Top Remote Staff Software Engineer Jobs

22 Days AgoSaved
In-Office or Remote
San Francisco, CA, USA
177K-271K Annually
Senior level
177K-271K Annually
Senior level
Healthtech • Biotech • Pharmaceutical
Lead design and build of an end-to-end SaaS product that wraps Lilly's AI/ML and LLM models for biotech customers. Architect frontend, backend, data and integrations, implement federated learning, establish engineering practices (testing, releases, on-call), mentor hires, recruit, and coordinate with internal platform, security, and customer stakeholders.
Top Skills: Ai/MlAPIsClaude CodeCloud DeploymentCursorFederated LearningLlmSaaS
22 Days AgoSaved
In-Office or Remote
2 Locations
150K-180K Annually
Senior level
150K-180K Annually
Senior level
Analytics
Develop, design, and maintain production software for autonomous mission management of a satellite constellation. Contribute to architecture, implement scalable algorithms in Python and Go, support production operations, on-call rotations, launches, and cross-team integration for automated constellation operations.
Top Skills: GoPython
22 Days AgoSaved
In-Office or Remote
3 Locations
Expert/Leader
Expert/Leader
Information Technology • Consulting
Lead design and implementation of scalable, secure health-data systems. Code and mentor engineering teams, drive cross-functional projects end-to-end, solve complex technical problems, and advance data integration and AI-enabled services.
Top Skills: AWSDockerGCPPostgresPythonReactReact Native
Reposted 22 Days AgoSaved
Remote
USA
Senior level
Senior level
Pharmaceutical
Lead design, development, and maintenance of SmithRx frontend features using JavaScript and React while ensuring high-quality code and scalability. Collaborate with product teams and mentor junior engineers.
Top Skills: Ci/CdCloud ServicesCSSCypressDockerGraphQLHTMLJavaScriptReactSelenium
22 Days AgoSaved
Remote
US
Senior level
Senior level
Software
Lead design, development, and maintenance of scalable backend services for Payouts. Drive architecture, ensure performance and reliability, mentor engineers, enforce engineering best practices, and collaborate with product and support teams to deliver customer-facing REST APIs.
Top Skills: AchCi/CdDockerGit-FlowJavaJunitKubernetesMockitoMySQLOraclePayment RailsPostgresRestSonarqubeSpring Boot
22 Days AgoSaved
Remote
United States
205K-231K Annually
Expert/Leader
205K-231K Annually
Expert/Leader
Cloud • Security • Software
Own and design high-impact components of Chainguard's container image platform. Build and improve image build systems, tooling, and services at scale. Drive technical direction, participate in roadmap planning, collaborate cross-functionally, and mentor engineers to raise engineering quality.
Top Skills: CompilersContainer RegistriesDockerGoKubernetesMakefilesTerraformToolchains
Reposted 22 Days AgoSaved
Remote
United States
180K-200K Annually
Senior level
180K-200K Annually
Senior level
Artificial Intelligence • Software
Design high-performance C++ libraries for automated PCB design challenges, mentoring peers and shaping technical direction while collaborating with experts in various fields.
Top Skills: C++CudaPython
Reposted 22 Days AgoSaved
Remote
USA
Senior level
Senior level
Artificial Intelligence • Fintech • Software • Financial Services
Design and build AI-powered backend services, optimizing performance and scalability while collaborating with cross-functional teams to integrate generative AI models.
Top Skills: AWSClickhouseDockerGitGradleJavaJenkinsKafkaKubernetesMavenPython
Reposted 22 Days AgoSaved
Remote
USA
Senior level
Senior level
Pharmaceutical
As a Staff Software Engineer, you will develop backend architecture, collaborate with stakeholders, mentor juniors, and ensure software quality while leveraging various technologies and AWS platforms.
Top Skills: AWSDockerGoGraphQLJavaScriptKubernetesNode.jsPostgresSQLTypescript
Reposted 22 Days AgoSaved
Remote
USA
150K-180K Annually
Senior level
150K-180K Annually
Senior level
PropTech
As a Staff Software Engineer, you will significantly enhance platform development and experimentation, focusing on AI integration and efficient software workflows. You'll manage end-to-end processes, develop core infrastructure, and employ AI coding agents to refine engineering practices, ultimately improving velocity and output quality.
Top Skills: Ai Coding AgentsCi/CdCloud PlatformsSoftware Architecture
Reposted 22 Days AgoSaved
Remote
United States
Expert/Leader
Expert/Leader
Financial Services
As a Staff Software Engineer, you'll architect scalable technical solutions, define standards, mentor engineers, and lead initiatives for reliability and security across multiple systems.
Top Skills: Api DesignCloudObservabilitySecurity Practices
Reposted 22 Days AgoSaved
Remote
USA
190K-220K Annually
Senior level
190K-220K Annually
Senior level
Fintech • Financial Services
The Staff Software Engineer will lead design and development of cryptocurrency platforms, provide technical mentorship, and drive system reliability, while staying current on blockchain trends.
Top Skills: AWSBlockchainC#DockerMasstransitNservicebusPostgresRabbitMQSQLSQL Server
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Reposted 22 Days AgoSaved
Remote
United States
175K-225K Annually
Senior level
175K-225K Annually
Senior level
Artificial Intelligence • Information Technology • Consulting
Design, build, and operate reliable backend systems while mentoring engineers, participating in design discussions, and improving system performance.
Top Skills: GoKubernetesLinuxMongoDBNoSQLPostgresPythonSQL
Reposted 22 Days AgoSaved
In-Office or Remote
Canada, KS, USA
192K-230K Annually
Senior level
192K-230K Annually
Senior level
Artificial Intelligence • Big Data • Information Technology • Professional Services • Software
As a Senior Software Engineer, you will build and maintain secure infrastructure for GraphQL, debug escalations, collaborate with teams, mentor, and improve the platform's performance.
Top Skills: Rust
Reposted 22 Days AgoSaved
Remote
US
126K-215K Annually
Senior level
126K-215K Annually
Senior level
Software • Financial Services
The Staff Software Engineer shapes AI platform strategy, leads architectural decisions, mentors junior engineers, and ensures compliance for AI capabilities in a financial context.
Top Skills: AWSDatadogDjangoDockerFastapiGrafanaKubernetesPrometheusPythonReactRestful ApiTerraformTypescriptVector Databases
23 Days AgoSaved
Remote
2 Locations
152K-281K Annually
Senior level
152K-281K Annually
Senior level
Kids + Family • Mobile
Lead architecture and implementation of high-throughput, low-latency AdServer and Exchange services. Design scalable, resilient distributed systems, integrate demand/supply partners, improve RTB/auction capabilities, advance observability and automation (including AI-driven testing/IaC), and mentor engineers to increase platform reliability and revenue growth.
Top Skills: Ad ExchangeAdserverAWSClaude CodeCloud-NativeCursorGithub CopilotInfrastructure As Code (Iac)JavaReal-Time Bidding (Rtb)
23 Days AgoSaved
In-Office or Remote
Overland Park, KS, USA
Senior level
Senior level
Healthtech • Professional Services • Software
Design, build, and operate scalable multi-cloud platform services and tooling. Manage Kubernetes clusters and GitOps/CI-CD tooling (ArgoCD, Spacelift, GitHub). Collaborate with product teams, lead architecture and code reviews, resolve high-priority production incidents, and mentor engineers while automating operational toil.
Top Skills: Ai Tools And PlatformsArgocdAutomated Unit/Integration TestingAWSAzureCi/CdGCPGitGitopsKubernetesSpacelift
Reposted 2 Hours AgoSaved
In-Office or Remote
7 Locations
Senior level
Senior level
Artificial Intelligence • Hardware • Automation • Manufacturing
Design and lead frontend architecture and development for scalable, secure web UIs that integrate with embedded systems and cloud platforms. Build device provisioning, telemetry visualization, and remote management interfaces; optimize performance and accessibility; mentor engineers; collaborate across backend, hardware, and systems teams to deliver end-to-end solutions.
Top Skills: AngularAWSAzureBabelCSS3D3.JsEmberGCPGitHTML5JavaScriptReactReact RouterReduxRestful ApisTypescriptVueWebpack
23 Days AgoSaved
Remote or Hybrid
United States
205K-265K Annually
Senior level
205K-265K Annually
Senior level
AdTech • Digital Media • eCommerce • Marketing Tech • Mobile • Software
Define and drive full-stack architecture and technical vision across teams, write high-quality production code, lead zero-to-one projects, productionize ML systems, own reliability and SLOs, mentor senior engineers, and align engineering roadmaps with product and company strategy.
Top Skills: AWSDockerGoJavaScriptNode.jsPythonReactRelational DatabasesTypescript
Reposted 23 Days AgoSaved
Remote
United States
Mid level
Mid level
Software • Cybersecurity
As a Staff Software Engineer at Socket, you will build the product, enhance the team culture, and establish foundational frameworks while contributing to the development of the web application and APIs.
Top Skills: ElasticsearchGraphQLJavaScriptNode.jsPostgresReactTypescript
Reposted 23 Days AgoSaved
In-Office or Remote
2 Locations
242K-389K Annually
Senior level
242K-389K Annually
Senior level
Artificial Intelligence • Machine Learning • Robotics • Software • Transportation • Design • Manufacturing
Lead ML Performance Optimization for autonomous driving, collaborating across teams, implementing optimization techniques, and mentoring engineers for career growth.
Top Skills: C++PythonPyTorchRay ServeTensorrt
Reposted 23 Days AgoSaved
Remote
United States
220K-270K Annually
Senior level
220K-270K Annually
Senior level
Artificial Intelligence • Healthtech • Software
The Staff Machine Learning Engineer will develop and maintain MLOps tools, optimize model performance, and collaborate on ML system architecture with a focus on enhancing developer experience.
Top Skills: AirflowAWSDbtDockerKubernetesMlflowPythonPyTorchSnowflakeSQLTensorFlowTerraform
Reposted 23 Days AgoSaved
Remote or Hybrid
3 Locations
148K-260K Annually
Senior level
148K-260K Annually
Senior level
Transportation
Build scalable ML data pipelines for Waabi's autonomous driving platform. Design, optimize, and manage datasets and training processes while collaborating with scientists and engineers.
Top Skills: Apache AirflowApache BeamApache HadoopSparkAws Step FunctionsGoogle Cloud DataflowJaxPythonPyTorchTensorFlow
Reposted 23 Days AgoSaved
Remote or Hybrid
3 Locations
159K-268K Annually
Mid level
159K-268K Annually
Mid level
Transportation
Contribute to the development of Waabi World, improve simulation scalability, and design orchestration software for autonomous vehicle simulations.
Top Skills: C++PythonRust
Reposted 23 Days AgoSaved
Remote
United States
164K-205K Annually
Expert/Leader
164K-205K Annually
Expert/Leader
Marketing Tech
The Staff Software Engineer will lead the architecture and development of a real-time content platform, working on both backend and frontend systems while mentoring team members and collaborating with product and design teams.
Top Skills: AWSAzureCloudflareContainerizationGCPGraphQLRestWebhooks
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