Top Remote Python Jobs in Washington, DC

Design, build, and maintain RESTful, SOAP, and GraphQL APIs; integrate third-party services and databases; implement OAuth2/JWT authentication; optimize performance with caching and load-balancing; document APIs; use Postman/Swagger/OpenAPI/SoapUI; work with cloud platforms, containerization, automated testing, and SQL/NoSQL databases.

Develop and maintain Python applications focusing on iterators/generators/streams, concurrency (multithreading, non-blocking I/O), and high-precision numeric handling. Work with JSON/XML, REST and SOAP APIs, ACID-compliant databases, message brokers/queues, and produce clean, SOLID code. Unit and integration testing experience is beneficial.

Manage stability, performance, and scalability of enterprise block, file, and object storage platforms. Automate provisioning and configuration, perform capacity planning and performance analysis, install and upgrade storage systems and firmware, lead incident response and root cause analysis, support backup and disaster recovery workflows, and collaborate with global infrastructure, database, cloud, and application teams.

Lead and coach a team building internal NOC applications and automation. Oversee full‑stack delivery across private and public cloud, drive workflow automation using APIs, event-driven and AI patterns, ensure production readiness, observability, and collaboration with infrastructure, security, and operations teams to improve reliability and operational efficiency.

Build and ship full‑stack features for transportation management and other client products. Design and implement APIs and UIs, collaborate with product and design, own delivery, write modular testable code, troubleshoot and iterate quickly, and mentor peers.

Build, ship, and maintain production-quality web and mobile products. Contribute across product, design, and engineering, own delivery, write modular testable code, and mentor teammates while iterating quickly to deliver business value.

Lead QA strategy and execution for ARBI and Athena: audit QA, define test architecture, build automated frontend/API/integration/regression suites, validate AI/LLM behaviors and data workflows, integrate tests into CI/CD, perform performance and reliability testing, and own release readiness, metrics, and QA operating rhythms across the product.

Lead the Hosting Platform engineering team owning roadmap, reliability, scalability, and performance for hundreds of thousands of sites. Mentor managers and senior engineers, drive architecture for distributed, multi-tenant systems (edge delivery, caching, databases), define SLOs and observability, manage incident response and customer escalations, balance technical debt, and champion AI-native engineering and automation.

Own quality engineering and test automation for BRINC's LiveOps web platform and backend services. Design and maintain automated API, integration, and end-to-end test frameworks, validate security/IAM controls and ML/vision outputs, build test infrastructure, run performance/load testing for real-time streaming and teleoperation, integrate tests into CI/CD, triage failures, and produce quality metrics and release-readiness reports.

The Software Engineer in Platform Operations designs and manages core infrastructure, ensuring secure, scalable, and reliable platform operations while collaborating with software engineers to improve deployment experiences.

The Senior Data Infrastructure Engineer designs and scales data platforms on AWS, optimizing performance, cost, and security while mentoring junior engineers.

The Database Reliability Engineer manages and maintains cloud-based database infrastructures for SaaS applications, focusing on automation, process improvement, and collaboration with engineering teams.

The QA Engineering Manager will lead a team in building and implementing AI-driven QA processes, focusing on automation, mentoring staff, and ensuring quality standards across product lifecycles.

The Senior Full-Stack Software Engineer will design, build, and maintain secure, scalable web applications using modern technologies, with a focus on AI-assisted development and application security.

As a Senior Software Engineer, you will lead your team in delivering features according to specifications, ensuring scalable technical decisions, and mentoring team members.

The Senior Competitive Benchmarking Engineer will develop benchmark methodologies, analyze performance metrics against competitors, and publish results, requiring strong technical and collaboration skills.

As a Backend Engineer, you will develop and scale PostHog's billing system to support growth, implement flexible billing models, and ensure accurate financial reporting. You'll focus on automating processes and handling complex data modeling.

The role involves building prototypes using Crossmint's APIs, engaging in community interactions, improving developer documentation, and facilitating workshops, with an emphasis on exploring new frameworks and tools in agentic AI and crypto infrastructure.

As a Senior Engineering Manager, you will lead product engineers in enhancing AI-driven SMS marketing solutions for ecommerce brands, focusing on team management, technical mentorship, and operational efficiency.

As a Senior Systems Engineer II for ECG Monitoring Applications, you will design software solutions for arrhythmia detection, manage system architecture, and ensure seamless integration while collaborating with cross-functional teams.

Lead the Payments Team by architecting and maintaining high-performance backend services, addressing complex engineering challenges, and mentoring engineering talent.

Design and deploy AI-driven automation solutions for revenue teams. Enhance productivity tools, integrate systems, and analyze performance metrics.

As a Senior Platform Engineer, you will own and develop the internal developer platform, enhancing GitOps workflows, ensuring reliability, and collaborating with engineering and security teams to improve automation and compliance.

As a Blockchain Developer, you'll design and develop scalable EVM-based solutions for Conduit's platform, improving Node and tooling for onchain compute.

The Solutions Engineer will exceed sales targets, engage with customers, manage feedback, and conduct presentations and demos to promote Netskope's security solutions, requiring extensive technical and customer-facing expertise.