Top Python Jobs in Des Moines, IA

Own end-to-end product features for a SaaS platform serving HR, therapists, and employees. Build, scale, and evolve frontend and backend components, lead architecture and standards, collaborate with design and product, and incorporate customer feedback and QA. Work in an early-stage startup environment with product-focused ownership.

Build and maintain async Python backend services and FastAPI APIs supporting high-volume attention measurement products. Collaborate with data engineering, data science, product, and customer success teams to integrate data pipelines, models, and production features. Responsibilities include testing, code reviews, performance tuning, production troubleshooting, monitoring, reliability improvements, and working with AWS infrastructure, databases, and Airflow-orchestrated workflows.

Build and maintain Python backend services and serverless architectures for a restaurant operations platform. Ship end-to-end features, design robust systems, and help define product roadmap. Implement CI/CD and productionization, collaborate with product and GTM teams, and contribute to team culture and technical execution.

Modernize legacy SAS data-processing systems by translating logic into scalable, high-performance Python solutions. Build and optimize large-scale data pipelines using formats including SAS, Parquet, JSON, and SQL. Integrate PostgreSQL, implement parallel processing, automated testing, data validation, and quality assurance, and maintain well-documented code. Collaborate with IT specialists and stakeholders to validate requirements, troubleshoot issues, and deliver cloud-native modernization solutions.

Lead the design, development, and operation of production-grade automation, agent frameworks, and CI/CD pipelines supporting documentation, localization, and language operations. Integrate platforms through REST APIs and MCPs, apply LLM capabilities responsibly, improve reliability and scalability, establish reusable standards, and mentor engineers. The role is fully remote in the US, with preferred Eastern or Central time zone availability.

Build and maintain Django-based web applications, design RESTful APIs, implement frontend features (HTML/CSS/JS), optimize performance and security, collaborate with cross-functional teams throughout the development lifecycle.

Design, develop, and maintain scalable Python applications; collaborate with cross-functional teams to deliver features; ensure performance and quality; identify and fix bugs; maintain code quality and automation; lead and mentor team members using agile practices.

The Senior Python Engineer will develop and support MongoDB Python drivers, enhance library quality, and collaborate on product features.

Build and maintain scalable backend applications, serverless functions, microservices, data workflows, ETL pipelines, and cloud-native architectures using Python and AWS. Manage databases, APIs, batch jobs, and real-time integrations while optimizing performance, scalability, security, compliance, and cost. Collaborate with product, engineering, analytics, and data teams; contribute to architecture, CI/CD, infrastructure automation, development standards, and technical mentorship. Healthcare claims data experience is required.

Work as a Python development intern building applications and APIs, processing and analyzing data, working with databases and data pipelines, contributing to system architecture, writing clean documented code, and collaborating with the team. Strong emphasis on backend development, SQL, ORMs, and REST API design with potential conversion to full-time.

Build and maintain scalable Python-based AI applications under senior guidance. Assist with requirements, feature implementation, data modeling using Pydantic, code reviews, troubleshooting, testing, and CI/CD. The role requires collaboration, communication, and willingness to learn modern Python tools, frameworks, and libraries. Candidates should understand object-oriented programming, REST APIs, large language models, and AI coding tools. The position is fully remote within the United States.

Evaluate AI coding-agent interactions for usefulness, correctness, engineering judgment, reasoning quality, and developer trust. Provide clear, opinionated feedback, distinguish response-quality levels, and help define standards for excellent interactions with tools such as OpenAI Codex, Claude Code, and Cursor. This contract role requires staff- or principal-level software engineering experience and familiarity with modern AI-assisted development workflows.

Design, develop, test, and maintain scalable Python applications, backend services, REST APIs, microservices, and integrations. Work with databases, asynchronous processing, cloud platforms, containers, CI/CD, security, observability, and distributed systems. Troubleshoot production issues, optimize performance, create automated tests, participate in code reviews and architecture decisions, and collaborate with product, DevOps, QA, and engineering teams.

Develop open source SDKs, enterprise APIs, UIs, and backend systems supporting large-scale computer vision datasets. Build scalable, maintainable, performant, and well-tested software for unstructured data and AI workflows. Contribute to enterprise deployments across customer clouds and on-premises environments, while improving tooling, automation, engineering practices, and open source community initiatives in a remote-first team.

Develop and maintain Python software applications, backend services, APIs, integrations, and database solutions. Responsibilities include troubleshooting, testing, deployment, code review, performance monitoring, documentation, and collaboration with a distributed remote team. The role requires independent work, strong communication, and reliable delivery of maintainable, scalable software.

Design, develop, and maintain scalable Python applications and cloud-native solutions. Architect microservices, containerized deployments (Docker/Kubernetes), optimize cloud infrastructure, build CI/CD pipelines, integrate messaging systems, ensure security and high code quality, and mentor junior developers. Generative AI/ML experience is a plus.

Design and evaluate performance engineering tasks for AI training/evaluation. Optimize runtime, compilers, memory, CPU/GPU and concurrency. Produce documented solutions, evaluate AI-generated code, and build evaluation frameworks and scoring rubrics while collaborating with researchers and SMEs.

The Senior Full Stack Developer will design, develop, test, and debug software solutions, collaborating with teams and optimizing applications. Responsibilities include user interaction design, back-end functionality, and ensuring software scalability and security.

The Backend Software Engineer will develop and maintain backend systems for data processing related to coffee farming, utilizing Python and PostgreSQL. Responsibilities include feature development, problem-solving, and adapting systems to regulatory changes while ensuring system resilience.

Develop, test, and maintain a complex distributed processing application using Python and Java. Collaborate with product owners, data coaches, analysts, DBAs, and Agile teams to meet backend/frontend requirements. Work with distributed workloads (Spark/Hadoop), SQL/Snowflake, AWS, shell scripting, and job scheduling/process automation. Support delivery under Agile/SAFe practices and ensure alignment with program standards.

Lead development of Python-based web applications using Django and FastAPI, architect scalable solutions, and establish technical standards while mentoring developers and optimizing infrastructure.

As a Python and Kubernetes Software Engineer, you will develop data analytics solutions using open source tools, collaborating with a distributed team.

Develop, test, and release improvements to Ubuntu on public clouds, ensuring quality and stability, while collaborating with a global team.

The Python Engineer will write maintainable Python software, lead technical initiatives, collaborate globally, and contribute to community engagement at Canonical.

The role involves designing and delivering open source software operations code in Python, ensuring system reliability, and collaborating with teams across the Linux stack.