Top Senior Machine Learning Jobs in San Diego, CA

20 Days AgoSaved
In-Office or Remote
San Diego, CA
160K-235K Annually
Senior level
160K-235K Annually
Senior level
Big Data • Software
Design, build, and productionize ML systems focused on information extraction, retrieval, ranking, and recommendation. Own full ML lifecycle from feature engineering to deployment, observability, and evaluation. Collaborate with data, infra, and product teams to scale serving for streaming and batch inference and improve models using dataset engineering and graph/embedding techniques.
Top Skills: A/B TestingCi/CdEmbedding ModelsGraph DatabasesLearn-To-RankMl Model ServingOcrPythonPyTorchScikit-LearnVector Databases
20 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Artificial Intelligence • Hardware • Software • Semiconductor
Design and implement system-level debugging, validation, and observability platforms. Build automated anomaly collection/analysis, visualization and root-cause tools, failure classification and monitoring frameworks. Extend compilers, runtimes and programming interfaces for profiling and instrumentation, improve bring-up and low-level debug workflows, lead cross-functional initiatives, support incident response, and establish debuggability and reliability best practices.
Top Skills: C++CompilersFirmwareHardware InterfacesInstrumentationProfilingProgramming InterfacesPythonRuntimesVisualization Tools
21 Days AgoSaved
Remote
San Diego, CA
150K-200K Annually
Senior level
150K-200K Annually
Senior level
Logistics • Transportation
Build and maintain data and model layers for an AI decision‑support system: data ingestion, probabilistic record matching, calibrated scoring, provenance‑tracked retrieval and grounded generation, and secure production pipelines. Ensure explainability, auditability, and accredited deployment in a controlled government cloud environment.
Top Skills: PythonSQL
21 Days AgoSaved
Remote
San Diego, CA
150K-200K Annually
Senior level
150K-200K Annually
Senior level
Fintech • Payments • Financial Services
Design and build data and model layers for an accredited AI decision-support system: record matching, calibrated scoring, provenance-tracked retrieval and generation, secure ingestion pipelines, model packaging/serving, and instrumentation for audit and accreditation.
Top Skills: AirflowApache NifiSparkAws GlueDbtEmbeddingsKafkaLanguage ModelsPgvectorPostgresPythonPyTorchRetrieval-Augmented GenerationScikit-LearnSQLVector StorageXgboost
21 Days AgoSaved
In-Office or Remote
San Diego, CA
121K-219K Annually
Senior level
121K-219K Annually
Senior level
Cloud • Security • Software • Cybersecurity
Build and operate model validation, quantization, and safety systems for production ML. Develop pipelines for security scanning, optimization (quantization/pruning), routing, prompt management, and evaluation frameworks measuring accuracy, performance, and safety across model lifecycles.
Top Skills: AwqCi/CdCloud InfrastructureContainerizationGgufGptqJaxLlmsPythonPyTorchTensorFlowTransformers
Reposted 21 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Artificial Intelligence • Healthtech • Software • Biotech
Lead design, development, and production deployment of ML models and GenAI/LLM solutions to optimize clinical trial workflows. Build scalable pipelines, monitoring, and CI/CD for robust production use. Collaborate cross-functionally, mentor junior engineers, and communicate technical results to technical and non-technical stakeholders.
Top Skills: Ci/CdCloud InfrastructureFine-TuningGenaiLarge Language Models (Llms)Ml PipelinesModel DeploymentModel MonitoringPythonSQL
Reposted 21 Days AgoSaved
Remote
San Diego, CA
151K-179K Annually
Senior level
151K-179K Annually
Senior level
Other
Lead and mentor engineering teams while owning platform architecture (React, Node/Express, Postgres, AWS). Drive TypeScript migration, design ETL and AI/LLM integration frameworks, ensure reliability and observability, manage delivery, incidents, and hiring, and define technical strategy for production ML/AI systems.
Top Skills: Aws EcsAws LambdaAws RdsAws S3ETLEvent-Driven ArchitectureExpressJavaScriptLlmMessage QueuesMl/AiNode.jsPostgresReactStreaming PipelinesTypescript
Reposted 22 Days AgoSaved
Remote
San Diego, CA
196K-227K Annually
Senior level
196K-227K Annually
Senior level
Real Estate • Travel • PropTech
Lead development and refinement of machine learning pricing models (especially reinforcement learning) for Airbnb hosts. Collaborate with data scientists, product, and engineers to design, test, integrate, and monitor models, analyze performance, and prioritize projects to improve host outcomes.
Top Skills: PythonReinforcement Learning
22 Days AgoSaved
Remote
San Diego, CA
159K-215K Annually
Senior level
159K-215K Annually
Senior level
Information Technology • Security • Software • Cybersecurity
Lead a 4-6 engineer team owning the internal data warehouse and end-to-end ML Ops lifecycle: experimentation, training pipelines, deployment, and monitoring. Provide technical leadership, collaborate with cross-functional partners, define platform standards, and coach engineers to deliver reliable, scalable data and ML infrastructure that powers product analytics and identification features.
Top Skills: AWSAws SagemakerBigQueryClickhouseDatabricksDatahubDbtPrefectSnowflake
22 Days AgoSaved
Remote
San Diego, CA
466K-750K Annually
Senior level
466K-750K Annually
Senior level
News + Entertainment
Build and prototype supervised ML models to predict ad campaign delivery outcomes (reach, frequency, contention). Own feature engineering, evaluation frameworks, interpretability, and partner with ML engineers to deploy and monitor models at scale. Collaborate across product, engineering, and sales to drive adoption and measure lift versus simulation baselines.
Top Skills: Feature StoreGenaiGradient-Boosted TreesMetaflowPythonSQL
22 Days AgoSaved
Remote
San Diego, CA
235K-285K Annually
Senior level
235K-285K Annually
Senior level
Automotive • Machine Learning • Robotics • Software • Transportation
Lead the design and delivery of a production-grade localization ML stack for autonomous vehicles: architect models for landmark-based localization across sensors, own data and evaluation pipelines, drive feature development to deployment, define failure modes and safety coverage, and mentor engineers while integrating cutting-edge multimodal and foundation-model techniques into robust, real-time localization systems.
Top Skills: 3D ReconstructionActive LearningBev (Bird'S Eye View)C++Camera/ImageryDepth EstimationFoundation ModelsLidarLinuxObject DetectionOrbPruningPythonPyTorchQuantizationRadarSegmentationSensor FusionSiftSlamSuperpointSynthetic Data GenerationTensorFlowTrackingTransformersVision-Language Models
22 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Artificial Intelligence • Big Data • Machine Learning
Design and deliver enterprise-grade Generative AI solutions on AWS using Bedrock and AgentCore. Architect LLM-based applications, RAG pipelines, agentic workflows, vector DB integrations, and APIs. Optimize models for performance, cost, and quality, ensure security and governance, lead teams, and troubleshoot production GenAI systems.
Top Skills: Amazon AgentcoreAmazon Api GatewayAmazon S3Apache AirflowAws BedrockAws LambdaAws SagemakerAws Step FunctionsCi/CdEmbeddingsIacKubeflowLangchainLlm Apis (ClaudeModel Context Protocol (Mcp)Nova)Prompt EngineeringRetrieval-Augmented Generation (Rag)Sagemaker PipelinesStrand AgentsVector Databases
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22 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Artificial Intelligence • Big Data • Machine Learning
Architect and implement enterprise-grade MLOps/LLMOps platforms on AWS and Kubernetes. Design ML/LLM pipelines for training, validation, deployment, monitoring, governance, CI/CD, and observability. Serve as technical authority, conduct architecture reviews, ensure security and compliance, and mentor engineering teams across projects.
Top Skills: AgentcoreAirflowApi GatewayAWSAws BedrockBentomlCdkCi/CdCloudwatchCodebuildCodepipelineDatabricksEksGrafanaHelmIamKserveKubeflowKubernetesLambdaLlmopsMlflowOpentelemetryPrometheusPythonSagemakerSagemaker Feature StoreSagemaker Model MonitorSagemaker Model RegistrySagemaker PipelinesSecrets ManagementSeldonSnowflakeSparkSQLTerraform
22 Days AgoSaved
Remote
San Diego, CA
160K-190K Annually
Senior level
160K-190K Annually
Senior level
Automotive • Information Technology • Software
Design, build, and operate production agentic AI systems on AWS Bedrock AgentCore using Strands/LangGraph. Implement tool integrations (MCP/Gateway), evaluation pipelines and LLM-as-judge CI gates, observability, cost/latency controls, and guardrails for agents operating on live dealer data.
Top Skills: Agentcore GatewayAgentcore RuntimeAnthropic HaikuAnthropic OpusAnthropic SonnetApi GatewayAthenaAuroraAws BedrockAws CdkAws EventbridgeAws LambdaBedrock AgentcoreBedrock GuardrailsCloudwatchData LakeDynamoDBEcs FargateETLGlueGoogle AdkJavaLanggraphMcp (Model Context Protocol) ServersOpenai Agents SdkOpentelemetryPythonRestS3SoapSpring BootStep FunctionsStrandsStrands Agents Sdk
Reposted 23 Days AgoSaved
Remote
San Diego, CA
97K-165K Annually
Senior level
97K-165K Annually
Senior level
Financial Services
Design, develop, implement, and monitor statistical and machine learning models to support credit risk, collections, servicing, marketing, and forecasting. Build data pipelines, translate business needs into analytical solutions, support model governance, testing, deployment, and ongoing performance monitoring, and communicate results to stakeholders.
Top Skills: PythonRSASSQL
Reposted 23 Days AgoSaved
Remote
San Diego, CA
158K-170K Annually
Senior level
158K-170K Annually
Senior level
Financial Services
Lead development and deployment of predictive and ML models for credit risk, collections, and operations. Mentor data scientists, promote MLOps and modern tools, present insights to stakeholders, and drive experimentation with techniques such as causal inference and GenAI.
Top Skills: Causal InferenceDeep LearningEnsemble ModelsExplainabilityGenerative AiMlopsModel GovernanceNlpPythonRResponsible AiSASSQL
Reposted 23 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Artificial Intelligence • Machine Learning
Partner with customers to design and deliver production-ready AI/ML solutions, drive POC-to-production success, troubleshoot technical issues, inform product roadmap with customer feedback, and communicate outcomes to stakeholders.
Top Skills: Agent FrameworksAWSAzureGCPKubernetesLlmsMlopsPythonVector Dbs
Reposted 23 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Artificial Intelligence • Software
The Senior Data Engineer will own the data strategy, managing sourcing, structuring, and optimizing multimodal data to enhance AI models and products.
Top Skills: Large-Scale Data ProcessingPythonSQL
Reposted 23 Days AgoSaved
Remote
San Diego, CA
220K-260K Annually
Senior level
220K-260K Annually
Senior level
Artificial Intelligence • Marketing Tech • Mobile • Software
As a Senior Software Engineer, you'll build and operate the ML platform, optimizing data operations, managing the feature store, and supporting ML initiatives while driving architectural roadmap decisions.
Top Skills: AirflowSparkAWSCloudflareDynamoDBGradleGraphQLHuggingfaceJavaKafkaKinesisKubernetesMetaflowPandasPlanetscalePlaywrightPostgresPythonPyTorchRayReactRedisSpark Structured StreamingSpring BootTensorFlowTerraformTypescriptVite
Reposted 23 Days AgoSaved
Remote
San Diego, CA
260K-310K Annually
Senior level
260K-310K Annually
Senior level
Artificial Intelligence • Marketing Tech • Mobile • Software
The Staff Engineer will architect and build AI and ML infrastructures, mentor engineers, and lead high-impact initiatives to enhance ML capabilities across Attentive's platform.
Top Skills: ArgoKubeflowMetaflowMlflowPythonRaySpark
Reposted 23 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Healthtech • Software • Database • Biotech • Pharmaceutical
As a Senior Machine Learning Engineer, you will develop and deploy AI-driven products to enhance clinical trials, collaborating with teams to improve patient care through scalable machine learning solutions.
Top Skills: AthenaAWSBedrockCi/CdClojureDbtPandasPrefectPythonPyTorchSagemakerScikit-LearnTensorFlow
Reposted 23 Days AgoSaved
Remote
San Diego, CA
141K-208K Annually
Senior level
141K-208K Annually
Senior level
Database • Analytics
Own and evolve ClickHouse's Python connector and SDKs; build and maintain integrations with orchestration and transformation tools; design AI/LLM integration patterns (RAG, embeddings, feature stores); engage with open-source community; collaborate with Product and Cloud teams to prioritize and ship production-grade data integrations.
Top Skills: Apache AirflowApache FlinkSparkAsyncClickhouseDagsterDbtFivetranKafka ConnectLangchainLlamaindexMultiprocessingN8NNumpyPandasPrefectPydanticPythonSQLSqlmeshThreading
Reposted 23 Days AgoSaved
Remote
San Diego, CA
141K-195K Annually
Senior level
141K-195K Annually
Senior level
Database • Analytics
Develop AI/ML-powered features in ClickHouse Cloud, focusing on frontend and API architecture, UI/UX, and integrations with AI systems.
Top Skills: AWSAzureClickhouseGCPJavaScriptPythonReactTypescript
Reposted 24 Days AgoSaved
Remote
San Diego, CA
196K-227K Annually
Senior level
196K-227K Annually
Senior level
Real Estate • Travel • PropTech
Lead development of cutting-edge LLM and Agentic AI systems for Airbnb customer support, from research and prototyping to production deployment. Collaborate with product, design, and engineering to build scalable ML infrastructure, improve model performance, and implement evaluation, fine-tuning, and guardrails for chat and voice assistants.
Top Skills: Agentic AiAutogenDistillationGrpoLanggraphLlmLlm Evaluation FrameworksMl InfrastructureMlopsModel ServingMulti-Agent OrchestrationPretrainingPrompt EngineeringRagReactRlhfSft
Reposted 25 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Artificial Intelligence • Healthtech • Machine Learning
Develop and tune ML models, productionize and deploy strategies for ML systems, and align cross-functionally to communicate performance metrics.
Top Skills: PysparkPythonPyTorchSQL
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