Top Senior Machine Learning Jobs in San Diego, CA

18 Days AgoSaved
Easy Apply
In-Office or Remote
San Diego, CA
Easy Apply
200K-230K Annually
Senior level
200K-230K Annually
Senior level
Artificial Intelligence • Hardware • Healthtech • Software
Lead the Data + ML Platform team to design, build, and operate scalable data and MLOps infrastructure. Drive platform strategy, enable ML experimentation-to-production workflows (model registry, feature stores, drift monitoring, experiment tracking), modernize streaming and batch pipelines, and scale the team while partnering cross-functionally to deliver measurable outcomes.
Top Skills: Batch Data PipelinesDrift MonitoringExperiment TrackingFeature StoreLlmMlopsModel RegistryMultimodal Sensor DataOffline Feature StoreOnline Feature StoreShadow DeploymentsStreaming Data PipelinesTraining Data ManagementVlm
Reposted 12 Days AgoSaved
In-Office or Remote
San Diego, CA
169K-305K Annually
Senior level
169K-305K Annually
Senior level
Cloud • Security • Software • Cybersecurity
The Senior Product Architect will design security products, collaborating with product management and engineering teams, focusing on architecture and functionality for high-level product features.
Top Skills: AIBig Data AnalyticsMachine LearningWeb Technologies
Reposted 12 Days AgoSaved
Remote
San Diego, CA
99K-180K Annually
Senior level
99K-180K Annually
Senior level
Pharmaceutical
Lead data quality and data management for oncology studies, overseeing DM teams, vendor/CRO management, and compliance with CDISC/ICH-GCP. Develop risk management, integrate and surveil multi-source data, advise stakeholders on data collection and standards, produce metrics and dashboards, manage project resourcing and finances, review contracts, and deliver training to ensure high-quality, regulatory-compliant clinical and real-world data.
Top Skills: AICdiscHadoopIch-GcpMachine LearningMeddraPythonRSASSdtmShinySparkSQLTableauVersion ControlWhodrug
23 Days AgoSaved
In-Office
San Diego, CA
140K-190K Annually
Senior level
140K-190K Annually
Senior level
Artificial Intelligence • Internet of Things • Machine Learning • Robotics
Founding-team product engineer owning full-stack UX and backend for a vision-based Physical AI product. Build real-time dashboards, compliance analytics, operator scoring/coaching workflows, and agentic AI features. Design APIs and data models, iterate rapidly with customers, and ship data-dense interfaces integrating video, alerts, and conversational/LLM surfaces.
Top Skills: Artificial IntelligenceAWSClaude CodeCodexComputer VisionCursorEdge ComputingGoJavaScriptLlmsMachine LearningPythonTypescript
Reposted 13 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Information Technology • Software
The Vice President of AI will define and lead the AI strategy at Tempo, integrating AI capabilities into products, building teams, and ensuring ethical use of AI while driving business outcomes and customer value.
Top Skills: Ai SystemsData PlatformsData ScienceGenaiMachine Learning
Reposted 13 Days AgoSaved
In-Office or Remote
San Diego, CA
58K-175K Annually
Senior level
58K-175K Annually
Senior level
Legal Tech
Support development of pricing arrangements, financial models, budgets and AFAs for a law firm. Produce pricing analyses, competitive market research, and performance metrics. Collaborate with attorneys, IT, and data teams to implement pricing tools (Elite 3E, Iridium), leverage AI/analytics for forecasting, and train stakeholders on pricing technology.
Top Skills: AIData WarehouseElite 3EIridiumMachine LearningExcelOutlookPower BIPowerPointPredictive Analytics PlatformsPythonRSQLTableauWord
4 Hours AgoSaved
In-Office or Remote
San Diego, CA
125K-237K Annually
Senior level
125K-237K Annually
Senior level
Healthtech • Pharmaceutical
Lead design and build of ML systems: architect training, deployment, inference, and monitoring at scale. Collaborate cross-functionally, enforce data quality/governance, integrate ML into production, mentor engineers, and evaluate new ML/AI technologies including LLMs and MLOps practices.
Top Skills: AirflowAWSCi/CdDockerGitHuggingfaceKubernetesLlmsMicroservicesMllibPandasPysparkPythonPyTorchScikit-LearnSQLTensorflow/Keras
14 Days AgoSaved
Remote
San Diego, CA
256K-350K Annually
Senior level
256K-350K Annually
Senior level
Information Technology • Consulting
Lead technical customer engagements and guide cross-functional teams to design, build, and deploy enterprise-scale AI solutions. Provide architecture and program leadership for LLMs, RAG, ML, and cloud-native systems; establish engineering standards, CI/CD, observability, and AI governance; mentor engineers and support business development.
Top Skills: Agentic AiAirflowAPIsCi/CdCloud (AwsDevOpsDockerGenerative AiGoogle Cloud Platform)KafkaKubernetesLarge Language Models (Llms)LlmopsLoggingMachine LearningMicroservicesAzureMlopsMonitoringObservabilityPrompt EngineeringRetrieval-Augmented Generation (Rag)SparkStreaming Technologies
14 Days AgoSaved
Remote
San Diego, CA
178K-300K Annually
Senior level
178K-300K Annually
Senior level
Information Technology • Consulting
Lead customer-facing design, development, and deployment of AI-enabled software solutions. Translate stakeholder needs into scalable architectures, build production-quality code and APIs, implement CI/CD and observability, and mentor engineering teams. Drive solution discovery, technical leadership across projects, and adoption of modern AI/ML and DevOps practices to deliver mission-critical outcomes.
Top Skills: Agentic AiAutomated TestingAWSC#Ci/CdDevOpsDistributed SystemsGenerative AiGoogle Cloud PlatformJavaJavaScriptLarge Language ModelsMachine LearningMicroservicesAzurePythonRest ApisRetrieval-Augmented Generation (Rag)TypescriptVersion Control
14 Days AgoSaved
In-Office or Remote
San Diego, CA
230K-365K Annually
Senior level
230K-365K Annually
Senior level
Cloud • Information Technology • Internet of Things • Professional Services • Software
Drive enterprise software revenue by prospecting, closing, and expanding accounts. Build long-term pipeline, meet license/support/service targets, orchestrate complex multi-stakeholder deals, leverage channels, position machine learning and predictive analytics, and collaborate cross-functionally to deliver customer value.
Top Skills: AnalyticsApplication DevelopmentCloudDevOpsIt SystemsMachine LearningPredictive AnalyticsSaaSSecuritySplunk
Reposted 14 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Healthtech • Professional Services • Biotech • Pharmaceutical
The Senior Data Scientist will manage data collection, design study protocols, train juniors, lead report development, and support innovative analytics tools.
Top Skills: Data AnalysisMachine LearningProject Management FrameworksStatistical Analysis
Reposted 14 Days AgoSaved
In-Office or Remote
San Diego, CA
Senior level
Senior level
Travel
The Senior Product Manager will lead the integration of airline and third-party partners, optimize supply metrics, and leverage AI for automation. Responsibilities include managing APIs, collaborating with engineering, and improving the booking experience.
Top Skills: AIAPIsMachine Learning
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Reposted 14 Days AgoSaved
Remote
San Diego, CA
257K-402K Annually
Senior level
257K-402K Annually
Senior level
Robotics
The Director of AI will lead AI and machine learning initiatives, develop AI architecture for humanoid robots, oversee production-ready AI systems, and manage team growth and budget.
Top Skills: AIComputer VisionIsaac SimMachine LearningMlopsMujocoNatural Language ProcessingPhysics-Based SimulationReinforcement LearningRobotics
Reposted 14 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Machine Learning • Software
The Senior Machine Learning Engineer will design, prototype, build AI systems, evaluate ML models, and improve Vectara's AI Agents with a focus on reliability and performance.
Top Skills: Deep LearningMachine LearningNatural Language ProcessingPandasPythonPyTorchRetrieval-Augmented GenerationTransformers
Reposted 14 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Fintech • Software • Financial Services
As a Senior Machine Learning Engineer, you'll build and deploy ML models for risk and fraud detection, leading technical efforts and collaborating cross-functionally.
Top Skills: Machine LearningPythonSQL
Reposted 14 Days AgoSaved
Remote
San Diego, CA
181K-475K Annually
Senior level
181K-475K Annually
Senior level
Fintech • Healthtech • Analytics
The VP of Sales will drive enterprise adoption of AI-powered healthcare software, engage with stakeholders, and shape go-to-market strategies for new AI products.
Top Skills: AIHealthcare SoftwareMachine Learning
Reposted 14 Days AgoSaved
Remote
San Diego, CA
225K-255K Annually
Senior level
225K-255K Annually
Senior level
Security
As a Machine Learning Engineer, you'll design, build, and maintain models to detect security threats, ensuring model efficiency and aligning initiatives with business goals.
Top Skills: AWSDockerGCPGenerative AiKubernetesLlmsMachine LearningPandasPythonScikit
Reposted 14 Days AgoSaved
Remote
San Diego, CA
210K-300K Annually
Senior level
210K-300K Annually
Senior level
eCommerce • Retail • Software
Lead the vision and strategy for the Commerce Intelligence Platform, transforming data assets into scalable, revenue-generating products, fostering cross-functional collaboration and driving market growth.
Top Skills: AIData PlatformsMachine LearningProduct Management
Reposted 14 Days AgoSaved
Remote
San Diego, CA
173K-375K Annually
Senior level
173K-375K Annually
Senior level
AdTech • Digital Media • Information Technology • Other
Lead Yahoo's Data Activation product area: define vision and strategy, partner with Data Science and Engineering, drive cross-vertical data activation initiatives, deliver measurable business impact, and mentor/manage product teams to execute on audience, personalization, and targeting use cases.
Top Skills: AgileAIGoogle Cloud PlatformMachine LearningScrumSQL
Reposted 14 Days AgoSaved
Remote or Hybrid
San Diego, CA
240K-330K Annually
Senior level
240K-330K Annually
Senior level
Artificial Intelligence • Automotive • Machine Learning • Transportation
This role leads the ML Acceleration team, focusing on enhancing ML model training efficiency and team management, while driving technical strategy and collaboration.
Top Skills: AWSAzureC++GCPJaxMachine LearningMl FrameworksPythonPyTorch
Reposted 14 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
AdTech
Lead the Performance ML team at MNTN, driving strategy and deployment of predictive models for ad technology, while managing, mentoring, and scaling engineering teams.
Top Skills: Data ScienceGoogle Cloud PlatformMachine Learning
25 Days AgoSaved
In-Office
San Diego, CA
139K-257K Annually
Senior level
139K-257K Annually
Senior level
Biotech • Pharmaceutical
Lead Lab-in-the-Loop data science for hit finding by developing in silico strategies (cheminformatics, generative AI, agentic workflows), building scalable data pipelines, and partnering with experimental and computational teams to accelerate early drug discovery.
Top Skills: Agentic/Agent-Based FrameworksCheminformaticsCloud EnvironmentsDatabasesDeep LearningEnamine RealGenerative AiGraph AlgorithmsHigh-Performance ComputingLinuxMachine LearningMake-On-Demand ChemistryNlpPandasPythonRSQL
15 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Security
Lead delivery of advanced analytics and investigative support for federal programs. Manage multiple concurrent projects, schedules, costs, risks, personnel, vendors, and stakeholder communications to ensure quality, timely contract-aligned deliverables.
Top Skills: AgileArtificial IntelligenceCloud-Based PlatformsData GovernanceEnterprise Data ManagementFraud AnalyticsGraph AnalyticsInvestigative AnalysisMachine Learning
Reposted 15 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Payments • Software
The Data Science Manager will lead and mentor a team of data scientists, drive data-driven decision-making across Stripe, and collaborate with various stakeholders. Responsibilities include managing projects, recruiting, and contributing to broader data science initiatives.
Top Skills: Computer ScienceEconomicsEngineeringMachine LearningOperations ResearchStatistics
16 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Cloud • Software
Design, build, and operate production AI platform capabilities and agentic workflows. Collaborate on architecture, write production-quality backend code, mentor developers, troubleshoot production issues, and drive adoption of reusable AI frameworks, MLOps practices, and cloud-native intelligent services across a multi-tenant SaaS dental platform.
Top Skills: Amazon BedrockAnthropicAPIsClaude CodeCloud-Native ArchitecturesCursorGithub CopilotLanggraphLlmsMachine LearningMcp ServersOpenaiPythonRetrieval-Augmented Generation (Rag)Semantic SearchVector Databases
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