Top Senior Machine Learning Jobs in San Diego, CA

Reposted 25 Days AgoSaved
In-Office or Remote
San Diego, CA
140K-180K Annually
Senior level
140K-180K Annually
Senior level
Artificial Intelligence • Legal Tech • Natural Language Processing • Generative AI
Lead technical pre-sales and enterprise rollouts by owning infrastructure strategy, PoCs, migrations (on‑prem to cloud), DMS/CRM integrations, InfoSec discussions, and stakeholder engagement with C-level sponsors to enable scalable deployments and upsell opportunities.
Top Skills: Cloud InfrastructureCRMDevsecopsDocument Management SystemsGenerative AiImanageLarge Language ModelsMachine LearningMicrosoft Word
Reposted 25 Days AgoSaved
Remote
San Diego, CA
137K-152K Annually
Senior level
137K-152K Annually
Senior level
Healthtech • HR Tech • Sales • Social Impact • Software
As a Senior Data Scientist, you will identify business opportunities, build machine learning solutions, partner cross-functionally, and translate analyses into actionable insights.
Top Skills: Business Intelligence ToolsMachine LearningPythonRSQL
Reposted 25 Days AgoSaved
Remote or Hybrid
San Diego, CA
104K-154K Annually
Senior level
104K-154K Annually
Senior level
Consumer Web • eCommerce • Fashion • Retail
The Senior Manager will oversee the fraud lifecycle, optimize detection strategies, conduct fraud reviews, collaborate with teams, and manage risk reporting.
Top Skills: AIMachine LearningSnowflakeSQL
Reposted 25 Days AgoSaved
Remote
San Diego, CA
200K-225K Annually
Senior level
200K-225K Annually
Senior level
Artificial Intelligence • eCommerce • Software
Design and build backend systems and APIs for AI-driven products, ensuring scalability, reliability, and integration of ML models while collaborating with engineering and product teams.
Top Skills: APIsAWSAzureDockerGCPKubernetesLlmsMachine LearningNoSQLPythonSQL
Reposted 2 Days AgoSaved
Remote
San Diego, CA
161K-225K Annually
Senior level
161K-225K Annually
Senior level
Information Technology • Software
The role involves leading ML strategy, architecting systems, designing algorithms, collaborating with teams, and mentoring engineers in AI for enterprise analytics.
Top Skills: FlinkJavaPythonRaySpark
25 Days AgoSaved
Remote or Hybrid
San Diego, CA
Senior level
Senior level
Fintech • Financial Services
Lead design and scaling of a unified fraud and risk platform. Own roadmap, fraud metrics, SQL-based analysis, A/B testing, real-time detection models, and cross-functional delivery to balance customer experience and risk mitigation.
Top Skills: A/B TestingAPIsArtificial IntelligenceBlockchainData PipelinesMachine LearningRiskifiedSardineSQL
25 Days AgoSaved
Remote
San Diego, CA
85K-110K Annually
Senior level
85K-110K Annually
Senior level
AdTech • Agency • Marketing Tech • Social Media
Lead analyses measuring campaign impact, build tagging models (prompt engineering and ML), synthesize insights across programs, analyze experiments including RCTs, and produce presentations and post-campaign reports for internal teams and clients.
Top Skills: BigQueryGCPMachine LearningNatural Language ProcessingPrompt EngineeringPythonRSQL
25 Days AgoSaved
Remote
San Diego, CA
150K-200K Annually
Senior level
150K-200K Annually
Senior level
Cloud • Software • Transportation
Lead North America revenue growth by building relationships, managing pipeline, responding to RFPs/RFIs, coordinating cross-functional teams, tracking activity in Salesforce, representing Optibus at industry events, and delivering data-driven sales forecasts.
Top Skills: AIMachine LearningOptimization AlgorithmsSalesforce
2 Days AgoSaved
Remote
San Diego, CA
200K-235K Annually
Senior level
200K-235K Annually
Senior level
Real Estate • Travel • PropTech
Build and productionize large-scale ML models and pipelines for query understanding and personalization. Work on autocomplete, query tagging/NER, query expansion, intent modeling, and LLM-powered natural-language search. Collaborate cross-functionally to design, deploy, and monitor batch and real-time systems, leveraging modern ML infrastructure and tooling to improve search relevance across Airbnb products.
Top Skills: AirflowC++HiveJavaKafkaKubernetesLarge Language Models (Llms)PythonPyTorchScalaSparkTensorFlow
Reposted 2 Days AgoSaved
In-Office or Remote
San Diego, CA
150K-300K Annually
Senior level
150K-300K Annually
Senior level
AdTech • Artificial Intelligence • Information Technology • Mobile • Software
The Senior Machine Learning Engineer will design, train, and deploy ML models for optimizing revenue in advertising, taking ownership of product development and leading the ML discipline.
Top Skills: AWSClickhouseDatadogGoKubernetesLightgbmOnnxPythonXgboost
Reposted 2 Days AgoSaved
Remote
San Diego, CA
220K-270K Annually
Senior level
220K-270K Annually
Senior level
Automotive • Machine Learning • Robotics • Software • Transportation
The Lead Machine Learning Engineer will design and evaluate models for autonomous driving systems, mentor junior engineers, and utilize large datasets to improve ML capabilities at May Mobility.
Top Skills: CameraLidarLinuxPythonPyTorchRadar
Reposted 2 Days AgoSaved
Remote
San Diego, CA
175K-220K Annually
Senior level
175K-220K Annually
Senior level
Artificial Intelligence • Fintech • Machine Learning • Software • Financial Services
Lead the development of device intelligence and fingerprinting systems by designing backend services, collaborating on integrations, and applying advanced machine learning algorithms to enhance security and combat fraud.
Top Skills: AWSAzureDockerGoGCPKubernetesPyTorchScikit-LearnSQL
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Reposted 2 Days AgoSaved
Remote
San Diego, CA
178K-198K Annually
Senior level
178K-198K Annually
Senior level
Healthtech • Software
The role involves applying AI/ML techniques to develop model systems for healthcare, collaborating across teams, and conducting R&D.
Top Skills: SparkAWSAzureAzure Data LakeDatabricksGCPHugging Face TransformersJavaLightgbmNumpyPandasPythonPyTorchScikit-LearnScipySQL
Reposted 2 Days AgoSaved
Remote
San Diego, CA
163K-218K Annually
Senior level
163K-218K Annually
Senior level
Internet of Things
Design, fine-tune, evaluate, and deploy LLM-driven, user-facing browser features using RAG, embeddings, prompt engineering, and modern ML tooling. Lead end-to-end model lifecycle, run production experiments, collaborate with product and engineering, and document and review work with an emphasis on privacy, latency, and usability.
Top Skills: Browser Web TechnologiesClassificationEmbedding-Based RetrievalGenerative AiHugging FaceIntent ModelingLangchainLarge Language Models (Llms)Natural Language Processing (Nlp)On-Device Model OptimizationPrivacy-Preserving MlPrompt EngineeringRayRetrieval-Augmented Generation (Rag)SummarizationWeights & Biases
Reposted 25 Days AgoSaved
Remote
San Diego, CA
175K-190K Annually
Senior level
175K-190K Annually
Senior level
Healthtech • Biotech
The role oversees analytical characterization and comparability studies for biologics, ensuring regulatory compliance and leadership in product development.
Top Skills: Artificial IntelligenceBiophysical AssaysChromatographic MethodsFunctional AssaysMachine LearningMass Spectrometry
3 Days AgoSaved
Remote
San Diego, CA
220K-290K Annually
Senior level
220K-290K Annually
Senior level
Information Technology • Software
Build and productionize ML models and data infrastructure to analyze millions of chaos engineering experiments, detect and explain failures, recommend automated remediation, and integrate AI-driven failure analysis into Gremlin's product using techniques like causal inference, graph ML, time-series modeling, and reinforcement learning.
Top Skills: Agentic AiCausal InferenceChaos EngineeringData PipelinesFeature StoresGraph MlMlopsModel MonitoringModel ServingReinforcement LearningSite Reliability EngineeringTime-Series Modeling
3 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Artificial Intelligence • Machine Learning • Professional Services • Business Intelligence • Big Data Analytics
Lead client-facing architecture and delivery of production-grade GenAI systems. Design scalable LLM, agentic, RAG, recommender, and LTR solutions, manage client engagements, mentor ML engineering teams, and oversee project lifecycle from discovery to deployment and monitoring.
Top Skills: AWSCatboostCommercial LlmsDockerFastapiGCPKubeflowLangchainLangfuseLanggraphLightgbmLlamaindexMlflowNumpyOpen-Source LlmsPandasPythonScikit-LearnTensorFlow
Reposted 3 Days AgoSaved
In-Office or Remote
San Diego, CA
152K-288K Annually
Senior level
152K-288K Annually
Senior level
Artificial Intelligence • Computer Vision • Hardware • Robotics • Metaverse
Develop algorithms and optimizations for inference and compiler stack, enhance performance metrics, collaborate with hardware teams, and publish work on novel approaches.
Top Skills: C/C++LlvmMlirOnnxPyTorchRustTensorFlow
Reposted 3 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Machine Learning • Software
Develop, evaluate, and deploy AI systems and machine learning models, focusing on NLP and multimodal models. Collaborate with teams and publish research.
Top Skills: Information RetrievalLarge Language ModelsNatural Language ProcessingPandasRetrieval-Augmented GenerationTorchTransformersTransformers
Reposted 3 Days AgoSaved
Remote
San Diego, CA
180K-200K Annually
Senior level
180K-200K Annually
Senior level
Artificial Intelligence • Software
The Senior ML Engineer will automate component placement on PCBs, working on R&D and production using ML and optimization techniques.
Top Skills: Cuda C++PyTorch
Reposted 3 Days AgoSaved
Remote
San Diego, CA
180K-200K Annually
Senior level
180K-200K Annually
Senior level
Artificial Intelligence • Software
As a Senior/Staff ML Systems Engineer at Quilter, you'll design and maintain ML infrastructure for automated PCB component placement, manage data pipelines, and lead systems design reviews while ensuring project efficiency and reliability within a fully distributed team.
Top Skills: AICi/CdHigh-Performance ComputingMl
Reposted 3 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Artificial Intelligence • Other • Sales • Software
As a Senior Machine Learning Engineer, develop LLM evaluation frameworks and agentic AI workflows to extract insights from conversations and optimize customer experiences.
Top Skills: Hugging FaceLlmNlpNltkPyTorchSpacyTensorFlow
Reposted 3 Days AgoSaved
Remote
San Diego, CA
196K-227K Annually
Senior level
196K-227K Annually
Senior level
Real Estate • Travel • PropTech
Lead development of cutting-edge LLM and Agentic AI systems for Airbnb customer support, from research and prototyping to production deployment. Collaborate with product, design, and engineering to build scalable ML infrastructure, improve model performance, and implement evaluation, fine-tuning, and guardrails for chat and voice assistants.
Top Skills: Agentic AiAutogenDistillationGrpoLanggraphLlmLlm Evaluation FrameworksMl InfrastructureMlopsModel ServingMulti-Agent OrchestrationPretrainingPrompt EngineeringRagReactRlhfSft
Reposted 3 Days AgoSaved
Remote
San Diego, CA
119K-217K Annually
Senior level
119K-217K Annually
Senior level
Kids + Family • Mobile
Build and operate high-throughput experimentation and recommendation infrastructure. Design APIs and services, use agentic AI workflows (LLMs) for development, ensure performance and reliability, participate in on-call, mentor teammates, and codify AI-native engineering practices.
Top Skills: Apache KafkaAWSClaude CodeConfluent CloudConfluent PlatformContainerized DeploymentsCursorDatadogFeature StoresFlinkGithub ActionsGithub CopilotGrafanaJavaKafka StreamsLlmsMavenNexusPrometheusSchema RegistrySpring Boot
4 Days AgoSaved
Remote
San Diego, CA
150K-187K Annually
Senior level
150K-187K Annually
Senior level
Fintech
Build and evolve core ML platform infrastructure—feature stores, real-time scoring, deployment, monitoring, and data access. Drive architecture and technical decisions, ensure reliability at scale, mentor engineers, partner with data scientists, and lead complex projects from design to production.
Top Skills: AirflowApache BeamArgocdBigQueryBigtableDatadogDockerFastapiFirestoreGoogle Cloud StorageJavaKubernetesNode.jsPub/SubPythonRedisSnowflakeSQLTerraformVertex Ai
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