Top Machine Learning Jobs in San Luis Obispo, CA

Design, scale, and optimize ClickUp's search infrastructure using OpenSearch/Elasticsearch. Improve relevance, speed, and real-time indexing, build vector search capabilities, create evaluation frameworks, and collaborate with AI/backend/product teams to integrate and troubleshoot search at scale.

Lead payments analytics by building scalable reporting, causal inference and ML models, designing experiments, partnering with product/engineering/finance to optimize payment processing, reconciliation, and settlement, and translating results into executive recommendations to drive global payments improvements.

Manage full-cycle recruiting for technical and consulting roles with emphasis on AI talent. Partner with leaders to build sourcing strategies, pipelines, and candidate evaluation for LLMs, prompt engineering, ML, and AI governance roles. Maintain ATS data, report metrics, document recruiting best practices, and deliver strong candidate and hiring manager experiences.

Design and build backend systems and APIs for AI-driven products, ensuring scalability, reliability, and integration of ML models while collaborating with engineering and product teams.

Lead supply chain analytics engagements: manage client teams, design data-driven solutions for demand forecasting, inventory and network optimization, drive key initiatives to closure, and provide thought leadership in supply chain analytics.

The Senior Backend Data Engineer will extend data ingestion and processing pipelines, build APIs and backend services, and provide technical leadership.

Lead Tekmetric's API product strategy and roadmap for the SaaS platform. Own API lifecycle (contracts, versioning, documentation), drive developer experience and adoption, identify integration opportunities, lead generative AI initiatives, perform user research and analytics-driven prioritization, collaborate across design/engineering/sales, train internal teams, and measure business impact.

The Data & Analytics team at Surescripts transforms healthcare data into actionable insights, collaborating with various stakeholders to support critical decisions across the healthcare ecosystem.

The Principal Data Scientist will design, develop, and deploy machine learning models, innovating methodologies and collaborating across teams to enhance financial decision-making and risk management.

Lead sales and deployment of custom AI/ML solutions, driving pipeline and revenue for allocated accounts. Collaborate with Field Sales, Product, Sales Engineering and AI teams to discover requirements, architect agentic AI solutions, write SOWs, negotiate commercial terms, and manage complex sales cycles to ensure customer adoption and measurable business outcomes.

One-year, full-time fellowship supporting design, delivery, and evaluation of interventions for smallholder farmers. Duties include research and analysis, pilot design, field implementation, M&E, and cross-team collaboration with heavy mentorship and rotating in-country placements.

Support revenue cycle by performing coding reviews, claim scrubbing, and payer audit management to prevent denials and recoupments. Use Power BI, advanced Excel, and a machine-learning tool to detect trends, validate exceptions, and drive upstream/downstream interventions. Liaise with stakeholders, track payer audit performance, and deliver operational improvements and monthly scorecards to leadership. Remote role focused on mental/behavioral health revenue integrity.

Lead planning, execution, and optimization of cross-functional hardware and software projects for robot development, manufacturing, testing, upgrades, and deployments. Coordinate mechanical, electrical, embedded, systems, manufacturing, and operations teams, define scope and timelines, mitigate risks, implement process improvements, run sprints, and maintain project documentation and stakeholder communication.

Lead Woolpert's partner marketing for the Google relationship: develop and execute joint go-to-market plans, run integrated campaigns, enable sales, create partner collateral, measure KPIs, and coach one specialist to drive co-selling and pipeline growth for Digital Innovations.

Lead enterprise account sales in Southern California by hunting new logos, growing existing accounts, and closing deals. Own full sales cycle, build pipeline, collaborate with BDRs, solutions architects, and marketing, articulate ROI of AI solutions, and use AI tools to enhance prospecting and forecasting to meet quota.

Lead statistical activities for Phase I-IV clinical trials from protocol design through reporting. Provide statistical oversight, collaborate cross-functionally, supervise programmers/CROs, apply SAS/R and ML/DL methods for analyses and automation, and support regulatory, safety, and publication deliverables.

Lead development of Vanta's business analytics function: build scalable product data assets, define measurement frameworks, use AI-assisted analytics, partner with cross-functional teams, and deliver executive-level recommendations to drive product and business decisions.

Lead and grow a global engineering team building endpoint visibility, prevention, and on-device ML across Windows, macOS, and Linux. Own roadmap and delivery, direct model development and telemetry, drive cross-platform protection parity, coordinate with product and partner teams, and represent the team externally through research and conferences.

Build and own end-to-end product features across React/TypeScript frontend, Ruby on Rails backend, relational databases, and GCP/AWS infrastructure. Partner with product, design, clinical, and operations teams to translate complex healthcare workflows into simple experiences. Improve reliability and performance, mentor engineers, raise engineering standards, and integrate AI-powered features into production.

Senior individual contributor building and maintaining underwriting and credit decisioning ML systems for Cash App Borrow and Afterpay. Responsibilities include feature engineering, model training, calibration, experimentation, deployment, monitoring, and portfolio-level analysis. Collaborate with cross-functional teams to align models with business and regulatory goals and develop AI-native engineering workflows and governance for reliable, auditable model development.

Lead statistical design and analysis for Phase I-IV clinical studies, develop protocols and SAPs, perform efficacy and exploratory analyses, run simulations, apply advanced methods (mixed models, longitudinal), oversee datasets (ADaM/CDISC), use R and SAS for analyses, and provide strategic statistical guidance to cross-functional teams supporting regulatory submissions.

Lead strategy, build and scale a global partnerships ecosystem (ERP, fintech, banks, ISVs, VARs, SIs) to drive partner-sourced pipeline, revenue, and platform expansion. Own partner negotiations, commercial models, cross-functional integration, and team development while leveraging AI/data insights and ensuring compliance.

Lead and grow a team of 5-7 enterprise sales reps in the Bay Area, recruit and develop sales leaders, build business plans, drive new-logo acquisition and account expansion, manage the sales cycle from lead generation to close, develop GTM strategy, and report to the VP of Sales. Role supports ambitious quarterly and annual goals and may require occasional work outside standard hours.

Drive supply chain efficiency through data analytics, KPI development, process redesign, ERP/WMS/automation selection and implementation, Lean Six Sigma continuous improvement, AI-driven forecasting, cross-functional project leadership, audits, and change management with suppliers and 3PLs.

Lead the vision and execution of data product roadmap; translate business needs into epics and acceptance criteria; partner with data engineering and analytics; run agile ceremonies and manage backlog; champion data-as-a-product; scope and pilot AI/ML capabilities; present roadmaps and business cases to leadership.