Top Remote Python Jobs in San Diego, CA

Reposted 7 Days AgoSaved
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Remote or Hybrid
Remote San Diego, CA
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100K-130K Annually
Senior level
100K-130K Annually
Senior level
Automotive • Big Data • Insurance • Software • Transportation
The Senior QA Engineer will develop and maintain automation frameworks, write test cases, and ensure software quality while collaborating with various teams. Key responsibilities include managing testing lifecycles and participating in system design discussions.
Top Skills: AWSCapybaraCucumberCypressGraphQLJavaScriptJmeterPlaywrightPostmanPythonRubySeleniumSQLTypescript
Reposted 7 Days AgoSaved
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Remote
Remote San Diego, CA
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150K-200K Annually
Senior level
150K-200K Annually
Senior level
Artificial Intelligence • Cloud • Software • Infrastructure as a Service (IaaS)
As a Site Reliability Engineer, you will ensure system stability and resilience, define reliability standards, and automate operational processes while collaborating cross-functionally to improve performance and reduce incidents.
Top Skills: BashCi/CdDockerGoGrafanaKubernetesLinuxPrometheusPython
Reposted 7 Days AgoSaved
Remote or Hybrid
Remote San Diego, CA
115K-130K Annually
Senior level
115K-130K Annually
Senior level
AdTech • Consumer Web • Digital Media • eCommerce • Marketing Tech
The Senior IT Infrastructure Engineer will enhance automation and integration efforts while managing cloud services, CI/CD pipelines, and Kubernetes operations.
Top Skills: AnsibleArgo CdAWSAzureCrossplaneDaggerDockerGCPGitGoGrafanaHelmJavaScriptJenkinsKubernetesN8NPrometheusPythonRestSoapTerraformTypescript
Reposted 7 Days AgoSaved
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Remote or Hybrid
Remote San Diego, CA
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196K-294K Annually
Senior level
196K-294K Annually
Senior level
Artificial Intelligence • Cloud • Software
As a Senior Software Engineer in Trust & Safety, you'll analyze threats, design systems for abuse detection, and collaborate with teams to implement scalable defenses.
Top Skills: AWSJavaScriptLlmPythonTypescript
Reposted 7 Days AgoSaved
Remote or Hybrid
Remote San Diego, CA
125K-150K Annually
Senior level
125K-150K Annually
Senior level
AdTech • Consumer Web • Digital Media • eCommerce • Marketing Tech
The Senior Software Engineer will design and build scalable AI/ML backend systems, develop data pipelines, and collaborate with cross-functional teams to implement ML-driven features while ensuring system performance and documentation.
Top Skills: Apache AirflowApache BeamAWSDockerElasticsearchGCPGrafanaKafkaKibanaKserveKubernetesNode.jsPythonTypescriptVector DatabaseVertex Ai
Reposted 7 Days AgoSaved
Remote
Remote San Diego, CA
203K-274K Annually
Senior level
203K-274K Annually
Senior level
Artificial Intelligence • Cloud • Consumer Web • Productivity • Software • App development • Data Privacy
Design and re-architect the Identity systems at Dropbox to support multi-product capabilities, mentor junior engineers, and ensure software excellence.
Top Skills: GoPython
Reposted 7 Days AgoSaved
Remote
Remote San Diego, CA
82K-105K Annually
Junior
82K-105K Annually
Junior
Software
The Marketing Backend Developer will build and maintain backend services and APIs for marketing operations, ensuring reliable data flow and system integrations, with a focus on performance and scalability.
Top Skills: AWSCloudFormationCSSDjangoFlaskHTMLJavaScriptMarketoNext.JsNode.jsPythonReactRubySalesforceSamSvelteTerraformVue
Reposted 7 Days AgoSaved
Remote or Hybrid
Remote San Diego, CA
75K-257K Annually
Senior level
75K-257K Annually
Senior level
Consumer Web • Coupons • Healthtech • Social Impact • Pharmaceutical
The Sr. Software Engineer designs, implements, and maintains scalable cloud services, contributes to team processes, and acts as a subject matter expert while leading projects and mentoring others.
Top Skills: AirflowAWSAws Step FunctionsAzureC#CloudwatchDatadogDockerGCPGoJavaKubernetesLuigiPythonReactRustSentrySumo Logic
8 Days AgoSaved
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Remote or Hybrid
Remote San Diego, CA
Easy Apply
147K-210K Annually
Senior level
147K-210K Annually
Senior level
Big Data • Cloud • Software • Database
Design and implement cloud-native storage and replication features for MongoDB. Develop production C++ code, write tests (C++, JavaScript, Python), diagnose bugs and performance regressions, handle customer escalations, lead cross-team projects, mentor engineers, and collaborate on product roadmaps.
Top Skills: CC++Distributed SystemsJavaScriptMongoDBMulti-Threaded ProgrammingPerformance ProfilingPythonRaft Consensus Protocol
8 Days AgoSaved
Remote or Hybrid
Remote San Diego, CA
125K-210K Annually
Senior level
125K-210K Annually
Senior level
Artificial Intelligence • Cloud • Sales • Security • Software • Cybersecurity • Data Privacy
Lead a CI/CD/IDP engineering team to improve release velocity, security, and compliance. Own Secure SDLC, software supply chain controls, GitOps-driven pipelines, developer self-service, pipeline performance/FinOps, and alignment with audits (FedRAMP/SOC 2). Mentor engineers, set roadmap, and deliver audit-ready release processes at scale.
Top Skills: Artifact SigningBackstageCi/CdCloud PlatformsGitopsGoInfrastructure As CodeInternal Developer PlatformsJavaJavaScriptPythonSastSbomScaSecrets Detection
8 Days AgoSaved
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Remote
Remote San Diego, CA
Easy Apply
146K-164K Annually
Senior level
146K-164K Annually
Senior level
Insurance
Design, build, test, and maintain backend services and APIs for an insurance platform. Integrate external services and data providers, improve system stability, performance, and scalability, participate in architecture discussions, mentor teammates, and support internal tooling and deployment practices.
Top Skills: Aiven DebeziumArcgisBigQueryCircleCICloud FunctionsCloud RunComposer/AirflowDatadogDonutFivetranGcp GcsGitGoGCPJupyter NotebooksKafkaKubernetesNuxtPostgresPub/SubPythonRSlackSQLTailwindTerraformVuejsWebpackZoom
8 Days AgoSaved
Easy Apply
Remote or Hybrid
Remote San Diego, CA
Easy Apply
200K-230K Annually
Senior level
200K-230K Annually
Senior level
Artificial Intelligence • Machine Learning
Lead development of AI-assisted reliability tooling, own incident response end-to-end, improve observability and SLO/SLI frameworks, scale single-tenant SaaS operations, mentor engineers, and reduce recurring operational toil through engineering and automation.
Top Skills: Cloud PlatformsGoKubernetesLinuxLlm/Ai ToolingLogs And TracingObservability ToolingPythonSlo/Sli Frameworks
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8 Days AgoSaved
Remote
Remote San Diego, CA
Senior level
Senior level
Artificial Intelligence • Machine Learning • Software • Defense
Build and ship production-grade agentic AI developer tools and a coding harness to modernize legacy systems. Design integrations across source control, CI/CD, security scanners, and cloud services. Partner with customers and product teams to iterate on AI-native workflows, ensure cybersecurity compliance, and scale agentic systems for defense missions.
Top Skills: Agent2Agent (A2A)AWSLanggraphModel Context Protocol (Mcp)Node.jsOpenai SdkPostgresPythonReactTailwindTypescript
8 Days AgoSaved
Easy Apply
Remote or Hybrid
Remote San Diego, CA
Easy Apply
170K-221K Annually
Senior level
170K-221K Annually
Senior level
Food • Software
Senior Backend Engineer responsible for building, deploying, and monitoring backend applications. Collaborate with product and cross-functional teams to design/version APIs, build event-driven/asynchronous systems, improve performance and reliability, and drive CI/CD and observability best practices. Ship high-quality, well-tested features and support platform scalability and maintainability.
Top Skills: Apis (Public/Partner-Facing)AWSBackground Job ProcessingCi/CdCloud InfrastructureContainerized DeploymentsDocker (Containerization)GCPMessage QueuesObservabilityPython
Reposted 8 Days AgoSaved
Easy Apply
In-Office or Remote
Remote San Diego, CA
Easy Apply
200K-240K Annually
Expert/Leader
200K-240K Annually
Expert/Leader
Artificial Intelligence • Hardware • Healthtech • Software
Lead the design and execution of radar sensing platforms and wireless communication sub-systems, overseeing development, optimizing designs, and ensuring quality and compliance. Collaborate across teams and mentor members while troubleshooting complex issues in RF/mmWave design.
Top Skills: Ansys HfssCadence Allegro/CaptureIot CommunicationsKeysight AdsMmwave TechnologyPythonRf Design
Reposted 8 Days AgoSaved
Remote or Hybrid
Remote San Diego, CA
185K-284K Annually
Senior level
185K-284K Annually
Senior level
Automotive • Big Data • Information Technology • Robotics • Software • Transportation • Manufacturing
The Sr Staff AV Behavior Safety Engineer leads safety validation for GM's autonomous driving systems, influences launch decisions, and collaborates across teams for safety standards and performance metrics in AV behavior development.
Top Skills: AWSDockerGitGoogle Cloud PlatformJavaJIRAKubernetesAzureMlflowNumpyPandasPower BIPysparkPythonPyTorchRScikit-LearnSQLTableauTensorFlow
Reposted 8 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
139K-245K Annually
Mid level
139K-245K Annually
Mid level
Blockchain • eCommerce • Fintech • Payments • Software • Financial Services • Cryptocurrency
As an ASIC Validation Engineer, you'll bridge custom mining silicon design and operation, debugging issues, developing test infrastructure, and validating functionality with ASIC designers.
Top Skills: AsicFpgaI2CJtagLogic AnalyzersOscilloscopesPower SuppliesPythonSpiUart
Reposted 8 Days AgoSaved
Remote or Hybrid
Remote San Diego, CA
176K-265K Annually
Senior level
176K-265K Annually
Senior level
Cloud • Healthtech • Social Impact • Software • Biotech
The Software Engineer will enhance developer experience at Benchling by building production release tooling, improve workflows, and collaborate with teams to scale processes. Responsibilities include developing efficient development tools and championing engineering patterns.
Top Skills: DockerKubernetesNode.jsPythonWeb Framework
9 Days AgoSaved
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Remote
Remote San Diego, CA
Easy Apply
165K-190K Annually
Senior level
165K-190K Annually
Senior level
Healthtech • Insurance • Sales • Software
Build full-stack features for a web-based broker platform serving Medicare customers. Work across frontend and backend, influence architecture, reduce technical debt, collaborate with product and design, use AI-powered developer tools, and mentor engineering best practices to scale the platform.
Top Skills: Ai-Powered Developer ToolsAWSDjangoJavaScriptPythonReactVue
9 Days AgoSaved
Remote
Remote San Diego, CA
166K-269K Annually
Senior level
166K-269K Annually
Senior level
Consumer Web • eCommerce • Machine Learning • Software • Sports • Analytics
Lead design and build of scalable AWS cloud-based backend services and APIs powering web and mobile customer experiences. Own end-to-end feature delivery, improve grading and authentication workflows for scale and reliability, leverage AI tools to accelerate development, and provide technical leadership and mentorship across teams.
Top Skills: AWSC#Claude CoworkCodexEvent-Driven ArchitecturesJavaMicroservicesNext.JsPythonReactServerless
Reposted 9 Days AgoSaved
Remote
Remote San Diego, CA
150K-220K Annually
Mid level
150K-220K Annually
Mid level
Artificial Intelligence • Machine Learning • Natural Language Processing • Software • Conversational AI
Design and implement secure, scalable backend services for voice agents, integrate AI models and telephony, improve inference, debug concurrent systems, and collaborate with Product to deliver features end-to-end.
Top Skills: CC++GitPythonRustUnix
Reposted 9 Days AgoSaved
Remote
Remote San Diego, CA
150K-220K Annually
Mid level
150K-220K Annually
Mid level
Artificial Intelligence • Machine Learning • Natural Language Processing • Software • Conversational AI
Lead the design and implementation of backend services for data cataloging and ML training systems, focusing on performance and scalability.
Top Skills: CC++PythonRustUnix
Reposted 9 Days AgoSaved
Remote
Remote San Diego, CA
140K-200K Annually
Mid level
140K-200K Annually
Mid level
Artificial Intelligence • Machine Learning • Natural Language Processing • Software • Conversational AI
As a Solutions Architect at Deepgram, you'll engage with customers post-sales to resolve complex technical issues, create scalable solutions, and enhance support processes, using your engineering skills and experience in customer-focused roles.
Top Skills: AWSAzureC/C++DockerGCPJavaScriptKubernetesPythonRustTypescript
Reposted 10 Days AgoSaved
Easy Apply
Remote or Hybrid
Remote San Diego, CA
Easy Apply
Internship
Internship
Cloud • Information Technology • Security • Software • Cybersecurity
This internship role focuses on SRE skills, requiring collaboration and problem-solving in dynamic environments for Zscaler's Zero Trust Exchange team.
Top Skills: AnsibleAws EcsKubernetesLinuxPythonTerraform
Reposted 10 Days AgoSaved
Easy Apply
Remote or Hybrid
Remote San Diego, CA
Easy Apply
200K-250K Annually
Expert/Leader
200K-250K Annually
Expert/Leader
Marketing Tech • Real Estate • Software • PropTech • SEO
Lead the architecture and development of robust data pipelines and backend services for MLS data, integrating AI solutions and ensuring data quality.
Top Skills: AirflowApache KafkaAWSEmrFlinkGraphQLJavaKubernetesPythonRestSparkSQL
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