Top Remote Python Jobs in San Diego, CA

Design and build a scalable, responsive UI; lead frontend architecture and optimization; apply UI/UX best practices; integrate with backend APIs; ensure high web performance and deploy user-facing features.

The Senior Database Administrator will manage database operations, support cloud migration, ensure reliability in Azure environments, and collaborate with teams for database and application integration.

Design and build backend services for ClickHouse Cloud, extend functionalities for Postgres, and contribute to automation and operational excellence, ensuring performance and reliability.

As a Software & Data Engineer, you will design data pipelines, deploy AI tools, build data warehouses, and integrate systems for clients, ensuring data quality and performance.

The SDET Automation Engineer will develop and execute automated test scripts, enhance test suites, and collaborate with teams to ensure quality in web applications.

You will manage AWS infrastructure, automate deployments, debug application issues, and improve the operational health of Metabase Cloud.

As a Software Engineer, you'll design solutions for employer benefits, build software using modern technologies, and engage in continuous improvement and mentorship within the team.

Design, build, and maintain automated and manual tests and frameworks to ensure software quality. Collaborate with cross-functional teams to define test strategies, execute test suites in CI/CD, report defects, and improve automation coverage and processes. Support functional, regression, performance, usability, and security testing and communicate quality metrics to stakeholders.

Build customer-facing observability features: backend systems that transform raw observability data (New Relic, Grafana, Cloudflare, OpenTelemetry) into actionable product insights. Work primarily in Go with Python and SQL for data, and collaborate with product and design on Portfolio Insights, OpenTelemetry exploration, and product analytics surfaced in the UI.

Lead design, implementation, and operation of Signifyd's GCP/Kubernetes cloud platform. Architect scalable, secure infrastructure, embed AI-driven automation, own SLOs and incident response, improve developer experience via CI/CD/GitOps tooling, mentor engineers, manage cloud capacity/FinOps, and build observability and security into the platform.

The Software Engineer II will develop Django-based websites using Python and work with large data sets while collaborating with teams to deliver high-quality work in a remote environment.

Own and improve AWS cloud environment, network connectivity, and internal IT operations. Implement IaC for client onboarding, harden network/security, monitor and remediate vulnerabilities, maintain HIPAA-compliant configurations, manage device enrollment/MDM and IAM, optimize cloud costs, automate infrastructure processes, and support engineering as the go-to cloud resource.

Lead developer experience strategy and build platform tooling to accelerate engineering productivity. Design and optimize CI/CD pipelines, lifecycle automation, golden paths, and developer tools; reduce fragmentation, improve reliability and observability across multi-cloud environments, and evaluate AI-assisted tooling and coding agents to improve build, test, deployment, and operations workflows.

Design and optimize AWS-based data architectures focusing on healthcare and enterprise analytics, bridging operational and analytical needs while incorporating AI tools and DataOps practices.

Design, build, and maintain automation workflows and integrations across Microsoft 365, Google Workspace, and other SaaS platforms using PowerShell, Python, Azure services, and APIs. Automate user management, notifications, data sync, and access workflows while implementing secure logging, monitoring, error handling, and documentation. Collaborate with IT, Security, and business teams to optimize processes and reduce manual work.

Design, deploy, and operate secure, scalable Azure environments. Build and maintain infrastructure as code, CI/CD pipelines, and networking/access controls. Ensure platform reliability, monitoring, governance, cost optimization, and disaster recovery while collaborating with engineering teams and maintaining documentation and standards.

Engineer and maintain cloud-based application deployments as as-a-code (AaC) using CI/CD pipelines. Configure, deploy, and troubleshoot tools like TeamWork Cloud, Cameo, and Cassandra; integrate applications with workflow/ticketing systems; develop integration interfaces (Python, PowerShell, Groovy); implement IDAM solutions; build test plans and documentation; and use DevOps tooling (Ansible, Terraform, Jenkins, GitLab). Active TS/SCI with CI poly and DoDD 8140 Security+ CE required.

Lead frontend architecture and product development for member-facing web and mobile apps. Build high-performance, accessible React/React Native UIs, own end-to-end features including APIs and backend services, mentor engineers, drive design system and frontend standards, and collaborate with Product, Design, Clinical, and Data teams to deliver scalable, user-centered health experiences.

Lead design and delivery of customer-facing data product applications, building full-stack experiences (frontend, backend, APIs) using TypeScript, React, Node.js, and Python. Partner with Product and data teams to convert analytics and prototypes into production-grade workflows, establish software engineering best practices, mentor engineers, and prioritize customer value through testing, observability, and operational ownership.

Manage a team developing accelerated image and data compression libraries. Define project goals, roadmap, and scope; ensure execution and delivery; elevate engineering practices; collaborate with internal and external customers and the open-source community while fostering an inclusive, innovative environment.

Design, implement, and maintain GCP-based infrastructure using IaC. Own cloud networking, compute, CI/CD, observability, security controls, backups, and containerized deployments. Support development and data science teams, troubleshoot issues, create documentation and runbooks, and ensure compliance in a regulated research environment.

Work with the development team to build and debug web applications: write Python backend code, create responsive HTML/CSS/JavaScript frontends, integrate frontend and backend, participate in code reviews and testing, learn frameworks and document progress.

Build and maintain core backend services and frontend interfaces for a music metadata and royalties platform. Own features end-to-end, collaborate with founders and designers, optimize for performance, security, and scalability, and integrate modern AI and infra tools.

Design, build, and maintain performant web applications in an agile, TDD-driven environment. Lead technical decisions, collaborate with product and design, deliver high-quality code, participate in on-call rotation, and ensure system reliability and availability.

Build and scale a fintech platform across accounting, tax, and banking. Own feature lifecycle from design to deployment, write backend and frontend code, improve infrastructure and reliability, and collaborate with product and design to deliver customer-focused features.