Top Remote Python Jobs in San Diego, CA

Design, build, test, deploy, and maintain software applications. Mentor engineers, research and implement solutions, support Agile development, deploy AI models (Bedrock), design auto-scaling systems, and create MCP/API custom connectors while collaborating with stakeholders.

Lead, mentor, and manage multiple software engineering teams; own hiring, performance management, and staffing. Drive engineering standards, architecture, deployments, and lean improvements. Ensure AWS-based solutions with autoscaling, deploy AI models (Bedrock), build MCP/API connectors, and coordinate security policy compliance.

Lead end-to-end design, development, and quality of cloud-based enterprise software solutions for caregivers. Define quality criteria, estimate costs, manage risks and engineering processes, integrate systems, and act as technical leader across large, complex projects.

Build and maintain the core backend product: design and implement features, take ownership of end-to-end outcomes, iterate and fix bugs without a QA team, collaborate with product on scoping, and contribute to company culture and hiring.

Own and evolve the platform-as-product used by engineering teams: improve reliability and observability, build test infrastructure and CI/CD tooling, optimize infrastructure cost and strategy, maintain infrastructure-side compliance (SOC 2/HIPAA), and serve as first-response for platform on-call incidents.

The engineer will design, characterize, and develop coherent optical transceivers, focusing on digital-optical integration and performance optimization.

The Signal Integrity Engineer will simulate high-speed PCB channels, provide guidance to designers, and design test boards. Requires extensive experience in SerDes simulation.

Responsible for developing mechanical test equipment, leading design efforts, performing FEA and thermal analyses, and maintaining product documentation. Collaborates with cross-functional teams, and surveys materials and vendors for optics activities.

The engineer will develop high-speed analog ICs, oversee product development phases, and collaborate with various engineering teams to ensure product performance and reliability.

Build and maintain production-grade integrations between Mia and EHRs, practice management systems, and data warehouses. Lead technical discovery with customer IT, implement APIs and data pipelines, provide Tier 2/3 support, document integrations, and improve automation of integration processes while serving as the primary technical contact for clients.

Perform technical code review and analysis to determine originality and function, prepare memos and expert reports, rebut other experts, communicate with counsel and clients, prepare testifying experts, manage multiple engagements, and supervise junior staff.

Build and ship end-to-end features in Next.js/TypeScript and Python/FastAPI; design scalable, low-latency systems for voice/SMS/chat; implement secure EHR integrations (FHIR/HL7); architect data storage and pipelines (Postgres, Redis, S3) with HIPAA/SOC-2 controls; own infra as code (Terraform, Helm), CI/CD, testing, and production reliability; collaborate cross-functionally and mentor junior engineers.

Build and maintain scalable backend microservices and developer-facing APIs, lead projects end-to-end, collaborate with product and engineering teams, design secure/versioned APIs, and manage cloud infrastructure using IaC.

Design, build, and maintain AWS cloud infrastructure and IaC for data and application solutions. Support data teams, implement CI/CD pipelines, enforce security best practices, optimize costs, monitor and troubleshoot platform operations, and collaborate across stakeholders using agile methods and JIRA.

Design, deploy, and maintain Azure cloud infrastructure using Infrastructure as Code (Bicep, Terraform, ARM) and automation. Collaborate with developers, manage code in Azure DevOps/Git, administer Databricks and Power BI, implement security (Active Directory), support CI/CD and disaster recovery, mentor engineers, and participate in off-hour maintenance escalations.

Design, automate, deploy, and secure AWS and hybrid infrastructure using Terraform and CI/CD tooling. Build reusable IaC modules, maintain DevOps pipelines, implement logging/monitoring, and ensure compliance with zero-trust and frameworks (NIST/CIS/ISO). Collaborate across engineering, security, networking, and data teams to support mission continuity, DR, and documentation for federal environments.

Build and extend Pulumi Cloud features and SDKs, design scalable cloud systems, write production full-stack code (Angular/TypeScript, Node.js, Go), integrate LLMs/AI into products, drive roadmap and mentor engineers while focusing on security and reliability.

Provide Tier 3 technical support and incident management for a large-scale trading platform, troubleshoot distributed systems and backend code, collaborate with DevOps and backend teams, build automation tools and monitoring, maintain knowledge base, and engage with Java/Spring Boot microservices, APIs, blockchain tech, and AI-assisted troubleshooting.

Join the Trading Engine team to develop and maintain client-facing open-source libraries, act as an SME for REST and WebSocket trading APIs, and work directly with large clients to design and optimize trading algorithms and integrations.

Design, build, and maintain HL7/FHIR interfaces using Mirth Connect and HealthShare. Support production hospital integrations, troubleshoot incidents, perform root-cause analysis, participate in platform consolidation, DR/HA validation, and collaborate with vendors and IT teams for interoperability and standards implementation.

Join Goodie AI's AI Lab to design and build scalable front-end solutions and contribute to backend infrastructure and DevOps. Lead React development, collaborate with designers and data scientists, integrate APIs, ensure performance, and participate across the full application lifecycle to deliver high-quality AI platform features.

Design, implement, and manage GCP infrastructure using Terraform; architect compute, storage, and networking; integrate Vertex AI and BigQuery for ML and analytics; configure Wiz Security Control for continuous monitoring; implement automation, scripting (Python/Bash), security, and compliance; collaborate with cross-functional teams.

SDET focused on data reconciliation, complex SQL, and ETL testing. Build and automate test frameworks, validate ETL pipelines and data warehouses, write optimized SQL for data validation, perform root-cause analysis of discrepancies, and ensure data integrity between source and target systems.

Design, govern, and maintain hybrid cloud platform architecture and reference implementations. Lead cloud service selection, security-by-design, DevOps/GitOps, infra-as-code, container and Kubernetes platform implementations, monitoring, and architecture reviews. Partner with security and engineering teams to drive standards, blueprints, and operational practices.

Lead mission readiness and performance across the Mission Foundry lifecycle: define V&V campaigns, streamline AI&T workflows, analyze on-orbit telemetry, improve autonomy and fault management, feed performance data into design iterations, and support internal tooling roadmaps to scale spacecraft production and operations.