Top Remote Python Jobs in San Diego, CA

Leads the design, automation, operation, and scaling of infrastructure across on-premises data centers, GCP, and AWS. Responsibilities include infrastructure as code, configuration management, networking, load balancing, DNS, monitoring, observability, distributed systems administration, documentation, technical direction, project leadership, and mentoring. The role requires deep Linux, hardware, networking, cloud, storage, backup, and Python automation expertise.

Design, deploy, automate, and support large-scale cloud network infrastructure across AWS, Azure, and GCP. Manage firewalls, Kubernetes networking, VPNs, DNS, BGP, monitoring, infrastructure as code, and network performance. Lead technical roadmaps, design reviews, troubleshooting, engineer onboarding, and team direction while participating in on-call support and occasional travel.

Support and improve reliability, scalability, and performance of large-scale databases across cloud and on-prem. Build automation, Kubernetes operators, GitOps workflows, and tooling in Go or Python; implement observability, capacity planning, failover, backups, schema migrations, and self-healing systems; partner with application teams and leverage AI to improve operations and engineering productivity.

Design, build, and operate secure cloud-native and edge infrastructure for classified and commercial environments. Own end-to-end platform outcomes, harden artifact pipelines for signed builds across cloud and air-gapped deployments, embed with product teams to advise on secure deployments, and support compliance/audit activities (STIGs, CVE remediation) to enable operation in IL5/IL6/JWICS environments.

Lead a Reliability Platform Engineering team to build operational intelligence, observability, and AI-driven tooling that improves production availability, resiliency, and operational governance. Partner with Platform, SRE, Infrastructure, and Product teams to define reliability standards, prioritize investments, and deliver scalable reliability and automation solutions.

Lead and deliver quarterly goals for a backend team; guide engineers through ambiguous problems; collaborate with product, design, and analytics; identify and resolve project and technical issues; ensure operational availability and on-call readiness; set code and design quality standards; and mentor and develop team members.

Lead design and delivery of enterprise-grade integrations between Samsara and customer systems. Own architecture, implementation, mentorship, cross-functional coordination, troubleshooting, automation, and customer-facing technical enablement for complex B2B integrations.

Build automated reliability and self-healing platform tooling to protect production at scale. Improve incident management, reduce alert noise, evolve observability (monitoring, SLOs, performance detection), and develop AI-driven operational automation. Partner with product teams to diagnose reliability gaps, drive incident prevention, and champion operational excellence and best practices across engineering.

Lead architecture, modernization, and development of Group Insurance applications. Modernize mainframe monoliths into Java microservices and micro-frontends on cloud, mentor distributed Agile teams, collaborate with enterprise architecture, product owners and infrastructure, and enable test automation and integrations. Approximately 10% domestic travel.

Own and automate end-to-end employee lifecycle and shared IT infrastructure using infrastructure-as-code and SRE practices. Manage ITSM platform and AI-driven virtual agents, build integrations (Okta, Workday, JAMF, Google Workspace, Slack, Zoom, GitLab), instrument metrics, ensure reliability and compliance, and mentor support engineers.

Lead a team of Technical Solutions Engineers to triage, diagnose, and resolve production issues across Bestow's platform. Own support queue, incident command, SLAs, runbooks, automation, observability, and partner escalation while contributing ~20% production-level code and converting recurring issues into funded roadmap work.

Lead the design and evolution of predictive maintenance platform, build and scale ML-powered features, and mentor other engineers.

Lead full‑stack development and architecture for Spark’s broker platform. Deliver customer‑facing features, partner with product/design, mentor engineers, resolve technical debt, and set engineering standards while using AI developer tools.

Twelve-week virtual fellowship teaching Palantir Foundry and AIP through live sessions and projects. Expect 5–10 hours/week, hands-on training, mentorship, certification opportunity, and potential interviews for employment. Program is unpaid.

Support deployments and post-sale operations of Copia's DeviceLink and Source Control in industrial OT environments. Provide technical support, lead pilots, enable customers, advise on OT network security, collaborate with sales and engineering, and travel up to 25% for on-site assistance.

Own architecture and delivery of core ledger and transaction processing systems. Design and build highly available, high-performance backend services, drive cross-team technical initiatives, establish platform standards, mentor engineers, and embed AI to improve operations and workflows.

Responsible for leading a team of engineers, supporting product development, identifying technical issues, and ensuring high-quality code delivery in backend systems at scale.

Build and own a vendor schema registry and semantic validation pipeline that ingests OpenAPI/Swagger/Smithy specs, tracks schema evolution, detects semantic and breaking changes, and provides SDKs and developer tooling to safely map vendor APIs into a canonical knowledge graph used by downstream teams.

Develop a platform for liquidity and loan collateralization. Responsibilities include building and integrating data pipelines, creating user experiences, and collaborating with teams for system design.

Develop ML/RL models and infrastructure for AV simulations, optimize training loops, and support project timelines in autonomous vehicle tech.

Lead SRE efforts for DFIN SaaS: ensure availability, performance, scalability, and automation. Implement monitoring, CI/CD, IaC, container orchestration, AI-enhanced observability, incident response, RCA, and runbook automation while collaborating across engineering teams.

Lead the design and roadmap for global Active Directory and identity infrastructure, implement Identity-as-Code and GitOps automation, own incident escalation and observability, define delegation/tiered administration, integrate applications with Okta and cloud identity, mentor teams, and publish identity architecture and security best practices.

Design, build, and maintain People systems automations and integrations (Workato, Workday, Greenhouse, Slack) using production-quality code. Improve CI/CD, reliability, observability, and AI-driven automation (Claude, MCP). Serve as technical lead for People Technology, partner with stakeholders, and drive scalable, maintainable automation solutions.

Lead technical strategy and delivery for backend marketplace/search systems. Collaborate with PM, design, and analytics; own operational reliability, monitoring, on-call, testing, and runbooks; set code/design standards; drive major feature delivery and deprecations; mentor and develop engineering talent.

As a Senior Software Engineer, you'll support projects from conception to completion, build and extend React applications, and contribute to Vetcove's platform development.