Top Senior Data Science Jobs in San Diego, CA

Reposted 29 Days AgoSaved
Remote
San Diego, CA
145K-180K Annually
Senior level
145K-180K Annually
Senior level
Healthtech • Telehealth
Senior individual contributor who drives product analytics, experimentation, and applied modeling. Owns growth and performance analyses, designs experiments with robust statistical evaluation, builds repeatable reporting, and partners with Product, Engineering, Operations, Clinical, and Finance to translate data into actionable product and operational decisions.
Top Skills: BigQueryPandasPythonRedshiftScikit-LearnSnowflakeSQLStatsmodels
Reposted 29 Days AgoSaved
In-Office or Remote
San Diego, CA
48K-170K Annually
Senior level
48K-170K Annually
Senior level
Agency • Information Technology
Build and scale production Generative AI applications: design multi-agent systems and LangGraph workflows, implement advanced RAG with vector DBs, integrate and fine-tune LLMs, deploy FastAPI async services in Docker, and optimize GenAI performance, cost, and monitoring.
Top Skills: Api SecurityAsync PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLlm QuantizationLocal Model DeploymentModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
Reposted 29 Days AgoSaved
In-Office or Remote
San Diego, CA
56K-196K Annually
Senior level
56K-196K Annually
Senior level
Agency • Information Technology
Build and scale production-ready generative AI applications: design multi-agent workflows, implement advanced RAG with vector DBs, integrate/swap LLMs, fine-tune models, and deploy scalable FastAPI/Docker services with monitoring and optimization for latency, cost, and reliability.
Top Skills: Async PythonCi/CdClaudeDockerFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm Quantization/HostingModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector Databases
Reposted 29 Days AgoSaved
In-Office or Remote
San Diego, CA
56K-196K Annually
Senior level
56K-196K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production-ready generative AI applications: architect multi-agent workflows, implement advanced RAG with vector DBs, integrate/swap LLMs, fine-tune models, and deliver scalable FastAPI-based services with monitoring, CI/CD, and containerized deployment.
Top Skills: Async PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
One Month AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Software • Consulting • Cybersecurity • Defense
Design, train, fine-tune, deploy, and monitor Large Language Models for government mission applications. Collaborate with cross-functional teams, ensure data preprocessing and model performance, present findings to stakeholders, and mentor junior data scientists.
Top Skills: BertGptLarge Language ModelsNlpPythonPyTorchTensorFlowTransformers
Reposted One Month AgoSaved
In-Office
San Diego, CA
180K-270K Annually
Senior level
180K-270K Annually
Senior level
Social Impact
Drive pricing and yield optimization at GoFundMe by applying economics, behavioral science, and machine learning. Lead experimentation, model decision-making, and translate insights into action, while ensuring high standards for modeling and collaboration with product teams.
Top Skills: AIEconometricsLlm (Large Language Model)Machine LearningPythonSQL
10 Days AgoSaved
In-Office or Remote
San Diego, CA
125K-145K Annually
Senior level
125K-145K Annually
Senior level
Edtech
Lead experimentation and decision science initiatives from problem definition through recommendations. Design and analyze A/B tests, quasi-experiments, matched-market tests, and causal inference studies. Apply advanced statistics, regression, predictive modeling, machine learning, and big-data analysis using Python, R, SQL, and PySpark. Partner with stakeholders, communicate actionable findings, build reproducible workflows, and mentor analysts and junior data scientists.
Top Skills: PysparkPythonRSQL
One Month AgoSaved
Remote
San Diego, CA
185K-231K Annually
Senior level
185K-231K Annually
Senior level
Artificial Intelligence • Software • Analytics • Business Intelligence
Lead and build Neural Earth's geospatial data science function: design and deploy Python-based geospatial models, architect production geospatial data pipelines, validate reproducible methods, translate scientific outputs into customer-ready products, and manage and mentor at least one direct report while advising customers and stakeholders.
Top Skills: CogGdalGeopandasGeoparquetGeotiffNetcdfPythonRasterioShapelyXarray
11 Days AgoSaved
Remote
San Diego, CA
100K-132K Annually
Senior level
100K-132K Annually
Senior level
Healthtech • Social Impact
Build, validate, deploy, monitor, and maintain predictive models and analytical reports. Translate findings for technical and non-technical stakeholders, promote data literacy, deliver training, collaborate on data infrastructure, apply advanced statistical and machine learning methods, and support analytical requests across mental health and crisis care programs.
Top Skills: Amazon RedshiftAmazon SagemakerAWSDeployment PipelinesModel RegistriesPandasPythonRScikit-LearnSnowflakeTidyverseVersion Control
Reposted One Month AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Logistics • Software
Senior individual contributor owning complex end-to-end ML problems for supply chain and consumer applications. Build and deploy predictive models (demand forecasting, delivery ETA, recommendations), embed with engineering teams, define MLOps standards, and advise leadership on data science strategy and investments.
Top Skills: Api EndpointsAWSAzureBigQueryDrift DetectionExperimentation FrameworksGCPGitGitMicroservicesModel VersioningPipeline OrchestrationPostgresPythonSQL
Reposted One Month AgoSaved
Remote
San Diego, CA
150K-195K Annually
Senior level
150K-195K Annually
Senior level
Software • Cryptocurrency • Web3
Partner with Marketing as the embedded data science lead to build marketing measurement, attribution, LTV/ROAS/CAC models, run experiments, analyze the full funnel, create forecasts and dashboards, and influence channel strategy and budget allocation.
Top Skills: Ad PlatformsAppsflyerGoogle AnalyticsLookerMmpPythonRSQLTableau
Reposted One Month AgoSaved
Remote
San Diego, CA
255K-298K Annually
Senior level
255K-298K Annually
Senior level
Consumer Web • Other • Social Media • Software
As the Staff Data Scientist, you will lead the data science function, driving strategy, mentoring peers, and shaping product direction through advanced analytics and experimentation.
Top Skills: PythonSQL
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Reposted One Month AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Big Data • Food • Mobile • Payments
Lead company-level measurement and causal strategy, define MAU×ARPU metrics and semantic mart, set scientific standards for experimentation and analysis, own strategic models (MMM, elasticity, forecasting), partner with engineering to productionize analytics, and raise org-wide scientific maturity through governance, templates, and upskilling.
Top Skills: DbtExperimentation PlatformsPythonSnowflakeSQL
11 Days AgoSaved
Remote
San Diego, CA
160K-200K Annually
Senior level
160K-200K Annually
Senior level
AdTech • Fintech • Marketing Tech
Build and deploy machine learning and experimentation systems for personalization, ranking, targeting, attribution, and causal measurement. Develop features and pipelines from transaction and behavioral data, design A/B tests, productionize models with engineering teams, and improve recommendation systems. Translate analytical results into business insights tied to conversion, retention, lift, and ROI while owning projects from problem framing through post-launch evaluation.
Top Skills: AirflowAPIsAWSDbtFeature StoresGCPPandasPythonPyTorchScikit-LearnSparkSQLXgboost
Reposted One Month AgoSaved
Easy Apply
Remote
San Diego, CA
Easy Apply
180K-212K Annually
Senior level
180K-212K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Own and evolve revenue calibration models tying CX interactions to revenue, design causal inference and experimentation frameworks, build LLM-powered classification/NLP pipelines, productionize models with Analytics Engineers, define segmentation and behavioral signals, and ensure statistical rigor for executive reporting and regulatory defensibility.
Top Skills: A/B TestingCausal InferenceGeminiGenerative AiGleanLibrechatLlmMlNlp
One Month AgoSaved
In-Office or Remote
San Diego, CA
124K-165K Annually
Senior level
124K-165K Annually
Senior level
Digital Media • Fintech • Information Technology • Machine Learning • Financial Services • Cybersecurity • Automation
Design, develop, and deploy production-grade generative AI and agentic systems (LLMs, RAG, AI agents). Build document intelligence, retrieval pipelines, vector search, and monitoring frameworks. Collaborate with risk, compliance, product, and engineering to deliver scalable, governed GenAI solutions in regulated environments.
Top Skills: AirflowAWSAws BedrockAzure AiCi/CdDatabricksEmbeddingsHugging FaceLangchainLanggraphMlflowOcrPrompt EngineeringPysparkPythonPyTorchRetrieval-Augmented Generation (Rag)SagemakerScikit-LearnSnowflakeSnowparkSparkSQLTensorFlowVector DatabasesVllm
13 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Artificial Intelligence • Big Data • Machine Learning
Lead end-to-end predictive analytics and machine learning initiatives, including forecasting, churn prediction, and risk modeling. Translate business needs into scalable ML solutions, build and deploy models on AWS SageMaker, develop production ML pipelines, and oversee monitoring, governance, explainability, and retraining. Collaborate with engineering and MLOps teams, communicate insights to stakeholders, and mentor junior data scientists while providing hands-on technical leadership.
Top Skills: Amazon SagemakerApache AirflowAWSAws LambdaAws Step FunctionsCi/CdGenerative AiInfrastructure As CodeKubeflowMlopsNumpyPandasPythonSagemaker PipelinesScikit-LearnXgboost
Reposted One Month AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Machine Learning • Software
The Staff Data Scientist will lead the development and deployment of ML and GenAI systems to detect billing errors and fraud in healthcare payments, collaborating with cross-functional teams.
Top Skills: AIData ScienceMachine Learning
Reposted One Month AgoSaved
Remote
San Diego, CA
220K-290K Annually
Senior level
220K-290K Annually
Senior level
Information Technology • Software
Build and productionize ML models and data infrastructure to analyze millions of chaos engineering experiments, detect and explain failures, recommend automated remediation, and integrate AI-driven failure analysis into Gremlin's product using techniques like causal inference, graph ML, time-series modeling, and reinforcement learning.
Top Skills: Agentic AiCausal InferenceChaos EngineeringData PipelinesFeature StoresGraph MlMlopsModel MonitoringModel ServingReinforcement LearningSite Reliability EngineeringTime-Series Modeling
Reposted 23 Days AgoSaved
In-Office
San Diego, CA
120K-165K Annually
Senior level
120K-165K Annually
Senior level
Fintech
Lead enterprise lead intelligence and signal strategy to define signals, scoring, and readiness for lead creation and prioritization. Partner with Marketing, Sales, RevOps, and Data teams, manage third-party data providers, and ensure lead quality and sales readiness.
14 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Big Data • Food • Mobile • Payments
Develop and deploy predictive and causal models for personalization, retention, monetization, and product strategy. Design experimentation and measurement frameworks, analyze user and marketing behavior, quantify business impact, and translate complex findings into strategic decisions. Collaborate with Product, Engineering, Marketing, and Data Product teams to build scalable data solutions. Mentor peers, promote rigorous model validation and governance, and apply Python, SQL, Snowflake, dbt, Airflow, Spark, and AWS to production-ready data science initiatives.
Top Skills: AirflowAWSBayesian InferenceCausal InferenceCcpaDbtExperimentation FrameworksGdprMachine LearningPythonSnowflakeSparkSQL
Reposted One Month AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Cloud • Information Technology • Software • Consulting • Web3
Seeking a skilled Data Scientist/Machine Learning Engineer to develop machine learning models, design AI systems, and collaborate in data analytics. Responsibilities include productionizing models, data engineering, and cross-functional collaboration.
Top Skills: AirflowAWSAzureCi/CdDockerGCPJIRAKubeflowKubernetesMlflowNumpyPandasPlantumlPythonPyTorchSparkTfx
15 Days AgoSaved
In-Office or Remote
San Diego, CA
Senior level
Senior level
Healthtech
Lead the design, development, deployment, and governance of advanced analytics, machine learning, and AI solutions using large healthcare datasets. Responsibilities include data preparation, statistical and predictive modeling, model monitoring, explainability, visualization, stakeholder communication, and translating findings into clinical and operational improvements. The role also mentors data professionals, advises leaders, manages initiative priorities and risks, and promotes responsible AI and Agile practices.
Top Skills: Advanced AnalyticsAgileArtificial IntelligenceData VisualizationDeep LearningFeature EngineeringGenerative AiMachine LearningNatural Language ProcessingOptimizationPredictive ModelingStatistical Modeling
One Month AgoSaved
Remote or Hybrid
San Diego, CA
Senior level
Senior level
Software
Design and deploy ML systems for enterprise search, recommendations, retrieval, and AI agents. Build scalable data/ML pipelines, evaluation frameworks, and metrics. Apply statistics, experimentation, and causal inference to guide product decisions. Collaborate cross-functionally, prototype LLM-based capabilities (embeddings, RAG), and mentor junior team members.
Top Skills: Agent Orchestration FrameworksEmbeddingsFoundation ModelsLlmsPythonRetrieval SystemsRetrieval-Augmented Generation (Rag)SQLVector Databases
One Month AgoSaved
Remote or Hybrid
San Diego, CA
179K-217K Annually
Senior level
179K-217K Annually
Senior level
Software
Lead design and deployment of ML systems for enterprise search, retrieval, recommendations, and AI agents. Build scalable data/ML pipelines, evaluation frameworks, and KPIs. Apply statistics, causal inference, experimentation, and analysis to guide product strategy. Prototype and productionize LLM-based features, mentor junior staff, and collaborate cross-functionally.
Top Skills: Agent Orchestration FrameworksEmbedding ModelsEmbeddingsFoundation ModelsLlmsPythonRetrieval SystemsRetrieval-Augmented Generation (Rag)SQLVector Databases
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