Top IT Jobs in San Luis Obispo, CA

Remote IT Manager responsible for analyzing, upgrading, and administering IT systems (networks, servers, email, backups), evaluating vendors and technologies, managing projects, tracking inventory, training staff, and providing technical support to improve operational efficiency.

The Senior IT Systems Administrator oversees the administration, security, and optimization of financial systems, ensuring reliability and compliance while leading system enhancements and integrations.

The Senior Clinical Trials IT Business Analyst bridges Clinical Development and IT, optimizing clinical trial technologies and managing system implementations, validations, and stakeholder engagement.

The Lead IT Engineer will oversee projects, ensuring effective use of resources and alignment with organizational identity and rewards.

Lead design, implementation, and optimization of ServiceNow ITOM (Discovery, Service Mapping, Event Management) and CMDB governance. Configure MID Servers, patterns, probes, and integrations; manage cloud discovery across AWS/Azure/GCP; build automations with Flow Designer and APIs; perform performance and root-cause analysis; liaise with vendors; produce technical strategy, capacity planning, and translate technical solutions for business stakeholders.

Provide hands-on IT support for manufacturing and corporate environments: troubleshoot production/test stations, maintain Windows and Linux systems, manage virtualization (VMware/Hyper-V/Azure), networks, monitoring, backups, and automation (PowerShell/Bash). Create documentation and training, work with DB/network/process-control teams, and improve processes through data-driven analysis and quality/safety practices.

Provide 1st–3rd line IT support for US regional employees and executives, manage ServiceNow tickets, troubleshoot Windows, macOS, mobile devices, AV/conference rooms, printers and networks, administer Active Directory, liaise with escalation teams and third parties, and provide on-site support including travel and occasional out-of-hours coverage.

The IT Operations Director leads Service Desk and Infrastructure teams, overseeing IT operations lifecycle, managing metrics, enforcing security, and enhancing service quality through automation and ITIL processes.

The IT Program Manager will oversee technology support for training courses, manage complex systems, ensure data security, and provide technical leadership to meet mission objectives.

Manage full project lifecycle for IT Operations and Services, including enterprise applications, security, network/systems infrastructure, and process improvements. Create plans, governance, change management, vendor onboarding, KPIs, roadmaps, and transition projects to operations while communicating status and driving cross-team collaboration.

Administer, maintain, and optimize enterprise time-series data historian platforms. Monitor system health, manage data ingestion and interfaces, configure tags/compression/retention, troubleshoot gaps and latency, perform upgrades/backups, enforce data governance and security, support users and teams, and recommend performance and automation improvements.

Lead and manage Level 1-3 Service Desk analysts supporting external clients, oversee daily operations, escalations, SLAs, and reporting. Improve service management, automation, and first-call resolution; partner with Engineering and Incident/Problem/Change Management to resolve production issues. Provide hands-on technical leadership across Splunk, Datadog, MuleSoft, SQL, and ServiceNow while managing client communications and operational metrics.

Provide IT helpdesk support and device administration across Windows, macOS, and Linux. Manage MDM, SSO, enterprise SaaS, onboarding/offboarding, hardware deployment, asset inventory, endpoint security, and related procurement/shipping. Troubleshoot networks (LAN/WAN), create automation scripts, deliver staff training, participate in on-call rotations, and collaborate with HR and Security teams to maintain secure, scalable IT operations.

The internship offers hands-on training in Nutanix technologies, focusing on IT infrastructure and cloud services, with potential full-time roles thereafter.

Manage company devices, provisioning, lifecycle, and SaaS accounts; administer SharePoint and shared drives; implement IT security (MFA, endpoint controls); provide day-to-day support; coordinate vendors; develop IT policies, SOPs, and automation to scale internal IT operations.

The Senior IT Project Manager will lead client-facing IT infrastructure projects, manage timelines and expectations, and coordinate engineering teams while ensuring high-quality delivery of services.

The role involves leading and improving IT operations, focusing on proactive service organization, process design, and team development while managing IT projects and vendor relationships.

Provide technical systems support for IT environments, troubleshoot and resolve user/system issues, maintain and monitor systems, and ensure work is performed within required U.S. locations and citizenship constraints.

Lead technology strategy and operations for a commercializing biotech: define multi-year roadmap, deploy commercial and enterprise systems, ensure cybersecurity and GxP validation, manage infrastructure, data governance, vendors, and IT teams to support commercialization, regulatory readiness, and operational excellence.

Design, build, test, and maintain Android apps using Kotlin (and Java when needed). Collaborate with product, design, backend, and QA teams; implement responsive UIs, integrate REST APIs and third-party SDKs, optimize performance, support Play Store deployments, and follow SDLC standards.

Manage global accounting and financial planning IT projects and programs: lead cross-functional and vendor teams, prioritize requirements, create schedules, track risks and milestones, drive technical builds, integrations, testing, and delivery using Agile/Waterfall/hybrid methodologies.

Lead Manhattan Active WM solution design and multi-site rollout, migrate legacy WMS/TMS/WES/WCS, define processes and standards, validate warehouse hardware and automation, manage integrations, testing, cutover, go-live stabilization, documentation, and mentor internal teams.

The IT Specialist will install, configure, and maintain IT systems, troubleshoot issues, perform hardware upgrades, and optimize network performance.

Responsible for IT support and administration for Commercial systems. Partners with business owners to ensure system performance, compliance, and operational excellence across various business functions.

Contract IT System Administrator to manage and harden multi-cloud (AWS/Azure) infrastructure and Microsoft 365 identity/collaboration stack, support endpoints and managed IT/security SaaS platforms, automate routine tasks with scripting, maintain documentation and compliance posture for Department of War mission spaces, and serve as hands-on technical escalation for operational issues.