The role also contributes to scalable solution design, project delivery, mentoring, and understanding payer and provider healthcare analytics.

Design, build, ship, and own high-scale, user-facing product features across frontend, backend, and data systems. Define problems, scope and prioritize work, collaborate with Product, monitor production usage, debug incidents, improve reliability, review code, and mentor engineers. The role requires strong backend expertise alongside React proficiency and ownership from product discovery through long-term maintenance.

Design, build, ship, and own backend product features used by developers and mobile app users at large scale. Scope projects, write reliable and tested code, monitor production systems, participate in architecture and roadmap decisions, respond to incidents, improve scalability and performance, communicate remotely, and mentor engineers. The role requires end-to-end ownership from problem definition through rollout and long-term maintenance.

Build and operate automated compute-capacity systems across regions, including forecasting, provisioning, reservations, fleet reconciliation, drift detection, observability, alerting, and cost optimization. Support demand planning for customer commitments, migrations, and new regions. Contribute to right-sizing, autoscaling, workload consolidation, capacity incident response, and post-incident improvements while coordinating with engineering and finance stakeholders.

Ensure stability and resilience of Runpod's distributed AI platform by defining SLIs/SLOs, leading incident response, building observability and reliability tooling, automating operational workflows, and partnering with engineering teams to reduce toil and improve production readiness.

Build and maintain scalable integration and end-to-end test automation frameworks, optimize CI pipelines and test execution, improve test stability and reporting, support engineering teams with triage and best practices, write technical specs/ADRs, participate in on-call rotation, and collaborate cross-functionally to evolve the company test strategy.

Lead the architecture, scaling, reliability, and security of multi-region AWS infrastructure supporting high-throughput payment systems. Build immutable, self-healing environments with Terraform, Kubernetes, GitOps, CI/CD, and automated resiliency. Develop observability using Prometheus, Grafana, and OpenTelemetry; manage incidents and post-mortems; improve engineering velocity through Golden Paths and platform enablement; and mentor engineering teams on reliable infrastructure practices.

Design, develop, and maintain secure integrations across NetSuite, Coupa, Leapfin, and other enterprise systems. Build iPaaS workflows, custom connectors, webhook and event-driven automations, bulk synchronization processes, monitoring, error handling, and retry mechanisms. Translate finance requirements into technical specifications and data mappings, support implementation projects, document architectures, and maintain audit readiness. Apply AI-powered tooling to automate finance operations while ensuring compliance, security, and reliable handling of sensitive financial data.

Maintain and improve build and release processes across mobile, console, and PC platforms. Develop automation tools, support continuous integration, manage branches and environments, coordinate releases with Production and Live-Ops teams, enable automated testing, and document build pipelines. The role requires Perforce, scripting, build systems, CI, C++, and strong collaboration skills.

Build and productionize customer-facing data and AI solutions on Databricks. Own architecture and design decisions while delivering scalable data pipelines, applications, ML/AI integrations, and user interfaces. Lead technical project delivery, advise enterprise stakeholders, train customers, resolve implementation issues, and contribute reusable engineering assets and product feedback. The role requires strong cloud, distributed computing, software engineering, MLOps, documentation, and customer engagement skills, with travel to customers approximately 20% of the time.

Designs and delivers full-stack software features for electromagnetic warfare test and mission systems. Integrates TCP/IP-connected radios, instruments, servers, and rack components; builds accessible Angular interfaces; supports system evaluation, installation, testing, and sustainment. Develops data pipelines, warehouses, visualizations, threat-signal processing, software distribution tools, and on-premises LLM assistants. Works in Agile and DevSecOps environments while tracking project hours and assisting with effort estimates.

Leads software architecture, full-stack delivery, cross-product integration, and technical quality for ARAT mission systems. Owns classified-enclave deployment, secure GitLab CI/CD pipelines, STIG compliance, RMF and information-assurance coordination, and Windows Army Gold Master compatibility. Establishes shared UI architecture and accessibility standards, designs enterprise test-data platforms and analytics strategies, and governs hybrid cloud, network security, identity, and cross-domain distribution across NIPR, SIPR, and JWICS. Mentors engineers and advises the Government on technical, security, data, and cloud investments.

The Site Reliability Engineer II ensures the reliability, availability, performance, and security of critical cloud systems and services. Responsibilities include developing automation for provisioning and configuration management, maintaining monitoring and alerting, optimizing infrastructure performance, supporting high availability, and enabling continuous integration and delivery. The role collaborates with security teams and drives operational improvements across cloud and network infrastructure.

Lead the architecture and modernization of a complex enterprise SaaS platform while remaining hands-on with critical software design and development. Define technical direction, improve scalability, reliability, security, performance, and maintainability, and guide design and code reviews. Partner across engineering and product teams, resolve complex technical challenges, establish engineering standards, mentor engineers, and translate architectural strategy into practical delivery.