Top Remote Python Jobs in Washington, DC

Own the reliability, performance, resilience, observability, and security of AWS and Kubernetes infrastructure supporting products and AI/ML workloads. Define SLOs, lead incident response and root-cause analysis, build Terraform automation, optimize cloud costs, reduce operational toil, and establish deployment standards that help engineers ship reliably. Participate in on-call rotations and maintain HIPAA-compliant infrastructure.

Design, build, and operate backend services for Bestow’s insurance platform using Python, Go, Java, and PostgreSQL. Collaborate on technical decisions, integrations, carrier onboarding, and scalable platform capabilities. Mentor engineers through reviews and pairing, improve production reliability and observability, participate in on-call support, and communicate technical decisions in a remote-first environment. Use agentic AI coding tools daily and help establish effective AI-assisted development practices.

Administer hybrid Windows Server infrastructure across colocation, on-premises, Azure, and GCP environments. Manage virtual machines, cloud resources, patching, upgrades, backups, monitoring, alerts, incident response, vulnerability remediation, and root cause analysis. Develop automation using PowerShell, Python, Ansible, and infrastructure-as-code tools for provisioning, remediation, and self-healing workflows. Maintain documentation and runbooks while collaborating with engineering, IT support, security, and operations teams.

Owns delivery of backend money movement and card ledger systems, leading engineers through complex problems and ambiguity. Collaborates with product, design, analytics, and engineering stakeholders; defines scalable technical solutions; supports system availability, monitoring, on-call operations, code quality, and engineering standards. The role also includes mentoring and developing team talent while building highly available distributed systems for Affirm’s financial products.

Define the technical vision and multi-quarter strategy for Coinbase’s FinHub financial infrastructure. Architect scalable ledger and money-movement primitives across fiat and crypto, ensuring double-entry accounting, idempotency, reconciliation, auditability, reliability, and safe failure recovery. Lead complex cross-team architectural initiatives, collaborate with finance, risk, compliance, and operations stakeholders, and mentor senior engineers while improving system design and operational excellence.

Leads more than 10 engineers across Agent Tools, Agent Observability, and Runner Execution. Responsibilities include hiring, coaching, prioritization, technical design, AI tool standards, safe agent execution, sandboxing, observability, and cross-functional partnership across GitLab’s AI organization.

Define architecture and metrics for autonomous driving evaluation, lead cross-functional integration across autonomy and simulation teams, develop statistical and machine learning methods, analyze large-scale time-series data, manage evaluation KPIs and release gates, and communicate safety and readiness insights through dashboards and stakeholder presentations.

Leads the data infrastructure platform team responsible for production services supporting batch, streaming, analytics, and machine learning workloads. Oversees people leadership, platform strategy, reliability, security, scalability, cost efficiency, incident response, roadmap execution, and cross-functional collaboration. Builds self-service developer experiences, standardized CI/CD, observability, infrastructure automation, and service ownership practices across Airflow, Flink, Spark, Kafka, Snowflake, Iceberg, AWS, and ML platforms.

Build and operate AWS GovCloud data infrastructure across development, preproduction, and production environments. Establish PostgreSQL platforms, infrastructure-as-code with Chef, BI infrastructure, identity integrations, monitoring, observability, CI/CD, and disaster recovery. Support data pipelines, troubleshoot incidents, optimize databases, and ensure FedRAMP and FISMA compliance. Collaborate with security, compliance, DevOps, and data engineering teams while delivering greenfield infrastructure from architecture through production.

Design, develop, and field high-performance Ground Control Station and C2 software using C++/Qt/QML and QGroundControl. Lead architecture and technical direction, mentor engineers, define APIs/ICDs, debug integration/latency issues, support field tests, implement post-mission debrief tools, and ensure interoperability with C2 standards.

Lead systems engineering for Hivemind-based autonomy products: define and manage requirements, develop system architectures and trade studies, coordinate hardware/software interfaces, support integration/verification/validation and testing, and identify and mitigate technical risks across the system lifecycle.

Lead design and prototyping of generative AI experiences for autonomy development; drive UX for Hivemind products; perform user research, collaborate with CTO and product leads, and deliver reference implementations and integrations across full-stack web and edge systems.

Design and implement full‑stack, low‑latency web-based Ground Control Station and C2 systems (map-centric UIs, real-time telemetry, video streaming), lead architecture and APIs, mentor engineers, support field tests and mission deployments, and ensure interoperability with C2 standards.

As a Senior Site Reliability Engineer, you'll design and build complex systems, support Atlas platform operations, automate processes, and ensure high availability of services.

Support and maintain complex applications and infrastructure for a government customer: monitor and triage events, troubleshoot Linux/Windows servers, deploy and integrate software (AWS, CloudFormation, RDS), use Salt for configuration management, work with databases (Oracle, MongoDB, PostgreSQL, MySQL), write SOPs, manage security groups, and support after-hours deployments. Requires strong communication and collaboration with developers and vendors.

Develop and implement embedded software and systems for aerospace devices. Responsibilities include coding, testing, troubleshooting, software quality assurance, system efficiency and stability analysis, and I/O performance optimization. Interns work with hardware and embedded technologies while receiving mentorship and professional development. The role is available at multiple U.S. locations and includes relocation benefits and short-term housing for eligible interns.

Develop and implement embedded software and devices for aerospace systems. Responsibilities include analyzing system efficiency and stability, optimizing I/O performance, supporting software quality assurance, and coding, testing, and troubleshooting system software. The intern will work with embedded hardware and software technologies while receiving hands-on experience, mentorship, relocation benefits, and short-term housing when eligible.

Lead the architecture and delivery of large-scale React and React Native applications across web and mobile. Establish frontend standards for performance, accessibility, reliability, and maintainability; build shared component libraries and design systems; resolve complex frontend and cross-stack issues; partner with product, design, and backend teams; and mentor engineers while shaping technical strategy across multiple product areas.

Lead architecture and delivery of complex web and mobile product initiatives. Build React and React Native applications, scalable components, APIs, data models, and shared libraries. Establish engineering standards, improve testing, performance, security, and reliability, and optimize database queries. Mentor engineers, guide technical decisions, and partner with leadership and stakeholders to shape the product roadmap. This is a fully remote role supporting veterinary clinic operations and supply-chain workflows.

Build and maintain features across Vetcove’s web, backend, and mobile platforms. Responsibilities include developing React and React Native applications, creating reusable components, improving test coverage, designing performant and secure data models, optimizing database queries, writing API endpoints, and collaborating with engineering, product, and company leadership in a fully remote environment.

Own and lead the technical direction of a major codebase section while designing, building, testing, documenting, and maintaining secure, scalable API-based decisioning products. Partner with product, engineering, and security teams on agile delivery, troubleshoot production issues, meet SLA requirements, and participate in an on-call rotation.

Designs and maintains automated test frameworks and exploratory suites for products, APIs, SDKs, AI models, and data platforms. Develops functional, integration, end-to-end, regression, API, browser, load, and reliability tests; creates datasets, evaluation pipelines, dashboards, and CI/CD release gates. Partners across Engineering, Research, Product, Data, and Infrastructure to validate model behavior, data quality, performance, and production readiness. Documents reproducible defects, supports triage, and communicates risks.

Own the design, development, and automation of Coinbase’s routing infrastructure connecting services to Kubernetes backends. Build scalable capabilities using Envoy, Istio, Ambient Mesh, and SPIFFE; improve routing latency, reliability, and performance; enhance developer tooling with responsible AI; and collaborate with security, reliability, and observability teams to resolve complex distributed-systems issues.

Lead a hands-on software engineering effort for Zeta’s real-time events pipeline. Design, build, deploy, and operate high-volume event ingestion, processing, and delivery systems. Own architecture, reliability, observability, performance, cost, data quality, and on-call improvements. Collaborate with Product, Data, and downstream platform teams, define stable interfaces and SLAs, evaluate technologies, lead production launches, and mentor engineers through design and code reviews.

Build and maintain NetBox Enterprise, an on-premises product suite. Responsibilities include architecting Kubernetes-based high-availability solutions, extending Kubernetes operators, developing lifecycle management tools, building CI/CD pipelines, managing releases, writing Rust and Python, supporting integration testing, documenting deployment practices, and resolving customer deployment and operational issues.