Top Senior IT Jobs in San Antonio, TX

Reposted YesterdaySaved
Remote
San Antonio, TX
Senior level
Senior level
Healthtech
The Senior IT Program Manager leads program development and implementation, ensuring projects align with business needs and are delivered on time and budget. They manage stakeholder relationships and facilitate communication with senior leadership, oversee financial management, and develop risk management strategies.
Top Skills: ConfluenceJIRAMicrosoft ProjectMS OfficeSnow Spm
Reposted YesterdaySaved
Remote
San Antonio, TX
140K-150K Annually
Senior level
140K-150K Annually
Senior level
Healthtech • Pharmaceutical
The IT Systems Engineer III will improve Ophelia's IT systems through integration, automation, and security while managing IT projects, overseeing service providers, and ensuring compliance.
Top Skills: AIDlpDns AdministrationEdrGoogle Cloud PlatformIdp/IamItsmMdmSAMLScimZtna
2 Days AgoSaved
Remote
San Antonio, TX
98K-132K Annually
Senior level
98K-132K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Support CMS QPP/MIPS quality measurement efforts by designing and reviewing documentation, training, policy analysis, and technical assistance. Partner with clinical teams on requirements, testing, and implementation, analyze measure data and specifications (claims, QRDA/DEQM, HL7), produce reports and guidance, and liaise with stakeholders to resolve policy and technical issues.
Top Skills: ConfluenceCptDeqmHl7Icd-10JIRAMipsExcelMs PowerpointMs WordPdfQcdrQppQrdaRxnormSnomed
2 Days AgoSaved
Remote
San Antonio, TX
140K-170K Annually
Senior level
140K-170K Annually
Senior level
Artificial Intelligence • Insurance • Software • Automation
Provide senior-level remote IT support and operations for a distributed workforce: troubleshoot macOS/Windows/Linux/mobile, manage onboarding/offboarding, administer identity (Rippling/Okta) and MDM, maintain asset inventory, build AI-driven automations (Console.com, Risotto, Unthread), support SOC 2/HIPAA/ISO compliance, write runbooks in Notion, and contribute to the IT roadmap while mentoring the team.
Top Skills: 1PasswordClaudeConsole.Com (Aria)Google WorkspaceLinuxmacOSMfaMobileNotionOauthOktaRipplingRisottoSAMLScimShell ScriptingSlackSnipe-ItSsoUnthreadWindowsZoom
Reposted 2 Days AgoSaved
Remote
San Antonio, TX
143K-190K Annually
Senior level
143K-190K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Design, build, and operate production-ready distributed systems and microservices. Deliver new features, improve reliability and scalability, identify bottlenecks, mentor junior engineers, and contribute to architecture and modernization efforts.
Top Skills: Ai/Automation ToolsAsynchronous SystemsCachingCloud EngineeringDistributed SystemsHigh-Throughput SystemsJavaMicroservicesPythonStorage Layers
2 Days AgoSaved
Remote
San Antonio, TX
98K-132K Annually
Senior level
98K-132K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Design, develop, and maintain ServiceNow solutions including integrations, MID Server setup, SAM Pro configuration, Service Catalog and portal items, CMDB alignment, and automation using Flow Designer and APIs. Collaborate with stakeholders, estimate work, write and execute tests, support UAT, and keep the platform aligned with SDLC and ITIL best practices.
Top Skills: DiscoveryEmployee CenterFlow DesignerGlide ApiIntegrationhubJavaScriptMid ServerRestService CatalogService PortalServicenowServicenow Sam ProSoapWeb Services
Reposted 2 Days AgoSaved
Remote
San Antonio, TX
125K-175K Annually
Senior level
125K-175K Annually
Senior level
Insurance
The Director of IT Applications leads the delivery of enterprise applications, ensuring that business systems effectively support operations across Finance, Sales, Marketing, HR, and more while driving automation and system improvements.
Top Skills: ConfluenceJIRAOracle NetsuiteSalesforceServicenow
Reposted 2 Days AgoSaved
Remote
San Antonio, TX
190K-215K Annually
Senior level
190K-215K Annually
Senior level
Healthtech
Lead global IT business enablement for Manufacturing and Quality, forging partnerships, driving innovation, and ensuring operational excellence through technology.
Top Skills: Advanced AnalyticsAutomationDigital TechnologiesErpLimsManufacturing Execution Systems
Reposted 2 Days AgoSaved
Remote
San Antonio, TX
161K-350K Annually
Senior level
161K-350K Annually
Senior level
AdTech • Digital Media • Information Technology • Other
The role involves designing and developing enterprise-grade software solutions, integrating AI tools, collaborating with teams, and maintaining documentation while enhancing productivity for Yahoo personnel.
Top Skills: AWSDockerGCPJavaKubernetesPython
3 Days AgoSaved
Remote
San Antonio, TX
73K-99K Annually
Senior level
73K-99K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Partner with stakeholders to gather and analyze requirements, improve Warehouse and Inventory systems, author and execute test plans/scripts, validate APIs and data via SQL and Kafka, support Agile delivery using VersionOne/ServiceNow, and coordinate cross-functional teams to drive system optimization and process improvements.
Top Skills: Agile ScrumApache KafkaApi TestingDevsecopsExcelOracle FormsOracle ReportsOutlookPowerPointSdlcServicenowSQLVersiononeVisioWord
3 Days AgoSaved
Remote
San Antonio, TX
116K-208K Annually
Senior level
116K-208K Annually
Senior level
Big Data • Marketing Tech • Analytics
Lead a Service Desk team supporting external financial clients; manage daily support operations, escalations, SLAs, and client communications; partner with engineering on incidents and continuous improvement; provide hands-on technical leadership across monitoring, integration, and database tools.
Top Skills: AICSSDatadogHTMLJavaScriptLinuxMulesoftMySQLPHPSalesforceServicenowShell ScriptingSplunkSQLTableauXML
Reposted 3 Days AgoSaved
In-Office or Remote
San Antonio, TX
Senior level
Senior level
Cloud • Information Technology • Software
Lead and manage a remote US IT support team to deliver high-quality technical support. Oversee daily operations, SLAs, ticket triage, knowledge base, training, metrics reporting, and escalation for complex issues while coordinating cross-functional initiatives and adopting industry best practices to improve customer satisfaction.
Top Skills: ItilItsmMicrosoft (WindowsNetwork TroubleshootingOffice/Microsoft 365)Remote Support ToolsTicketing SystemsUnified CommunicationsVoip
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3 Days AgoSaved
Remote
San Antonio, TX
Senior level
Senior level
Artificial Intelligence • Computer Vision • Machine Learning • Software
Provide day-to-day IT support for a globally distributed AI company: triage help-desk tickets, provision and ship laptops, manage Google Workspace, enforce endpoint security and device compliance, run onboarding/offboarding, maintain SaaS seat/license management, support office networking/AV, write runbooks, and contribute to security, infrastructure, and automation projects as the first EMEA IT hire.
Top Skills: AWSBashCi/CdCli Admin ToolingDevice Trust ToolingDhcpDnsEndpoint SecurityGCPGoogle WorkspaceInfrastructure-As-CodeJavaScriptLanmacOSMdm PlatformsNotionPythonSlackWanZoom
3 Days AgoSaved
Remote
San Antonio, TX
81K-97K Annually
Senior level
81K-97K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Lead subcontract strategy for large federal captures: advise capture leadership, develop multi-tier subcontracting plans, conduct market/supplier research, manage proposal inputs and FAR/DFARS compliance, lead negotiations, identify and mitigate subcontract risks, leverage analytics/AI for supplier performance, brief senior leadership, mentor junior staff, and ensure accurate documentation in source-to-pay and proposal systems.
Top Skills: Artificial Intelligence ToolsContract Management SystemsMicrosoft Office SuiteSource-To-Pay Systems
3 Days AgoSaved
Remote
San Antonio, TX
113K-138K Annually
Senior level
113K-138K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Lead budgeting, forecasting, and financial analysis for IT, HR, and I&HS organizations. Build and maintain forecasting models using Oracle Cloud, SmartView, and advanced Excel. Support audit readiness (DCMA/DCAA), collaborate with department managers, and drive capital expenditure and depreciation analysis to ensure accurate financial planning and reporting.
Top Skills: ExcelOracle CloudPower BISmartviewTableau
3 Days AgoSaved
Remote
San Antonio, TX
Senior level
Senior level
Software
Serve as the primary US IT contact, providing first-line support, managing helpdesk tickets, configuring and imaging devices via Workspace ONE, handling onboarding/offboarding and device lifecycle, maintaining IT asset records, and coordinating office infrastructure with vendors to ensure secure, reliable workplace technology.
Top Skills: Endpoint SecurityGoogle WorkspaceMdmOktaWorkspace One
3 Days AgoSaved
Remote
San Antonio, TX
75K-94K Annually
Senior level
75K-94K Annually
Senior level
Cloud • Information Technology • Productivity • Security • Software
Provide production support and development for Oracle EBS R12 and Oracle Cloud ERP finance modules. Design, build, and maintain PL/SQL packages, reports, data models, and dashboards; perform root-cause analysis and testing; support integrations (SOA/ODI/WebMethods); manage patching and cloud updates; produce technical documentation and enforce development standards while collaborating with functional teams.
Top Skills: Bi PublisherJavaJavaScriptOracle Cloud ErpOracle Data Integrator (Odi)Oracle Ebs R12Oracle FormsOracle ReportsOracle Soa SuitePl/SqlPythonSQLSql LoaderUnix Shell ScriptingWeb AdiWebmethodsWorkflows
3 Days AgoSaved
Remote
San Antonio, TX
140K-150K Annually
Senior level
140K-150K Annually
Senior level
Cloud • Information Technology • Productivity • Security • Software
Lead design, implementation, and integration of large-scale DoD Zero Trust solutions. Create system blueprints across on-premise, cloud, and hybrid environments, implement ICAM, network access control, micro-segmentation, and ABAC, ensure alignment with DoD Zero Trust Roadmap, lead engineering teams, optimize performance, troubleshoot systems, and produce clear architecture documentation.
Top Skills: AbacAWSAzureC#CloudDod Zero TrustGCPHybrid-CloudIcamJavaMicro-SegmentationNetwork Access ControlOn-PremisePythonZero TrustZero Trust Network Architecture
3 Days AgoSaved
In-Office or Remote
San Antonio, TX
84K-114K Annually
Senior level
84K-114K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Design and guide secure, scalable enterprise and cloud architectures (DNS, Azure, AWS, on-prem). Lead cloud migrations, implement monitoring, integrate hybrid environments, present technical briefings, and mentor staff while ensuring security and performance for a mission-focused government client.
Top Skills: AWSAzureAzure Virtual DesktopCloud MigrationDisa StigsDnsInfobloxLinuxLoad BalancingMicrosoft 365Monitoring ToolsNetworkingOffice 365On-Premises InfrastructureRoutersSystem AdministrationSystems DesignVdiVMware
Reposted 3 Days AgoSaved
Remote
San Antonio, TX
68K-92K Annually
Senior level
68K-92K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Develop and execute strategic communications for internal and external audiences supporting CBP trade enforcement. Create and edit print and digital content, presentations, talking points, and outreach materials. Translate technical concepts for general audiences, manage multiple assignments, support senior leadership rapid-turn needs, and adhere to federal style and plain-language standards while collaborating with distributed teams and facilitating meetings across platforms.
Top Skills: MS OfficeMs TeamsSharepointWebex
Reposted 3 Days AgoSaved
In-Office or Remote
San Antonio, TX
Senior level
Senior level
Blockchain • Fintech • Software • Financial Services • Cryptocurrency
Lead IT support operations, ensuring high-quality technical support, vendor management, and IT processes for a remote workforce while improving contributor experience.
Top Skills: APIsDnsIt Administration ToolsSaas SolutionsVpns
Reposted 4 Days AgoSaved
Remote
San Antonio, TX
85K-99K Annually
Senior level
85K-99K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Translate business needs into clear technical requirements, user stories, and acceptance criteria. Support product backlog prioritization, roadmap maintenance, Agile ceremonies, release planning, stakeholder communication, and process improvements to ensure timely, high-quality delivery.
Top Skills: Ai/MlServicenowServicenow Itsm
4 Days AgoSaved
In-Office or Remote
San Antonio, TX
130K-167K Annually
Senior level
130K-167K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Serve as RF/spectrum SME to port EL-CID Desktop functionality to EL-CID Online, author JIRA stories, manage product backlog, support developers, test releases, provide production support, train users, and produce technical documentation and system diagrams.
Top Skills: .CidConfluenceDow StepstoneEl-Cid DesktopEl-Cid OnlineJIRAPowerPointSsrfXMLXsdXslt
4 Days AgoSaved
Remote
San Antonio, TX
94K-160K Annually
Senior level
94K-160K Annually
Senior level
Healthtech • Pharmaceutical
Serve as a senior IT business/systems analyst bridging IT and clinical business units: gather and translate data and system requirements, document processes and high-level technical designs, support integrations and data quality, define user stories and acceptance criteria, coach junior analysts, lead prototyping, and drive implementations using Agile practices.
Top Skills: APIsExcelJIRALucidchartMS OfficeRelational DatabasesSQLVisio
4 Days AgoSaved
Remote
San Antonio, TX
Senior level
Senior level
Biotech • Pharmaceutical
Senior IT leader partnering with Commercial leadership to define and deliver pharma commercial technology strategy, oversee Veeva and digital platforms, lead product launch technology readiness, manage vendors/agencies, ensure compliance and governance, and lead IT teams to deliver scalable, secure commercial applications and digital experiences.
Top Skills: Accessibility StandardsAgile/ScrumAnalytics/Tagging PlatformsBusiness IntelligenceConsent ManagementCopay Program PlatformsCrm/Contact Center ToolsCustomer Data PlatformsCustomer Engagement ToolsData LakesDigital Asset ManagementHub IntegrationsItilMarketing AutomationMarketing Cloud PlatformsMaster Data ManagementPatient Services PlatformsPmpSeoVeeva AlignVeeva CrmVeeva Crm Events ManagementVeeva NetworkVeeva VaultVeeva Vault PromomatsWeb Content Management Systems
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