Top Remote Python Jobs

Work as a Python development intern building applications and APIs, processing and analyzing data, working with databases and data pipelines, contributing to system architecture, writing clean documented code, and collaborating with the team. Strong emphasis on backend development, SQL, ORMs, and REST API design with potential conversion to full-time.

Senior backend engineer on an education-focused technology consulting team. Own complex backend systems end-to-end: estimate scope, build and support production Python services, design REST/GraphQL APIs, work with cloud and Docker, use relational databases, maintain strong automated tests and Git workflows, and represent technical work to clients. Role values mentorship, ownership, and mission-driven work.

Design and implement complex backend services for Binance Square. Collaborate with product, DevOps, and QA to deliver high-quality microservices, promote engineering best practices, and perform code reviews.

Develop Python-based solutions performing SQL/CRUD operations, file extraction/transformation/generation (CSV, XML, JSON, PDF), and email integration. Work within an onsite/offshore model, communicate effectively, and perform under pressure for contract engagements.

Design, develop, and maintain front-end (React/HTML/CSS) and back-end (Django/Python) web applications. Architect platforms, perform code/design reviews, interface with stakeholders, write documentation and tests, support deployments and system performance improvements, and build monitoring/automation tools.

Design and implement durable, fault-tolerant AI orchestration and backend systems using Temporal and agentic ReAct patterns. Deliver features end-to-end with testing, CI/CD, monitoring, and observability; mentor engineers and collaborate with cross-functional teams to translate legal workflows into reliable AI-powered features.

Design and build backend systems and APIs for AI-driven products, ensuring scalability, reliability, and integration of ML models while collaborating with engineering and product teams.

Design, build, and maintain scalable backend services with Python/Django and modern frontends with Vue.js (or React). Manage infrastructure with Terraform/CDKTF, Docker, and container orchestration; implement secrets management via 1Password CLI; contribute to CI/CD and production deployments using Uvicorn and Nginx; debug full-stack issues and mentor junior developers while participating in architecture and technical decisions.

Develop and maintain Alteryx Intelligent Services cloud and on‑prem products. Own design, implementation, testing, and contribute to DevOps pipelines and quality frameworks. Participate in code reviews, mentor teammates, collaborate with Product Management, and focus on delivering customer-centric, well-tested, performant software.

Design, build, and maintain scalable web applications and microservices using Python and React. Develop RESTful APIs, support containerized deployments and CI/CD on cloud infrastructure (primarily AWS), and integrate Generative AI/LLM capabilities. Collaborate in Agile teams through sprint planning, code reviews, and design discussions to ensure high-quality architecture and delivery.

As a Founding Staff Software Engineer, you will lead the design and development of robust backend systems and APIs, optimize large-scale data workflows, and mentor a growing engineering team.

Develop cloud-native applications, lead various projects, and utilize Python, Django, and AWS. Engage in performance tuning and systems integration efforts.

Design and implement idiomatic Python APIs and bindings for CUDA Core Libraries, develop and integrate native C/C++ components, define interoperability boundaries (Python, C/C++, Rust), optimize performance, own feature lifecycle (design through maintenance), and collaborate with compiler, runtime, and user teams to ensure correctness, usability, and performance.

Design, develop, deploy, monitor, and support APIs and system integrations (Salesforce, REST, third-party). Work directly with clients to gather requirements, troubleshoot and optimize integrations, operate solutions in AWS, collaborate with teams, and mentor junior developers.

Build and ship full‑stack features for transportation management and other client products. Design and implement APIs and UIs, collaborate with product and design, own delivery, write modular testable code, troubleshoot and iterate quickly, and mentor peers.

Develop and maintain Python applications focusing on iterators/generators/streams, concurrency (multithreading, non-blocking I/O), and high-precision numeric handling. Work with JSON/XML, REST and SOAP APIs, ACID-compliant databases, message brokers/queues, and produce clean, SOLID code. Unit and integration testing experience is beneficial.

The Forward Deployed Engineer will serve as a technical bridge between clients and engineering teams, writing custom code and integrations, while ensuring customer success with Socket's security platform through strong relationships and expert technical guidance.

Join Cerebras Systems to optimize and develop frontend compiler infrastructure for PyTorch models on their unique wafer-scale AI platform, focusing on model representation and optimization.

As a Senior Python Engineer, you'll manage and optimize investment data solutions, collaborate on design, and develop scalable data applications using emerging tools and best practices.

Design, develop, and maintain scalable Python applications and cloud-native solutions. Architect microservices, containerized deployments (Docker/Kubernetes), optimize cloud infrastructure, build CI/CD pipelines, integrate messaging systems, ensure security and high code quality, and mentor junior developers. Generative AI/ML experience is a plus.

The Senior Software Developer will redesign applications, migrate from Ab Initio to Python and Oracle SQL, and collaborate with internal teams. Responsibilities include hands-on coding, testing, and analyzing results.

Lead full-feature ownership for an AI-driven life sciences SaaS platform: design, develop, deploy, support, and maintain production-quality Python services. Collaborate with product, drive architecture and scalability, define engineering best practices, perform code reviews, and mentor engineers to grow the codebase and team.

Build and own features for a new AI-driven enterprise SaaS platform for life sciences. Design, develop, deploy, and support production Python services, collaborate on technical design, drive scalability, mentor engineers, and define engineering best practices with AI-assisted workflows.

Senior engineer who will found and grow an AI-first product team, own feature lifecycle from design to production support, drive scalable SaaS architecture, mentor engineers, perform expert code reviews, and define engineering best practices using AI-assisted tooling.

Founding member building an AI-driven life sciences SaaS platform. Own features end-to-end from design to production, contribute daily code, collaborate with product, perform expert code reviews, define engineering best practices, and mentor engineers to grow the team and deliver scalable, high-volume solutions.