Top Remote Python Jobs in Washington, DC

Design, build, and optimize scalable real-time and batch data pipeline infrastructure. Develop backend features focused on reliability and performance, write well-tested code, review technical designs, and contribute to infrastructure across mobile, desktop, and server systems.

Design, build, and operate large-scale distributed web crawlers and data pipelines. Handle anti-bot systems and dynamic/JS-heavy sites, perform cleaning, deduplication, filtering, and normalization, and maintain datasets for model training while optimizing for cost, latency, and reliability.

The Senior Site Reliability Engineer is responsible for maintaining Wikimedia's infrastructure, improving reliability, automating processes, and collaborating with teams. The role involves troubleshooting, managing deployments, and leading incident responses while working remotely.

Lead and grow a distributed senior engineering team as a player-coach, delivering shared SaaS platform services and core AI capabilities. Drive cloud-native architecture, model integration, reliability, FedRAMP compliance, AI-first engineering practices, and partner closely with Product, Security, and Platform Engineering to define roadmaps and technical standards.

Develop, maintain, and automate Twilio's Compute cloud infrastructure including scalable cloud-native environments, VM orchestration, hardened AMIs, ASG/EC2 management, container images, and OS libraries. Collaborate with architects and engineers, produce IaC-compliant implementations, author documentation and runbooks, participate in on-call rotation, and support legacy and new platform components using automation and best practices.

Design, implement, and manage scalable cloud infrastructure (AWS/Azure/GCP); build and maintain CI/CD pipelines; automate provisioning with Terraform/Ansible; run containerized workloads with Docker and Kubernetes; implement monitoring and alerting (Prometheus, Grafana, ELK); enforce cloud security best practices; collaborate with development teams to optimize deployment, reliability, and performance.

Design, deploy, and manage scalable cloud infrastructure and CI/CD pipelines. Automate provisioning and configuration with IaC, manage containerized workloads with Docker and Kubernetes, implement monitoring and security best practices, and collaborate with developers to optimize application delivery and reliability.

Lead end-user facing engineering squads (about half the team), grow engineering capacity, and provide hands-on technical leadership. Drive distributed computing, cloud (AWS/Azure), CI/CD, Agile/Scrumban, mentoring, conflict resolution, and product delivery for a remote-first, time-zone-compatible global team. Travel periodically for face-to-face team interactions.

Owner of enterprise systems and automations: build and maintain Airtable bases and n8n integrations, write scripts and API/webhook integrations, administer NetSuite, monitor Snowflake pipelines, provide high-touch technical support, and document runbooks.

Design, develop, deploy, monitor, and support APIs and system integrations (Salesforce, REST, third-party). Work directly with clients to gather requirements, troubleshoot and optimize integrations, operate solutions in AWS, collaborate with teams, and mentor junior developers.

Build and ship full‑stack features for transportation management and other client products. Design and implement APIs and UIs, collaborate with product and design, own delivery, write modular testable code, troubleshoot and iterate quickly, and mentor peers.

Build, ship, and maintain production-quality web and mobile products. Contribute across product, design, and engineering, own delivery, write modular testable code, and mentor teammates while iterating quickly to deliver business value.

Develop and maintain Python applications focusing on iterators/generators/streams, concurrency (multithreading, non-blocking I/O), and high-precision numeric handling. Work with JSON/XML, REST and SOAP APIs, ACID-compliant databases, message brokers/queues, and produce clean, SOLID code. Unit and integration testing experience is beneficial.

Remote entry-level DevOps role responsible for deploying and managing containerized Python and JavaScript applications on cloud managed services (AWS/Azure/GCP). Implement CI/CD pipelines, container orchestration (Kubernetes/EKS/AKS/GKE), deploy web and microservice applications, node/django apps, and managed databases. Opportunity to work on data and ML infrastructure and scale deployments.

Build and maintain backend APIs and microservices using Django REST Framework and Django 3.0. Implement serialization, models, views, routers, authentication/authorization, and complex RESTful endpoints. Work with relational and NoSQL databases, complex SQL queries, nested JSON and XML, and ensure API security and scalability. Collaborate with data engineering on data and ML pipelines. Immediate joiners; remote, individual-contributor role in a startup-like environment.

Develop and maintain high-volume Kafka data ingestion pipelines in Python using Producer/Consumer APIs and Kafka Connect (Debezium/JDBC). Configure topics, brokers, schema registry, converters, and connectors; implement CDC, custom producer/consumer logic and transformations; optimize broker/producer/consumer/connect/stream settings; deploy multiple source/sink connectors to production and integrate Kafka with messaging systems like RabbitMQ, Redis, and AWS SQS.

Hands-on DevOps role focused on containerization and cloud deployments: build and deploy Docker images across VMs, container services, and Kubernetes; implement CI/CD pipelines; manage identity services and APIs; deploy web apps and microservices on AWS/Azure/GCP; monitor container logging and manage managed databases. Work as an individual contributor on production platforms.

Design, implement, and manage secure, highly available RHEL servers and Azure-based cloud solutions. Automate deployments with scripting, support Docker/Kubernetes pipelines, document systems, and adapt to new Azure resources to enhance capabilities for developer groups and military customers.

Lead architecture and development of secure, compliant financial systems (payments, billing, ledgers). Drive bank and processor integrations, ensure transaction integrity and observability, lead incident response, mentor senior engineers, and evaluate payment and AI technologies to improve customer and operational outcomes.

Build and operate internal APIs and delivery systems for Data Science solutions. Implement deployment, security, auth, and observability; support integrations; runbooks and documentation; participate in on-call rotations, incident response, and post-incident improvements; provide code reviews and mentorship; design solutions on cloud, Kubernetes, and LLM-enabled infrastructure.

As an Engineer at Archer, you will work on advanced aerospace programs, focusing on survivability technologies and Operations Analysis, leading cross-disciplinary teams.

The Staff Software Engineer will lead AI integration into software design, develop scalable systems, and mentor other engineers while improving best practices.

Lead and mentor SRE teams; partner with engineering, operations and product; apply statistical analysis and networking expertise to diagnose performance and reliability issues; define and implement data feeds; influence technical decisions and investments; build tooling to automate analytical workflows and increase platform reliability.

Lead Leap's engineering function: hire and scale a high-performing team, own the technical roadmap and architecture, build AI-native data and production ML systems (LLMs/agents), and deliver correct, auditable healthcare workflows for drug identity, causal attribution, and intervention automation.

Design, build, and own end-to-end features for AI-powered finance agents and agent orchestration. Implement integrations with accounting and payment platforms, create dashboards and reporting, ensure security and data integrity, make architectural choices, monitor production, and drive AI-assisted, agentic development workflows.