Top Senior Machine Learning Jobs in Indianapolis, IN

28 Days AgoSaved
Remote
Indianapolis, IN
200K-316K Annually
Senior level
200K-316K Annually
Senior level
Cloud • Security • Software • Generative AI
Lead Elastic’s strategy, vision, and multi-quarter roadmap for vector databases, embedding and reranking models, vector indexing, semantic ingestion, and search capabilities. Conduct market and competitive research, define product metrics, prioritize features, and partner closely with engineering, cloud, and applied research teams. Guide technical trade-offs involving recall, latency, index size, ingestion throughput, model lifecycle, and total cost of ownership across serverless and self-managed deployments.
Top Skills: Approximate Nearest Neighbor (Ann) IndexingDeveloper ApisEmbeddingsGenerative ModelsHybrid RetrievalMachine LearningModel Fine-TuningSdksVector DatabasesVector IndexingVector Search
28 Days AgoSaved
Remote
Indianapolis, IN
Senior level
Senior level
AdTech • Marketing Tech • Business Intelligence
Owns a portfolio of Data-as-a-Service products end to end, including vision, roadmap, requirements, agile delivery, pricing, packaging, distribution, privacy compliance, and go-to-market execution. Partners with engineering, data science, legal, marketing, sales, and customer success to deliver data enrichment, identity, and audience products through APIs, clean rooms, marketplaces, integrations, and self-service channels. Uses launch metrics and customer insights to guide investment decisions.
Top Skills: AIAPIsAWSClean RoomsCloud Data WarehousesData MarketplacesDatabricksFile TransferJIRAMachine LearningMartech IntegrationsMcp ServersSnowflake
28 Days AgoSaved
Remote
Indianapolis, IN
170K-230K Annually
Senior level
170K-230K Annually
Senior level
Information Technology • Other • Social Media
Own the end-to-end rebuild of Nextdoor’s consumer search experience, including query understanding, retrieval, ranking, result quality, organic and sponsored content blending, and monetization. Define search relevance metrics, partner with engineering, data science, ML, research, design, and marketing teams, and use A/B testing to improve engagement and revenue while protecting user experience.
Top Skills: ChatgptClaudeGeminiGleanLarge Language Models (Llms)Machine Learning
28 Days AgoSaved
Remote
Indianapolis, IN
210K-264K Annually
Senior level
210K-264K Annually
Senior level
Cloud • Information Technology
Leads commercial, privacy, and product legal functions for a cloud technology company. Drafts and negotiates complex SaaS, partnership, reseller, and technology agreements; advises on global privacy, data protection, AI, intellectual property, and product development issues; develops contracting processes and playbooks; partners with cross-functional teams; and manages, mentors, and develops legal professionals.
Top Skills: Artificial IntelligenceCcpaCloud ServicesGdprMachine LearningSaaS
28 Days AgoSaved
Remote or Hybrid
Indianapolis, IN
100K-186K Annually
Senior level
100K-186K Annually
Senior level
Fintech • Financial Services
Develops, calibrates, validates, and maintains credit risk models, including PD, LGD, and EAD models, for lending, collections, loss forecasting, capital planning, and stress testing. Analyzes large datasets, evaluates model performance, documents model changes, supports systems testing, and communicates statistical insights to stakeholders and management. Collaborates across the credit union to improve risk-return strategies and reporting.
Top Skills: Artificial IntelligenceLogistic RegressionMachine LearningMarkov Chain AnalysisMonte Carlo SimulationPythonRSASSQLSurvival AnalysisTime Series Analysis
Reposted 28 Days AgoSaved
Remote
Indianapolis, IN
170K-234K Annually
Senior level
170K-234K Annually
Senior level
AdTech • Marketing Tech
Lead design and implementation of high-throughput, low-latency programmatic bidding systems. Collaborate with ML engineers to deploy real-time inference, optimize distributed microservices, run experiments and quantitative analysis, and partner with product to ship scalable features. Foster operational excellence, mentor engineers, and continuously improve performance and reliability.
Top Skills: C++Data PipelinesDatabasesDistributed SystemsGoGpu ProgrammingJavaMachine LearningMicroservicesRustScala
28 Days AgoSaved
Remote
Indianapolis, IN
Senior level
Senior level
Artificial Intelligence • Cloud • Information Technology • Machine Learning • Software • Sports • Analytics
Own the product strategy, roadmap, team, customer relationships, and P&L for Teamworks’ Coaching, Player Personnel, Recruiting, and Intelligence portfolio. Lead AI strategy across sports markets, integrate acquired products, align engineering, design, data science, marketing, and sales, and convert proprietary sports data into AI-powered workflows. Represent the business with teams, leagues, and partners while driving multi-market growth and product execution.
Top Skills: Agentic AiAIB2B SaasData ScienceMachine LearningProprietary Data Models
28 Days AgoSaved
Remote
Indianapolis, IN
Senior level
Senior level
Software • Automation
Leads technical sales and executive evangelism for Verint’s Open CCaaS and CX Automation platform. Acts as a trusted advisor to C-suite customers, articulating ROI, AI, data science, and platform capabilities. Partners with Product, Sales, Solutions, Services, Marketing, and Customer Success teams to drive adoption, expansion, thought leadership, and opportunity closure. Requires deep contact center operations experience, strong data architecture knowledge, executive communication skills, and extensive travel.
Top Skills: Amazon Web ServicesCdpCRMData LakesData ScienceData WarehousesErpGoogle Cloud PlatformMachine LearningAzureSnowflakeVerint Davinci AiVerint Engagement Data HubVerint Open Ccaas
15 Days AgoSaved
In-Office
Indianapolis, IN
144K-231K Annually
Senior level
144K-231K Annually
Senior level
Healthtech • Biotech • Pharmaceutical
Lead end-to-end ownership of CMC data products and AI/ML solutions, including data governance, architecture, pipelines, semantic models, AI interfaces, validation frameworks, and production scaling. Partner with data engineering, analytics, IT, and senior stakeholders to move AI capabilities from MVP to enterprise use, ensure regulatory and privacy compliance, define technical standards, and drive adoption through compelling business communication.
Top Skills: Ai/MlAws SagemakerAzure MlCloud HostingComputer VisionGoogle Ai PlatformIdentity-Based Access ControlMlopsNatural Language ProcessingPower BIRow-Level SecuritySemantic Modeling
One Month AgoSaved
Remote or Hybrid
Indianapolis, IN
120K-180K Annually
Senior level
120K-180K Annually
Senior level
Cloud • Computer Vision • Information Technology • Sales • Security • Cybersecurity
Lead research and engineering of production-grade LLM/GenAI systems for cybersecurity: design models and architectures, drive data labeling and evaluation, collaborate with product and engineering to deploy scalable solutions, mentor data scientists, set technical strategy, and advance AI safety, red-teaming, and applied ML innovations for detection and operational use.
Top Skills: Cloud TechnologiesDeep Learning FrameworksGenaiGpu TechnologiesLlmsPython
One Month AgoSaved
Remote or Hybrid
Indianapolis, IN
140K-215K Annually
Senior level
140K-215K Annually
Senior level
Cloud • Computer Vision • Information Technology • Sales • Security • Cybersecurity
Lead development and deployment of large-scale LLM and GenAI solutions for cybersecurity. Drive research strategy, model training, evaluation, safety/red-teaming, and cross-functional productization. Mentor data scientists, set technical standards, and represent the team through publications and thought leadership.
Top Skills: Cloud TechnologiesDeep Learning FrameworksGenerative AiGpu TechnologiesLlmsPython
Reposted One Month AgoSaved
Easy Apply
Remote or Hybrid
Indianapolis, IN
Easy Apply
179K-319K Annually
Senior level
179K-319K Annually
Senior level
Artificial Intelligence • Cloud • Computer Vision • Hardware • Internet of Things • Software
As a Staff Machine Learning Engineer, you will design AI products on Edge devices, optimize ML model performance, and work with large-scale datasets, collaborating across teams to deliver impactful solutions.
Top Skills: C++PythonRayRustSpark
New

Track Smarter, Apply Better.

Ditch the spreadsheets. Organize your job search with our freeApplication Tracker.

Use For Free
Application Tracker Preview
Reposted One Month AgoSaved
Remote
Indianapolis, IN
160K-220K Annually
Senior level
160K-220K Annually
Senior level
Artificial Intelligence • Machine Learning • Natural Language Processing • Software • Conversational AI
As an ML Ops Infrastructure Engineer, you will design CI/CD pipelines for ML, maintain deployment systems, and implement monitoring while collaborating with research teams to ensure model quality and performance.
Top Skills: Ci/CdDatadogDockerGrafanaKubernetesNvidia Triton Inference ServerOnnx RuntimePrometheusPulumiPythonTensorrtTerraform
Reposted One Month AgoSaved
Remote
Indianapolis, IN
160K-239K Annually
Senior level
160K-239K Annually
Senior level
Artificial Intelligence • Machine Learning • Natural Language Processing • Software • Conversational AI
As a Systems Architect, you'll define and drive the infrastructure architecture for AI/ML workloads, design multi-cloud strategies, manage compute orchestration and storage systems, and lead capacity planning, while also collaborating with engineering leadership.
Top Skills: AIAWSCloud ServicesContainer OrchestrationGpu InfrastructureKubernetesMlStorage Systems
Reposted One Month AgoSaved
Remote
Indianapolis, IN
136K-240K Annually
Senior level
136K-240K Annually
Senior level
Artificial Intelligence • Machine Learning • Natural Language Processing • Software • Conversational AI
The engineer will build and operate AI/ML infrastructure, managing services on AWS and bare metal, using tools like Kubernetes and Terraform.
Top Skills: AWSBashGoKubernetesPythonSlurmTerraform
Reposted 28 Days AgoSaved
Remote
Indianapolis, IN
150K-195K Annually
Senior level
150K-195K Annually
Senior level
Software • Cryptocurrency • Web3
Lead product analytics to improve user growth, engagement, retention, and revenue. Design and analyze A/B and multivariate experiments, perform funnel/cohort analyses, maintain KPIs and dashboards, ensure event tracking, leverage ML and AI tools for advanced analyses, and translate insights into product recommendations across cross-functional teams.
Top Skills: A/B TestingAi-Assisted ToolsMachine LearningMultivariate TestingPropensity ScoringPythonRSegmentationSQLTableau
Reposted 28 Days AgoSaved
Remote or Hybrid
Indianapolis, IN
123K-193K Annually
Senior level
123K-193K Annually
Senior level
Fintech • Financial Services
Lead design and scaling of a unified fraud and risk platform. Define product strategy, own fraud metrics, run SQL-driven analysis and A/B tests, and partner with engineers and data teams to build real-time detection, identity verification, and transaction monitoring. Balance customer experience with risk mitigation and communicate impact to executives, legal, and partners.
Top Skills: A/B TestingAPIsArtificial IntelligenceBehavioral AnalyticsBlockchainData PipelinesDevice FingerprintingIdentity VerificationMachine LearningRiskifiedSardineSQLTransaction Monitoring
Reposted 28 Days AgoSaved
In-Office or Remote
Indianapolis, IN
Senior level
Senior level
Consulting • Financial Services
Design and lead end-to-end AI solution architectures, ensuring scalability, security, and compliance. Translate business and regulatory requirements into technical designs, evaluate tools/platforms, document architecture standards, coordinate technical teams, and support deployment and ongoing improvements.
Top Skills: AIAPIsCloud PlatformsData ArchitectureGenerative AiIntegration PatternsIntelligent AutomationMachine LearningSecure Solution Design
Reposted 28 Days AgoSaved
Remote
Indianapolis, IN
115K-130K Annually
Senior level
115K-130K Annually
Senior level
Edtech
Lead complex, cross-functional AI programs end-to-end: translate strategy into integrated plans, drive multi-team execution, mitigate risks (data, model, compliance), apply ML lifecycle practices, use Agile/kanban methods, manage budgets/vendors, communicate to senior stakeholders, and mentor other program managers to improve AI program standards.
Top Skills: AgileAIData PlatformsKanbanMachine LearningMachine Learning PlatformsMl LifecycleResponsible AiScrum
Reposted 28 Days AgoSaved
Remote
Indianapolis, IN
219K-301K Annually
Senior level
219K-301K Annually
Senior level
Big Data • Machine Learning • Software • Analytics • Big Data Analytics
Lead technical pre-sales for large Oil, Gas & Energy accounts, define and implement Databricks-based data and ML/AI strategies, build technical champions, mentor teammates, and drive enterprise adoption through technical leadership and value selling.
Top Skills: AISparkBig DataCloudDatabricksDelta LakeJavaMachine LearningMlflowPythonRScala
6 Days AgoSaved
Remote
Indianapolis, IN
Senior level
Senior level
Healthtech • Information Technology • Consulting
Designs enterprise AI/ML architectures, reference architectures, MLOps standards, lifecycle controls, and technical playbooks for the Veterans Health Administration. Provides consultation to AI pilot teams, evaluates vendor solutions, supports AI catalog and center-of-excellence planning, and translates federal security, authorization, interoperability, and risk requirements into executable architecture decisions. The role is remote and requires collaboration with program leaders, engineers, vendors, and VA IT teams.
Top Skills: Amazon Web Services (Aws)Automated RetrainingCi/CdDrift DetectionEhrFeature StoresFedrampFhirGCPHl7AzureMlopsModel CardsModel MonitoringModel RegistryOmopVa Arches
6 Days AgoSaved
Remote
Indianapolis, IN
Senior level
Senior level
Healthtech • Information Technology • Consulting
Designs enterprise AI/ML architecture and product-management pipelines across the model lifecycle. Establishes MLOps standards, governance, risk management, monitoring, explainability, and compliance practices for responsible AI deployment at the VA. Advises governance bodies and senior leadership, evaluates tooling and platforms, supports CI/CD integration, and collaborates with engineering, data science, and product teams on scalable ML systems.
Top Skills: Ai/MlAmazon SagemakerAutomated TestingAws GovcloudAzure MlCdwCi/CdDatarobotFedrampGoogle Cloud Government OfferingsHipaaKubeflowMicrosoft Azure GovernmentMlflowMlopsModel VersioningNist Ai RmfPipeline OrchestrationVinciVista
6 Days AgoSaved
Remote
Indianapolis, IN
Senior level
Senior level
Healthtech • Information Technology • Consulting
Lead statistical modeling, AI/ML evaluation, data governance, data quality assurance, and executive analytics for VA EHR modernization. Build reproducible R-based analytics, reporting pipelines, dashboards, and governed data products using R, SQL, Python, Git, and cloud platforms. Evaluate model reliability, bias, drift, and operational value; integrate complex healthcare data; define metrics and validation rules; and advise stakeholders on auditable analytical practices.
Top Skills: Ai AgentsBertopicConfluenceDatabricksDelta TablesGitGitJIRALlmsAzureNlpPower BIPythonRR PackagesRagSASServicenowSQL
Reposted 6 Days AgoSaved
Remote
Indianapolis, IN
200K-200K Annually
Senior level
200K-200K Annually
Senior level
Information Technology • Professional Services • Database
Designs and operates production multi-agent AI systems, LLM workflows, scoring and optimization algorithms, and closed-loop autonomous processes. Responsibilities include AI model evaluation, production monitoring, governance, third-party AI integration, federated data retrieval, and identifying patentable inventions. The role requires deep machine learning expertise, algorithm development, and deployment experience across complex operational environments.
Top Skills: AutogenCrewaiDigital TwinsEmbeddingsFederated LearningIotJaxKnowledge GraphsLangchainLanggraphLarge Language ModelsMlflowMulti-Agent AiPythonPyTorchRayReinforcement LearningRetrieval-Augmented GenerationSemantic SearchVector DatabasesWeights & Biases
6 Days AgoSaved
Remote
Indianapolis, IN
118K-331K Annually
Senior level
118K-331K Annually
Senior level
Insurance
Leads Mercury’s cross-line AI/ML research capability across insurance products. Responsibilities include setting strategy, building a research tooling team, modernizing workflows, developing model monitoring and AI infrastructure, establishing responsible AI guardrails, partnering across technology and data science teams, driving adoption, and coaching talent. The role requires strong quantitative, insurance analytics, Python, machine learning, generative AI, and LLM evaluation expertise, along with substantial people and cross-functional leadership experience.
Top Skills: Ai HarnessAi/Ml InfrastructureData PipelinesFeature WorkflowsGenerative AiLarge Language ModelsLlm EvaluationMachine Learning FrameworksModel MonitoringPython
All Filters
JobType
New Jobs
Job Category
Experience
Industry
Company Name
Company Size

Sign up now Access later

Create Free Account