Top Senior Machine Learning Jobs in San Diego, CA

Reposted One Month AgoSaved
Remote
San Diego, CA
150K-165K Annually
Senior level
150K-165K Annually
Senior level
Healthtech
Lead program delivery for engineering teams at Arine, optimizing internal processes and ensuring timely execution of technical programs while facilitating Agile methodologies.
Top Skills: AgileAIConfluenceData ScienceJIRAMachine LearningSaaS
21 Days AgoSaved
In-Office
San Diego, CA
125K-235K Annually
Senior level
125K-235K Annually
Senior level
Aerospace • Logistics • Security • Software • Cybersecurity
Design and build custom ML and statistical solutions for product support analytics. Collaborate with engineers and analysts, architect data pipelines, write modular tested code, implement CI/CD, optimize algorithms on on-prem infrastructure, and document workflows while championing software engineering best practices in the data domain.
Top Skills: CC++Ci/CdDockerGitMlopsNumpyPandasPythonPyTorchScikit-LearnSQLSqlalchemy
21 Days AgoSaved
In-Office
San Diego, CA
110K-180K Annually
Senior level
110K-180K Annually
Senior level
Information Technology • Consulting • Cybersecurity • Defense
Design, develop, and deploy machine learning models and data pipelines for naval applications. Build and optimize distributed, cloud-native analytics and event-streaming systems, work with multiple data formats and GIS tools, containerize and monitor deployments, apply DoD security practices, and collaborate with multidisciplinary teams to deliver mission-ready AI solutions in shipboard and operational Navy environments.
Top Skills: AirbyteApache AirflowApache IcebergApache KafkaArcgisAWSAws KinesisAws LambdaAws S3AzureC++CsvDaskDbtDockerEfsGitGithub ActionsGitlab CiGoJavaJenkinsJSONKubernetesOrcParquetPostgisPythonPyTorchRabbitMQRdsRustScikit-LearnSnowflakeSnsSparkSqsTensorFlowXMLZeromq
21 Days AgoSaved
In-Office
San Diego, CA
165K-195K Annually
Senior level
165K-195K Annually
Senior level
Information Technology • Consulting • Cybersecurity • Defense
Design, develop, and deploy advanced machine learning models for naval applications. Build cloud-native ML pipelines, apply distributed computing and MLOps/CI-CD practices, integrate models into operational DoD environments, and produce technical documentation per government standards. Collaborate with multidisciplinary teams and apply cybersecurity principles for secure shipboard and edge deployments.
Top Skills: AWSAzureC++DockerGitGithub ActionsGitlab CiGoJavaJenkinsKubernetesPythonPyTorchRustScikit-LearnTensorFlow
Reposted 11 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Machine Learning • Software
As a Staff Data Scientist, you will lead initiatives to build and optimize machine learning models, collaborate across departments, and solve complex business problems using data.
Top Skills: LlmMlSQL
Reposted 11 Days AgoSaved
Remote
San Diego, CA
165K-259K Annually
Senior level
165K-259K Annually
Senior level
Big Data • Information Technology • Machine Learning • Sales • Software • Database • Generative AI
As a Senior Machine Learning Engineer at ZoomInfo, you will enhance core datasets through ML/NLP solutions, manage entity resolution tasks, and drive cross-functional impact by mentoring teams and collaborating on ML KPIs.
Top Skills: BertGoGptGraph RagJavaPythonPyTorchRagT5TensorFlowTransformerVector Dbs
Reposted 11 Days AgoSaved
Remote
San Diego, CA
112K-210K Annually
Senior level
112K-210K Annually
Senior level
Artificial Intelligence • Software
Develop and iterate deep learning models for protein-ligand co-folding and structure prediction, benchmark performance, integrate validated models into production drug-discovery pipelines, analyze structural and sequence data, communicate findings, and collaborate with multidisciplinary teams to scale research into products.
Top Skills: Alphafold2Alphafold3AWSAzureBoltzChai-1Claude CodeCodexDiffusion ModelsEquivariant Neural NetworksGCPGenerative ModelsJaxPythonPyTorchQsarRosettafoldTransformers
Reposted 11 Days AgoSaved
Remote
San Diego, CA
143K-197K Annually
Senior level
143K-197K Annually
Senior level
Healthtech • HR Tech
Lead design, training, fine-tuning, and deployment of ML and generative models (LLMs, diffusion). Build scalable MLOps pipelines, vectorization and data ingestion, integrate models into microservices for low-latency inference, implement evaluation/alignment/bias-mitigation, optimize models (quantization, distillation), and mentor engineers while influencing the AI product roadmap.
Top Skills: AWSCeleryDiffusion ModelsDistillationDockerJavaKotlinKubernetesLlmsLow-Latency DatabasesMicroservicesMlops FrameworksProtobufPythonQuantizationRagRelational DatabasesVector Databases
Reposted 11 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Fintech • Software
Build and design backend services, AI agents, and machine learning models. Collaborate cross-functionally to deliver AI features and maintain code quality.
Top Skills: AWSFastapiHugging FacePythonPyTorchScikit-Learn
Reposted 11 Days AgoSaved
Remote
San Diego, CA
135K-165K Annually
Senior level
135K-165K Annually
Senior level
eCommerce • Insurance • Software
The Senior ML Data Scientist will develop machine learning models to detect fraud, manage the data science lifecycle, and collaborate with teams on strategies.
Top Skills: AWSPythonPyTorchScikit-LearnSQLXgboost
22 Days AgoSaved
In-Office or Remote
San Diego, CA
259K-424K Annually
Senior level
259K-424K Annually
Senior level
Cloud • Information Technology • Internet of Things • Professional Services • Software
Lead research, design, and deployment of large-scale foundation models for machine-generated data (logs, time series, traces). Define AI strategy, mentor senior engineers, partner with product and exec teams, and drive production-grade model training, optimization, and MLOps for enterprise-scale applications.
Top Skills: BertDeep LearningDistributed TrainingGptLlamaMlopsPythonPyTorchT5TensorFlow
Reposted 12 Days AgoSaved
Remote
San Diego, CA
175K-190K Annually
Senior level
175K-190K Annually
Senior level
AdTech • Marketing Tech
Design, build, and deploy production-grade AI/ML and LLM-based systems. Lead end-to-end ML lifecycle, implement RAG and embedding pipelines, establish MLOps best practices, mentor engineers, and collaborate with cross-functional teams to deliver scalable, responsible AI solutions.
Top Skills: AWSAzureAzure MlBedrockCi/CdDatabricksDpoEmbeddingsExperiment TrackingHuggingfaceLlmMlopsPythonPyTorchRagRlSagemakerSftSnowflakeSQLVector SearchVector Stores
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Reposted 12 Days AgoSaved
Remote
San Diego, CA
180K-225K Annually
Senior level
180K-225K Annually
Senior level
Big Data • HR Tech • Mobile • Software • Database
Lead design, development, and productionization of advanced ML models and data pipelines. Drive architecture, experimentation, validation, and best practices while mentoring ML engineers and delivering scalable, business-driving AI solutions.
Top Skills: BertConvolutional Neural Networks (Cnn)Generative Adversarial Networks (Gan)LstmNltkPyTorchRecurrent Neural Networks (Rnn)Scikit-LearnSpacyTensorFlow
Reposted 12 Days AgoSaved
Remote
San Diego, CA
174K-224K Annually
Senior level
174K-224K Annually
Senior level
Fintech
The Lead Machine Learning Scientist will develop and implement ML strategies to enhance marketing and product capabilities, identify opportunities for growth using data, lead core model development, and improve marketing spend efficiency through insights and experimentation.
Top Skills: PythonPyTorchScikit-LearnSnowflakeSQLTensorFlow
Reposted 12 Days AgoSaved
Remote
San Diego, CA
160K-220K Annually
Senior level
160K-220K Annually
Senior level
Big Data • Cybersecurity
Design and operate production ML systems for large-scale streaming data, ensuring reliability and performance while collaborating with researchers to integrate models into distributed systems.
Top Skills: FlinkJavaScriptKubernetesPandasPythonPyTorchScikit-LearnSparkTypescript
Reposted 12 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Artificial Intelligence • Software • Cybersecurity
Lead design and delivery of scalable AI systems for autonomous threat detection and response. Build and productionize LLMs, graph reasoning engines, streaming feature pipelines, and orchestration frameworks. Own evaluation, reliability, and cross-functional collaboration while mentoring engineers and experimenting with RAG, tool-calling agents, and multi-modal models.
Top Skills: Agno AgiDockerEvent-Driven SystemsFine-TuningGoGraph DatabasesGraph-Based Reasoning EnginesGrpcJavaKubernetesLangchainLanggraphLarge-Scale LlmsMicroservicesMulti-Agent Systems (Mas)Multi-Modal ModelsPrompt EngineeringPythonRestRetrieval-Augmented Generation (Rag)RustStreaming Feature PipelinesTool-Calling Agents
Reposted 12 Days AgoSaved
In-Office or Remote
San Diego, CA
190K-332K Annually
Senior level
190K-332K Annually
Senior level
Social Media
Lead Responsible AI projects to detect, mitigate, and evaluate bias across GenAI, foundation models, and recommender systems. Collaborate with product and platform teams, deploy fairness interventions at scale, mentor junior engineers, and define technical strategy to align models with Pinterest policies and business metrics.
Top Skills: Foundation Model Fine-TuningGenerative AiLlmsMl FairnessRed TeamingSearch And Recommender SystemsTransformer-Based ModelsTwo-Tower ArchitecturesVlms
Reposted 12 Days AgoSaved
Remote
San Diego, CA
225K-280K Annually
Senior level
225K-280K Annually
Senior level
Artificial Intelligence • eCommerce • Software
The Machine Learning Engineer will design and build systems that improve the AI shopping agent by using real user feedback, focusing on feedback loops and metrics to enhance user interactions and agent performance.
Top Skills: Machine Learning ToolingPython
Reposted 12 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Information Technology • Software • Consulting
Design, build, and deploy scalable ML models and pipelines to enhance a talent marketplace and GenAI solutions. Lead experimentation (A/B tests, statistical validation), improve production ML performance, ensure code and data quality, work with cross-functional teams, mentor junior engineers, and propose innovative AI-driven solutions aligned to business goals.
Top Skills: AWSAzureGCPGenerative AiPythonPyTorchScikit-LearnTensorFlow
Reposted 12 Days AgoSaved
Remote or Hybrid
San Diego, CA
172K-225K Annually
Senior level
172K-225K Annually
Senior level
Artificial Intelligence • Automotive • Machine Learning • Transportation
Lead technical roadmap and architecture for ML data infrastructure supporting petabyte-scale pipelines. Manage and mentor engineering team, design ingestion/transformation/serving systems, ensure data quality, lineage, governance, and collaborate with ML and infrastructure teams to deliver production-grade ML data pipelines and feature stores.
Top Skills: AWSAzureBeamDistributed DatabasesFeature StoresFlinkGCPSpark
Reposted 22 Days AgoSaved
Hybrid
San Diego, CA
242K-333K Annually
Senior level
242K-333K Annually
Senior level
Artificial Intelligence • Machine Learning • Robotics • Software • Transportation • Design • Manufacturing
The role involves leading machine learning initiatives to enhance automated testing for autonomous vehicles, improve model interpretability, and collaborate with cross-functional teams.
Top Skills: JaxPythonPyTorchSQLTensorFlow
One Month AgoSaved
In-Office or Remote
San Diego, CA
150K-190K Annually
Senior level
150K-190K Annually
Senior level
Artificial Intelligence • Legal Tech • Natural Language Processing • Generative AI
Own end-to-end client relationships for a book of B2B SaaS customers: drive adoption, engagement, retention, and expansion of AI-powered contract drafting tools. Lead onboarding, training, large-scale rollouts, and translate customer feedback into product improvements while designing scalable CS processes and tracking health metrics to demonstrate value.
Top Skills: AIGenerative AiLanguage AnalyticsMachine Learning
Reposted 13 Days AgoSaved
Remote
San Diego, CA
221K-405K Annually
Senior level
221K-405K Annually
Senior level
Social Media • Software
As a Senior Machine Learning Engineer, you will design and maintain ML systems for content recommendations, search, and spam detection, while augmenting user experience and system performance.
Top Skills: BigQueryGoPostgresPythonPyTorchRay
Reposted 13 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Cloud • Information Technology • Software • Cybersecurity
The AI/Machine Learning Engineer will develop systems for automating health benefits decisions, integrating large language models with rule-driven patterns, and ensuring compliance with regulations.
Top Skills: Azure Ai ServicesAzure Machine LearningCrewaiLangchainLanggraphPysparkPythonPyTorchScikit-LearnSemantic KernelSparkSQLTensorFlow
Reposted 13 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Big Data • Analytics • Business Intelligence • Big Data Analytics
The Machine Learning Engineer will develop software solutions, optimize data pipelines, and deploy machine learning models using cloud platforms and best practices.
Top Skills: AzureAzuremlDatabricksDockerMlflowPythonSpark
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