Top Remote Principal Software Engineer Jobs

Lead the technical direction for production engineering in NVIDIA DGX Cloud, focusing on Kubernetes operations, automation, and reliability for GPU clusters.

Lead technical aspects of an engineering team, design and revamp systems, improve efficiency, mentor engineers, and contribute to product strategy.

The Principal Software Engineer - Backend drives technology direction for backend systems, ensures service reliability, and mentors teams while shaping architecture and standards across Autodesk's systems.

As a Senior Principal Software Engineer, you'll develop a unified data platform, architect infrastructure, implement APIs, and mentor teams, focusing on data processing and reliability.

The Principal Software Engineer will design and implement distributed systems, APIs, and data pipelines utilizing machine learning and large language models to enhance B2B marketing intelligence.

Lead the design and implementation of high-performance PoP infrastructure, optimize networking software, and mentor engineering teams at Blue Origin.

Lead technical vision and architecture for a cloud-native, event-driven health platform. Guide teams from prototype to production, ensure reliability, security, performance, and strong engineering practices (testing, observability, CI/CD), mentor senior engineers, and collaborate with product and architecture stakeholders to drive platform roadmaps and execution.

Lead design, architecture, and hands-on implementation of scalable healthcare SaaS systems. Drive interoperability (HL7, FHIR, EDI), mentor engineers, liaise with stakeholders, manage technical risk, and ensure quality, performance, security, and innovation.

Founding engineer responsible for architecting and building core product systems, writing scalable Python backend code, designing and maintaining AI/ML infrastructure, instituting best development practices (testing, CI/CD), collaborating on product roadmap, and mentoring future engineers.

Design, build, and improve Elasticsearch distributed-systems components for scalable, concurrent, and consistent indexing. Maintain cluster coordination for performance and resilience, push system scale limits, investigate performance and concurrency issues, support operations/support engineers, and lead projects involving multiple engineers from design through delivery.

The Principal Software Engineer leads innovation and technical direction for Fullbay's SaaS platform, focusing on scalable systems, mentoring, and cross-organizational impact, while improving software development practices.

Lead full‑stack development and ownership of ZoomInfo's Mesh AI platform: build React frontends, backend APIs, cloud infrastructure, LLM integrations, orchestration workflows, developer SDKs, respond to incidents, ensure quality, and mentor engineers.

Designs, develops, and maintains medical device software across the full lifecycle, ensuring regulatory and quality compliance. Leads architecture, implementation, testing, documentation, code and design reviews, and multi‑departmental projects. Provides technical support, resolves product complaints and safety issues, manages vendors, and chairs project meetings to deliver safe, reliable software for clinical use.

Lead design and development of multi-component OpenShift/Kubernetes software, drive SDLC and AI-driven engineering practices, collaborate across internal and open-source communities, mentor senior engineers, and deliver high-impact distributed systems features with robust CI/CD, container runtime, and Git-based workflows.

Develop and implement control software for quantum computers, design system software architecture, and ensure reliable performance in collaboration with diverse teams.

The Principal Software Engineer at Snout will define architectural direction, build features across the stack, and enhance team effectiveness, ensuring quality and performance.

Lead reliability, availability, and resiliency strategies for large-scale systems, drive operational excellence, and provide technical mentorship across engineering teams.

Senior individual contributor who architects and builds IAA's Azure-based data platform (ingestion, transformation, semantic modeling, delivery). Designs and implements complex production data pipelines, supports BI and ML workloads, sets standards, mentors engineers, and partners with business and engineering leaders to enable analytics, forecasting, and AI.

Lead software engineering efforts in developing healthcare software, focusing on microservices, code enhancement, and team collaboration while mentoring others.

As a Principal Software Engineer, you'll develop software systems for NVIDIA's rack-scale infrastructure, defining software architecture, collaborating across teams, mentoring engineers, and ensuring high-quality technical decisions in complex environments.

Lead the evolution of Backcountry's ecommerce platform, guiding architecture, mentoring teams, and driving modernization and scalability initiatives.

Design and maintain backend systems, influence technical direction, ensure scalability and reliability, mentor engineers, and improve engineering practices.

Design and operate backend systems, influence technical direction, improve practices, and mentor engineers while ensuring software scalability and reliability.

Lead technical direction for a high-performance 2D/3D viewer platform. Drive cross-team architecture, implement scalable platform capabilities, mentor engineers, improve engineering velocity, and resolve complex production issues while partnering with Product, UX, and Architects.

Lead architectural initiatives for NVIDIA's global compute platform, operationalize AI infrastructure, and drive migrations while ensuring performance and automation at scale.