Top Senior Machine Learning Jobs in Houston, TX

Leads Hightouch’s machine learning organization, including product development, technical roadmapping, recruiting, reliability, and people management. The role focuses on personalization, product recommendations, probabilistic identity resolution, LLM-powered content generation, and scalable machine learning infrastructure for model training and inference.

Develop applied AI research prototypes and systems for agentic marketing applications, focusing on generative image and video, brand asset creation, data workflows, and autonomous evaluation. The role combines probabilistic and quantitative reasoning, backend system architecture, product intuition, experimentation, and customer-focused product development. Responsibilities include building proofs of concept, improving AI-generated media realism and brand alignment, and architecting agentic systems.

Design and launch 0-to-1 AI-powered marketing tools for Hightouch’s Agents product suite. Responsibilities include rapid prototyping, customer research, synthesizing usage data and feedback, shaping product strategy, and collaborating with designers, engineers, and product managers. The role requires strong visual, UI, and interaction design skills, comfort with ambiguity, curiosity about AI, and rapid iteration in a remote-first environment.

Owns multistate U.S. property and casualty insurance product filings from drafting through approval, including AI model documentation, SERFF submissions, objection responses, and regulatory inquiries. The role supports carrier clients, monitors state requirements, develops scalable filing processes, and coordinates with data science, actuarial, product, counsel, regulators, and industry stakeholders. Requires strong technical writing, insurance regulatory expertise, independent judgment, and the ability to translate complex predictive modeling methods into regulator-acceptable documentation.

Manage complex customer issues, triage support activity, and coordinate escalations across Client Engagement, Product, Engineering, and project teams. Analyze tickets and feedback to identify trends, risks, process gaps, and product opportunities. Improve support operations through documentation, dashboards, workflows, routing logic, playbooks, and feedback loops. Serve as a customer advocate while supporting strategic initiatives and strengthening handoffs, prioritization, and operational decision-making.

Lead data engineering and machine learning initiatives by designing, architecting, developing, and supporting GCP data pipelines. Create information architecture documentation, estimate and plan technical work, collaborate with project teams and business analysts, and translate requirements into technical designs. Develop Python-based ELT pipelines, optimize BigQuery SQL, support CI/CD, and provide technical leadership to projects and teams.

Leads the data science platform and machine learning strategy, building data marts, predictive models, MLOps infrastructure, and analytics capabilities. Analyzes healthcare claims, clinical, workflow, and operational data to risk-stratify patients, assess clinical program impact, support dashboards, and improve patient and provider engagement. Collaborates with clinical, operations, finance, product, executive, and technology teams while serving as a trusted analytics expert for a business workstream.

Design and operate large-scale, AI-native cloud infrastructure (especially Kubernetes/AKS). Improve service quality, automate incident prevention/remediation, accelerate engineering productivity, and integrate AI tools into development workflows.

Design, build, and operate high-throughput, low-latency ad-serving infrastructure processing millions of requests per second. Optimize GPU-powered TensorRT inference, feature stores, model serving, benchmarking, experimentation tooling, and system reliability. Partner with machine learning engineers to productionize models and own systems through design, deployment, observability, capacity planning, incident response, and optimization.

Leads complex enterprise customer engagements as a technical authority for Databricks data and AI solutions. Drives architecture, platform adoption, consumption strategy, competitive positioning, and executive relationships. Designs large-scale data, streaming, migration, governance, and AI/ML solutions; orchestrates cross-functional teams; mentors other solutions architects; and contributes to technical thought leadership. Requires advanced coding, enterprise data architecture expertise, Databricks proficiency, strategic account leadership, and executive communication.

Lead product-focused data science and machine learning initiatives, including exploratory analysis, production model development, evaluation frameworks, generative AI, graph-based machine learning, recommendation systems, and personalization. Collaborate with engineering, product, and business teams to deliver high-impact solutions, influence strategy, and communicate insights to technical and non-technical stakeholders. The hybrid role requires four days per week in the Greater Boston area.

Senior legal executive leading institutional bank partnerships, complex commercial and program agreements, consumer lending regulatory strategy, data protection, intellectual property, and AI underwriting compliance. The role advises executive and cross-functional teams, manages bank due diligence and risk requirements, and translates legal and regulatory considerations into scalable business strategies.

Leads the creation and global scaling of an AI Data Operations practice. Responsibilities include defining service strategy, developing AI data and evaluation solutions, originating and closing client engagements, establishing quality and governance frameworks, building strategic partnerships, providing thought leadership, and enabling scalable managed-service delivery. The role combines AI expertise, consulting, sales, solution design, commercial leadership, and global operations.

Leads the Growth Algorithms data science team, setting strategy for acquisition, activation, retention, and reactivation. Oversees experimentation, causal inference, predictive modeling, personalization, CRM, paid media, and lifecycle initiatives. Partners across Product, Marketing, Engineering, Finance, Design, and Analytics to prioritize high-impact work, improve decision-making, guide production-quality systems, and develop a high-performing team of data scientists.

Provides statistical strategy and biostatistical oversight for pharmaceutical clinical trials, including protocols, SAPs, clinical study reports, regulatory documentation, analyses, randomization, and vendor deliverables. Develops innovative statistical methodologies and tools, supports clinical development programs, reviews data management documentation, and contributes to cross-functional standards and infrastructure initiatives.

Manage data analysis for transaction monitoring, risk identification, and compliance. Analyze high-volume transaction data using SQL, Python, Splunk, and visualization tools; conduct root-cause investigations; design risk data architectures; identify process and reporting improvements; advise business and product teams; and translate technical findings into executive recommendations. The role also involves stakeholder liaison, regulatory alignment, data integrity, and managing concurrent analytical projects.

Design, build, test, deploy, and operate frontend applications, backend services, data pipelines, and AI systems. Lead technical initiatives, own production features end to end, scale reliable systems, run A/B tests, and partner with product and operations teams to automate healthcare workflows using deterministic logic, machine learning, and LLMs.

Own and deliver production machine learning workstreams for utility bill extraction, forecasting, and audit/anomaly detection. Build and evaluate models, establish technical approaches for ambiguous problems, write production-grade Python, and partner with engineering on integration and monitoring. The role also involves applying LLMs and agentic workflows, automating team processes, prioritizing investments, and communicating model behavior and recommendations to technical and nontechnical stakeholders.

Develop and optimize GPU-accelerated numerical linear algebra libraries for AI and high-performance computing. Design kernel generation, JIT compilation, matrix operations, and operator fusions; lead projects involving multiple engineers and teams; provide technical mentorship; collaborate with product management and customers on requirements and roadmaps; and improve performance and maintainability through architectural enhancements.

Provides senior functional and technical leadership for NetSuite and connected financial systems. Partners with Finance, Accounting, and technology teams to design processes, configure NetSuite, manage integrations, protect close-cycle continuity, support production incidents, implement controls, coordinate releases, and deliver testing and documentation. The role also leads automation initiatives, vendor engagement, solution lifecycle delivery, and mentorship while supporting accounting, compliance, reporting, and multi-entity financial operations.

Staff Software Engineer responsible for setting technical direction, architecting scalable distributed systems, shipping high-impact features, and building AI-powered tools for a virtual healthcare platform. The role includes mentoring engineers, partnering with product and clinical leadership, translating user needs into technical solutions, and guiding frontend and backend application development in a fast-paced startup environment.

Lead mainframe modernization and migration architecture for large global clients. Conduct discovery workshops, assess legacy environments, develop transformation and re-platforming solutions, present technical business cases, and advise executives. Partner with sales, consulting, operations, product management, and clients to create solutions, influence technology roadmaps, drive stability and innovation, and support complex opportunities. The role requires deep mainframe expertise across legacy languages, databases, operating systems, infrastructure, and modernization technologies.

Leads the full lifecycle of clinical NGS diagnostic algorithms for oncology and liquid biopsy applications. Responsibilities include algorithm design, analytical validation, design control, regulatory readiness, variant calling, QC metric development, probabilistic modeling, machine learning, and validation pipeline automation. The role serves as technical authority for algorithm changes, supports regulatory submissions, and develops solutions for low-input, fragmented, and ultra-low-frequency genomic variants.

Leads enterprise evaluation, governance, and implementation planning for emerging mental health therapeutics, including digital therapeutics, AI-enabled tools, neuromodulation, pharmacotherapies, and technology-enabled care models. Develops clinical protocols, workflows, provider training, safety criteria, outcome measurement, and adoption support. Partners with clinical, technology, research, quality, operations, and growth teams; evaluates vendors and evidence; monitors regulatory developments; and advances responsible innovation across the organization.

Leads end-to-end customer onboarding and implementation programs, translating customer goals into project plans, milestones, dependencies, risks, and success metrics. Coordinates Sales, Product, Engineering, Support, Customer Success, trainers, and subject-matter experts without performing hands-on technical implementation or training. Establishes scalable operational frameworks, manages cross-functional accountability, oversees technical readiness, tracks adoption, facilitates stakeholder communications, and ensures customers are prepared for go-live.