Top Senior Machine Learning Jobs in San Diego, CA

Leads AI/ML engineering teams across platform and delivery pods, managing employees and contractors while enforcing code, agent, review, and production-readiness standards. Partners on reusable templates, pipelines, and evaluation processes, ensures adoption across teams, manages contractor performance and conversion, and removes delivery blockers. The role requires hands-on credibility reviewing agent architectures, prompts, and evaluation suites, with experience operating as a player-coach in fast-moving organizations.

Develop and optimize machine learning and statistical models for fraud detection and anti-money laundering. Analyze large datasets to identify fraudulent patterns, build scalable data pipelines and features, evaluate model performance, and collaborate with engineering, product, and operations teams. Communicate insights to technical and non-technical stakeholders while maintaining data privacy and security compliance. The role offers significant ownership in building Oscilar’s early machine learning stack within a remote-first startup.

Own LanceDB’s product direction by shaping the roadmap with technical leadership, researching users and competitors, gathering continuous user insight, and driving cross-functional prioritization. The role partners closely with engineering as a technically respected peer, defines product changes for AI and data-platform users, uses metrics and experiments to guide decisions, and operates with high ownership in an ambiguous environment.

Advise enterprise clients on AI and data strategies, transformation roadmaps, operating models, governance, privacy, technology rationalization, and business cases. Lead discovery workshops, executive engagements, and art-of-the-possible sessions; prioritize use cases and connect technical recommendations to business outcomes. Build the advisory practice, develop offerings, manage multidisciplinary teams, mentor staff, strengthen client and partner relationships, and support successful distributed project delivery.

Develop new enterprise and upper mid-market business, manage client accounts, and serve as a trusted consulting advisor. Prospect and qualify leads, collaborate with technical teams to create proposals and close SOW contracts, identify business improvement opportunities, build channel partnerships, maintain CRM records, and support localized marketing activities. The role is remote within specified target markets, includes up to 10% travel, and has no direct reports.

Designs and maintains high-volume HL7 and FHIR ingestion pipelines, secure Epic and hospital integrations, data validation systems, and compliant healthcare data exchanges. Builds enterprise SaaS microservices using ReactJS, Python, and AWS services; optimizes distributed and hybrid-cloud environments; leads testing, code reviews, production troubleshooting, architecture documentation, and customer communications. Preferred experience includes Epic App Orchard, healthcare integration engines, clinical workflows, GenAI/ML, DevOps, data pipelines, and NoSQL.

Tune AML and fraud detection models using customers’ live transaction data. Investigate missed cases, alert quality, pattern drift, and false positives; validate changes through backtesting and sample review; document regulatory rationale; and present model performance and business value to compliance, risk, and data science stakeholders. Partner with customer teams on account strategy and relay customer-specific or systemic findings to product and model functions.

Drive net-new enterprise customer acquisition from lead generation through contract closure. Build C-level relationships, develop account strategies, manage CRM pipelines and forecasts, negotiate complex contracts, and close large AI, machine learning, and data talent engagements. Partner with marketing, customer success, and talent teams to deliver customer outcomes and expand Factored AI’s enterprise footprint.

Consult as a fractional data scientist for hedge funds, private equity firms, and family offices. Lead data science initiatives: build infrastructure, develop and deploy models, create portfolio dashboards, monitor post-deployment performance, and partner with investment teams to turn data into actionable investment insights. Advise on vendor selection, data quality, technology stacks, KPIs, and governance.

Coordinates data platform incident response, triage, escalation, root cause analysis, problem management, post-incident reviews, and operational improvements. Maintains runbooks, documentation, metrics, dashboards, and stakeholder communications. Implements and monitors security controls, supports security incident response, vulnerability remediation, compliance audits, regulatory reporting, disaster recovery exercises, and cross-functional coordination across data, cloud, infrastructure, DevSecOps, application, and governance teams.

Develop and deploy predictive and causal models for personalization, retention, monetization, and product strategy. Design experimentation and measurement frameworks, analyze user and marketing behavior, quantify business impact, and translate complex findings into strategic decisions. Collaborate with Product, Engineering, Marketing, and Data Product teams to build scalable data solutions. Mentor peers, promote rigorous model validation and governance, and apply Python, SQL, Snowflake, dbt, Airflow, Spark, and AWS to production-ready data science initiatives.

Lead the design and implementation of large-scale AI and machine learning systems for Yahoo Search across multiple teams. Define data strategies, evaluation frameworks, and scalable production-serving approaches. Drive technical alignment among engineering, product, design, and research teams; guide adoption of large language models, vision models, generative AI, and agentic AI; and oversee data analysis informing strategic product decisions.

Drive enterprise sales growth across North American banking, credit card, and financial services accounts. Develop strategic account and business development plans, build customer and partner relationships, close complex multi-million-dollar technology deals, and engage C-level stakeholders. Represent the company at industry events, collaborate with commercial and leadership teams, manage pipeline forecasting and reporting, and apply MEDDPICC methodology. The role focuses on cybersecurity, fraud prevention, authentication, and SaaS or cloud solutions, with 50% domestic and international travel.

Triage AI opportunities, shape technical solutions, write precise SOWs and internal handovers, identify reuse vs. new engineering, and coordinate sales and engineering to deliver scoped AI engagements (5–10 concurrently, 30–45 day cycles). Ensure delivery-ready documentation and flawless handoffs to implementation teams.

Own the technical side of deal progression for airline deployments: qualify opportunities, run demos and POCs, author integration and deployment architectures (PSS, APIs, data feeds, DNS, identity, networking), respond to RFPs/security questionnaires, scope SOWs and NFRs, and build reusable demo/reference assets to drive adoption and expansion while liaising between sales, engineering, and customers.

Lead the design, development, deployment, and governance of advanced analytics, machine learning, and AI solutions using large healthcare datasets. Responsibilities include data preparation, statistical and predictive modeling, model monitoring, explainability, visualization, stakeholder communication, and translating findings into clinical and operational improvements. The role also mentors data professionals, advises leaders, manages initiative priorities and risks, and promotes responsible AI and Agile practices.

You will tackle AI challenges, develop scalable software and collaborate with teams to enhance healthcare navigation using AI solutions.

Lead and transform the Fraud Intelligence Team into a high-impact function by improving operating models, QA, tooling, and metrics; build entry-level talent programs; connect labeling to measurable fraud prevention outcomes; deliver actionable insights to Product, R&D, Analytics, and GTM; and leverage AI and automation to increase productivity and business impact.

Partner with functional leaders to translate business strategy into people strategy. Own org design, performance management, compensation, talent development, engagement, and retention. Provide coaching on career pathing, change management, and sensitive employee issues. Use people data to generate insights and recommendations, build compliant HR policies, manage global employee relations, and collaborate with People Team COEs to deliver cohesive people programs at scale.

Serve as second-in-command for Coinbase Derivatives' Market Regulation Department, leading day-to-day regulatory compliance, managing exams and audits, advising on CFTC Core Principles, reviewing surveillance escalations and enforcement actions, and coordinating cross-functional regulatory workstreams to ensure the DCM meets obligations and resolves findings timely.

Manages city-level autonomous vehicle and robotaxi fleet operations, including team leadership, vehicle deployment, maintenance tracking, service coverage, safety, KPIs, and site performance. Partners with product, engineering, regulatory bodies, and local stakeholders to support technology updates, service enhancements, rider experience, and market launches. Leads continuous improvement, change management, and operational strategy while ensuring reliable and safe service delivery.

Apply and optimize advanced ML models (including multimodal transformers) to support drug discovery. Collaborate with chemists and biologists, evaluate models, integrate ML insights into design-make-test-analyze cycles, communicate results internally and externally, and guide ML model evolution with domain-driven feedback.

Lead Software & AI Engineer responsible for designing, developing, and deploying software solutions integrating AI/ML. Requires extensive experience in cloud-native development and DevSecOps.

The Staff Machine Learning Engineer will design and build scalable ML systems, mentor engineers, and drive AI strategy at SailPoint, focusing on AI-powered identity security solutions.

Provide legal guidance on Rubrik's AI use and products, ensuring compliance with laws and contracts, drafting and negotiating AI terms, coordinating generative AI review processes, educating employees, and improving AI review controls and workflows across cross-functional teams.