Top Senior Linux Jobs in San Diego, CA

Leads integration of benchtop NGS assays into robust, automated, production-ready workflows for an FDA-cleared diagnostics platform. Responsibilities include labware qualification, DOE-based robustness testing, failure-mode analysis, acceptance criteria, verification and validation, sequencing integration, vendor diligence, and collaboration with assay science, automation engineering, Regulatory, and Quality. The role requires hands-on experience with NGS platforms, library preparation, secondary analysis, Hamilton liquid handlers, VENUS software, and regulated laboratory processes.

Design, develop, test, and deploy ETF application systems across backend and frontend. Build APIs, automated tests, CI/CD pipelines, and support production releases. Collaborate with multi-location teams and clients, champion AI-assisted development and code quality.

Develops and maintains mainframe applications and IBM Content Manager OnDemand environments. Responsibilities include platform administration, monitoring, upgrades, patching, configuration management, database and application integrations, production L2/L3 support, on-call participation, audit and compliance support, retention enforcement, and disaster recovery testing. The role also contributes to mainframe DevOps initiatives using GitLab, CI/CD, automated testing, and supports financial-services business continuity requirements.

Lead the architecture and implementation of scalable full-stack systems, ensuring high performance and security while mentoring engineers and defining best practices.

Design and evaluate mechanical systems for an advanced nuclear reactor project. Responsibilities include reactor vessel and high-temperature component design, electromechanical device documentation, systems engineering, requirements and configuration management, code compliance, testing, fabrication oversight, inspection, assembly, installation, and reactor experimentation support.

Leads design, development, testing, integration, and troubleshooting of advanced fiber-optic, laser, and electro-optic systems for aerospace and defense applications. Uses Zemax to design and optimize optical systems, develops precision alignment and manufacturing processes, creates technical documentation and test protocols, supports laser safety compliance, and serves as an optical subject matter expert across engineering, manufacturing, quality, and program teams.

Serve as the primary technical resource for customers using servo valve solutions. Troubleshoot and optimize hydraulic, mechanical, electrical, and electromechanical systems; recommend products; conduct site assessments and valve tuning; translate customer needs into technical requirements; provide training; and collaborate with engineering, manufacturing, supply chain, and product teams.

Own reliability, scalability, and operational excellence for Zoom’s globally distributed real-time communications platform. Lead SLO/SLI development, incident response, postmortems, chaos engineering, observability, capacity planning, infrastructure architecture, deployment safety, and cost optimization. Partner with engineering, security, product, data, and global teams while guiding SRE practices, technical initiatives, architecture reviews, and operational readiness across real-time media services.

Lead architecture and development of Beacon’s backend Datastore platform, including PostgreSQL data models, Kafka event pipelines, GraphQL APIs, integrations, and clinical-data access controls. Design scalable systems, tune queries, operate production databases, guide schema evolution, debug cross-system issues, write RFCs, mentor engineers, and improve tooling, documentation, testing, and operational robustness. The role offers focus either on broad Datastore systems or deep PostgreSQL and data modeling.

Leads manufacturing maintenance reliability, preventive maintenance, downtime reduction, root-cause analysis, and continuous improvement initiatives. Develops maintenance standards, SOPs, asset and MRO inventory processes, and capital expenditure plans. Partners with maintenance, bottling, processing, controls, and equipment manufacturers to improve uptime, safety, quality, cost, and OEE. Tracks KPIs, supports audits, manages equipment upgrades, and coordinates projects to completion.

Designs, develops, supports, and optimizes ERP and EDI integrations across Oracle ERP, SaaS, and boundary systems. Diagnoses interface, performance, and data integrity issues; leads integration onboarding for acquisitions and distributors; develops scalable integration architectures; supports Infor tools; and ensures secure development, testing, documentation, and change management. Collaborates with stakeholders to deliver efficient, high-impact technology solutions.

Leads controls and electrical maintenance activities for a distillery, including automation planning, PLC/HMI/VFD standardization, troubleshooting, preventive maintenance, project management, safety compliance, and cost-saving initiatives. Supervises and develops 3–5 electrical and instrumentation technicians, maintains controls documentation, supports production uptime, and coordinates regulatory, environmental, quality, and food safety requirements.

Develop and own solidification physics for high-temperature investment castings: predict and control mushy-zone feeding, shrinkage, porosity, and grain structure; design processes and custom foundry hardware; develop thermal/solidification simulations; perform root-cause analysis; transition processes to qualified production and collaborate with cross-functional teams and customers.

Lead design, architecture, and deployment of custom manufacturing equipment. Translate process requirements into scalable mechanical systems, drive build vs. buy decisions, prototype and commission hardware, and establish practices for equipment development. Report to CEO, shape technical roadmap, and grow a mechanical engineering and equipment organization.

Lead development and production readiness of high-temperature superalloy castings for aerospace applications. Own process development from melt to accepted hardware, eliminate defects, tighten process windows, develop SPC/DOE-led controls, work with simulation and equipment teams, and transition processes to stable production while interfacing with customers and stakeholders.

Designs, administers, and optimizes IBM z/OS storage infrastructure, including DASD and virtual tape platforms. Manages replication, disaster recovery, GDPS recovery environments, backup, cyber resiliency, capacity planning, performance optimization, and data lifecycle policies. Develops automation and monitoring solutions, troubleshoots complex storage issues, supports resiliency testing, and collaborates with infrastructure, application, operations, engineering, and vendor teams on modernization and continuous improvement.

Designs and operates enterprise AI platforms using AWS Bedrock, AgentCore, MCP servers, and cloud-native technologies. Responsibilities include observability, distributed tracing, logging, cost governance, monitoring, incident management, IAM and ABAC security, Terraform infrastructure, CI/CD automation, and platform standardization. The role collaborates with architecture, engineering, security, and business stakeholders to deliver reliable, secure, scalable, and cost-efficient AI infrastructure.

The Quality Engineer develops and maintains inspection methods, quality procedures, test plans, acceptance criteria, and quality documentation. Responsibilities include investigating nonconformances, complaints, and CAPAs; analyzing quality metrics and defect trends; managing supplier quality; supporting audits; ensuring ISO 9001 compliance; designing verification tools and fixtures; and leading continuous improvement across manufacturing, testing, production, and field service operations.

Provides escalated technical support for Hitachi microscopy and focused ion beam systems. Responsibilities include fleet performance testing, installations, maintenance, troubleshooting, customer training, documentation, performance reporting, trend analysis, fieldwork coordination, and technical presentations. The role guides other support engineers, collaborates with internal and external stakeholders, supports continuous improvement, and owns projects using project management methodology. Travel to customer sites in Oregon is required approximately 50% of the time.