Top Machine Learning Jobs in San Luis Obispo, CA

2 Days AgoSaved
Remote
San Luis Obispo, CA
200K-200K Annually
Senior level
200K-200K Annually
Senior level
Information Technology • Professional Services • Database
Designs and operates production multi-agent AI systems, LLM workflows, scoring and optimization algorithms, and closed-loop autonomous processes. Responsibilities include AI model evaluation, production monitoring, governance, third-party AI integration, federated data retrieval, and identifying patentable inventions. The role requires deep machine learning expertise, algorithm development, and deployment experience across complex operational environments.
Top Skills: AutogenCrewaiDigital TwinsEmbeddingsFederated LearningIotJaxKnowledge GraphsLangchainLanggraphLarge Language ModelsMlflowMulti-Agent AiPythonPyTorchRayReinforcement LearningRetrieval-Augmented GenerationSemantic SearchVector DatabasesWeights & Biases
Reposted 2 Days AgoSaved
Remote
San Luis Obispo, CA
Senior level
Senior level
Payments • Software
As a Machine Learning Engineer, you will design, build, and deploy ML models for underwriting at Stripe Capital, ensuring performance while collaborating with multiple teams.
Top Skills: PyTorchSparkTensorFlowXgboost
25 Days AgoSaved
Remote
San Luis Obispo, CA
140K-150K Annually
Senior level
140K-150K Annually
Senior level
Social Impact
Lead end-to-end product strategy and delivery for a core marketplace area, collaborating with engineering, UX, and design. Conduct qualitative and quantitative research, run agile sprints, measure results with analytics, and pioneer AI/ML product features and workflows to improve user experience and platform impact.
Top Skills: AIAshbyFullstoryGoogle AnalyticsMachine LearningPosthogSQL
25 Days AgoSaved
Remote
San Luis Obispo, CA
191K-258K Annually
Senior level
191K-258K Annually
Senior level
Software
Lead go-to-market for Mapboxs AI products: define positioning, messaging, and launch strategy; drive customer research, sales enablement, content, and cross-functional alignment to accelerate adoption of AI-powered location capabilities.
Top Skills: AIAPIsDeveloper PlatformsLocation IntelligenceMachine LearningMapboxSaaSSdks
25 Days AgoSaved
In-Office or Remote
San Luis Obispo, CA
197K-295K Annually
Senior level
197K-295K Annually
Senior level
Legal Tech • Software
Lead document-vision research and production systems for multimodal legal evidence understanding. Define evaluation standards, frame hard problems, design and ship models, run efficacy studies and monitoring, mentor senior scientists, and advise leadership on scientific direction.
Top Skills: Computer VisionDeep LearningInformation RetrievalMachine LearningNatural Language Processing (Nlp)OcrPythonVision-Language Models
25 Days AgoSaved
In-Office or Remote
San Luis Obispo, CA
208K-312K Annually
Senior level
208K-312K Annually
Senior level
Legal Tech • Software
Lead and grow an applied science team building reliable, production-ready generative AI systems for legal use. Own end-to-end AI system readiness, set technical direction, perform evaluations and error analysis, partner cross-functionally to move work to scale, hire and coach staff, and represent the team externally.
Top Skills: Ai SystemsBusiness IntelligenceData AnalysisData GovernanceData VisualizationDatabase ManagementGenerative AiInformation RetrievalMachine LearningProduction Monitoring
25 Days AgoSaved
Remote
San Luis Obispo, CA
137K-182K Annually
Senior level
137K-182K Annually
Senior level
Biotech
Lead development and application of analytics, statistical models, and dashboards to support R&D Quality oversight. Integrate clinical, safety, lab, and operational data to identify risks, support audit/inspection readiness, enable RBQM, and provide actionable quality insights and recommendations to cross-functional partners.
Top Skills: Anomaly DetectionAPIsCloud PlatformsData WarehousesEtl/EltGenerative AiGitMachine LearningMS OfficeNatural-Language ProcessingPower BIPredictive ModelingPythonRSQL
25 Days AgoSaved
Remote
San Luis Obispo, CA
250K-275K Annually
Expert/Leader
250K-275K Annually
Expert/Leader
Insurance • Software
Lead and grow a 9-10 engineer cross-functional team to own AI product areas (Quote Agent, Submission Triage, Product Studio). Define architecture for agentic/LLM systems, ensure engineering quality, partner with Product/Design/GT M stakeholders, and drive delivery of scalable, production AI features while fostering ownership and continuous growth.
Top Skills: Agentic SystemsAIB2B Enterprise SaasData AnalyticsLlmsMachine Learning
25 Days AgoSaved
Remote
San Luis Obispo, CA
Senior level
Senior level
Biotech
Lead strategic vision and execution of next-generation bioinformatics technologies. Identify and evaluate emerging computational methods, translate research into production-grade pipelines and prototypes, support product roadmaps and technology transfer, and partner cross-functionally to commercialize genomic and AI-driven healthcare solutions.
Top Skills: AIAWSAzureBioinformatics PipelinesC++Genomic DatabasesGCPJavaMachine LearningMulti-OmicsNgsPythonR
25 Days AgoSaved
Remote
San Luis Obispo, CA
150K-245K Annually
Senior level
150K-245K Annually
Senior level
Artificial Intelligence • Consumer Web • Information Technology • Real Estate • Software • PropTech
Lead combined Analytics Engineering and Data Engineering teams owning the end-to-end data roadmap from ingestion to trusted metrics. Manage hiring and performance, set architecture and platform investments, enforce testing/monitoring/documentation standards, review technical decisions, and partner with product and business stakeholders to translate needs into prioritized deliverables.
Top Skills: Bi Semantic LayerCi/CdData WarehousingGenerative AiLookerMachine LearningPipeline OrchestrationSQLTableau
25 Days AgoSaved
Remote
San Luis Obispo, CA
216K-235K Annually
Expert/Leader
216K-235K Annually
Expert/Leader
Fitness • Healthtech • Payments • Software
Lead pricing and monetization strategy across global markets. Design pricing models and packaging, optimize discounting and payments economics, apply AI/ML analytics to drive revenue and margin, partner cross-functionally with Product, Sales, Finance, and Revenue Operations, govern pricing changes, and enable sales with pricing tools, policies, and training to improve ARR, retention, and profitability.
Top Skills: Ai-Driven Pricing ToolsCrm/CpqEmbedded PaymentsFintechMachine LearningPayments PlatformsPredictive AnalyticsSalesforce
Reposted 25 Days AgoSaved
Remote
San Luis Obispo, CA
75K-85K Annually
Mid level
75K-85K Annually
Mid level
Information Technology • Transportation
Analyze historical demand, occupancy, transactions and competitor pricing to optimize daily, monthly, and event pricing. Build dashboards, deliver revenue insights to leadership, and collaborate with Operations and Marketing to implement pricing and promotional strategies while maintaining data integrity.
Top Skills: ExcelMachine LearningParking Revenue Control SystemsPower BIPythonRSQLTableauVBA
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25 Days AgoSaved
Remote
San Luis Obispo, CA
191K-260K Annually
Senior level
191K-260K Annually
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Marketing Tech • Software • Biotech • Design
Provide senior legal and regulatory counsel for digital health and medical device products (SaMD), guiding product lifecycle, FDA and global filings, AI-enabled features, labeling, compliance, post-market obligations, and cross-functional governance. Lead strategy, manage external counsel, and translate regulatory developments into business guidance.
Top Skills: AIConnected HealthEu MdrFdaIso StandardsMachine LearningSamdWearable Technology
Reposted 2 Days AgoSaved
Remote or Hybrid
San Luis Obispo, CA
160K-240K Annually
Senior level
160K-240K Annually
Senior level
Artificial Intelligence
Design, train, and deploy scalable ML models (generative, classification, regression). Define feature roadmaps, collaborate with engineering to implement code and APIs, adapt ML methods for distributed/GPU environments, and create evaluation/annotation programs for fine-tuning and performance measurement.
Top Skills: Apache BeamSparkApi DevelopmentDistributed SystemsGpuPythonPyTorchTensorFlow
Reposted 25 Days AgoSaved
Remote
San Luis Obispo, CA
Senior level
Senior level
Cloud • Software • Analytics
Lead product management for AI tools in software/SaaS, manage product lifecycle, drive strategic roadmap, and ensure product adoption through iterative shipping and user feedback.
Top Skills: AIAPIsCloud InfrastructureMachine LearningSaaSSoftware
Reposted 25 Days AgoSaved
In-Office or Remote
San Luis Obispo, CA
225K-260K Annually
Senior level
225K-260K Annually
Senior level
Robotics
Develop and scale machine learning training systems for robotics data, optimize training pipelines, and collaborate with ML researchers to enhance autonomy models.
Top Skills: Distributed Training FrameworksMachine LearningNeural NetworksPython
Reposted 25 Days AgoSaved
Remote
San Luis Obispo, CA
175K-200K Annually
Senior level
175K-200K Annually
Senior level
Software
Lead Buildertrend's end-to-end payments risk and operations: merchant onboarding, underwriting, transaction monitoring, disputes, chargebacks, and portfolio management. Build AI-assisted fraud prevention, scale automation, embed risk controls with Product and Engineering, develop analytics and governance, and grow a high-performing team to balance risk and business growth.
Top Skills: AchAIAPIsCheck DisbursementsFraud Detection PlatformsMachine LearningPayment ProcessingTransaction Monitoring Systems
Reposted 25 Days AgoSaved
Remote
San Luis Obispo, CA
200K-250K Annually
Expert/Leader
200K-250K Annually
Expert/Leader
Information Technology • Consulting
Senior leader responsible for building and scaling pre-award solution engineering capabilities to support federal sales. Oversees technical demonstrations, RFP/RFI responses, demo readiness, reusable accelerators, and cross-functional alignment with Growth and executive leadership to drive differentiated, secure solutions using modern data and AI platforms.
Top Skills: AIAi InfrastructureCybersecurityData PlatformsGenerative AiMachine LearningMl PlatformsModern Data Architectures
Reposted 3 Days AgoSaved
Remote
San Luis Obispo, CA
230K-270K Annually
Senior level
230K-270K Annually
Senior level
Software
Lead design, development, and production deployment of ML and algorithmic solutions. Own end-to-end ML systems, support distributed production reliability, communicate tradeoffs, and apply generative AI, LLM fine-tuning, RAG, and agentic techniques to product problems.
Top Skills: Agentic AiHuggingfaceKubernetesLlmsPyTorchRag PipelinesScikit-LearnSpacy
Reposted 26 Days AgoSaved
In-Office or Remote
San Luis Obispo, CA
Senior level
Senior level
Insurance
Senior individual contributor responsible for leading pet/P&C insurance pricing model development (GLMs and ML), owning end-to-end projects, performing EDA and root-cause analysis, communicating results to stakeholders, and mentoring junior team members.
Top Skills: GlmMachine LearningPythonRegression ModelingSQLStatistical Inference
Reposted 3 Days AgoSaved
In-Office or Remote
San Luis Obispo, CA
1M-1M Annually
Entry level
1M-1M Annually
Entry level
Healthtech • Travel • Analytics • Consulting
Develop, implement, and deploy scalable machine learning models for healthcare solutions. Collaborate cross-functionally to integrate models, analyze data to improve performance, ensure data quality, and stay current with ML advancements to support patient care and operational efficiency.
Top Skills: JavaPythonPyTorchRScikit-LearnTensorFlow
Reposted 3 Days AgoSaved
Remote
San Luis Obispo, CA
Senior level
Senior level
Automotive • Healthtech • Financial Services
Lead end-to-end ML system development: data exploration, model research, training, deployment, evaluation, and MLOps. Collaborate cross-functionally to prioritize claims, improve matching, measure business impact, and own a technical workstream.
Top Skills: AiopsAWSAzureGCPHugging FaceMlopsPythonPyTorchScikit-LearnSparkTensorFlowTransformers
3 Days AgoSaved
Remote
San Luis Obispo, CA
Senior level
Senior level
Cloud • Information Technology • Professional Services • Software
Design and scale production AI/ML systems, including autonomous agents, LLM integrations, retrieval pipelines, and virtual assistants with voice capabilities. Build and optimize models, training and deployment pipelines, APIs, and cloud-native services. Apply agent frameworks, vector databases, RAG, fine-tuning, observability, and MLOps practices. Collaborate on architecture, evaluate emerging reasoning and tool-use approaches, and mentor engineering peers.
Top Skills: APIsAWSAzureChromaCi/CdCrewaiDockerEmbeddingsFaissGCPKubeflowKubernetesLangchainLlamaindexMicroservicesMlflowMlopsPineconePythonPyTorchRagSagemakerTensorFlowTransformersVector DatabasesVertex AiWeaviate
Reposted 3 Days AgoSaved
Remote
San Luis Obispo, CA
248K-310K Annually
Senior level
248K-310K Annually
Senior level
Real Estate • Travel • PropTech
Responsible for fine-tuning state-of-the-art LLMs, optimizing models for deployment, and driving AI architectural decisions. Collaborate with cross-functional teams to develop impactful AI products.
Top Skills: PythonPyTorch
Reposted 3 Days AgoSaved
Remote
San Luis Obispo, CA
143K-197K Annually
Senior level
143K-197K Annually
Senior level
Healthtech • HR Tech
Build and maintain scalable ML and generative AI platforms and backend infrastructure; deploy and manage production applications; create services exposing ML/AI products; implement RAG solutions and vector databases; integrate LLM orchestration and foundation model APIs; collaborate cross-functionally and mentor teammates.
Top Skills: AnthropicAws BedrockDockerFastapiKubernetesLangchainLlamaindexLow-Latency DatabasesOpenaiPythonRagRelational DatabasesServer-Sent EventsVector DatabasesWebsockets
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