Top Senior Machine Learning Jobs in San Diego, CA

Lead and manage the underwriting and credit risk model validation team, perform hands-on independent validations of complex ML models, assess data integrity and performance, identify and remediate model weaknesses, partner on MRM framework improvements, and coordinate with audit, compliance, and controls to meet regulatory standards.

Leads enterprise AI strategy and operations by building AI product portfolios, agentic workflows, copilots, intelligent applications, and human-AI experiences. Partners with executives, engineering, data science, security, and business teams to prioritize opportunities, establish roadmaps, redesign workflows, drive adoption, govern AI initiatives, and measure business value. Builds and leads AI product management teams while overseeing organizational change and cross-functional portfolio governance.

Drive new enterprise revenue and customer expansion by selling AI-powered SaaS solutions. Manage complex 6–12 month sales cycles, build executive relationships, develop value propositions, maintain pipeline accuracy, lead virtual account teams, and close high-value deals. Translate technical AI capabilities into measurable business outcomes, guide customer adoption, collaborate with marketing, product, and customer success teams, and exceed quarterly pipeline and revenue targets.

Lead product vision, strategy, discovery, and Agile delivery for insurance platforms. Partner with engineering, data science, design, QA, and insurance domain teams to prioritize opportunities, manage backlogs, evaluate build-versus-buy decisions, guide technical design, coordinate delivery, and measure outcomes. The role requires strong knowledge of insurance policy lifecycles, integrations, data modeling, pricing, underwriting, and AI-enabled workflows.

Leads product strategy, roadmap prioritization, AI and automation initiatives, client engagement, and cross-functional delivery for SPINS Intelligence and Portal. The role combines hands-on product management with PM team leadership, including writing user stories, defining acceptance criteria, triaging issues, reviewing sprint output, managing product economics, and developing business cases. Requires strong CPG, SaaS analytics, data product, AI/ML, and technical platform expertise.

Own Sophos EDR strategy, roadmap, technical product development, AI-powered experiences, and go-to-market execution. Translate customer needs, threat research, telemetry, competitive intelligence, and business goals into product priorities. Partner with engineering, security operations, threat research, marketing, sales, and customer success to deliver endpoint detection, investigation, threat hunting, response, reporting, and XDR/MDR upgrade capabilities while driving adoption, revenue, and customer outcomes.

Claims Counsel advises on auto insurance coverage, multi-state tort law, civil procedure, and litigation matters. Responsibilities include drafting coverage opinions, researching insurance laws, supporting claims policies and training, collaborating with legal and claims teams, conducting adjuster training, and drafting form letters and releases.

Designs production-ready AI architectures for enterprise customer-experience use cases. Leads presales discovery, demonstrations, prototypes, pilots, integrations, and solution validation involving LLMs, RAG, agentic AI, workflows, enterprise data, and cloud ecosystems. Establishes evaluation, observability, governance, security, scalability, latency, and cost strategies while influencing CIO and CTO stakeholders. Partners with sales, Professional Services, Product Management, and Engineering, and develops reusable enablement assets to scale field AI expertise.

Lead the design and optimization of the VA VHA AI Education Hub, including its AI learning assistant, sandbox, integrations, analytics, and healthcare data models. Apply machine learning, synthetic data, privacy-preserving methods, and responsible AI practices in a secure federal healthcare environment. Collaborate with VA stakeholders and technical teams, document solutions, ensure governance and compliance, and present platform metrics and findings to leadership.

Serve as the technical sales and customer-facing expert for an AI platform. Responsibilities include conducting product demonstrations, supporting proofs of concept, advising on architecture and development, planning professional services projects, tuning retrieval and agentic pipelines, responding to RFPs, supporting customer adoption, and communicating product feedback internally. The role requires strong AI, cloud, on-premise, application development, storytelling, and enterprise customer engagement experience.

Architect and prototype scalable solutions for Twilio’s emerging technologies experimentation team. Lead AI, machine learning, and LLM-driven initiatives; guide technical direction; mentor engineers across the US and India; align prototypes with business goals; and ensure enterprise architecture, scalability, extensibility, and production readiness. The role requires extensive architecture or principal engineering experience, cloud expertise across AWS and Azure, full-stack development knowledge, database expertise, and strong technical leadership.

Own the AI product strategy and roadmap for HealthEdge’s HealthRules Payer platform. Identify and prioritize AI use cases across claims, member management, enrollment, benefits, and contracts; translate strategy into product requirements; and align product, engineering, data science, UX, marketing, and sales teams. Lead AI governance, regulatory compliance, customer presentations, go-to-market messaging, pilots, and feature commercialization while ensuring responsible AI use in healthcare payer workflows.

Lead the development of machine learning systems for Cedar Pay's Personalization Engine, manage ML engineers, and ensure ML model effectiveness.

Own the design vision and execution for experimental AI-powered learning tools co-created with teachers and researchers. Design teacher- and student-facing products, create flows, wireframes, interaction designs, and functional prototypes, and facilitate collaboration across educators, researchers, engineers, and data scientists. Conduct usability testing and validate research hypotheses while navigating ambiguity, data-heavy workflows, and uncertain AI/ML-enabled features.

Leads enterprise manufacturing AI, machine learning, and Industry 4.0 initiatives across multiple plants. Develops and deploys solutions for predictive maintenance, process and quality optimization, energy efficiency, throughput, and OEE improvement. Establishes scalable data and AI platforms, governance, and MLOps standards while integrating industrial data sources. Leads and mentors data science teams, prioritizes projects, allocates resources, partners with cross-functional manufacturing stakeholders, and presents strategic recommendations and business cases to executives.

Manage paid social campaigns and full-funnel strategies across Meta, LinkedIn, TikTok, Pinterest, Snapchat, and other paid channels. Oversee client accounts, analyze performance, identify growth opportunities, build client relationships, and collaborate with SEO, creative, and analytics teams. Contribute to thought leadership, coach associates, maintain quality standards, and explore automation, AI, and LLM search visibility initiatives.

Own the strategy, execution, customer success, and go-to-market for Oscilar’s Device and Behavior product. Lead development of SDKs, signal pipelines, behavioral biometrics, agentic identity signals, data networks, foundation-model capabilities, and analyst experiences. Partner with sales and customers to drive adoption, shape product positioning, and deliver a device intelligence and digital identity platform for fraud, onboarding, authentication, and risk decisions.

Supervise actuarial predictive modeling initiatives for insurance pricing, portfolio management, and planning. Collaborate with actuaries, data scientists, underwriters, and management to develop, validate, govern, and implement models. Establish assumptions, loss adjustments, usage guardrails, monitoring practices, and model documentation. Support regulatory filings, improve team workflows, contribute to strategic projects, and mentor staff in actuarial and technical skills.

Develop and maintain pricing and predictive models for credit insurance products. Analyze claims, loss ratios, portfolio performance, profitability, credit risk, and economic scenarios. Recommend pricing actions, support forecasting and reserves, evaluate underwriting strategies, and partner with underwriting, finance, claims, data science, and technology teams. Ensure model governance, documentation, and actuarial standards compliance.

Designs, builds, and operationalizes enterprise AI, generative AI, machine learning, and agentic AI solutions. Develops integrations, orchestration services, reusable tooling, deployment pipelines, monitoring, and governance controls. Partners with architecture, platform, data, and product teams to deliver scalable, secure, compliant AI capabilities across the organization.

Owns the strategy, roadmap, requirements, backlog, positioning, and lifecycle execution for proprietary software products. Partners with engineering, UX, QA, architecture, data operations, and project management teams in an Agile environment. Conducts market and competitive analysis, supports product launches, creates AI prototypes, develops client-facing content, and contributes to RFP responses. Requires strong technical, product leadership, communication, prioritization, and stakeholder-management skills.

The Staff Machine Learning Engineer will lead ML initiatives, develop ML systems, collaborate with cross-functional teams, and mentor junior engineers to optimize healthcare intake workflows using advanced machine learning techniques.

Lead and transform the Fraud Intelligence Team by designing scalable operating models, QA and measurement frameworks, and talent programs. Drive labeling quality, operational metrics, and fraud prevention impact; convert frontline fraud observations into insights for Product, R&D, Analytics, and GTM; leverage AI, automation, and tooling; and serve as a cross-functional fraud subject-matter expert while developing early-career talent and measurable business outcomes.

Build rigorous ROI analyses, value models, and business cases that translate AI ranking performance into revenue, margin, and cost-to-serve outcomes. Present analyses to CFOs, procurement teams, and other economic buyers; support sales pursuits; create reusable value-selling frameworks; tailor models to customer economics; and collaborate with product, data science, and customer teams to validate benchmarks and deployment results.

Own the full Global System Integrator partner lifecycle, including sourcing, agreements, joint go-to-market motions, enablement, delivery planning, and performance optimization. Build relationships across major GSIs such as Accenture, Deloitte, Bain, BCG, Slalom, and IBM. Collaborate with sales, product, and engineering teams to generate partner-sourced and influenced pipeline and revenue. Develop the GSI strategy, playbook, and operating processes for Sequen’s growing AI business.