Top Remote Python Jobs in San Diego, CA

The Software Engineering Manager leads a full-stack team to develop SaaS applications for the insurance sector, focusing on architecture, collaboration, and best practices.

The Principal DevOps Engineer will architect the global cloud infrastructure, manage delivery pipelines, automate processes, and ensure operational health of a scalable distributed system. Responsibilities include designing AWS architecture, modernizing CI/CD pipelines, and developing monitoring dashboards.

The Senior Software Engineer will design and optimize recommendation algorithms, maintain data pipelines, and improve personalized user experiences using machine learning techniques and backend engineering skills.

The role involves designing and expanding backend systems, mentoring engineers, and executing technical strategies to modernize architecture and improve system performance.

As a Software Engineer II, you'll design and build backend services for a unified communications platform, collaborate with multiple teams, and manage medium-sized projects independently.

As a Product Security Engineer, you'll develop secure tools for engineering teams, conduct security reviews, and automate security processes to enhance Cedar's healthcare technology solutions.

Lead and grow a small Platform Testing team to define and execute a testing strategy that improves developer velocity and product reliability. Build cost-effective QA environments, implement service-to-service and configuration-driven testing, promote testing best practices, apply LLM-powered workflows, and partner with cross-functional stakeholders while managing hiring, coaching, and performance.

Own reliability, automation, and DevOps for Coinbase's corporate IAM platform: on-call/incident response, CI/CD and IaC pipelines, identity lifecycle tooling, observability and disaster recovery, documentation, and cross-team IAM advisement to ensure secure, scalable access for a global workforce.

Own reliability, monitoring, and incident response for AI infrastructure; build automation and CI/CD tooling; manage Kubernetes/Docker production workloads; partner with infrastructure, security, and compliance; improve observability and documentation; develop internal full‑stack tooling in Go or Python.

The Senior Platform Engineer will enhance infrastructure reliability and observability, focusing on AWS, Datadog, and HashiCorp Nomad for optimized performance and cost efficiency while collaborating with engineering teams.

Lead the engineering team for product delivery at Runpod, focusing on customer-facing features while managing roadmaps, team growth, quality, and cross-functional collaboration.

Lead architecture and delivery of Control Center platform capabilities (MCP tool registries, AI orchestration, access automation). Design agentic AI integrations, HITL workflows, and evaluation/guardrail frameworks. Own backend services, SLOs, observability, incident response, and operational readiness for Tier-1 systems. Drive cross-team technical direction, author TDDs, run design reviews, mentor engineers, and partner with Product and Security to deliver secure, scalable platform primitives.

Lead long-term technical vision and roadmap for the Overseer platform to ensure correctness across Coinbase fund flows. Own architecture, design and delivery of real-time detection, invariant frameworks, and partner APIs. Drive cross-team alignment, set engineering standards, mentor engineers, lead P0 initiatives, and apply generative AI responsibly to scale automated guardrails and enforcement capabilities.

Build and maintain developer platform tooling, automation, CI/CD, and Go-based CLI to improve developer productivity, reliability, and scalability for Huntresssecurity products. Implement AI-enabled workflows, support deployments in Azure and containerized environments, and collaborate with product teams to optimize architecture and operations.

Lead technical strategy and architecture for Coinbase Payments, building high-availability, low-latency payment rails and funds-flow systems. Drive cross-team initiatives, enforce financial correctness (idempotency, reconciliation, auditability), improve reliability and cost efficiency using observability data, mentor senior engineers, and align stakeholders across product, risk, and compliance to deliver scalable global payment solutions.

The Senior Software Engineer will design and maintain data systems, create data integration SDKs, and implement data security measures while collaborating with product teams and managing data pipelines.

The Senior Security Engineer will secure patient data, lead security initiatives, manage vulnerabilities, and advocate for a security culture in the organization.

The Full-Stack Software Engineer will enhance user interfaces, APIs, and develop features for AI applications while collaborating with teams and ensuring code quality.

The Manager of Software Engineering will lead the Developer Environments team, enhancing developer productivity through effective environment provisioning and CI/CD workflows while mentoring engineers and implementing system reliability improvements.

The Staff Software Engineer will enhance video capabilities, support live streaming and storage infrastructure, and collaborate on platform development. Responsibilities include coding, mentoring, and ensuring platform reliability for millions of users.

The Senior Fullstack Engineer will build and manage enterprise authentication systems, improve user session management, ensure security compliance, and support internal API usage across services, while enhancing performance and reliability.

As a Senior Site Reliability Engineer, you'll design and build complex systems, support Atlas platform operations, automate processes, and ensure high availability of services.

Design and maintain cloud infrastructure software using Go, collaborate on product requirements, troubleshoot code, and contribute to architectural decisions.

As a Fullstack Engineer, you'll design, build, and operate web applications, collaborating with product teams and mentoring peers while ensuring best practices in coding and system architecture.

The Senior Staff Software Engineer will architect Affirm's lakehouse analytics platform, lead data governance efforts, mentor engineers, and collaborate across teams to optimize data solutions using Snowflake and other big data tools.