Top Remote Python Jobs in San Diego, CA

Support and improve internal technology infrastructure by troubleshooting applications, servers, networks, and databases; building automations and integrations; managing SQL, cloud infrastructure, DevOps processes, CI/CD pipelines, deployments, and version control; improving system reliability and scalability; collaborating with teams; documenting procedures; and applying security best practices.

Develop and maintain Python software applications, backend services, APIs, integrations, and database solutions. Responsibilities include troubleshooting, testing, deployment, code review, performance monitoring, documentation, and collaboration with a distributed remote team. The role requires independent work, strong communication, and reliable delivery of maintainable, scalable software.

The Sr. Full Stack Developer will design and build full-stack applications, focusing on AI-powered solutions, and lead code reviews while mentoring junior engineers in the Advanced Technology Center.

Work as a Python development intern building applications and APIs, processing and analyzing data, working with databases and data pipelines, contributing to system architecture, writing clean documented code, and collaborating with the team. Strong emphasis on backend development, SQL, ORMs, and REST API design with potential conversion to full-time.

Lead architecture, implementation, and operations of the cloud platform on Google Cloud. Improve platform patterns (networking, IAM, security, observability, automation), drive CI/CD and IaC standards, mentor engineers, manage incidents, and align infrastructure with product needs to enable reliable, scalable production workloads.

Hands-on technical leader and core individual contributor building cloud-native defense/intelligence software. Drive architecture, code reviews, feature delivery, and mentor a small Agile team while implementing DevOps, CI/CD, and robust AWS/EKS-based deployments.

Owner of on-prem reliability and escalations: reproduce and resolve L2/L3 issues across heterogeneous Kubernetes environments, build diagnostics and automation, improve CI and e2e test stability, establish performance baselines, harden install/upgrade flows, and write tooling in Python/Go/Rust to reduce repeat incidents.

Perform end-to-end, integration, system, user acceptance, and automated testing for software applications. Create test strategies, plans, documentation, and automated test cases; execute tests; assess results; and track defects through resolution. Translate business requirements into technical requirements, identify risks, troubleshoot application issues, and collaborate with engineering and development teams. Support product implementations, training, technical escalations, and quality assurance oversight across project workstreams.

Build and maintain data-intensive, interactive web products across the full stack. Architect and implement API and frontend features, validate FastAPI responses with Pydantic, access Postgres via SQLAlchemy, optimize performance and scalability, implement testing and QA, participate in code reviews, refine UX, and help define engineering processes at an early-stage company.

As a Software Engineer - Backend, you will develop products and manage engineering infrastructure, focusing on system design, security, and code quality.

As a Senior Software Engineer, you will develop new products and improve engineering infrastructure while taking ownership of product deliverables and enhancing technical architecture.

Lead full-stack engineering for a browser extension and backend services, drive AI integrations with strong data privacy, mentor and recruit engineers, manage complex integrations, ensure code quality and SOC2 compliance readiness, and make architectural decisions to scale the platform.

Leads engineering teams delivering secure, scalable software for private banking and payment platforms. Oversees architecture, development, integrations, data flows, production stability, regulatory compliance, testing, release practices, risk reduction, and continuous improvement. Partners with product, architecture, security, risk, and business stakeholders while coaching engineers, aligning capacity to priorities, and advancing AI-native development tools.

Join Canonical as a graduate software engineer to write high-quality code across the open source stack, work on Linux system-level and application projects, engage with communities, respond to customer issues, and develop security-aware software while collaborating remotely and attending biannual in-person team sprints.

Join as an early founding full-stack engineer to architect, build, and deploy a scalable platform serving AI-driven voice applications. You will own frontend and backend development, design infrastructure with the CTO, and deliver reliable production systems for enterprise customers.

Work across frontend and backend to design, build, and ship annotation and review features; implement ingestion, storage, user management, and annotation pipelines; integrate model inference into workflows; optimize performance for large images/videos; design APIs and collaborate with product, operations, and annotators.

Full Stack Engineer responsible for building responsive frontends (JS/TS, React preferred) and backend services (Python, Go, or Node.js/TypeScript), designing RESTful APIs, managing databases (Postgres/MongoDB), and deploying on cloud (AWS). Collaborate with teams, optimize performance, and apply DevOps practices (Docker, Kubernetes, CI/CD). Requires strong problem-solving, communication, and 3+ years of experience.

Design and build a scalable, responsive UI; lead frontend architecture and optimization; apply UI/UX best practices; integrate with backend APIs; ensure high web performance and deploy user-facing features.

Build and maintain end-to-end product features across frontend, backend, and databases. Design APIs, authentication, data models, integrations, and AI-assisted workflows. Ship production-ready SaaS components, debug across the stack, improve reliability and performance, and collaborate on product and architecture decisions in an early-stage startup.

Work with the development team to build and debug web applications: write Python backend code, create responsive HTML/CSS/JavaScript frontends, integrate frontend and backend, participate in code reviews and testing, learn frameworks and document progress.

Customer-facing engineer who builds demos, prototypes, and workshops to drive pre-sales and adoption of Motorq's connected-vehicle and AI capabilities; partners with sales, customer success, and product teams and travels regularly to customer sites.

As a Design Team Member, you will implement digital blocks to full-chip designs, focusing on physical design constraints and ensuring manufacturability by coordinating with various engineering teams.

The Design Verification Engineer ensures functional correctness of IPs and SoCs by developing verification environments, driving coverage closure, and automating tasks to enhance productivity.

Design and implement PostgreSQL internals and indexing/query features for large-scale document workloads, extend query engine with BSON-aware operators and custom scan nodes, tune index pruning and storage, profile distributed systems for performance, collaborate with open-source DocumentDB/PostgreSQL communities, and participate in design/code reviews.

Build and own the technical roadmap: design AI-first interfaces and APIs, architect scalable ETL pipelines, develop data models for ML features, ship autonomous B2B workflows (PO generation, vendor sync, schedule optimizations), and establish engineering standards, CI/CD, and mentoring.