Top Remote Python Jobs in San Diego, CA

Develop, test, document, maintain, and integrate software applications supporting business needs. Responsibilities include writing clean code, fixing bugs, improving performance, troubleshooting, documenting systems, collaborating with engineers and business analysts, and participating in agile development processes.

Provide technical direction for GitLab Dedicated, a managed single-tenant SaaS platform. Lead architecture and transformation across resilience, failover, tenant orchestration, change management, automation, and platform integrations. Identify systemic reliability and scalability risks, establish reusable platform patterns, strengthen service ownership, and guide cross-team technical decisions. Mentor senior engineers and advance engineering excellence across the organization.

Design and evolve cloud-native services, distributed systems, and infrastructure platforms at scale. Lead architecture and technical direction across compute, networking, storage, AI infrastructure, HPC, GPU environments, and datacenter systems. Improve automation, observability, reliability, security, CI/CD, and developer productivity while collaborating across engineering organizations. Mentor engineers and contribute to architecture reviews and operational excellence for large-scale production platforms.

Build and operate distributed backend services and APIs for Airbnb’s global AirCover insurance platform. Develop policy, coverage, enrollment, and regional-rule capabilities; translate product and regulatory requirements into reliable code; and support experimentation, analytics, monitoring, and data protection. Collaborate with Product, Design, Data Science, Legal, infrastructure, security, and privacy teams. Participate in technical design, code reviews, on-call rotations, and ongoing reliability improvements.

Design, operate, and improve Recharge’s cloud-native infrastructure platform. Responsibilities include Kubernetes and GCP infrastructure management, troubleshooting production issues, maintaining observability and reliability, implementing new technologies, improving engineering standards and documentation, supporting security and automation, and participating in a 24/7 on-call rotation. The role also involves mentoring engineers and applying AI tools to improve team productivity.

Build and own user-facing features and core platform architecture across frontend, backend, and ML pipelines. Integrate AI workflows (LLMs, embeddings) for curriculum generation and automated evaluation. Manage end-to-end development: requirements, design, implementation, CI/CD, testing, observability, and iteration while collaborating with product, design, ML, and customer teams.

Develops and delivers resilient full-stack applications and services for Vantage’s reinsurance business. Responsibilities include application design, coding, debugging, testing, architecture discussions, risk management, roadmap estimation, stakeholder consultation, and coordination across project teams. The role promotes software engineering standards, DevSecOps, CI/CD, agile practices, innovation, and mentoring while building solutions with JavaScript, React, Node.js, Python, cloud, serverless, and modern infrastructure technologies.

Architects, deploys, and operates secure, highly available Kubernetes and cloud infrastructure for AI/ML workloads. Builds Terraform-based automation, GitOps workflows, CI/CD pipelines, observability, and security controls across cloud environments. Serves as a customer-facing technical SME, supporting solution architecture, technical scoping, demonstrations, documentation, and client handoffs. Participates in on-call operations, troubleshooting, root-cause analysis, and post-mortems.

Administer and harden production Linux systems, troubleshoot complex infrastructure and service issues, manage operating system lifecycles, and develop automation using Bash, Python, and Ansible. The role includes configuration management, security updates, monitoring, backups, recovery testing, incident ownership, documentation, controlled changes, and shared on-call support across physical and virtualized environments.

Performs thermal-hydraulic nuclear plant safety analyses for BWR reloads, designs, fuel projects, ECCS LOCA, containment, HELB, fire safe shutdown, and related applications. Collaborates with multidisciplinary teams, documents and presents technical results, mentors team members, develops training, improves processes, and ensures compliance with regulatory, customer, and quality requirements.

Develop and maintain high-reliability, high-throughput backend systems for managing security certificates and configurations. Responsibilities include designing scalable systems, building features, optimizing performance, working with relational and NoSQL databases, and collaborating with testing and SQA teams on deployments. The role requires project-based experience with Java, Spring, Spring Boot, Angular, Terraform, SQL, Linux/Unix, and database technologies.

Build and maintain customer-focused hands-on training labs and virtualized environments. Review technical content for quality, troubleshoot lab and UI issues, write PowerShell and Bash automation scripts, and deploy and score labs through automated publishing processes. Collaborate with customers, lab developers, instructional designers, and subject matter experts to create technically accurate learning experiences. Contribute to process improvements, platform administration, technical standards, and multiple concurrent projects.

Own the technical direction and delivery of WEX’s data acquisition platform. Build reusable, high-performance batch, CDC, and streaming ingestion services with schema validation, reconciliation, recovery, lineage, security, observability, and auditability. Lead architecture and code reviews, establish testing and CI/CD practices, mentor engineers, resolve cross-team dependencies, and support production escalations. The role requires hands-on development of scalable distributed systems and configuration-driven connectors.

Lead the reliability and scaling of Horizon AI’s autonomous platform for production GPU infrastructure. Harden agent dispatch with circuit breakers, retries, health-aware routing, and observable error handling. Build caching and event-streaming capabilities, determine and implement the orchestration strategy, introduce infrastructure as code, enable concurrent agent sessions, and own service standards, testing, CI, observability, and deployment practices. Serve as technical deputy and collaborate with Systems and SRE teams.

Build and scale Horizon AI’s platform reliability through caching, event streaming, resilient agent dispatch, observability, infrastructure as code, and safer deployment practices. The role focuses on health checks, circuit breakers, retries, backpressure, tracing, alerting, canary releases, traffic shifting, and rollback strategies. It requires measurable experience improving distributed-system reliability in Python and containerized environments, with Kubernetes or comparable orchestration expertise.

Lead competitive benchmarking for Elasticsearch across search, vector retrieval, analytical, and observability workloads. Build automated benchmark harnesses, datasets, query sets, and load profiles; design fair, reproducible comparisons; analyze latency, throughput, resource use, cost, and retrieval quality; investigate performance differences through profiling and controlled experiments; and translate findings into engineering improvements and technical publications.

Build and improve WebCompat dashboards, reporting tools, and broken-site screenshot capture pipelines. Collaborate with WebCompat and QA teams to translate triage and reporting needs into reliable internal tooling. The role involves web development, automation, web services, data views, and workflow improvements that help prioritize Firefox site compatibility issues.

Own Baseten’s internal identity and authentication infrastructure, including Okta architecture, SSO, MFA, lifecycle management, and application integrations. Build automated joiner, mover, and leaver workflows across HRIS, Google Workspace, MDM, and SaaS systems using scripting and APIs. Implement access controls, device trust, compliance processes, documentation, and audit evidence. Serve as a technical escalation point for IT Support and partner with Security on least-privilege access and SOC 2 requirements.

Develop GPU code generation and compiler optimizations for TensorRT to improve generative AI inference performance. Responsibilities include operator fusion, scheduling, specialization, profiling, debugging, numerical validation, and performance analysis. The role requires C++ software development and GPU architecture expertise, with collaboration across hardware, compiler, kernel, and deep learning teams. Preferred experience includes CUDA, MLIR, GPU kernels, Tensor Core optimization, inference frameworks, and low-level NVIDIA performance tools.

Develops maritime route optimization, vessel performance modeling, voyage analysis, simulation, and evaluation software for government and defense customers. The role improves optimization algorithms, models fuel consumption and operational constraints, builds explainable route recommendations, and collaborates with engineers and maritime specialists. Work spans Rust, Python, APIs, testing, algorithms, and production software supporting U.S. Government maritime applications.

Performs nuclear reactor thermal-hydraulic stability, plant noise, PRNM interface, reload, and safety analyses for BWR fleets and advanced reactor designs. Leads fuel projects, supports licensing and regulatory interactions, develops methodologies, prepares technical recommendations, mentors staff, and delivers training. Collaborates with engineering, licensing, project management, customers, and regulatory organizations while ensuring compliance with quality and safety requirements.

Provides technical leadership for the 340BCheck healthcare data platform. Designs architecture across front-end, back-end, data, infrastructure, and CI/CD; resolves complex distributed-systems problems; drives refactoring, observability, and cross-team initiatives; mentors senior engineers; communicates technical tradeoffs; and influences long-term engineering direction without direct people management.

Designs, implements, and supports Azure DevOps solutions for clients. Leads technical envisioning, solution design, cloud workload deployment, automation, CI/CD implementation, infrastructure transformation, troubleshooting, and remediation. Provides technical leadership to consultants and delivers client-facing cloud projects involving Azure infrastructure, DevOps pipelines, cloud automation, and emerging cloud technologies.

Develops advanced automated testing frameworks and leads test strategies for complex software applications across platforms. Oversees testing efforts, defect tracking, regression testing, and quality improvements while collaborating with developers and DevOps teams on CI/CD automation. Mentors junior staff, evaluates testing tools, supports the software development lifecycle, and applies data-driven insights to improve QA processes.

Design, build, operate, and maintain Grafana’s distributed search and storage systems. Deliver features from ideation through production, ensure reliability and performance, participate in on-call rotations, contribute to open-source projects, and collaborate remotely across teams. The role also involves mentoring colleagues, participating in technical design discussions, understanding customer needs, and continuously improving cloud-based services and engineering practices.