Top Remote Python Jobs in Washington, DC

Lead design, implementation, and maintenance of system architectures across applications, infrastructure, and cloud platforms for federal IT modernization. Provide technical leadership, ensure performance, reliability, and integration, produce documentation, and collaborate with DevOps, security, and stakeholders within Agile teams.

Architect, deploy, and operate highly available multi-cloud infrastructure across AWS and Azure. Manage Kubernetes, Linux systems, databases, caching platforms, CI/CD pipelines, infrastructure as code, observability, security, incident response, and performance optimization. The role also requires automation with Python and Bash, comprehensive documentation, client collaboration, and participation in a 24/7 on-call rotation.

Design and maintain scalable services, APIs, distributed systems, and data pipelines for AI training data infrastructure. Own systems through design, implementation, testing, deployment, and monitoring. Lead architectural decisions, improve reliability and scalability, mentor engineers, and collaborate with AI/ML, product, and data operations teams. Contribute to CI/CD, containerization, DevOps, and cloud deployment practices.

Develop, test, and ship features for data platforms, pipelines, contributor tools, quality assurance systems, and client-facing infrastructure. Collaborate with senior engineers, participate in code reviews, debug issues, and improve automation supporting large-scale AI training data workflows. The role offers hands-on experience with production engineering, data systems, and AI-adjacent technologies in a fully remote environment.

Designs, develops, and maintains automated UI, API, integration, regression, performance, and security tests for enterprise applications including ServiceNow and Salesforce. Builds reusable frameworks, integrates testing into CI/CD pipelines, manages quality gates, validates data with SQL and APIs, diagnoses failures, supports test environments, and collaborates on defect root cause analysis. Provides QA automation standards, metrics, reporting, and technical mentorship.

Build and scale full-stack applications, backend services, APIs, infrastructure, and user experiences supporting millions of users. Design reliable, high-performance systems; partner with Product, Design, and Data; own projects through deployment and optimization; improve observability and developer productivity; and support AI adoption through automation and AI-powered workflows.

Staff Software Engineer leading architecture, hands-on development, and delivery of reliable frontend, backend, API, data, and production systems across multiple teams. The role drives multi-quarter initiatives, AI-enabled engineering practices, system scalability, security, observability, incident response, technical standards, mentorship, and alignment between technical investments and product outcomes.

Designs, builds, and operates secure, scalable cloud infrastructure, deployment pipelines, and operational systems. Owns infrastructure architecture, provisioning, CI/CD, infrastructure-as-code, automation, observability, reliability, cost optimization, and incident response. Leads SRE practices, resolves complex production issues, supports distributed systems and microservices, and collaborates with Product and Engineering teams. Participates in on-call rotations and drives durable solutions that improve platform availability and performance.

Provides staff-level customer-facing technical support for complex multi-cloud networking and security issues. Serves as an escalation point, leading troubleshooting, packet analysis, root cause analysis, deployments, integrations, optimization, and upgrades. Collaborates with sales, solution engineering, and product engineering teams; identifies defects, validates fixes, and improves product quality. Develops technical documentation, runbooks, and troubleshooting guides while advising leadership on recurring customer issues.

Designs, deploys, and troubleshoots enterprise cloud and hybrid network infrastructure across Azure, OpenShift, corporate offices, and security platforms. Administers FortiGate, FortiSASE, Cisco Meraki, Cloudflare, DNS, load balancing, ingress controllers, and Kubernetes networking. Partners with application, security, and cloud teams on deployments and incident response, creates network documentation, manages monitoring and alerting, and performs changes under established procedures.

Lead the architecture, development, operation, and evolution of TetraScience’s multi-tenant Tetra Apps platform. Design containerized application runtimes, routing, identity, security, observability, deployment, and developer tooling. Guide sprint and quarterly planning, write architecture decisions, support production customers, and mentor engineers through technical leadership. Remain hands-on across TypeScript, Node.js, React, Python, AWS, infrastructure-as-code, and CI/CD while safely improving a live platform.

Leads financial systems engineering for a service-contract business. Owns reconciliation systems, invoicing logic, financial data models, revenue recognition controls, and audit reporting. Manages SQL and dbt models, automated validations, exception resolution, merchant configuration audits, and cross-functional escalations across Engineering, Finance, Accounting, and Revenue teams. Leads individual contributors and develops the team as business needs evolve.

Build and maintain Python-based automation, services, test infrastructure, and performance analysis tooling for a distributed database system. Collaborate with internal stakeholders, improve developer tooling and reproducible testing, analyze system performance, and create documentation and runbooks. The role requires strong software fundamentals, systems thinking, Linux and CI experience, and the ability to learn new languages and systems quickly.

Lead the technical direction and delivery of three customer-facing threat intelligence products. Manage a team of senior engineers, own architecture and roadmaps, operate Laravel, Python, and data pipeline services in the cloud, and ensure production reliability through on-call, incident response, and post-incident improvements. Partner with Product Management on quarterly commitments, technical prioritization, team development, and cross-functional architecture decisions.

Build and operate multi-cloud infrastructure for MariaDB Cloud, designing application layers, APIs, cloud-native services, automation, and database-adjacent features. Own production capabilities end to end across AWS, Azure, and GCP using Terraform, Kubernetes, Docker, CI/CD, Python, and backend languages. Develop AI-enabled workflows involving vector databases, semantic search, RAG, and LLM agents while ensuring security, observability, scalability, and reliable deployment.

Maintain and support Java-based healthcare SaaS applications across multiple customer environments. Responsibilities include bug fixes, feature delivery, refactoring, deployments, security remediation, SQL and data migrations, code reviews, configuration improvements, and production support. The role requires a generalist software engineer comfortable with Java, Angular, SQL, REST APIs, enterprise applications, and customer-facing environments.

Designs electrical systems and performs design calculations for data centers, industrial buildings, offices, and other large commercial construction projects. Responsibilities include equipment selection, specifications, submittal and RFI reviews, change orders, record drawings, site observations, inspections, commissioning, and coordination with clients and external disciplines. The role also manages project priorities, budgets, deadlines, and may mentor junior staff.

Develop and maintain automated photonic mask-build workflows, PDK releases, parameterized cells, compact models, and physical verification infrastructure. Build CI/CD pipelines, regression suites, and automated QA for reliable mask releases. Partner with EDA vendors, process engineers, device designers, and architects to automate design workflows, investigate quality escapes, and improve manufacturing readiness.

Manage and maintain complex global network infrastructure, including F5 BIG-IP, Cisco, and HPE Aruba platforms. Investigate and resolve network outages, performance issues, and security incidents; perform upgrades, configuration changes, monitoring, and on-call support. Lead automation initiatives using Python and Ansible, maintain technical documentation, and collaborate with systems, security, and application teams. The role requires 5–7 years of experience and professional vendor certifications are preferred.

Develop algorithms and test methodologies for photonic integrated circuits, run engineering and prototype tests, analyze test data using JMP and Excel, create high-volume production test processes, and troubleshoot hardware and software integration. The role requires programming, test automation, statistical analysis, test instrument experience, and familiarity with optoelectronic devices. This is a full-time, four-month onsite cooperative role in Sunnyvale, California.

Build and optimize growth features, experimentation frameworks, personalization strategies, onboarding flows, and engagement loops for Pika’s AI creative platform. Analyze user data, run A/B tests, improve performance and reliability, and collaborate with product, marketing, design, and data teams to drive acquisition, activation, engagement, retention, referrals, and virality.

Build and ship full-stack features, including REST APIs, single-page applications, data models, cloud-based containerized services, and relational database solutions. Translate product requests into deliverable work, contribute to architectural decisions, review pull requests, and protect patient data by maintaining strict PHI-handling practices. Work in a trunk-based development environment with short-lived branches, frequent releases, and continuous collaboration.

Develops, tests, deploys, and supports attended and unattended UiPath RPA automations. Works with stakeholders to analyze processes, gather requirements, identify automation opportunities, and translate needs into technical solutions. Builds database and API integrations using SQL and programming languages, applies web technologies for browser automation, and maintains documentation. Troubleshoots automations, supports Agile and Waterfall development, participates in testing and project planning, and provides operational status updates.

Implements, optimizes, and supports healthcare IT solutions for clients. Analyzes healthcare data, translates business requirements into technical solutions, leads deployments and integrations, provides training and troubleshooting, manages client escalations, and monitors system performance. Requires strong knowledge of healthcare workflows, HL7, FHIR, HIPAA, data analysis, and client-facing technical support.

Designs and maintains DevSecOps infrastructure for AWS-hosted microservices and APIs. Builds CI/CD pipelines, containerized deployments, and Infrastructure as Code using Terraform, CDK, or CloudFormation. Develops monitoring, logging, and performance tools; supports security reviews, vulnerability management, and resilient systems. Requires strong AWS, EKS/Kubernetes, networking, scripting, programming, troubleshooting, Agile collaboration, and SRE skills.