Top Remote Python Jobs in Washington, DC

Designs and develops APIs, system integrations, and AI-agent workflows for enterprise applications. Builds integrations with platforms such as Salesforce and REST APIs, deploys and supports solutions on AWS, and develops AI-powered automation using LLMs, tool calling, and multi-step workflows. The role includes client requirements gathering, troubleshooting, reliability optimization, cross-functional collaboration, and mentoring junior developers.

Leads full-stack and infrastructure engineering teams responsible for simulation platform architecture, cloud infrastructure, container orchestration, databases, APIs, frontend tools, reliability, observability, and cost efficiency. Owns the strategic roadmap for scenario management, run orchestration, taxonomy, and results analytics. Recruits and mentors engineers, partners with simulation teams, manages integration interfaces, and delivers scalable infrastructure for massive parallel batch simulations.

Leads the hands-on development and scaling of Oasis’s healthcare software platform. Responsibilities include architecture, production coding, AWS infrastructure, DevSecOps, AI-native workflows, external system integrations, reliability, observability, compliance, roadmap execution, and recruiting a high-performing engineering team. The role begins primarily as an individual contributor and evolves into player-coach leadership while delivering patient- and provider-facing applications.

Build and maintain scalable infrastructure platforms supporting domestic and international workloads. Develop CI/CD, declarative lifecycle management, Kubernetes clusters, monitoring, and automation systems. Troubleshoot infrastructure issues, respond to alerts, minimize downtime, streamline delivery pipelines and database changes, and help guide SRE team direction. Collaborate with engineers, data scientists, and technology professionals while promoting a high-performance, cross-functional culture.

Build and maintain full-stack software for startup clients, including backend services, frontend experiences, new features, redesigns, bug fixes, and product improvements. Collaborate daily with product managers, designers, and engineers in a distributed, agile environment. Take ownership across the technology stack, write clean maintainable code, contribute to client missions, and support team growth and knowledge sharing.

Build and maintain AWS-based DevOps infrastructure, CI/CD pipelines, containerized microservices, and Infrastructure as Code. Improve observability, resilience, security, compliance, and scalability through monitoring, vulnerability management, system hardening, and performance testing. Collaborate with development teams to resolve outages, contribute to architecture and software development, review code, document systems, mentor engineers, and participate in Agile ceremonies and on-call support.

Leads architecture, design, and hands-on development for scalable backend APIs and interoperability services. Sets engineering standards, drives cross-team technical initiatives, mentors engineers, reviews code and designs, manages technical risks, and partners with engineering leadership on roadmaps. The role focuses on distributed systems, authentication, cloud SaaS, API integrations, and standards such as FHIR, while contributing production code and fostering collaboration.

Leads a remote engineering team building scalable Python and Golang microservices for Canonical’s software distribution marketplaces. Responsibilities include mentoring and developing engineers, managing delivery and expectations, shaping technical strategy and roadmaps, reviewing code, guiding architecture, maintaining engineering quality, and collaborating with product managers, architects, other teams, open-source contributors, and commercial partners.

Leads the Insurance Product Configuration and Enrollment Platform Core, managing engineering managers and 20–30 engineers. Owns technical vision, distributed systems architecture, delivery commitments, operational excellence, testing strategy, partner implementations, and cross-team interfaces. Develops engineering leaders, manages hiring and vendors, and drives adoption of AI-augmented development tools and practices. Ensures scalable, secure, reliable platform services while balancing contractual delivery dates with long-term platform maintainability.

Lead architecture, development, and delivery of Azure SmartNIC and networking software, including RDMA, virtualization, hardware offloads, and high-performance networking. Collaborate across hardware, firmware, silicon, and cloud teams; improve reliability and performance using telemetry; guide platform strategy; troubleshoot production systems; and provide technical leadership through design reviews, mentoring, and incident response.

Design and build unified testing frameworks enabling portability across SIL, HIL, and simulation. Configure and maintain physical HIL benches and hardware interfaces, integrate automated HIL tests into CI pipelines, collaborate with software teams to improve HIL/CI systems, and monitor runtime performance, system health, and reliability metrics across testing platforms.

Performs customer acceptance, user acceptance, smoke, regression, functional, production validation, integration, and automated testing for government systems. Develops test scripts, requirements specifications, traceability matrices, documentation, metrics, training materials, and quality-control processes. Collaborates with engineering teams, vendors, and government stakeholders to troubleshoot issues and improve testing effectiveness. Requires expertise with structured data, relational databases, API testing, scripting, and software testing methodologies. Must be a U.S. citizen and able to obtain Public Trust clearance.

Validates complex enterprise data processing, transformations, migrations, reconciliations, reporting, business rules, APIs, and event-driven workflows. Develops data validation strategies, automated database validation scripts, migration tests, and reconciliation reports. Partners with data architects and engineers while mentoring junior testers. The role requires advanced SQL, automation, ETL validation, relational data modeling, large-scale migration testing, and Python programming.

Design and scale ARM64 compute platform infrastructure, hypervisor integrations, instance management, resource orchestration tools, and compute APIs. Develop and maintain low-level services using Python, Go, or compiled systems languages. Collaborate with hardware and global engineering teams, participate in design reviews, debug distributed Linux systems, and mentor junior engineers.

Designs, simulates, lays out, and characterizes high-speed integrated photodetectors, including PIN, APD, and waveguided structures. Responsibilities include optical and RF modeling, custom mask layout, foundry process optimization, and electro-optic testing of devices operating beyond 200 Gbps per lane. The role requires collaboration with process integration, validation, test, customer, and manufacturing teams to transition photonic components from concept through high-volume production.

Develop and own compute and GPU server platforms from architecture through global deployment. Responsibilities include schematic and layout reviews, design for manufacturability, new product introduction, board and system bring-up, validation, debugging, firmware and BIOS feature management, technology qualification, and vendor coordination. The role requires hands-on server architecture, board-level design, Linux and scripting expertise, platform validation, and five-day-per-week presence in the Cambridge office.

Leads a team of 10 engineers building and maintaining NIBRS and compliance reporting capabilities for public safety records platforms. Oversees technical quality, validation, certification, delivery, incident follow-through, resource allocation, and team development. Partners with product, R&D, agencies, and regulators to implement federal and state reporting requirements, improve engineering operations, and define the roadmap for new states, report types, automation, and platform capabilities. The role is remote within the United States with travel of up to 25%.

Designs, builds, tests, deploys, and optimizes full-stack product features using React and Python. Develops GraphQL integrations, scalable backend services, data visualizations, analytics instrumentation, and production-ready platform capabilities. Contributes to UX workflows, CI/CD, monitoring, code quality, and stakeholder updates while collaborating in agile sprints and evaluating new technologies.

Lead the design, operation, and scaling of AWS cloud infrastructure and Kubernetes production environments for a fintech platform. Build infrastructure-as-code, CI/CD pipelines, observability, and deployment tooling while improving reliability, security, performance, and resilience. Partner on PostgreSQL administration, scaling, backups, and performance tuning. Participate in incident response, root-cause analysis, and operational standards development for sensitive financial workloads.

Develop and maintain Python-based automated test frameworks for software-, hardware-, and model-in-the-loop environments supporting power plant controllers and SCADA systems. Define verification and validation plans, integrate testing into CI/CD pipelines, execute tests across multiple environments, investigate requirements, analyze failures, and perform root cause analysis using engineering tools and telemetry. Collaborate with controls and systems teams to ensure reliable production-ready software.

Define and lead architecture for scalable, cloud-native backend platforms supporting e-commerce, loyalty, identity, payments, and customer engagement. Design event-driven microservices, APIs, integrations, data platforms, and AWS infrastructure while establishing governance, observability, security, resiliency, and CI/CD standards. Provide technical leadership across engineering programs, modernization initiatives, architecture reviews, and enterprise stakeholder collaboration for high-volume QSR and consumer digital ecosystems.

Design, develop, and maintain complex distributed software systems. Write tested, high-quality code; translate product requirements into scalable designs; lead design, code, and sprint activities; collaborate with stakeholders; and mentor engineers. The role also drives technical strategy, resolves delivery impediments, and promotes secure, maintainable, and reusable engineering solutions.

Designs, develops, and maintains complex distributed software systems. Writes high-quality code, leads design and code reviews, translates product requirements into scalable architectures, leads sprint delivery, collaborates with stakeholders, and mentors engineers. The role requires expertise in programming, databases, APIs, messaging, microservices, containerization, DevSecOps, and technical strategy.

Designs and maintains scalable AWS infrastructure, Kubernetes environments, Terraform-based IaC, and CI/CD pipelines. Integrates MLOps and DevSecOps practices, automates deployment and system administration, monitors performance and cost, supports incident response, and collaborates with engineering teams to improve platform architecture and reliability.

Deploys and operates AI-powered customer solutions, owning integrations, authentication, secrets, hosting, monitoring, and releases. Builds reusable tooling and platform components, develops customer-facing AI applications and workflows, leads technical discovery, translates business needs into deployable designs, and partners with Product, R&D, and Customer Success. Requires strong customer communication, software delivery ownership, cloud and DevOps expertise, product thinking, and experience with Python or TypeScript, SQL, REST APIs, and LLM-based systems.